Research

Biological systems are highly complicated but at the same time remarkably precise and dynamic. These systems are built through well-organized self- (or assisted-) assembly processes of various biomolecules such as DNA/RNA, proteins, and lipids. These specific collections of multiple biomolecules (let’s call them biomolecular assemblages) can show distinct and often more potent activities than separated individual biomolecules.

The goals of our research group are to elucidate working principles of nature’s dynamic bio-assemblies (or assemblages) and to use these principles in various biochemical applications. Our primary strategic approach is to engineer artificial biomolecular (mostly protein) assemblies, with which many facets of bio-assemblages can be investigated.

Frequently used research techniques in our Lab are nucleic acids/protein engineering; high-order biomolecule assembling; biomolecular interaction analysis; structural analysis, cellular imaging, etc ...