Publications
PEER REVIEWED PUBLICATIONS
1. Maier MLV, Siddens LK, Pennington JM, Uesugi SL, Labut E, Vertel EA, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ, Turteltaub KW, Smith JN, *Williams DE. 2023. Impact of Phenanthrene Co-Administration on the Toxicokinetics of Benzo[a]pyrene in Humans. UPLC-Accelerator Mass Spectrometry Following Oral Microdosing. Chemico-Biological Interactions. 382:110608. doi: 10.1016/j.cbi.2023.110608. PMID: 37369263.
2. Rude CI, Tidwell LG, Tilton SC, Waters KM, Anderson KA, *Tanguay RL. 2023. Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish. Toxics. 11(3). doi: 10.3390/toxics11030201. PMCID: PMC10053777.
3. Vermillion Maier ML, Siddens LK, Pennington JM, Uesugi SL, Tilton SC, Vergel EA, Anderson KA, Tidwell LG, Ognibene TJ, Turteltaub KW, Smith JN, *Williams DE. 2023. Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3’-Diindolylmethane (DIM) or Brussels sprouts. Toxicol. Appl. Pharmacol. 460:116377. doi: 10.1016/j.taap.2023.116377. PMCID: PMC9946811.
4. Rivera BN, Ghetu C, Chang Y, Truong L, Tanguay RL, Anderson KA, *Tilton SC. 2022. Leveraging multiple data streams for prioritization of mixtures for hazard characterization. Toxics: Risk Assessment on Toxicity of Chemical Mixtures. 10:651. doi: 10.3390/toxics10110651. PMCID: PMC9699527.
5. Rivera BN†, Wilson L†, Kim DN, Pande P, Anderson KA, Tilton SC, Tanguay RL. 2022. A multi-system approach to characterizing bioactivity of commonly occurring chemicals from personal passive sampling. Submitted to International Journal of Environmental Research and Public Health. doi: 10.3390/ijerph19073829. †Co-first Authors.
6. Vermillion-Maier ML, Siddens LK, Pennington JM, Uesugi SL, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ, Turtletaub KW, Smith JN, *Williams DE. 2022. Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [14C]-BaP. Environ. Int. 159:107045. doi: 10.1016/j.envint.2021.107045.
7. Chang Y, Rager JE, Tilton SC. 2021. Linking Co-regulated Gene Modules with Polycyclic Aromatic Hydrocarbon-related Cancer Risk in the 3D Human Bronchial Epithelium. Chemical Res. Toxicol. 34(6):1445-1455. doi: 10.1021/acs.chemrestox.0c00333. PMID: 34048650.
8. Vermillion-Maier ML, Siddens LK, Uesugi SL, Choi J, Leonard SW, Pennington JM, Tilton SC, Smith JN, Ho E, Chow HHS, Nguyen BD, Kolluri S, Williams DE. 2021. 3,3’-Diindolylmethane (BioResponse DIM®) Exhibits Significant Metabolism Following Oral Dosing in Humans. Drug Metabolism and Disposition. doi: 10.1124/dmd.120.000346. PMID: 34035125.
9. Chang Y, Huynh CT, Bastin KM, Rivera BN, Siddens LK, Tilton SC. 2020. Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures. Toxicology In Vitro. 69:104991. doi: 10.1016/j.tiv.2020.104991 PMCID: PMC7572825. **Highlighted by NIEHS Environmental Factor as Extramural research paper of the month.
10. Garland, MA, Geier MC, Bugel, S, Shankar, P, Brown, J, Tilton SC, Tanguay, RL. 2020. Aryl hydrocarbon receptor mediates larval zebrafish fin duplication following exposure to benzofluoranthenes. Toxicol. Sci. 176(1):46-64. doi: 10.1093/toxsci/kfaa063. PMCID: PMC7357178.
11. Chang Y, Siddens LK, Heine L, Sampson D, Zhen Y, Fisher KA, Löhr CV, Tilton SC. 2019. Comparative mechanisms of PAH toxicity by benzo[a]pyrene and dibenzo[def,p]chrysene in primary human bronchial epithelial cells cultured at air-liquid interface. Toxicology and Applied Pharmacology. 379:114644. doi: 10.1016/j.taap.2019.114644.
12. Brown J, Phillips A, Lewis D, Mans MA, Chang Y, Tanguay RL, Peterson E, Waters KM, Tilton SC. 2019. Bioinformatics Resource Manager: A systems biology web tool for miRNA and omics data integration. BMC Bioinformatics. 20:55. doi: 10.1186/s12859-019-2805-6. PMCID: PMC65525352.
13. Madeen E, Siddens LK, Uesugi S, McQuistan T, Corley RC, Smith J, Waters KM, Tilton SC, Anderson KA, Ognibene T, Turtletaub K and Williams DE. 2019. Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing. Toxicol. Applied Pharmacol. 1:364-397. doi: 10.1016/j.taap.2018.12.010.12.010. PMCID: PMC6369707.
14. Garcia GR, Shankar P, Dunham CL, Garcia A, La Du JK, Tilton SC, Tanguay RL. 2018. Signaling events downstream of AHR-activation that contribute to toxic responses: The functional role of an AHR-dependent long non-coding RNA (slincR). Enivron. Health Perspect. 126(11):117002. doi: 10.1289/EHP3281. PMCID: PMC6371766. **Highlighted by NIEHS Environmental Factor as Extramural research paper of the month.
15. Geier MC, Minick J, Truong L, Tilton S, Pande P, Anderson KA, Teeguarden J, Tanguay RL. 2018. Systematic development neurotoxicity assessment of a representative PAH Superfund mixture in the zebrafish. Toxicology Applied Pharmacol. 354:115-125. doi: 10.1016/j.taap.2018.03.029. PMCID: PMC6087484.
16. Hummel JM, Madeen EP, Siddens LK, Uesugi SL, McQuistan T, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK, Harris S, Smith J, Tilton SC, Baird WM, Williams DE. 2018. Pharmacokinetics of 14C-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction. Food Chem. Toxicol. 115:136-147. doi: 10.1016/j.fct.2018.03.003. PMCID: PMC5935529.
17. Nguyen HH, Tilton SC, Kemp CJ, Song M. 2017. Non-monotonic pathway gene expression analysis reveals oncogenic role of p27/Kip1 at intermediate dose. SAGE Cancer Informatics. 16:1176935117740132. doi: 10.1177/1176935117740132. PMCID: PMC5692148.
18. Ehrlich, AK, Pennington, JM, Tilton S, Rohlman, D, Funatake, C, Marshall, NB, Wang, X, Punj, S, O’Donnell, E, Zhen, Y, Kolluri SK, and Kerkvliet NI. 2017. AhR activation increases IL-2 production by alloresponding CD4+ T cells initiating the differentiation of mucosal-homing Tim3+Tim3+Lag3+ Tr1 cells. Eur. J. Immunology. 47(11):1989-2001. doi: 10.1002/eji.201747121. PMCID: PMC5927372.
19. Curtis LR, Bravo CF, Bayne C, Tilton F, Arkoosh M, Lambertini E, Loge F, Collier TK, Meador J, Tilton SC. 2017. Transcriptional changes in innate immunity genes in head kidneys from Aeromonas salmonicida-challenged rainbow trout fed a mixture of polycyclic aromatic hydrocarbons. Ecotoxicology and Environmental Safety. 142:157-163. doi: 10.1016/j.ecoenv.2017.03.044. PMID: 28407501.
20. Tilton SC, Markillie M, Hayes S, Taylor RC and Stenoien DL. 2016. Identification of differential gene expression patterns after acute exposure to high and low doses of low LET ionizing radiation in a reconstituted human skin tissue. Radiation Research. 186(5):531-538. doi: 10.1667/RR14471.1 PMID: 27802111. **Chosen as cover article for journal.
21. McDermott JE, Mitchell H, Gralinski LE, Eisfeld AJ, Josset L, Bankhead A, Neumann G, Tilton SC, Schafer A, Li C, Fan S, McWeeney S, Baric RS, Katze MG, Waters JM. 2016. The Effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus. BMC Syst Biol. 10(1):93. doi: 10.1186/s12918-016-0336-6. PMCID: PMC5035469.
22. Tisoncik-Go J, Gasper DJ, Kyle JE, Eisfeld AJ, Selinger C, Hatta M, Morrison J, Zink EM, Kim YM, Schepmoes AA, Purvine SO, Weitz KK, Green RR, Tilton SC, Webb-Robertson BJ, Waters KM, Metz TO, Smith RD, Kawaoka Y, Suresh M, Josset L, Katze MG. 2016. Integrated omics analysis of host responses during pandemic H1N1 influenza infection. Cell Host and Microbe. 19(2):254-266. doi: 10.1016/j.chom.2016.01.002. PMID: 26867183.
23. Hu JZ, Wang X, Feng J, Robertson BJ, Waters KM, Tilton SC, Pounds JG, Corley RA, Liu M and Hu M. 2015. Metabolite signatures in hydrophilic extracts of mouse lungs exposed to cigarette smoke revealed by 1H NMR metabolomics investigation. Metabolomics. 5:143. doi: 10.4172/2153-0769.1000143. PMCID: PMC4655886.
24. Goodale BC, La Du J, Tilton SC, Sullivan CM, Waters KM, Tanguay RL. 2015. Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs. Toxicol. Sci. 147(2):397-411. doi:10.1093/toxsci/kfv139. PMCID: PMC4612346.
25. Siddens LK, Bunde KL, Harper TA, Mcquistin TJ, Sampson DA, Lohr DV, Waters KM, Tilton SC, Krueger SK, Williams DE, Baird WM. 2015. Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse. Toxicol Appl Pharmacol. 287(2):149-160. doi:10.1016/j.taap.2015.05.019. PMCID: 4689210.
26. Tilton SC, Siddens LK, Krueger SK, Larkin AJ, Löhr CV, Williams DE, Baird WM and Waters KM. 2015. Mechanism-based classification of PAH mixtures to predict carcinogenic potential. Toxicol. Sci. 146(1):135-145. doi:10.1093/toxsci/kfv080. PMID: 25908611.
27. Cha J, Burnum-Johnson KE, Cha J, Bartos A, Li Y, Baker ES, Tilton SC, Webb-Robertson BJM, Piehowski PD, Monroe ME, Jegga A, Murata S, Hirota Y, Dey SK. 2015. Muscle segment homeobox genes direct embryonic diapause by limiting inflammation in the uterus. J Biol Chem. 290(24):15337-15349. doi:10.1074/jbc.M115.655001. PMID: 25931120.
28. Tilton SC, Matzke MM, Sowa MB, Stenoien DL, Weber TJ, Morgan WF and Waters KM. 2015. Data Integration Reveals Key Homeostatic Mechanisms Following Low Dose Radiation Exposure. Toxicol Appl Pharmacol. 285(1):1-11. doi:10.1016/j.taap.2015.01.019. PMID: 25655199.
29. Teeguarden JG, Mikheev VB, Minard KR, Forsythe WC, Wang W, Sharma G, Karin N, Tilton SC, Waters KM, Asgharian B, Price OR, Pounds JG, Thrall BD. 2014. Comparative iron oxide nanoparticle cellular dosimetry and response in mice by the inhalation and liquid cell culture exposure routes. Part Fibre Toxicol. 11(1):46. doi:10.1186/s12989-014-0046-4. PMCID: PMC4200214.
30. Aevrmann B, Pickett B, Kumar S, Klem EB, Agnihothram S, Bankhead A, Bolles M, Chang J, Carter V, Clauss TRW, Eisfeld AJ, Ellis A, Fan S, Ferris MT, Gralinski LE, Green RR, Gritsenko MA, Hatta M, Heegel RA, Jacobs JM, Jeng S, Josset L, Kelly S, Law GL, Li C, Long C, Luna ML, Matzke M, McDermott J, Menarchy V, Metz TO, Mitchell, H, Monroe ME, Neumann G, Purvine SO, Schepmoes AA, Shukla AK, Sims A, Sova P, Tchitchek N, Tilton SC, Totura A, Wang J, Webb-Robertson BJ, Wen J, Weiss JM, Yang F, Yount B, Zhang, Q, McWeeney S, Smith RD, Waters KM, Kawaoka Y, Baric R, Katze MG and Scheuermann RH. 2014. A comprehensive collection of systems biology data characterizing the host response to viral infection. Nature Scientific Data.1:140033. doi:10.1038/sdata.2014.33. [Epub ahead of print]
31. Bilal E, Sakellaropoulos T, Participants C (including Tilton SC), Melas IN, Messinis DE, Belcastro V, Rhissorrakrai K, Meyer P, Norel R, Iskandar A, Blaese E, Rice JJ, Peitsch MC, Hoeng J, Stolovitzky G, Alexopoulos LG, Poussin C. 2015. A crowd-sourcing approach for the construction of species-specific cell signaling networks. Bioinformatics. 31(4):484-491. doi:10.1093/bioinformatics/btu659. PMID: 25294919.
32. Menachery V, AJ Eisfeld, A Schafer, L Josset, AC Sims, S Proll, S Fan, C Li, G Neumann, SC Tilton, JH Chang, LE Gralinski, C Long, R Green, CM Williams, MM Matzke, BJM Webb-Robertson, AK Shukla, TO Metz, RD Smith, KM Waters, MG Katze, Y Kawaoka, and R Baric. 2014. Pathogenic influenza and coronaviruses utilize similar and contrasting approaches to control the interferon stimulated gene responses. MBio. 5(3):e01174-14. doi: 10.1128/mBio.01174-14. PMCID: PMC4030454.
33. Chen J, Tanguay RL, Tal TL, Gai Z, MA X, Bai C, Tilton SC, Jin D, Yang D, Huang C, Dong Q. 2014. Early life perfluorooctanesulphonic acid (PFOS) exposure impairs zebrafish organogenesis. Aquatic Toxicol. 150C:124-132. doi: 10.1016/j.aquatox.2014.03.005. PMCID: PMC4159678.
34. Govey PM, Jacobs JM, Tilton SC, Loiselle AE, Zhang Y, Waters KM, Karin NJ, Donahue HJ. 2014. Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways. J Biomechanics. 47(8):1838-1845. doi: 10.1016/j.jbiomech.2014.03.022. PMCID: PMC4037855.
35. Tilton SC, Karin NJ, Tolic A, Xie Y, Lai X, Hamilton RF, Waters KM, Holian A, Witzman FA, Orr G. 2014. Three human cell types respond to multi-walled carbon nanotubes and titanium dioxide nanobelts with cell-specific transcriptomic and proteomic expression patterns. Nanotoxicology. 8(5):533-48. doi: 10.3109/17435390.2013.803624. PMCID: PMC4226242
36. Franzosa JA, Bugel SM, Tal TL, La Du JK, Tilton SC, Waters KM, Tanguay RL. 2013. Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects. FASEB Journal. 27(12):4866-4876. doi: 10.1096/fj.12-225524. PMCID: PMC3834785.
37. Goodale BC, Tilton SC, Corvi MM, Wilson GR, Janszen DB, Anderson KA, Waters KM, Tanguay RL. 2013. Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish. Toxicol Appl Pharmacol. 272(3):656-670. doi: 10.1016/j.taap.2013.04.024. PMCID: PMC4098828.
38. Kodali V, Littke MH, Tilton SC, Teeguarden JG, Shi L, Frevert CW, Wang W, Pounds JG, Thrall BD. 2013. Dysregulation of macrophage activation profiles by engineered nanoparticles. ACS Nano. 7(8):6997-7010. doi: 10.1021/nn402145t. PMCID: PMC3756554.
39. Tilton SC, Karin NJ, Webb-Robertson BJM, Waters KM, Mikheev V, Lee KM, Corley RA, Pounds JG, Bigelow DJ. 2013. Impaired Transcriptional Response of the Murine Heart To Cigarette Smoke in the Setting of High Fat Diet and Obesity. Chem Res Toxicol. 26(7):1034-1042. doi: 10.1021/tx400078b. PMCID: PMC4234196.
40. Mitchell HD, Eisfeld AJ, Sims AC, McDermott JE, Matzke MM, Webb-Robertson BJM, Tilton SC, Tchitchek N, Josset L, Li C, Ellis AL, Chang JH, Heegel RA, Luna ML, Schepmos AA, Shukla AK, Metz TO, Neumann G, Benecke AG, Smith RD, Baric RS, Kawaoka Y, Katze MG, Waters KM. 2013. A Network Integration Approach to Identify Highly Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory Viruses. PLoS One. 8(7):e69374. doi:10.1371/journal.pone.0069374. PMCID: PMC3723910.
41. Tchitchek N, Eisfeld AJ, Tisoncik-Go J, Josset L, Gralinski LE, Bécavin C, Tilton SC, Webb-Robertson BJ, Metz TO, Smith RD, Waters KM, Baric R, Kawaoka Y, and Katze MG. 2013. Specific Mutations in H5N1 Mainly Impact the Magnitude and Velocity of the Transcriptomic and Proteomic Pulmonary Host Response in Mice. BMC Systems Biology. 7(1):69. doi: 10.1186/1752-0509-7-69. PMCID: PMC3750405.
42. Saili KS, Tilton SC, Waters KM, Tanguay RL. 2013. Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17β-estradiol in embryonic zebrafish. Reproductive Toxicol. 38:89-101. doi: 10.1016/j.reprotox.2013.03.009. PMCID: PMC3690774.
43. Tilton SC, Waters KM, Karin NJ, Webb-Robertson BJM, Zangar RC, Lee KM, Bigelow DJ, Pounds JG, Corley RA. 2013. Diet-Induced Obesity Reprograms the Inflammatory Response of the Murine Lung to Inhaled Endotoxin. Toxicol. Appl. Pharmacol. 267(2):137-148. doi: 10.1016/j.taap.2012.12.020. PMCID: PMC3570597.
44. Larkin A, Siddens LK, Krueger SK, Tilton SC, Waters KM, Williams DE, Baird WM. 2013. Development of a Fuzzy Neural Network Model for Predicting Polycyclic Aromatic Hydrocarbon-Mediated Perturbations of the Cyp1b1 Transcriptional Regulatory Network in Mouse Skin. Toxicol. Appl. Pharmacol. 267(2):192-199. doi: 10.1016/j.taap.2012.12.011. PMCID: PMC3626406.
45. Sims AC*, Tilton SC*, Menarchy VD, Gralinski LE, Matzke MM, Webb-Robertson BJM, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR, Burkett SE, Zornetzer G, Tseng CTK, Metz TO, Pickles R, McWeeney S, Smith RD, Katze MG, Waters KM, Baric RS. 2013. Release of SARS-CoV Nuclear Import Block Enhances Host Transcription in Human Lung Cells. J. Virology. 87(7):3885-902. doi: 10.1128/JVI.02520-12. PMCID: PMC3624188. *Co-first authors.
46. Truong L, Tilton SC, Zaikova T, Richman E, Waters KM, Hutchison JE, Tanguay RL. 2013. Surface functionalities of gold nanoparticles impact embryonic gene expression responses. Nanotoxicology. 7(2):192-201. 10.3109/17435390.2011.648225. PMCID: PMC3399027.
47. Tilton SC, Tal TL, Scroggins SM, Franzosa JA, Peterson ES, Tanguay RL and Waters KM. 2012. Bioinformatics Resource Manager v2.3: An integrated software environment for systems biology with microRNA and cross-species analysis tools. BMC Bioinformatics. 13:311. doi: 10.1186/1471-2105-13-311. PMCID: PMC3534564.
48. Chen J, Huang C, Truong L, La Du J, Tilton SC, Waters KM, Lin K, Tanguay RL and Dong Q. 2012. Early life stage trimethyltin exposure induces ADP-ribosylation factor expression and perturbs the vascular system in zebrafish. Toxicology. 302(2-3):129-139. doi: 10.1016/j.tox.2012.09.004. PMCID: PMC3511642.
49. Siddens LK, Larkin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, Pereira CB, Lohr CV, Arlt VM, Phillips DH, Williams DE, Baird WM. 2012. Polycyclic aromatic hydrocarbons as skin carcinogens: Comparisons of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicology and Applied Pharmacology. 264(3):377-386. doi: 10.1016/j.taap.2012.08.014. PMCID: PMC3483092.
50. von Neubeck C, Shankaran H, Karin NJ, Kauer PM, Chrisler WB, Wang X, Robinson RJ, Waters KM, Tilton SC, Sowa MB. 2012. Cell type-dependent gene transcription profile in a three-dimensional human skin tissue model exposed to low doses of ionizing radiation: Implications for medical exposures. Environ Mol Mutagen. 53(4):247-59. doi: 10.1002/em.21682. PMID: 22351304.
51. Tal TL, Franzosa JA, Tilton SC, Philbrick KA, Iwaniec UT, Turner RT, Waters KM, Tanguay RL. 2012. MicroRNAs control neurobehavioral development and function in zebrafish. FASEB J. 26(4):1452-61. doi: 10.1096/fj.11-194464. PMCID: PMC3316906.
52. Tilton F, Tilton SC, Bammler TK, Beyer RP, Stapleton PL, Scholz NL and Gallagher EP. 2011. Transcriptional impact of organophosphate and metal mixtures on olfaction: copper dominates the chlorpyrofos-induced response in adult zebrafish. Aquatic Toxicol. 102(3-4):205-215. doi: 10.1016/j.aquatox.2011.01.012. PMCID: PMC3991301.
53. McDermott JE, Costa M, Janszen D, Singhal M and Tilton SC. 2010. Separating the drivers from the driven: Integrative network and pathway approaches aid in identification of disease biomarkers from high-throughput data. Dis. Markers. 28(4):253-266. doi: 10.3233/DMA-2010-0695. PMCID: PMC3833603.
54. Williams DE, Orner G, Willard KD, Tilton S, Hendricks JD, Pereira C, Benninghoff AD and Bailey GS. 2009. Rainbow Trout (Oncorhynchus mykiss) and Ultra-Low Dose Cancer Studies. Comp. Biochem. Physiol. C. 149:175-181. doi: 10.1016/j.cbpc.2008.12.002. PMCID: PMC2895404.
55. Browne EP, Stapleton HM, Kelly SM, Tilton SC and Gallagher EP. 2009. In vitro hepatic metabolism of 2,2’,4,4’,5-pentabromodephyl ether (BDE 99) in Chinook salmon (Onchorhychus tshawytscha). Aquatic Toxicol. 42(24):9404-9411. doi: 10.1016/j.aquatox.2009.02.017. PMCID: PMC2739728.
56. Lefebvre KA, Tilton SC, Bammler TK, Beyer RP, Srinouanprachan S, Stapleton PL, Farin FM, and Gallagher EP. 2009. Gene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses. Toxicol. Sci. 107(1):65-77. doi: 10.1093/toxsci/kfn207. PMCID: PMC2735419.
57. Tilton SC, Orner GA, Benninghoff AD, Carpenter HM, Hendricks JD, Pereira CB and Williams DE. 2008. Genomic profiling reveals an estrogenic mechanism for hepatic tumor promotion by PFOA. Environ. Health Perspect. 116(8):1047-1055. doi: 10.1289/ehp.11190. PMCID: PMC2516568.
58. Tilton F, Tilton SC, Bammler TK, Beyer R, Farin F, Stapleton PL and Gallagher EP. 2008. Transcriptional biomarkers and mechanisms of copper-induced olfactory injury in zebrafish. Environ. Sci. Technol. 42(24):9404-9411. PMCID: PMC3321378.
59. Tilton SC, Hendricks JD, Orner GA, Pereira CB, Bailey GS and Williams DE. 2007. Gene expression analysis during tumor enhancement by the dietary phytochemical, 3,3’-diindolylmethane, in rainbow trout. Carcinogenesis. 28(7):1589-1598. PMID: 17272308.
60. Tilton SC, Givan SA, Pereira C, Bailey GS and Williams DE. 2006. Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17β-estradiol and β-naphthoflavone in rainbow trout. Toxicol. Sci. 90:61-72. PMID: 16192472.
61. Tilton SC, Gerwick, LG, Hendricks JD, Rosato CS, Corley-Smith G, Givan SA, Bailey GS, Bayne CJ and Williams DE. 2005. Use of a rainbow trout oligonucleotide microarray to examine transcriptional patterns in aflatoxin B1-induced hepatocellular carcinoma compared to adjacent liver. Toxicol. Sci. 88(2):319-330. PMID: 16141433.
62. Tilton SC, Foran CM and Benson WH. 2005. Relationship between ethinylestradiol-mediated changes in endocrine function and reproductive impairment in Japanese medaka (Oryzias latipes). Environ. Toxicol. Chem. 24(2):352-359. PMID: 15719995.
63. Tilton SC, Foran CM and Benson WH. 2003. Effects of cadmium on the reproductive axis of Japanese medaka (Oryzias latipes). Comp. Biochem. Physiol. C. 136:265-276. PMID: 14659460.
64. Thompson SC, Tilton, F, Schlenk DK, and Benson WH. 2000. Comparative vitellogenic responses in three teleost species: Extrapolation to in situ field studies. Mar. Environ. Res. 51:185-189. PMID: 11460689.
BOOK CHAPTERS
1. Mahadevan B, Baisch B, Tilton SC, Hayes AW. 2023. Chapter 5: Chemical Contaminants in Food. In History of Food and Nutrition Toxicology. Eds E. Haugabrooks and A.W. Hayes. Elsevier Inc., pp. 103-122.
2. Walter RB, Timmins GS, Tilton SC, Orner GA, Benninghoff AD, Bailey GS and Williams DE. 2008. Carcinogenesis models: focus on xiphophorus and rainbow trout. In Oceans and Human Health: Risks and Remedies from the Seas. Eds., P Walsh, H Solo-Gabriele, LE Fleming, SL Smith and WH Gerwick, Elsevier Inc., pp. 585-612.
3. Degitz SJ, Hoke RA, Bradbury S, Brennan R, Ferguson L, Klaper R, Orban L, Spurgeon D and Tilton S. 2007. Application of Genomics to Regulatory Ecological Risk Assessments for Pesticides. In Genomics in Regulatory Ecotoxicology: Applications and Challenges. Eds., GT Ankley, GP Daston, A Miracle and EJ Perkins, CRC Press, pp. 63-86.
4. IARC Working Group on the Evaluation of Cancer Preventive Strategies. Chapter 3: Metabolism, kinetics and genetic variation. In IARC Handbooks of Cancer Prevention: Cruciferous Vegetables, Isothiocyanates and Indoles, Vol. 9, IARC Press, Lyon, France, 2004. Contributing author.
SOFTWARE RELEASES
Bioinformatics Resource Manager (BRM) Web Tool version 2.0. Software development team: Katrina Waters, Susan Tilton, Elena Peterson, Aaron Phillips, Joe Brown. Released March 2017. (http://cbb.pnnl.gov/brm/)
Bioinformatics Resource Manager (BRM) v2.3. Software development team: Katrina Waters, Susan Tilton, Elena Peterson, Tara Gibson, Markus Kobold, Sheena Scroggins. Released March 2012.
Bioinformatics Resource Manager (BRM) web version. Software development team: Katrina Waters, Susan Tilton, Elena Peterson, Markus Kobold, Aaron Phillips. Released March 2015. (http://cbb.pnnl.gov/brm/)