Dr. Thanos (Athanasios) Manos

Since September 1st, 2014, I am working as a “Scientific researcher” at the: Institute of Neuroscience and Medicine (INM-7), Forschungszentrum Jülich, Germany. (click here for my INM-7 personal homepage)

One of my main research goal is the optimization of stimulation protocols (e.g. the Coordinated Reset stimulation) for counteracting abnormal neuronal synchrony. Such an abnormally strong neuronal synchronization is found in a number of brain disorders, e.g. in Parkinson’s disease, tinnitus etc. For this purpose, I use mathematical modeling which incorporates synaptic/structural plasticity as well as dynamic self-organization principles of the nervous system. The ultimate goal is to induce long-lasting desynchronizing effects that persist cessation of stimulation.

Currently, I am extending my research focus in implementing whole brain dynamical models with more realistic large-scale connectivity. To this end, I am using fMRI based neuroimaging and the analyses of inter-individual variability of neuronal dynamics in larger populations. The goal here is to Investigate the impact of several disease states (e.g. Parkinson’s disease) as well as aging in resting states brain activity and functional connectivity dynamics.

My main research interests include:

  • Mathematical Modeling of Biological Systems, Neuromodulation and Whole Brain Dynamical Modeling
  • Modeling and simulation of neuroimaging data
  • Nonlinear Ordinary and Partial Differential Equations - Numerical integration methods
  • Hamiltonian and Dissipative Dynamical Systems - Integrability
  • Classical & Quantum Chaos, Chaos detection techniques
  • Lattice Dynamics and Localization, Systems with Long Range Interactions
  • Regular and Chaotic motion in Galactic Dynamics
  • Granular Matter and Collective behaviour in Traffic Systems

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