Z. John Daye

"There are no limits." - Bruce Lee

Raleigh, NC

Email: zhongyindaye AT gmail DOT com

Experiences

• 2019 - Present: Fund Manager, San Marino Asset Management, LLC

• 2015 - 2016: Adjunct Assistant Professor, University of Arizona

• 2012 - 2015: Assistant Professor, University of Arizona

• 2009 - 2012: Postdoctoral Researcher, University of Pennsylvania

• 2001: Technical Intern, Amazon.com

• 2000 - 2001: Co-Founder and President, Futera, Inc.

Education

• 2004 - 2009: Ph.D. in Statistics, Purdue University

• 2002 - 2003: M.S. in Financial Engineering, Columbia University

• 1999 - 2001: B.S. in Electrical Engineering and Computer Sciences with High Honors, UC Berkeley

• 1997 - 1999: B.S. in Bioengineering in progress, UC San Diego

Research Interests

• High-Dimensional Statistics

• Machine Learning

• Computational Biology

• Bioinformatics

Peer-Reviewed Journal Articles

(# corresponding author, * graduate students)

1. Di Ran* and Z. John Daye^# (2017). Gene Expression Variability and the Analysis of Large-Scale RNA-Seq Studies with the MDSeq. Nucleic Acids Research. 45 (13): e127. (R Code, Vignette)

2. Jing Zhai*, Chiu-Hsieh Hsu, Z. John Daye^# (2017). Ridle for Sparse Regression with Mandatory Covariates with Application to the Genetic Assessment of Histologic Grades of Breast Cancer. BMC Medical Research Methodology. 17(12). (R/Fortran Code)

3. X. Jessie Jeng, Z. John Daye, Wenbin Lu, Jung-Ying Tzeng (2016). Rare Variants Association Analysis in Large-Scale Sequencing Studies at the Single Locus Level. PLoS Computational Biology. 12(6): e1004993. (R/Fortran Code)

4. E.O. Melo, D.M. Cordeiro, R. Pellegrino, Z. Wei, Z. John Daye, R.C. Nishimura, M.A. Dode (2016). Identification of Molecular Markers for Oocyte Competence in Bovine Cumulus Cells. Animal Genetics. DOI:10.1111/age.12496.

5. I. Petkovska, D.R. Martin, M.F. Covington, S. Urbina, E. Duke, Z. John Daye, L.A. Stolz, S.M. Keim, J.R. Costello, S. Chundru, H. Arif-Tiwari, D. Gilbertson-Dahdal, L. Gries, B. Kalb (2016). Accuracy of Unenhanced MR Imaging in the Detection of Acute Appendicitis: Single-Institution Clinical Performance Review. Radiology. 279(2): 451-460.

6. E. Duke, B. Kalb, H. Arif-Tiwari, Z. John Daye, D. Gilbertson-Dahdal, S.M. Keim, D.R. Martin (2016). A Systematic Review and Meta-Analysis of Diagnostic Performance of MRI for Evaluation of Acute Appendicitis. American Journal of Roentgenology. 206(3): 508-517.

7. E. Cantu, R.J. Shah, W. Lin, Z. John Daye, J.M. Diamond, Y. Suzuki, J.H. Ellis, C.F. Borders, G.A. Andah, B. Beduhn, N.J. Meyer, M. Ruschefski, R. Aplenc, R. Feng, J.D. Christie (2015). Oxidant Stress Regulatory Genetic Variation in Recipients and Donors Contributes to Risk of Primary Graft Dysfunction after Lung Transplantation. J. Thorac. Cardiovasc. Surg. 149(2): 596-602.

8. H. Hu, M. Nau, P. Ehrenberg, A.-L. Chenine, C. Macedo, Y. Zhou, Z. John Daye, Z. Wei, M. Vahey, N.L. Michael, J.H. Kim, M. Marovich, and S. Ratto-Kim (2013). Distinct gene expression profiles associated with the susceptibility of pathogen-specific CD4+ T cells to HIV-1 infection. Blood. 121 (7): 1136-1144.

9. Z. John Daye, Hongzhe Li, and Zhi Wei (2012). A Powerful Test for Multiple Rare Variants Association Studies that Incorporates Sequencing Qualities. Nucleic Acids Research. 40 (8): e60. (PDF, R Code)

10. Z. John Daye, Jinbo Chen, and Hongzhe Li (2012). High-Dimensional Heteroscedastic Regression with Applications in eQTL Data Analysis. Biometrics. 68 (1): 316-326. (PDF, Fortran/R Code)

11. Z. John Daye^#, Jichen Xie*, and Hongzhe Li (2012). A Sparse Structured Shrinkage Estimator for Nonparametric Varying-Coefficient Model with an Application in Genomics. Journal of Computational and Graphical Statistics. 21 (1): 110-133. (PDF, Appendix, Fortran/R Code)

12. R. Pellegrino, D.Y. Sunaga, C Guindalini, R.C.S. Martins, D.R. Mazzotti, Z. Wei, Z. John Daye, M.L. Andersen, S. Tufik (2012). Whole Blood Genome-Wide Gene Expression Profile in Males after Prolonged Wakefulness and Sleep Recovery. Physiological Genomics. 44 (21): 1003-1012.

13. NJ Meyer, Z. John Daye, M Rushefski, R Aplenc, PN Lanken, MSG Shashaty, JD Christie, R Feng (2012). SNP-Set Analysis Replicates Acute Lung Injury Genetic Risk Factors. BMC Medical Genetics. 13: 52.

14. X. Jessie Jeng* and Z. John Daye* (2011). Sparse Covariance Thresholding for High-Dimensional Variable Selection. Statistica Sinica. 21 (2): 625-657. (PDF)

15. Z. John Daye^#,* and X. Jessie Jeng* (2009). Shrinkage and Model Selection with Correlated Variables via Weighted Fusion. Computational Statistics and Data Analysis. 53 (4): 1284-1298. (PDF, Technical Report 2007) (Selected as an invited student talk in the First Midwest Statistics Research Colloquium at the University of Chicago.)

Conference Abstracts

1. H. Hu, M. Nau, P. Ehrenberg, A. Chenine, Z. John Daye, Z. Wei, N. Michael, M. Vahey, J. Kim, M. Marovich, S. Ratto-Kim (2012). Distinct Gene Expression Profiles Associated with the Susceptibility of Pathogen-Specific CD4+ T Cells to HIV-1 Infection. Retrovirology. 9(2).

2. R. J. Shah, Z. John Daye, W. Lin, N. J. Meyer, J. M. Diamond, S. M. Kawut, J. Lee, D. J. Lederer, J.A. Belperio, S. Bhorade, E. J. Demissie, V. N. Lama, J. Orens, S. M. Palmer, J. Reynolds, A. Shah, P. Shah, K. M. Wille, A. Weinacker, D. S. Wilkes, L. B. Ware, D. Weill, R. Feng, J. D. Christie (2012). Variation In Oxidant Stress Genes In Recipients And Donors Is Associated With The Development Of Primary Graft Dysfunction (PGD) After Lung Transplantation. Am. J. Respir. Crit. Care Med. 185: A5325.

Book chapters

1. Z. John Daye^#,*, Kerem Ismen*, Maria P. Makabet*, Maria Misailidou*, Andres Murra*, and Sun-Ju Yook* (2005). Introduction to Financial Bubbles In Financial Bubbles, ed. S. Jutur, ICFAI University Press. (PDF)

Other Manuscripts

1. Z. John Daye (2003). Introduction to Fractional Brownian Motion in Finance. (PDF)

2. Z. John Daye and Han-Chung Lee (2000). Beyond WAP. (PDF, Slides)

Referee Services

(* multiple times)

• Statistics: Annals of Applied Statistics; Computational Statistics & Data Analysis*; Journal of Agricultural, Biological, and Environmental Statistics; Journal of the American Statistical Association*; Journal of Computational and Graphical Statistics; Journal of Multivariate Analysis; Pakistan Journal of Statistics

• Biostatistics/Bioinformatics: Bioinformatics*; Biometrics*; Biostatistics; BMC Medical Research Methodology; Pacific Symposium on Biocomputing; Statistics in Biosciences

• Machine Learning: Digital Signal Processing; Journal of Machine Learning Research

• Others: Chemometrics and Intelligent Laboratory Systems; Genetics