Book
1. Engineering Microbial Metabolism for Chemical Synthesis: Reviews and Perspectives. Edited by Yan, Y.*, World Scientific Publishing Europe Ltd. 2017
Book Chapters
3. Yang, Y., Wang, J., Zhang, R., Yan, Y.*, Antisense RNA Elements for Downregulating Expression in Microbial Metabolic Engineering. Springer. 2019
2. Wang, J., Yang, Y., Yan, Y.*, Bioproduction of Resveratrol. in Biotechnology of Natural Products. Springer. 2018
1. Wang, J., Yan, Y.*, Glycolysis and Its Metabolic Engineering Applications. in Engineering Microbial Metabolism for Chemical Synthesis: Reviews and Perspectives. World Scientific Publishing Europe Ltd. 2017
2024
123. Lu, L., Wang, X., Wang, T., Shen, X., Sun, X., Tian, P., Yan, Y., Nielsen, J., Wang, J.*, Yuan, Q.*, A bacterial platform for producing aromatic esters from glycerol. Nature Chemical Engineering 2024; In press.
122. Gong, X., Teng, Y., Zhang, J., Gan, Q., Alaraj, A., Kner, p., Yan, Y*., Architecting a transcriptional repressor-based genetic inverter for tryptophan derived pathway regulation in Escherichia coli. Metabolic Engineering 2024; 86: 66-77
121. Xie, C., An, N., Zhou, L., Shen, X., Wang, J., Yan, Y., Sun, X.*, Yuan, Q.*, Engineering a coumarin production platform by protein and metabolic engineering. Metabolic Engineering 2024; 86: 89-98
120. Teng, Y., Gong, X., Zhang, J., Obideen, Z., Yan, Y.*, Investigating and engineering an 1,2-propanediol-responsive transcription factor-based biosensor. ACS Synthetic Biology 2024; 13:2177-2187
119. Gong, X., Zhang, J., Gan, Q., Teng, Y., Hou, J., Lyu, Y., Liu, Z., Wu, Z., Dai, R., Zou, Y., Wang, X., Zhu, D., Zhu, H., Liu, T., Yan, Y.*, Advancing microbial production through artificial intelligence-aided biology. Biotechnology Advances 2024; 74: 108399
118. Zou, Y., Teng, Y., Li, J., Yan, Y.*, Recent advances in the biosynthesis of coumarin and its derivatives. Green Chemical Engineering 2024; 5: 150-154.
117. Zou, Y., Zhang, J., Wang, J., Gong, X., Jiang, T., Yan, Y.*, A self-regulated network for dynamically balancing multiple precursors in complex biosynthetic pathways. Metabolic Engineering 2024; 82: 69-78.
116. Teng, Y., Jiang, T., Yan, Y.*, The expanded CRISPR toolbox for constructing microbial cell factories. Trends in Biotechnology 2024; 42: 104-118.
2023
115. Jiang, T., Teng, Y., Li, C., Gan, Q., Zhang, J., Zou, Y., Desai, B., Yan, Y.*, Establishing tunable genetic logic gates with versatile dynamic performance by varying regulatory parameters. ACS Synthetic Biology 2023; 12:3730-3742.
114. Gong, X., Holmes, J., Li, Y., Liu, Z., Gan, Q., Wu, Z., Zhang, J., Zou, Y., Teng, Y., Jiang, T., Zhu, H., Liu, W.*, Liu, T.*, Yan, Y*. Evaluating the potential of leading large language model in reasoning biology questions. arXiv 2023.
113. Teng, Y., Wang, J., Jiang, T., Zou, Y., Yan, Y.*, Engineering a Streptococcus Cas9 ortholog with an RxQ PAM-binding motif for PAM-free gene control in bacteria. ACS Synthetic Biology 2023; 12: 2764-2772.
112. Jiang, T., Li, C., Teng, Y., Zhang, J., Logan, D., Yan, Y.*, Dynamic metabolic control: from the perspective of regulation logic. Synthetic Biology and Engineering 2023; 1-10012.
111. Li, C., Zhou, Y., Zou, Y., Jiang, T., Gong, X., Yan, Y.*, Identifying, characterizing, and engineering a phenolic acid-responsive transcriptional factor from Bacillus amyloliquefaciens. ACS Synthetic Biology 2023; 12:2382-2392.
110. Zhang, J., Gong, X., Gan, Q., Yan, Y.*, Application of metabolite-responsive biosensors for plant natural products biosynthesis. Biosensors 2023; 13: 633.
109. Lu, L., Wang, X., Zhou, L., Liu, Q., Zhang, G., Xue, B., Hu, C., Shen, X., Sun, X., Shen, X., Yan, Y., Wang, J.*, Yuan, Q.*, Establishing biosynthetic pathway for the production of p-hydroxyacetophenone and its glucoside in Escherichia coli. Metabolic Engineering 2023; 76: 110-119.
108. An, N., Xie, C., Zhou, S., Wang, J., Sun, X., Yan, Y., Shen, X.*, Yuan, Q.*, Establishing a growth-coupled mechanism for high-yield production of β-arbutin from glycerol in Escherichia coli. Bioresource Technology 2023; 369: 128491.
107. Li, X., Li, N., Zhao, M., Zhou, Z., Li, W., Shen, X., Wang, J., Yan, Y., Sun, X.*, Yuan, Q.*, Engineering Escherichia coli native metabolism for efficient biosynthesis of orotate. Biotechnology and Bioengineering 2023; 120: 503-510.
106. Wang, J., Li, C., Jiang T., Yan, Y.*, Biosensor-assisted titratable CRISPRi high-throughput (BATCH) screening for over-production phenotypes. Metabolic Engineering 2023; 75: 58-67.
105. Wang, J., Teng, Y., Gong, X., Zhang, J., Wu, Y., Lou, L., Li, M., Xie, ZR., Yan, Y.*, Exploring and engineering PAM-diverse Streptococci Cas9 for PAM-directed bifunctional and titratable gene control in bacteria. Metabolic Engineering 2023; 75: 68-77.
2022
104. Li, W., Zhou, Z., Li, X., Ma, L., Quan, Q., Zheng, G., Liang, H., Yan, Y., Shen, X., Wang, J., Sun, X.*, Yuan, Q.*, Biosynthesis of plant hemostatic dencichine in Escherichia coli. Nature Communications 2022; 13: 5492.
103. Jiang, T., Li C., Zou, Y., Zhang, J., Gan, Q., Yan, Y.*, Establishing an Autonomous Cascaded Artificial Dynamic (AutoCAD) regulation system for improved pathway performance. Metabolic Engineering 2022; 74: 1-10.
102. Zhou, Z., Zhang, X., Wu, J., Li, X., Li, W., Sun, X., Wang, J., Yan, Y., Shen, X.*, Yuan, Q.*, Targeting cofactors regeneration in methylation and hydroxylation for high level production of ferulic acid. Metabolic Engineering 2022; 73: 247-255.
101. Gong, X., Zhang, R., Wang, J., Yan, Y.*, Engineering of a TrpR-based biosensor for altered dynamic range and ligand preference. ACS Synthetic Biology 2022; 11: 2175-2183.
100. Zhang, F., Sun, X., Shen, X., Yan, Y., Wang, J.*, Yuan, Q.*, Biosynthesis of allantoin in Escherichia coli via screening a highly effective urate oxidase. Biotechnology and Bioengineering 2022; 119: 2518-2528.
99. Wang. J., Jiang, T., Milligan, S., Zhang, J., Li, C., Yan, Y.*, Improving isoprenol production via systematic CRISPRi screening in engineered Escherichia coli. Green Chemistry 2022; 24: 6955-6964.
98. Ge, C., Yu, Z., Sheng, H., Shen, X., Sun, X., Zhang, Y., Yan, Y., Wang, J.*, Yuan, Q.*, Redesigning regulatory components of quorum-sensing system for diverse metabolic control. Nature Communications 2022; 13: 1-12.
97. Li, X., Zhao, Z., Li, W., Yan, Y., Shen, X., Wang, J., Sun, X.*, Yuan, Q.*, Design of stable and self-regulated microbial consortia for chemical synthesis. Nature Communications 2022; 13: 1-9.
96. Lu, L., Shen, X., Sun, X., Yan, Y., Yuan, Q.*, Wang, J.*, CRISPR-based metabolic engineering in non-model microorganisms. Current Opinion in Biotechnology 2022; 75: 102698.
95. Teng, Y., Zhang, J., Jiang, T., Zou, Y., Gong, X., Yan, Y.*, Biosensor-enabled pathway optimization in metabolic engineering. Current Opinion in Biotechnology 2022; 75: 102696.
94. Li, C., Zou, Y., Jiang, T., Zhang, J., Yan, Y.*, Harnessing plasmid replication mechanism to enable dynamic control of gene copy in bacteria. Metabolic Engineering 2022; 70: 67-78.
93. Li, C., Jiang, T., Li, M., Zou, Y., Yan, Y.*, Fine-tuning gene expression for improved biosynthesis of natural products: from transcription to post-translational regulation. Biotechnology Advances 2022; 54: 107853.
2021
92. Wang, J., Teng, Y., Zhang, R., Wu, Y., Lou, L., Zou, Y., Li, M., Xie, ZR., Yan, Y.*, Engineering a PAM-flexible SpdCas9 variant as a universal gene repressor. Nature Communications 2021; 12: 1-10.
91. Wang, J., Zhang, R., Zhang, J., Gong, X., Jiang, T., Sun. X., Shen, X., Wang, J., Yuan, Q., Yan, Y.*, Tunable hybrid carbon metabolism coordination for carbon-efficient biosynthesis of 1,3-butanediol in Escherichia coli. Green Chemistry 2021; 23: 8694-8706.
90. Zhang, R., Wang, J., Milligan, S., Yan, Y.*, Microbial utilization of lignin-derived aromatics via a synthetic catechol meta-cleavage pathway. Green Chemistry 2021; 23: 8238-8250.
89. Shen, X., Chen X., Wang, J., Sun, X., Dong, S., Li, Y., Yan, Y., Wang, J.*, Yuan, Q.*, Design and construction of an artificial pathway for biosynthesis of acetaminophen in Escherichia coli. Metabolic Engineering 2021; 68: 26-33.
88. Zou, Y., Li, C., Zhang, R., Jiang, T., Liu, N., Wang, J., Wang, X., Yan, Y.*, Exploring the tunability and dynamic properties of MarR-PmarO sensor system in Escherichia coli. ACS Synthetic Biology 2021; 10: 2076-2086.
87. Ning, A., Chen, X., Sheng, H., Wang, J., Sun, X., Yan, Y., Shen, X.*, Yuan, Q.*, Rewiring the microbial metabolic network for efficient utilization of mixed carbon sources. Journal of Industrial Microbiology and Biotechnology 2021; 48: kuab040.
86. Zhang, R., Zhang, Y., Wang, J., Yang, Y., Yan, Y.*, Development of antisense RNA-mediated quantifiable inhibition for metabolic regulation. Metabolic Engineering Communications 2021; e00168.
85. Sheng, H., Jing, Y., Ning, A., Shen, X., Sun, X., Yan, Y., Wang, J.*, Yuan, Q.*, Extending the shikimate pathway for microbial production of maleate from glycerol in engineered E. coli. Biotechnology and Bioengineering 2021; 118: 1840-1850.
84. Li, Y., Shen, X., Sun, X., Yuan, Q., Yan, Y., Wang, J.*, Advances of CRISPR gene editing in microbial synthetic biology. Synthetic Biology Journal 2021; 2: 106.
83. Jiang, T., Li, C., Yan, Y.*, Optimization of a p-coumaric acid biosensor system for versatile dynamic performance. ACS Synthetic Biology 2021; 10: 132-144.
2020
82. Sheng, H., Sun, X., Yan, Y., Yuan, Q., Wang, J., Shen, X.*, Metabolic engineering of microorganisms for the production of flavonoids. Frontiers in Bioengineering and Biotechnology 2020, 8: 1162.
81. Wang, J., Li, C., Zou, Y., Yan, Y.*, Bacterial synthesis of C3-C5 diols via extending amino acid catabolism. Proceedings of the National Academy of Sciences 2020; 117: 19159-19167.
80. Jiang, T., Li, C., Teng, Y., Zhang, R., Yan, Y.*, Recent advances in improving metabolic Robustness of microbial cell factories. Current Opinion of Biotechnology 2020; 66: 69-77.
79. Wang, J., Zhang, R., Chen, X., Sun, X., Yan, Y., Shen, X.*, Yuan, Q.*, Biosynthesis of aromatic polyketides in microorganisms using type II polyketide synthases. Microbial Cell Factories 2020; 19: 1-11.
78. Zhou, Z., Chen, X., Sheng, H., Shen, X., Sun, X., Yan, Y., Wang, J.*, Yuan, Q.*, Engineering probiotics as living diagnostics and therapeutics for improving human health. Microbial Cell Factories 2020; 19: 1-12.
77. Ma, L., Guo, L., Yang, Y., Guo, K., Yan, Y., Ma, X., Huo, Y.*, Protein-based biorefining driven by nitrogen-responsive transcriptional machinery. Biotechnology for Biofuels 2020; 13: 1-14.
76. Ge, C., Sheng, H., Chen, X., Shen, X., Sun, X., Yan, Y., Wang, J.*, Yuan, Q*., Quorum sensing system used as a tool in metabolic engineering. Biotechnology Journal 2020; 15: 1900360.
75. Li, C., Zhang, R., Wang, J., Wilson, L., Yan, Y.*, Protein engineering for improving and diversifying natural products biosynthesis. Trends in Biotechnology 2020; 38: 729-744.
2019
74. Yu, H., Chen, Z., Wang, N., Yu, S., Yan, Y., Huo, YX*., Engineering transcription factor BmoR for screening butanol overproducers. Metabolic Engineering 2019; 56: 28-38.
73. Wang, J., Zhang, R., Zhang, Y., Yang, Y., Lin, Y., Yan, Y.*, Developing a pyruvate-driven scenario for growth-coupled microbial production. Metabolic Engineering 2019; 55: 191-200.
72. Li, W., Ma, L., Shen, X., Wang, J., Feng, Q., Liu, L., Zheng, G., Yan, Y., Sun, X.*, Yuan, Q.*, Targeting metabolic driving and intermediate influx in lysine catabolism for high-level glutarate production. Nature Communications 2019; 10: 3337.
71. Zhang, R., Yang, Y., Wang, J., Lin, Y.*, Yan, Y.*, Synthetic symbiosis combining plasmid displacement enables rapid construction of phenotype-stable strains. Metabolic Engineering 2019; 55: 85-91.
70. Shen, X., Zhou, D., Lin, Y., Wang, J., Gao, S., Kandavelu, P., Zhang, H., Zhang, R., Wang, B-C., Rose, J.*, Yuan, Q.*, Yan, Y.*, Structural insight into catalytic versatility of the flavin-dependent hydroxylase (HpaB) from Escherichia coli. Scientific Reports 2019; 9: 7087.
69. .Shen, X., Wang, J., Li, C., Yuan, Q., Yan, Y.*, Dynamic gene expression engineering as a tool in pathway engineering. Current Opinion of Biotechnology 2019; 59: 122-129.
68. Li, X., Shen, X., Wang, J., Ri, H., Mi, C., Yan, Y., Sun, X.*, Yuan, Q.*, Efficient biosynthesis of 3,4- dihydroxyphenylacetic acid in Escherichia coli. Journal of Biotechnology 2019; 294: 14-18.
67. Li, Y., Wang, M., Zhao, Q., Shen, X., Wang, J., Yan, Y., Sun, X.*, Yuan, Q.*, Shunting phenylacetic acid catabolism for tropone biosynthesis. ACS Synthetic Biology 2019; 8: 876-883.
2018
66. Zhang, R., Li, C., Wang, J., Yan, Y.*, Microbial ligninolysis: towards a bottom-up approach for lignin upgrading. Biochemistry 2018; 58: 1501-1510.
65. Zhang, R., Li, C., Wang, J., Yang, Y., Yan, Y.*, Microbial production of small medicinal molecules and biologics: from nature to synthetic pathways. Biotechnology Advances 2018; 36: 2219-2231.
64. Huo, Y., Ren, H., Yu, H., Zhao, L., Yu, S., Yan, Y., Chen, Z., CipA-mediating enzyme self-assembly to enhance the biosynthesis of pyrogallol in Escherichia coli. Applied Microbiology and Biotechnology 2018; 1-11.
63. Yang, Y., Lin, Y., Wang, J., Wu, Y., Zhang, R., Chen, M., Shen, X., Wang, J., Chen, Z., Yuan, Q., Yan, Y.*, Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis. Nature Communications 2018; 9: 3043.
62. Wang, J., Shen, X., Wang, J., Yang, Y., Yuan, Q.*, Yan, Y.*, Exploring the promiscuity of phenol hydroxylase from Pseudomonas stutzeri OX1 for the biosynthesis of phenolic compounds. ACS Synthetic Biology 2018; 7: 1238-1243.
61. Shen, X, Wang, J., Gall, B., Ferreira, E., Yuan, Q.*, Yan, Y.*, Establishment of novel biosynthetic pathways for the production of salicyl alcohol and gentisyl alcohol in engineered Escherichia coli. ACS Synthetic Biology 2018; 7: 1012-1017.
60. LYU, Z., Chou, CW., Shi, H., Wang, L., Ghebreab, R., Phillips, D., Yan, Y., Duin, E., William, W., Assembly of methyl-coenzyme M reductase in the methanogenic archaeon Methanococcus maripaludis. Journal of Bacteriology 2018; JB. 00746-17.
59. Sekar, N., Wang, J., Zhou, Y., Fang, Y., Yan, Y., Ramasamy, R., Role of Respiratory Terminal Oxidases in the Extracellular Electron Transfer Ability of Cyanobacteria. Biotechnology and Bioengineering 2018; 115: 1361-1366.
58. Wang, J., Shen, X., Yuan, Q.*, Yan, Y*. Microbial synthesis of pyrogallol using genetically engineered Escherichia coli. Metabolic Engineering 2018; 45:134-141.
57. Wu, Y., Wang, J., Shen, X., Wang, J., Chen, Z., Sun, X., Yuan, Q.*, Yan, Y.*, Investigating the strategies for microbial production of trehalose from lignocellulosic sugars. Biotechnology and Bioengineering 2018; 115: 785-790.
56. Li, X., Chen, Z., Wu, Y., Yan, Y., Sun, X., Yuan, Q., Establishing an artificial pathway for efficient biosynthesis of hydroxytyrosol. ACS Synthetic Biology 2018; 7: 647-654.
55. Wang, J., Shen, X., Lin, Y., Chen, Z., Yang, Y., Yuan, Q.*, Yan, Y.*, Investigation of the synergetic effect of xylose metabolic pathways on the production of glutaric acid. ACS Synthetic Biology 2018; 7: 24-29.
54. Wang, J., Shen, X., Rey, J., Yuan, Q.*, Yan, Y.*, Recent Advances in Microbial Production of Aromatic Compounds and Their Derivatives. Applied Microbiology and Biotechnology 2018; 1: 47-61.
53. Wang, J., Yang, Y., Zhang, R., Shen, X., Chen, Z., Yuan, Q.*, Yan, Y.*, Microbial production of branched-chain dicarboxylate 2-methylsuccinic acid via enoate reductase- mediated bioreduction. Metabolic Engineering 2018; 45: 1-10.
2017
52. Wang, J., Mahajani, M., Jackson, S., Yang, Y., Chen, M., Ferreira, E., Lin, Y., Yan, Y.*, Engineering a bacterial platform for total biosynthesis of caffeic acid derived phenethyl esters and amides. Metabolic Engineering 2017; 44: 89-99.
51. Tian, P., Wang, J., Shen, X., Justin, R., Yuan, Q., Yan, Y.*, Fundamental CRISPR-Cas9 Tools and Current Applications in Microbial Systems. Synthetic and Systems Biotechnology 2017; 2: 219-225.
50. Wang, J., Wu, Y., Sun, X., Yuan, Q.*, Yan, Y.*, De novo Biosynthesis of Glutarate via a-Keto Acid Carbon Chain Extension and Decarboxylation Pathway in Escherichia coli. ACS Synthetic Biology 2017; 6: 1922-1930.
49. Chen, Z., Shen, X., Wang, J., Wang, J., Yuan, Q.*, Yan, Y.*, Rational Engineering of p-Hydroxybenzoate Hydroxylase to Enable Efficient Gallic Acid Synthesis via A Novel Artifical Biosynthetic Pathway. Biotechnology and Bioengineering 2017; 114: 2571-2580.
48. Chen, Z., Shen, X., Wang, J., Wang, J., Zhang, R., Rey, J., Yuan, Q.*, Yan, Y.*, Establishing an Artificial Pathway for De novo Biosynthesis of Vanillyl Alcohol in Escherichia coli. ACS Synthetic Biology 2017; 6: 1784-1792.
47. Shen, X., Mahajani, M., Wang, J., Yang, Y., Yuan, Q., Yan, Y.*, Lin, Y.*, Elevating 4-Hydroxycoumarin Production through Alleviating Thioesterase-mediated Salicoyl-CoA Degradation. Metabolic Engineering 2017; 42: 59-65.
46. Shen X., Wang, J., Wang, J., Chen, Z., Yuan, Q.*, Yan, Y.*, High-level De novo Biosynthesis of Arbutin in Engineered Escherichia coli. Metabolic Engineering 2017; 42: 52- 58.
45. Wang, J., Shen, X., Rachit, J., Wang, J., Yuan, Q.*, Yan, Y.*, Establishing A Novel Biosynthetic Pathway for the Production of 3,4-Dihydroxybutyric Acid from Xylose in Escherichia coli. Metabolic Engineering 2017; 41: 39-45.
44. Cowger, T., Yang, Y., Rink, D., Todd, T., Chen, H.*, Shen, Y., Yan, Y.*, Xie, J., Protein-Adsorbed Magnetic-Nanoparticle-Mediated Assay for Rapid Detection of Bacterial Antibiotic Resistance. Bioconjugate Chemistry 2017; 28: 890-896.
43. Wang, J., Jain, R., Shen, X., Sun, X., Cheng, M., Liao, J.C., Yuan, Q.*, & Yan, Y.*, Rational Engineering of Diol Dehydratase Enables 1,4-Butanediol Biosynthesis from Xylose. Metabolic Engineering 2017; 40: 148-156.
42. Chen, Z., Sun, X., Li, Y., Yan, Y., & Yuan, Q.*, Metabolic Engineering of Escherichia coli for Microbial Synthesis of Monolignols. Metabolic Engineering 2017; 39:102-109.
41. Wu, Y., Sun, X., Lin, Y., Shen, X., Yang, Y., Jain, R., Yuan, Q.*, & Yan, Y.*, Establishing a Synergetic Carbon Utilization Mechanism for Non-catabolic Use of Glucose in Microbial Synthesis of Trehalose. Metabolic Engineering 2017; 39:1-8.
2016
40.Lyu, Z., Jain, R., Smith, P., Fetchko, T., Yan, Y., & Whitman, W.*, Engineering the Autotroph Methanococcus maripaludis for Geraniol Production. ACS Synthetic Biology 2016; 5:577-581.
39. Sun, J., Lin, Y., Shen, X., Jain, R., Sun, X., Yuan, Q.*, & Yan, Y.*, Aerobic Biosynthesis of Hydrocinnamic Acids in Escherichia coli with A Strictly Oxygen-sensitive Enoate Reductase. Metabolic Engineering 2016; 35:75-82.
38. Wu, Y., Shen, X., Yuan, Q.*, & Yan,Y.*, Metabolic Engineering Strategies for Co-utilization of Carbon Sources in Microbes. Bioengineering 2016; 3:10.
37. Wang, J., Guleria, S., Koffas, M. A.*, & Yan, Y.*, Microbial Production of Value-added Nutraceuticals. Current Opinion in Biotechnology 2016; 37: 97-104.
36. Sekar, N., Rachit, J., Yan, Y., & Ramasamy, R.*, Enhanced Photo-bioeletrochemical Energy Conversion by Genetically Engineered Cyanobacteria. Biotechnology & Bioengineering 2016; 113:675-9.
2015
35. Sun, X., Shen, X., Jain, R., Lin, Y., Wang, J., Sun, J., Wang, J., Yan, Y.*, & Yuan, Q.*, Synthesis of Chemicals by Metabolic Engineering of Microbes. Chemical Society Reviews 2015; 44:3760-85.
34. Jain, R., Huang, Q., Yuan, Q., & Yan, Y.*, Engineering Microaerobic Metabolism of E. coli for 1,2-Propanediol Production. Journal of Industrial Microbiology & Biotechnology 2015; 42:1049-55.
33. Zhang, T., Wang, Z., Deng, L., Tan, T., Wang, F., & Yan, Y., Pull-in Urea Cycle for the Production of Fumaric Acid in Escherichia coli. Applied Microbiology and Biotechnology 2015; 99:5033-44.
32. Sun, X., Zhou, D., Kandavelu, P., Zhang, H., Yuan, Q., Wang, BC., Rose, J.*, & Yan, Y.*, Structural Insights into Substrate Specificity of Feruloyl-CoA 6'-Hydroxylase fromArabidopsis thaliana. Scientific Reports 2015; 5:10355.
31. Yang, Y., Lin, Y., Li, L., Linhardt, R., & Yan, Y.*, Regulating Malonyl-CoA Metabolism via Synthetic Antisense RNAs for Enhanced Biosynthesis of Natural Products.Metabolic Engineering 2015; 29:217-26.
30. Huang, J., Lin, Y., Yuan, Q., & Yan, Y.*, Production of tyrosine through phenylalanine hydroxylation bypasses the intrinsic feedback inhibition in Escherichia coli. Journal of Industrial Microbiology & Biotechnology 2015; 42:655-9.
29. Jain, R., Sun, X., Yuan, Q., & Yan, Y.*, Systematically Engineering Escherichia coli for Enhanced Production of 1,2-Propanediol and 1-Propanol. ACS Synthetic Biology 2015; 4:746-56.
28. Sun, X., Lin, Y., Yuan, Q.*, & Yan, Y.*, Precursor-directed biosynthesis of 5-hydroxytryptophan using metabolically engineered E. coli. ACS synthetic Biology 2015; 4:554-8.
2014
27. Lin, Y., Sun. X., Yuan, Q., & Yan, Y.*, Engineering Bacterial Phenylalanine 4-Hydroxylase for Microbial Synthesis of Human Neurotransmitter Precursor 5- Hydroxytryptophan. ACS Synthetic Biology 2014; 3:497-505.
26. Sun, X., Lin, Y., Yuan, Q., & Yan, Y.*, Biological Production of Muconic Acid via A Prokaryotic 2,3-Dihydroxybenzoic Acid Decarboxylase. ChemSusChem 2014; 7:2478-81.
25. Lin, Y., & Yan, Y.*, Biotechnological Production of Plant-Specific Hydroxylated Phenylpropanoids. Biotechnology and Bioengineering 2014; 111:1895-9.
24. Lin, Y., Sun, X., Yuan, Q., & Yan, Y.*, Extending Shikimate Pathway for the Production of Muconic Acid and Its Precursor Salicylic Acid in Escherichia coli. Metabolic Engineering 2014; 23:62-9.
23. Lin, Y., Jain, R., & Yan, Y.*, Microbial production of antioxidant food ingredients via metabolic engineering. Current Opinion of Biotechnology 2014; 26:71-78.
2013
22. Lin, Y., Shen, X., Yuan, Q., & Yan, Y.*, Microbial biosynthesis of the anticoagulant precursor 4-hydroxycoumarin. Nature Communications 2013; 4:2603.
21. Huang, Q., Lin, Y., & Yan, Y.*, Caffeic acid production enhancement by engineering a phenylalanine over-producing Escherichia coli strain. Biotechnology and Bioengineering 2013; 110:3188-96.
20. Lin, Y., Sun, X., Yuan, Q., & Yan, Y.*, Combinatorial biosynthesis of plant-specific coumarins in bacteria. Metabolic Engineering 2013; 18:69-77.
19. Sun, X., Lin, Y., Huang, Q., Yuan, Q., & Yan, Y.*, A novel muconic acid biosynthesis approach by shunting tryptophan biosynthesis via anthranilate. Applied and Environmental Microbiology 2013; 79:4024-30.
2012
18. Shen, X., Lin, Y., Jain, R., Yuan, Q., & Yan, Y.*, Inhibition of acetate accumulation leads to enhanced production of (R,R)-2,3-butanediol in Escherichia coli. Journal of Industrial Microbiology & Biotechnology 2012; 39: 1725-1729.
17. Subramanian, S., Shen, X., Yuan, Q., & Yan, Y.*, Identification and biochemical characterization of a 5-DMATS in Streptomyces coelicolor A3(2). Process Biochemistry 2012; 47: 1419-1422.
16. Lin, Y., & Yan, Y.*, Biosynthesis of caffeic acid in Escherichia coli using its endogenous hydroxylase. Microbial Cell Factories 2012; 11: 42.
2011
15. Jain, R.,& Yan, Y.*, Dehydratase mediated 1-propanol production in metabolically engineered Escherichia coli. Microbial Cell Factories 2011; 10: 97.
14. Huo, Y., Cho, K. M., Rivera, J.G. L., Monte, E., Shen, C., Yan, Y., & Liao, J.C., Conversion of proteins into biofuels by engineering nitrogen flux. Nature Biotechnology 2011; 29: 346-351.
Publications Prior to UGA
13. Yan, Y., & Liao, J.C., Enantioselective synthesis of pure (R,R)-2,3-butanediol in Escherichia coli with stereospecific secondary alcohol dehydrogenases. Organic&Biomolecular Chemistry 2009, 7:3914-3917.
12. Yan, Y., & Liao, J.C., Engineering metabolic systems for production of advanced fuels. Journal of Industrial Microbiology and Biotechnology 2009; 36(4): 471-9.
11. Leonard, E., Yan, Y., Fowler, Z.L., Li, Z., Lim, C.G., Lim, K.H., Koffas, M.A., Strain improvement of recombinant Escherichia coli for efficient production of plant flavonoids. Molecular Pharmaceutics 2008; 5(2):257-65.
10. Yan, Y., Li, Z., & Koffas, M.A., High-yield anthocyanin biosynthesis in engineered Escherichia coli. Biotechnology and Bioengineering 2008; 100(1): 126-40.
9. Leonard, E., Yan, Y., Chemler J.A., Matern U., Martens S. & Koffas M.A., Characterization of dihydroflavonol 4-reductases for recombinant plant pigment biosynthesis applications. Biocatalysis and Biotransformation 2008; 26(3): 243-51.
8. Chemler, J.A., Yan, Y., Leonard, E. & Koffas M.A., Combinatorial mutasynthesis of flavonoid analogues from acrylic acid in microorganisms. Organic Letter 2007; 9(10):1855- 8.
7. Yan, Y., Huang L., & Koffas, M.A., Biosynthesis of 5-deoxyflavanones in microorganisms. Biotechnology Journal 2007; 2(10): 1250-62.
6. Chemler, J. A., Yan, Y. & Koffas, M.A., Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. Microbial Cell Factories 2006; 5:20. (First two authors contributed equally)
5. Leonard, E., Yan, Y. & Koffas, M.A., Functional expression of a P450 flavonoid hydroxylase for the biosynthesis of plant-specific hydroxylated flavonols in Escherichia coli. Metabolic Engineering 2006; 8(2):172-81.
4. Leonard, E., Yan, Y., Lim, K.H. & Koffas, M.A., Investigation of two distinct flavone synthases for plant-specific flavone biosynthesis in Saccharomyces cerevisiae. Applied and Environmental Microbiology 2005; 71(12):8241-8.
3. Yan, Y., Kohli, A. & Koffas, M.A., Biosynthesis of natural flavanones in Saccharomyces cerevisiae. Applied and Environmental Microbiology 2005; 71(9):5610-3.
2. Yan, Y., Chemler, J., Huang, L., Martens, S. & Koffas, M.A., Metabolic engineering of anthocyanin biosynthesis in Escherichia coli. Applied and Environmental Microbiology 2005;71(7):3617-23.
1. Yan, Y., Chen, J. & Li, J., Overexpression of a small medicinal peptide from ginseng in the yeast Pichia pastoris. Protein Expression and Purification 2003; 29(2):161-6.