Article: scienmag.com/stress-and-dream-sleep-are-linked-to-pathways-of-brain-cell-death-and-survival/.
The title of the article is called “Stress And Dream Sleep Are Linked To Pathways Of Brain Cell Death And Survival” by Natasha Meredith. In the article, it talks about the first consequence of daily mild stress is the increase in rapid-eye-movement (REM) sleep. For those who don’t know what REM sleep is, it is a “sleep state during which we have most of our dreams and is involved in the regulation of emotions and memory consolidation”. Researchers from the Surrey Sleep Research Center at the University of Surrey in collaboration with Eli Lilly conducted a 9-week study where mice were exposed to a variety of mild stressors. The mice showed signs of depression which made them less likely to participate in activities such as eating food or being social with other mice they haven’t encountered. While monitoring the mice’s sleep patterns, the researchers have found that there was an increase in the duration and continuity of REM sleep. In the article, it states that “changes in REM sleep were very tightly linked to a deficiency in the regulation of the stress hormone corticosterone”. In order to further the understanding the link between stress, the stress hormone, REM sleep, and gene expression, the researchers took a novel-machine approach which identified groups of genes that can predict observed sleep, hormonal, and behavioral characteristics. A revelation was revealed that REM sleep, the regulation of the stress hormone, and a behavioral sign of depression became closely associated with the molecular pathways of death and survival of cells in the brain.