Completed Study, Fall 2025
Trends In Breast-Cancer Diagnosis Age And Hereditary or Non-Hereditary Diagnoses, Using The All of Us Database
Mentor: Dr. Rebecca Kronk from Duquesne University
Research Paper
Breast cancer begins when a malignant tumor forms in the tissue of the breast. It affects one in eight women, or roughly thirteen percent of the female population. Anywhere from five to ten percent of women who are diagnosed have a familial history of breast cancer, while the other ninety percent is caused by random mutations of genes, most commonly BRCA1/2 genes. Breast cancer is most commonly found in older women, approximately 62 years old, and nine percent of cases are in women under 45. However, it is not fully known if the age at which a patient is diagnosed with breast cancer is correlated to if the breast cancer a patient has is hereditary or randomly occurring. For this study I hypothesised that women under 50 years old will express hereditary breast cancer, and women over the age of 50 will express non-hereditary breast cancer.