(245) A. Damico, C. R. Mathus, A. V. Demchenko. Application of the hydrogen-bond-mediated aglycone delivery (HAD) reaction to the synthesis of α- and β-linked 2-azidoglucosides. Chem. Asian J., 2026, 21, e70928 (special issue) 1st in AY2026-7
PMID: 42572209 (4NSF-9)
https://doi.org/10.1002/asia.70928
(244) L. M. Ridgway, R. L. Turecki, F. Pooladian, A. Das, A. V. Demchenko. Activation of thioglycosides with ferric chloride: scope and mechanism. ACS Omega, 2026, 11, 33123-33133
PMID: 42294148 (R35-13)
https://doi.org/10.1021/acsomega.6c03149
(243) A. Damico, N. Y. Asuama, S. A. Geringer, N. P. Rath, C. De Meo, A. V. Demchenko. First evidence of the H-bonding with picoloylated compounds used as building blocks for HAD. Carbohydr. Res., 2026, 566, 109962 (special issue)
PMID: 42127496 (4NSF-8)
https://doi.org/10.1016/j.carres.2026.109962
(242) J. A. Talbert, T. L. Kalmer, L. S. Cantrell, M. D. Bandara, A. V. Demchenko, A. S. Walker, J. A. Gaddy, S. D. Townsend. Human milk oligosaccharides inhibit group B Streptococcal growth by binding PcsB, an essential cell wall separation protein. JACS Au, 2026, 6, 2355-2366
PMID: 42063812 (R35-12)
https://doi.org/10.1021/jacsau.5c01741
(241) T. Khamkhenshorngphanuch, G. A. Kashiwagi, Y. Sutar, S. Theeramunkong, N. Srimongkolpithak, A. V. Demchenko. Real-time reaction monitoring of silylation and acylation of carbohydrates with a conductometry set-up. Carbohydr. Res., 2026, 563, 109853 (special issue)
PMID: 41719751 (R35-11)
https://doi.org/10.1016/j.carres.2026.109853
(240) A. Das, G. A. Kashiwagi, Q. Gan, M. L. Shadrick, A. M. Montaño, A. V. Demchenko. Synthesis and characterization of differentially sulfated disaccharide repeating units of keratan sulfate. Glycoscience & Therapy, 2026, 2, 100023
PMID: 41970450 (R35-10)
(239) A. Das, C. De Meo, A. V. Demchenko. Chemical synthesis of human milk oligosaccharides: sialyllacto-N-tetraose a (LSTa). J. Org. Chem., 2025, 90, 18224-18233
PMID: 41379655 (R35-9)
https://doi.org/10.1021/acs.joc.5c02428
(238) D. J. Hoard, Y. Sutar, A. V. Demchenko. Differentially substituted galactosyl chlorides reveal unusual reactivity trends under the 4K reaction conditions. J. Org. Chem., 2025, 90, 16121-16130
PMID: 41190356 (4NSF-7)
https://doi.org/10.1021/acs.joc.5c02093
Correction: J. Org. Chem., 2026, 91, 7380
https://doi.org/10.1021/acs.joc.6c01001
PMID: 42136185
(237) N. P. Forsythe, G. R. Gochenour, G. A. Kashiwagi, A. V. Demchenko. Chemoselective activation of thioglycosides with alkyl trichloroacetimidates. J. Org. Chem., 2025, 90, 13832-13843
PMID: 40985207 (4NSF-6)
https://doi.org/10.1021/acs.joc.5c01510
Correction: J. Org. Chem., 2026, 91, 7380
https://doi.org/10.1021/acs.joc.6c01000
PMID: 42133858
(236) A. R. Dent, A. M. DeSpain, A. V. Demchenko. Cooperatively catalyzed activation of thioglycosides with iodine and iron(III) trifluoromethanesulfonate. Molecules, 2025, 30, 3058 (special issue)
PMID: 40807233 (4NSF-5)
https://doi.org/10.3390/molecules30153058
(235) G. A. Kashiwagi and A. V. Demchenko. Enhanced experimental set-up for HPLC-based automated synthesis and purification of carbohydrate building blocks. Carbohydr. Res., 2025, 555, 109554 (Special issue) 1st in AY2025-6
PMID: 40480011 (R35-8)
https://doi.org/10.1016/j.carres.2025.109554
(234) F. Pooladian, A. Das, A. V. Demchenko. Chemical synthesis of two fucosylated human milk oligosaccharides: 3-fucosyllactose and lacto-N-fucopentaose V. Chem. Eur. J., 2025, 31, 202500754
PMID: 40261993 (R35-7)
http://dx.doi.org/10.1002/chem.202500754
(233) A. R. Dent and A. V. Demchenko. Halophilic metal salts for the cooperatively catalyzed activation of thioglycosides. J. Org. Chem., 2025, 90, 6478–6490
PMID: 40323631 (4NSF-4)
http://dx.doi.org/10.1021/acs.joc.5c00311
Correction: https://doi.org/10.1021/acs.joc.6c00999
PMID: 42153526
(232) A. Das, S. Adio, J. Brincken, A. V. Demchenko, C. De Meo. Sialylation reactions: expanding the C-5 effect to phosphate leaving groups. Carbohydr. Res., 2025, 548, 109353 (Special issue)
PMID: 39700596 (R35-6, 4NSF-3)
(231) L. M. Ridgway, A. Das, M. L. Shadrick, A. V. Demchenko. Ferric Chloride Promoted Glycosidation of Alkyl Thioglycosides. Molecules, 2024, 29, 4845 (Special issue)
PMID: 39459213 (R35-5, 4NSF-2)
https://doi.org/10.3390/molecules29204845
(230) A. V. Demchenko. HPLC-based automation of carbohydrate synthesis. Glycoforum, 2024, 27, A20
https://doi.org/10.32285/glycoforum.27A20
https://www.glycoforum.gr.jp/article/27A20.html
(229) F. Pooladian, A. Das, J. W. Wise, A. V. Demchenko. Synthesis of regioselectively protected building blocks of benzyl β-D-glucopyranoside. Carbohydr. Res., 2024, 544, 109250 (Special issue)
PMID: 39214041 (R35-4)
https://doi.org/10.1016/j.carres.2024.109250
(228) G. A. Kashiwagi, L. Petrosilli, S. Escopy, L. Lay, K. J. Stine, C. De Meo, A. V. Demchenko. HPLC-based automated synthesis and purification of carbohydrates. Chem. Eur. J., 2024, 30, e202401214
PMID: 38684455 (U01-29, 2R01-35, R35-3)
http://doi.org/10.1002/chem.202401214
Front cover picture:
https://doi.org/10.1002/chem.202402504
(227) A. Damico, G. Shrestha, A. Das, K. J. Stine, A. V. Demchenko. SFox imidates as versatile glycosyl donors for chemical glycosylation. Org. Biomol. Chem., 2024, 22, 5214-5223
PMID: 38867654 (2R01-34, R35-2)
https://doi.org/10.1039/D4OB00679H
(226) D. J. Hoard, Y. Sutar, A. V. Demchenko. Direct synthesis of glycosyl chlorides from thioglycosides. J. Org. Chem., 2024, 89, 6865-6876
PMID: 38669055 (2R01-33, R35-1)
https://doi.org/10.1021/acs.joc.4c00244
(225) A. V. Demchenko and C. De Meo. The 4K reaction. Carbohydr. Res., 2024, 538, 109102 (special issue)
PMID: 38569333 (3NSF-31, 4NSF-1)
https://doi.org/10.1016/j.carres.2024.109102
(224) N. P. Forsythe, E. R. Mize, G. A. Kashiwagi, A. V. Demchenko. Expedient synthesis of superarmed glycosyl donors via oxidative thioglycosidation of glycals. Synthesis, 2024, 56, 1147-1156 (Cover page article for the special issue on emerging trends in glycoscience)
PMID: 38655286 (2R01-32, 3NSF-30, T32-2)
(223) Y. Singh, S. Escopy, M. Shadrick, M. D. Bandara, K. J. Stine, A. V. Demchenko. Chemical synthesis of human milk oligosaccharides: para-lacto-N-hexaose and para-lacto-N-neohexaose. Chem. Eur. J., 2023, 29, e202302288
PMID: 37639512 (2R01-31)
http://doi.org/10.1002/chem.202302288
(222) A. Romerio, A. R. Franco, M. Shadrick, M. M. Shaik, V. Artusa, A. Italia, F. Lami, A. V. Demchenko, F. Peri. Overcoming challenges in chemical glycosylation to achieve innovative vaccine adjuvants possessing enhanced TLR4 activity. ACS Omega, 2023, 8, 36412-36417
PMID: 37810727
https://doi.org/10.1021/acsomega.3c05363
(221) A. Dent, S. Escopy, A. V. Demchenko. Cooperatively catalyzed activation of thioglycosides that bypasses intermediacy of glycosyl halides. Chem. Eur. J., 2023, 29, e202300873
PMID: 37154481 (2R01-30, 3NSF-29)
http://dx.doi.org/10.1002/chem.202300873
(220) N. Forsythe, L. Liu, G. A. Kashiwagi, A. V. Demchenko. Activation of thioglycosides under mild alkylation conditions. Carbohydr. Res., 2023, 531, 108872 (Special issue)
PMID: 37348387 (2R01-29, T32-1)
https://doi.org/10.1016/j.carres.2023.108872
(219) P. Sondhi, D. Neupane, J. K. Bhattarai, H. Ali, A. V. Demchenko, K. J. Stine. Versatile technique to produce a hierarchical design in nanoporous gold. J. Vis. Exp., 2023, 192, e65065
PMID: 36847406 (2R01-28)
(218) P. Sondhi, D. Lingden, J. K. Bhattarai, A. V. Demchenko, K. J. Stine. Applications of nanoporous gold in therapy, drug delivery, and diagnostics. Metals, 2023, 13, 78
PMID: 39238564 (2R01-27)
(217) F. Pooladian, S. Escopy, A. V. Demchenko. Activation of thioglycosides with copper(II) bromide. Molecules, 2022, 27, 7354 (Special issue)
PMID: 36364179 (2R01-26)
https://doi.org/10.3390/molecules27217354
(216) P. Sondhi, D. Neupane, J. K. Bhattarai, A. V. Demchenko, K. J. Stine. Facile fabrication of hierarchically nanostructured gold electrode for bio-electrochemical applications. J. Electroanal. Chem., 2022, 116865
PMID: 36405880 (2R01-25)
https://doi.org/10.1016/j.jelechem.2022.116865
(215) M. Shadrick, K. J. Stine, A. V. Demchenko. Expanding the scope of stereoselective α-galactosylation using glycosyl chlorides. Bioorg. Med. Chem., 2022, 73, 117031 (Special issue)
PMID: 36202065 (2R01-24)
https://doi.org/10.1016/j.bmc.2022.117031
(214) M. Novakova, A. Das, C. Alex, A. V. Demchenko. Synthesis and glycosidation of building blocks of D-altrosamine. Front. Chem., 2022, 10, 945779
PMID: 36226114 (2R01-23)
https://doi.org/10.3389/fchem.2022.945779
(213) S. A. Geringer, G. A. Kashiwagi, A. V. Demchenko. Broadening the scope of the reverse orthogonal strategy for oligosaccharide synthesis. J. Org. Chem., 2022, 87, 9887-9895
PMID: 35862424 (2R01-22)
https://doi.org/10.1021/acs.joc.2c00905
(212) Y. Singh, S. A. Geringer, A. V. Demchenko. Synthesis and glycosidation of anomeric halides: evolution from early studies to modern methods of the 21st century. Chem. Rev., 2022, 122, 11701-11758
PMID: 35675037 (2R01-21, 3NSF-28)
https://doi.org/10.1021/acs.chemrev.2c00029
(211) S. Escopy, Y. Singh, K. J. Stine, A. V. Demchenko. HPLC-based automated synthesis of glycans in solution. Chem. Eur. J., 2022, 28, e202201180
PMID: 35513346 (2R01-20)
http://doi.org/10.1002/chem.202201180
(210) O. Slater, K. B. Dhami, G. Shrestha, M. Kontoyianni, M. R. Nichols, A. V. Demchenko. Development of a simple and effective Lipid-A antagonist based on computational prediction. ACS Infect. Dis., 2022, 8, 1171-1178 (Special issue)
PMID: 35612826 (2R01-19)
https://doi.org/10.1021/acsinfecdis.2c00125
(209) G. Shrestha, M. Panza, Y. Singh, K. J. Stine, A. V. Demchenko. N-Alkylated analogues of indolylthio glycosides as glycosyl donors with enhanced activation profile. Eur. J. Org. Chem., 2022, 2022, e202200300 (Special issue)
PMID: 36339352 (3NSF-27, 2R01-18)
http://doi.org/10.1002/ejoc.202200300
(208) S. Escopy and A. V. Demchenko. Transition-metal-promoted activation of thioglycosides and related compounds. Chem. Eur. J., 2022, 28, e202103747
PMID: 34935219 (3NSF-26)
http://doi.org/10.1002/chem.202103747
(207) C. Alex and A. V. Demchenko. Direct synthesis of glycans containing challenging ManNAcA residues. J. Org. Chem., 2022, 87, 271-280
PMID: 34928148 (3NSF-25)
https://doi.org/10.1021/acs.joc.1c02351
(206) G. Shrestha, G. A. Kashiwagi, K. J. Stine, A. V. Demchenko. Streamlined access to carbohydrate building blocks: methyl 2,4,6-tri-O-benzyl-α-D-glucopyranoside. Carbohydr. Res., 2022, 511, 108482 (Special issue)
PMID: 34856429 (2R01-17)
(205) C. Alex and A. V. Demchenko. Recent advances in stereocontrolled mannosylation: focus on glycans comprising acidic and/or amino sugars. Chem. Rec., 2021, 21, 3278-3294
PMID: 33885577 (3NSF-24)
https://doi.org/10.1002/tcr.202100201
(204) M. Shadrick, M. Panza, Vijaya Ganesh N., S. G. Pistorio, K. J. Stine, A. V. Demchenko. HPLC-based automated oligosaccharide synthesis. In Comprehensive Glycoscience, 2nd Edition, J.J. Barchi EIC, Elsevier, 2021, vol 2, 623-636 (2R01-16, U01-28)
Also included in the Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2020
https://doi.org/10.1016/B978-0-12-819475-1.00006-7
(203) H. B. Steber, Y. Singh, A. V. Demchenko. Bismuth(III) triflate as a novel and efficient activator for glycosyl halides. Org. Biomol. Chem., 2021, 19, 3220-3233
PMID: 33885577 (2R01-15, 3NSF-23)
https://doi.org/10.1039/D1OB00093D
(202) C. Alex, S. Visansirikul, A. V. Demchenko. A versatile approach to the synthesis of glycans containing mannuronic acid residues. Org. Biomol. Chem., 2021, 19, 2731-2743
PMID: 33687051 (3NSF-22)
https://doi.org/10.1039/D1OB00188D
(201) S. Escopy, Y. Singh, A. V. Demchenko. Palladium(II)-assisted activation of thioglycosides. Org. Biomol. Chem., 2021, 19, 2044-2054
PMID: 33599667 (2R01-14, 3NSF-21)
https://doi.org/10.1039/D1OB00004G
(200) J. K. Bhattarai, D. Neupane, B. Nepal, A. V. Demchenko, K. J. Stine. Nanoporous gold monolith for high loading of unmodified doxorubicin and sustained co-release of Doxorubicin-Rapamycin. Nanomaterials, 2021, 11, 208
PMID: 33467416 (2R01-13)
https://doi.org/10.3390/nano11010208
(199) M. Panza, M. P. Mannino, A. V. Demchenko, K. N. Baryal. Synthesis and characterization of 4-methylphenyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-galactopyranoside. In “Carbohydrate Chemistry: Proven Synthetic Methods,” Volume 5, P. Kosma, T. M. Wrodnigg, A. Stutz Eds., CRC Press, Boca Raton, 2021, 163-172 (3NSF-20, U01-27)
https://doi.org/10.1201/9781351256087
(198) S. Escopy, Y. Singh, K. J. Stine, A. V. Demchenko. A Streamlined regenerative glycosylation reaction: direct, acid-free activation of thioglycosides. Chem. Eur. J., 2021, 27, 354-361 (Hot Paper)
PMID: 32804435 (2R01-12, U01-26)
https://doi.org/10.1002/chem.202003479
(197) M. P. Mannino and A. V. Demchenko. Hydrogen-bond-mediated Aglycone Delivery (HAD) and related methods in carbohydrate chemistry. In “Carbohydrate Chemistry: Chemical and Biological Approaches,” Volume 44 (Specialist Periodical Reports), A. P. Rauter, T. K. Lindhorst, and Y. Queneau Eds., RSC, 2021, 93-116 (3NSF-19)