Centrosome
Centrosome and Cilium
The Liu Centrosome & Cilium Lab (LCCL) seeks to uncover the blueprint that cells use to build centrosomes and cilia, and to understand how defects in these processes contribute to human health and diseases.
Imagine building a LEGO space station (top image on the left). The perfect blueprint is essential.
The centrosome can be construed as a massive molecular space station. It is built with remarkable precision from approximately 200 different proteins, almost all of which exist in multiple copies.
The cilium is a hair-like antenna that extends from the centrosome (bottom image on the left) and acts as a local communication hub allowing the cell to sense external stimuli.
We are interested in the fundamental principles that govern organelle architecture and how cells reorganize and adapt their organelles in response to environmental and developmental cues.
The Liu Centrosome & Cilium Lab opens in Department of Pharmacological Sciences at Stony Brook University in April, 2026.
We are hiring at all levels! Applicants are encouraged to reach out to Harry at yue.liu.2@stonybrook.edu