Welcome to the WLLab!

Our research interest is to understand the neural basis of developmental disorders. Using molecular, cellular, physiological, and behavioral approaches in mouse models of disease, we aim to identify the neural substrates underlying pathogenesis of autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD), Rett syndrome (RTT), and CDKL5 deficiency disorder (CDD). Currently, our main projects focus on exploring the roles of methyl-CpG binding protein 2 and cyclin-dependent kinase-like 5 in psychomotor control and early-onset epilepsy in normal and diseased brains. Possible therapeutics by genetic, cellular, pharmacological or bioelectrical approaches are continuously being tested in mice.