Publications

 Peer-review Journal Publication

1. 1.   Huang WY, Liang NW, Kuan CH, Yu LJ, Wu TC, Chang CW, Wang TW*. Hybrid Apoptotic Body Decorated Supramolecular Hydrogel System for Melanoma Cancer Immunoediting. Chemical Engineering Journal 2025; 526 :171086 (PDF)

   2.     Kuan CH#, Wang YN#, Liao EF, Wang WH, Kung PJ, Huang WY, Chen SH, Chen SH6, Hu JJ, Lin SJ, Wang TW*. Viscoelastic Hydrogel with Mechanomodulatory Tension Shielding and Time-Dependent Immunomodulatory Effects for Scarless Healing. Advanced Healthcare Materials 2025:e01954 (PDF)

   3.   Chen DC, Hwang CW, Chang CY, Kuo CL, Chen HL, Lan PH, Tsai MT, Wang TW, Wan D*.  Superdurable, Flexible Ceramic Nanofibers for Sustainable Passive Radiative Cooling. ACS Nano 2025;19(31):28280-28294

   4.   Yang SW, Liao MF, Wang TW, Hung YH, Lee YL, Dang QT, Chen PY, Ro LS, Hu YC*. Neuropathic pain attenuation by adipose-derived stem cells engineered with RNA-guided gene activation. Journal of the Taiwan Institute of Chemical Engineers 2025; 176: 106304

   5.   Kuan CH*, Chang L, Ho CY, Tsai CH, Liu YC, Huang WY, Wang YN, Wang WH, Wang TW*.  Immunomodulatory hydrogel orchestrates pro-regenerative response of macrophages and angiogenesis for chronic wound healing. Biomaterials 2025; 314: 122848 (PDF)

   6.   Lan P., Huang C., Chen T., Wang TW, Chen H*, Wan D*. Hierarchical Ceramic Nanofibrous Aerogels for Universal Passive Radiative Cooling. Advanced Functional Materials 2024; 52:2410285

   7.   Fu WY, Chiu YL, Huang SC, Huang WY, Hsu FT, Lee HY, Wang TW, Keng PY*. Boron Neutron Capture Therapy Enhanced by Boronate Ester Polymer Micelles: Synthesis, Stability, and Tumor Inhibition Studies. Biomacromolecules 2024 ;25(7):4215-4232.

   8.   Chiu YL, Fu WY, Huang WY, Hsu FT, Chen HW, Wang TW, Keng PY*. Enhancing Cancer Therapy: Boron-Rich Polyboronate Ester Micelles for Synergistic BNCT and PD-1/PD-L1 Checkpoint Blockade. Biomaterials Research 2024;28:0040. DOI: 10.34133/bmr.0040  

   9.   Tsen HT, Sun TC, Lai TK, Huang WY, Wang HC, Lu TT, Wang TW*. Cisplatin-activated and Hemoglobin-mediated Injectable Hydrogel System for Antitumor Chemodynamic and Chemotherapy. Biomedicine & Pharmacotherapy 2024; 175: 116713 (PDF)

   10.   Yang CJ, Huang WL, Yang Y, Kuan CH, Tseng CL, Wang TW.* Zwitterionic Modified and Freeze-thaw Reinforced Foldable Hydrogel as Intraocular Lens for Posterior Capsule Opacification Prevention. Biomaterials 2024; 309: 122593 (PDF)

   11.   Liu YC, Chen SH, Kuan CH, Chen SH, Huang WY, Chen HX, Wang TW*. Assembly of Interfacial Polyelectrolyte Complexation Fibers with Mineralization Gradient for Physiologically-inspired Ligament Regeneration. Advanced Materials. 2024 ;36(25):e2314294 (PDF)

   12.   Lee CH, Huang WY, Lee KY, Kuan CH, Wu TC, Sun JS, Wang TW*. Bioinspired Adhesive Nanofibrous Hydrogel Promotes Immune Infiltration through Effective Immunochemotherapy for Osteosarcoma Treatment. Chemical Engineering Journal 2024; 486 :150236 (PDF)

   13.   Su YC, Phan TTT, Wang TW, Chang SH, Lin FH, Hsu TS, Lin LY*. Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation. Frontiers in Bioengineering and Biotechnology 2023;11:1236429

   14.   Chien YC, Hsu YT, Chiang CW, Keng PY*, Wang TW. Investigating the electrostatic complexation of BCNO nanoparticles with a stimuli-responsive double hydrophilic graft copolymer. Giant 2023;14,100162

   15.   Lan KW, Huang WY, Chiu YL, Hsu FT, Chien YC, Hsiau YY, Wang TW, Keng PY*. In vivo investigation of boron-rich nanodrugs for treating triple-negative breast cancers via boron neutron capture therapy. Biomaterials Advances 2023;155:213699.

   16.   Chen LH, Liang NW, Huang WY, Liu YC, Ho CY, Kuan CH, Huang YF, Wang TW*. Supramolecular Hydrogel for Programmable Delivery of Therapeutics to Cancer Multidrug Resistance. Biomaterials Advances (Materials Science & Engineering C-Materials for Biological Applications) 2023 ;146: 213282 (PDF)

   17.   Ho CY, Wang CC, Wu TC, Kuan CH, Liu YC, Wang TW*. Peptide-functionalized Double Network Hydrogel with Compressible Shape Memory Effect for Intervertebral Disc Regeneration. Bioengineering & Translational Medicine 2022: e10447 (PDF)

   18.   Hsieh PH, Huang WY, Wang HC, Kuan CH, Shiue TY, Chen Y, Wang TW*. Dual-responsive Polypeptide Nanoparticles Attenuate Tumor-associated Stromal Desmoplasia and Anticancer through Programming Dissociation. Biomaterials 2022; 284:121469 (PDF)

   19.   Chiang CW, Chien YC, Yu WJ, Ho CY, Wang CY, Wang TW, Chiang CS, Keng PY*. Polymer-Coated Nanoparticles for Therapeutic and Diagnostic Non-10B Enriched Polymer-Coated Boron Carbon Oxynitride (BCNO) Nanoparticles as Potent BNCT Drug. Nanomaterials 2021, 11, 2936.

   20.   Le Kim TH, Koo BI, Jo SD, Liang NW, Yang MY, Cho I, Chang JB, Wang TW, Nam YS *. Artificial Taste Buds: Bioorthogonally Ligated Gustatory-Neuronal Multicellular Hybrids Enabling Intercellular Taste Signal Transmission. ACS Biomaterials Science & Engineering 2021;7(8):3783-3792.

   21.   Chao KY, Huang WY, Ho CY, Wan D, Wang HC, Yang CY, Wang TW*. Biodegradable Aniline-derived Electroconductive Film for the Regulation of Neural Stem Cells Fate. Journal of Materials Chemistry B 2021, 9, 1325 - 1335 (PDF)

   22.   Yang CY, Huang WY, Chen LH, Liang NW, Wang HC, Lu J, Wang X, Wang TW*. Neural Tissue Engineering: The Influence of Scaffold Surface Topography and Extracellular Matrix Microenvironment. Journal of Materials Chemistry B 2021, 9, 567 - 584 (PDF)

   23.   Huang LC, Wang HC, Chen LH, Ho CY, Hsieh PH, Huang MY, Wu HC, Wang TW*.Bioinspired Self-assembling Peptide Hydrogel with Proteoglycan-assisted Growth Factor Delivery for Therapeutic Angiogenesis. Theranostics  2019: 9(23); 7072-7087 (IF: 8.063, N/M: 1/111) (PDF)

   24.   Jian WH, Wang HC, Kuan CH, Chen MH, Wu HC, Sun JS, Wang TW*. Glycosaminoglycan-based hybrid hydrogel encapsulated with polyelectrolyte complex nanoparticles for endogenous stem cell regulation in central nervous system regeneration. Biomaterials 2018: 174; 17-30 (IF: 10.273, N/M: 4/107) (PDF)

   25. Wang TW*, Chang KC, Chen LH, Liao SY, Yeh CW, Chuang YJ. Effects of an injectable functionalized self-assembling nanopeptide hydrogel on angiogenesis and neurogenesis for regeneration of the central nervous system. Nanoscale 2017: 9; 16281 – 16292 (IF: 7.367, N/M: 23/275) (PDF)

   26.   Chang YC, Chen MH, Liao SY, Wu HC, Kuan CH, Sun JS, Wang TW*. Multi-channeled Nerve Guidance Conduit with Spatial Gradients of Neurotrophic Factors and Oriented Nanotopography for Repairing the Peripheral Nervous System. ACS Appl. Mater. Interfaces 2017: 9(43); 37623-37636. (IF: 7.504, N/M:22/275) (PDF)

   27.   Lee YH, Wu HC, Yeh CW, Kuan CH, Liao HT, Hsu HC, Tsai JC, Sun JS*, Wang TW*. Enzyme-crosslinked gene-activated matrix for the induction of mesenchymal stem cells in osteochondral tissue regeneration. Acta Biomaterialia 2017: 63; 210-226 (IF: 6.319, N/M: 3/77) (PDF)

   28.   Wang TW*, Yeh CW, Kuan CH, Wang LW, Chen LH, Wu HC, Sun JS. Tailored design of multifunctional and programmable pH-responsive self-assembling polypeptides as drug delivery nanocarrier for cancer therapy. Acta Biomaterialia 2017:58; 54-66 (IF: 6.319, N/M: 3/77) (PDF)

   29.   Yeh CW, Wang LW, Wu HC, Hsieh YK, Wang J, Chen MH, Wang TW*. Development of biomimetic micro-patterned device incorporated with neurotrophic gradient and supportive Schwann cells for the applications in neural tissue engineering. Biofabrication. 2017: 9(1); 015024 (IF: 5.240, N/M: 5/77) (PDF)

   30.   Wu HC*, Wang TW, Sun JS, Lee YH, Shen MH, Tsai ZR, Chen CY, Hsu HC. Development and Characterization of a Bioinspired Bone Matrix with Aligned Nanocrystalline Hydroxyapatite on Collagen Nanofibers. Materials 2016, 9(3), 198 (IF: 2.654, N/M: 82/275) (PDF)

   31.   Lin CJ, Kuan CH, Wang LW, Wu HC, Chen Y, Chang CW, Huang RY, Wang TW*. Integrated self-assembling drug delivery system possessing dual responsive and active targeting for orthotopic ovarian cancer theranostics. Biomaterials 2016;90:12-26 (IF: 8.402, N/M: 2/77) (PDF)

   32.   Wu YF, Wu HC, Kuan CH, Lin CJ, Wang LW, Chang CW, Wang TW*. Multi-functionalized carbon dots as theranostic nanoagent for gene delivery in lung cancer therapy. Scientific Reports 2016:6:21170 (IF: 4.259, N/M: 10/64) (PDF)

   33.   Wu HC*, Wang TW, Hsieh SY, Sun JS, Kang PL. Targeted Delivery of Hyaluronan-Immobilized Magnetic Ceramic Nanocrystals. Journal of Biomedical Nanotechnology 2016:12(1): 103-113 (IF: 4.675, N/M: 7/33) (PDF)

   34.   Lai HJ, Kuan CH, Wu HC, Tsai JC, Chen TM, Hsieh DJ, Wang TW*. Tailored design of electrospun composite nanofibers with staged release of multiple angiogenic growth factors for chronic wound healing. Acta Biomaterialia 2014;10(10):4156-4166 (IF: 6.319, N/M: 3/77) (PDF)

   35.   Hsiao HM*, Lin CH, Liao YC, Chen HY, Wang TW. Hemodynamic Behavior of Coronary Stents in Straight and Curved Arteries. Current Nanoscience 2014:10(2):205-211 (PDF)

   36.   Yang CS, Wu HC, Sun JS, Hsiao HM, Wang TW*. Thermo-induced shape-memory PEG-PCL copolymer as a dual-drug-eluting biodegradable stent. ACS Appl. Mater. Interfaces 2013: 5 (21), 10985–10994 (IF: 7.504, N/M:22/275) (PDF)

   37.   Yeh PH, Sun JS, Wu HC, Hwang LH, Wang TW*. Stimuli-responsive HA-PEI nanoparticles encapsulating endostatin plasmid for stem cell gene therapy. RSC Advances 2013; 3 (31): 12922 – 12932 (IF: 3.108, N/M: 59/166) (PDF)

   38.   Chen YY, Wu HC, Sun JS, Dong GC, Wang TW*. Injectable and thermoresponsive self-assembled nanocomposite hydrogel for long-term anticancer drug delivery. Langmuir 2013;29(11):3721-3729 (IF: 3.833, N/M: 53/275) (PDF)

   39.   Cheng TY, Wu HC, Chang WH, Huang MY, Lee CH, Wang TW*. Self-assembling functionalized nanopeptides for immediate hemostasis and accelerative liver tissue regeneration. Nanoscale 2013; 5 (7): 2734 – 2744 (IF: 7.367, N/M: 23/275) (PDF)

   40.   Chang YJ, Tsai CJ, Tseng FG, Chen TJ, Wang TW*. Micropatterned stretching system for the investigation of mechanical tension on neural stem cells behavior. Nanomedicine: Nanotechnology, Biology, and Medicine 2013;9:345-355 (IF: 5.720, N/M: 11/128) (PDF)

   41.   Cheng TY, Chen MH, Chang WH, Huang MY, Wang TW*. Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering. Biomaterials 2013; 34(8):2005-2016 (IF: 8.402, N/M: 2/77) (PDF)

   42.   Goh JH, Wu HC, Chen MH, Chen MY, Chang SC, Wang TW*. Control of three-dimensional substrate stiffness to manipulate mesenchymal stem cell fate toward neuronal or glial lineages. Acta Biomaterialia 2013;9(2):5170-5180 (IF: 6.319, N/M: 3/77) (PDF)

   43.   Huang YJ, Wu HC, Tai NH, Wang TW*. Carbon nanotube rope with electrical stimulation promotes the differentiation and maturity of neural stem cells. Small 2012;8(18): 2869–2877  (IF: 8.643, N/M: 20/275) (PDF)

   44.   Wu HC, Tsai ZR, Wang TW, Sun JS, Shen MH, Wang YC. Characterization of enzymatic crosslinked hydroxyapatite/collagen nanocomposite for bone tissue engineering. Journal of Tissue Engineering and Regenerative Medicine 2012; 6(S1): 196-197 (IF: 3.989, N/M: 8/77)

   45.   Yeh PH, Wu HC, Sun JS, Wang TW*. Development of disulfide-modified hyaluronan graft polyethyleneimine nanocarrier for gene transfection. Journal of Tissue Engineering and Regenerative Medicine 2012; 6(S1): 288 (IF: 3.989, N/M: 8/77)

   46.   Wu HC, Wang TW, Lin FH, Sun JS*. Characterization of Magnetic Hydroxyapatite Nanocrystallites and Potential Application for MRI Contrast Agent. Current Nanoscience 2011;7:902-907 (PDF)

   47.   Wu HC, Wang TW, Bohn MC, Lin FH, Spector M*. Novel Magnetic Hydroxyapatite Nanoparticles as Non-viral Vectors for the Glial Cell-line Derived Neurotrophic Factor Gene. Advanced Functional Materials 2010;20(1):67-77  (IF: 12.124, N/M: 12/271) (PDF)

   48.   Wang TW, Spector M*. Development of hyaluronic acid-based scaffolds for brain tissue engineering. Acta Biomaterialia. 2009:5(7):2371-2384 (IF: 6.319, N/M: 3/77) (PDF)

   49.   Wang TW, Wu HC, Wang HY, Lin FH*, Sun JS*. Regulation of Adult Human Mesenchymal Stem Cells into Osteogenic and Chondrogenic Lineages by Different Bioreactor System. Journal of Biomedical Materials Research Part A. 2009;88(4):935-46  (IF: 3.076, N/M: 21/77) (PDF)

   50.   Wang TW, Lu HY, Lou PJ, Lin FH*. Application of Highly Sensitive, Modified Glass Substrate based Immuno-PCR on the Early Detection of Nasopharyngeal Carcinoma. Biomaterials. 2008;29(33)4447-54  (IF: 8.402, N/M: 2/77) (PDF)

   51.   Tseng CL, Wang TW, Dong GC, Wu YH, Lin FH*. Development of gelatin nanoparticles with biotinylated EGF conjugation for lung cancer targeting.  Biomaterials. 2007:28(27):3996-4005 (IF: 8.402, N/M: 2/77)  (PDF)

   52.   Wang TW, Wu HC, Wang WR, Lin FH*, Lou PJ, Shieh MJ, Young TH. The Development of Magnetic Degradable DP-Bioglass for Hyperthermia Cancer Therapy.  Journal of Biomedical Materials Research Part A.2007;83(3):828-837  (IF: 3.076, N/M: 21/77) (PDF)

   53. Wu HC, Wang TW, Sun JS, Wang WH, Lin FH*. A Novel Biomagnetic Nanoparticle Based on Hydroxyapatite. Nanotechnology.2007;18:165601 (IF: 3.440, N/M: 27/147) (PDF)

   54. Wang TW, Sun JS, Wu HC, Lin FH*. Evaluation and Biological Characterization of Bi-layer Gelatin/Chondroitin-6-Sulphate/Hyaluronic Acid Membrane. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2007:82(2):390-9 (IF: 3.189, N/M: 19/77) (PDF)

   55. Wu HC, Wang TW, Kang PL,Tsuang YH, Sun JS*, Lin FH*. Coculture of Endothelial and Smooth Muscle Cells on a Collagen Membrane in the Development of a Small-diameter Vascular Graft. Biomaterials.2007;28(7):1385-1392   (IF: 8.402, N/M: 2/77) (PDF)

   56. Wang TW, Wu HC, Sun JS, Lin FH*. Real-time PCR Quantification of Protein Expression in Skin Equivalent Monoculture and Coculture Model. Advanced Materials Research. 2007; 15-17: 95-100

   57.   Wu HC, Wang TW, Sun JS, Lin FH*. Tissue Engineering of Vascular Graft. Advanced Materials Research. 2007; 15-17: 101-106

   58.   Wang TW, Wu HC, Huang YC, Sun JS, Lin FH*. The Effect of the Self-designed Bifunctional RGD-containing Fusion Protein on the Behavior of Human Keratiocytes and Dermal Fibroblasts. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2006 ;79(2):379-87  (IF: 3.189, N/M: 19/77) (PDF)

   59.   Wang TW, Sun JS, Wu HC, Tsuang YH, Wang WH, Lin FH*. The Effect of Gelatin-Chondroitin Sulphate-Hyaluronic Acid Skin Substitute on Wound Healing in SCID Mice. Biomaterials. 2006 ; 27(33):5689-97  (IF: 8.402, N/M: 2/77) (PDF)

   60.   Wang TW, Sun JS, Huang YC, Wu HC, Chen LT, Lin FH*. Skin Basement Membrane and Extracellular Matrix Proteins Characterization and Quantification by Real Time RT-PCR. Biomaterials. 2006;27(29):5059-5068  (IF: 8.402, N/M: 2/77)  (PDF)

   61.   Wang TW, Wu HC, Huang YC, Sun JS, Lin FH*. Biomimetic Bi-layered Gelatin-Chondroitin 6 Sulphate-Hyaluronic Acid Biopolymer as the Scaffold for Skin Equivalent Tissue Engineering. Artificial Organs. 2006;30(3):141-149 (IF: 2.403, N/M: 28/77)  (PDF)

   62.   Huang YC, Wang TW, Sun JS, Lin FH*. Investigation of Mitomycin-C-treated Fibroblasts in 3-D Collagen Gel and Conditioned Medium for Keratinocyte Proliferation. Artificial Organs. 2006;30(3):150-159 (IF: 2.403, N/M: 28/77) (PDF)

   63.   Wang TW, Wu HC, Huang YC, Sun JS, Lin FH*. Preparation and Evaluation of GAG-incorporated Skin Substitute: An In Vitro Study. Biomedical Engineering-Applications, Basis & Communications. 2006;18:153-157 (PDF)

   64.   Huang YC, Wang TW, Sun JS, Lin FH*. Effect of Calcium Ion Concentration on Keratinocyte Behaviors in the Defined Media. Biomedical Engineering-Applications, Basis & Communications. 2006;18:37-41 (PDF)

   65. Huang YC, Wang TW, Sun JS, Lin FH*. Epidermal morphogenesis in an in-vitro model using a fibroblasts-embedded collagen scaffold. Journal of Biomedical Science. 2005;12(6):855-867 (IF: 2.799, N/M: 51/128) (PDF)

   66.   Wang TW, Huang YC, Sun JS, Lin FH*. Organotypic Keratinocyte-fibroblast Cocultures on a Bilayer Gelatin Scaffold as a Model of Skin Equivalent. Biomedical Sciences Instrumentation. 2003;39: 523-528

   67.   Huang YC, Wang TW, Sun JS, Lin FH*. Cultured Keratinocytes and Dermal Fibroblasts on a Double-layer Scaffold with Bi-medium Culture System. Biomedical Sciences Instrumentation. 2003;39: 500-505

Patent

1. Wang LW, Wang TW. SEQUENTIALLY DECOMPOSABLE POLYPEPTIDE-BASED NANOCARRIERS WITH PROTECTIVE SHELL AND PREPARATION THEREOF. US Patent US 10,905,653 (2021.02.02~2038.08.31)

2. WH Jian, Wang TW. HYBRID HYDROGEL AND METHOD OF FABRICATING THE SAME. US Patent US 10,772,844 B2 (2020.09.15~2038.11.05)

3. WH Jian, Wang TW. 複合水膠及其製備方法 Taiwan Patent 690332 (2020.04.11~2038.09.19)

4. Lin CJ, Wang TW. METHODS OF PREPARING STIMULI-RESPONSIVE MULTIFUNCTIONAL NANOPARTICLES. US Patent US 10,117,837 (2018.11.06~2037.03.01)

5. Wang LW, Wang TW. 循序崩解之帶殼多胜肽奈米載體及其製備方法Taiwan Patent 601526 (2017.10.11~2036.09.21)

6. Lu HY, Wang TW, Lin FH. Immuno-PCR Method for Detecting Nasopharyngeal Carcinoma Markers and Kit.  USA Pat. 7807347 - Issued October 5, 2010

7. Lu HY, Wang TW, Lin FH. 用於檢測鼻咽癌之免疫聚合酶連鎖反應方法及其套組Taiwan Patent 399437 (2013.06.21~2028.01.20)

8. Wang TW, Lin FH. Cell Culture Device. Taiwan Patent 393775 (2013.04.21~2028.07.29)

9. Wu HC, Lin FH, Wang TW. Magnetic ceramic nanocrystallite as non-viral gene vector and preparation for gene therapy in biomedical applications. Taiwan Patent 379689 (2012.12.21~2029.05.26)

10. Wu HC, Lin FH, Wang TW.. Magnetic Hydroxyapatite Nanoparticles and Preparation Method. Taiwan Patent 375567 (2012.11.01~2027.09.18)

11. Wang TW, Huang YC, Lin FH. Biocompatible Bilayer Porous Matrix and Preparation. Taiwan Patent 368653 (2012.07.21~2027.07.19)

12. Lin CH, Wang TW. Protein For Improving Cell-Attachment Efficiency and Use Thereof. US Patent US 11552507 - Filed Oct 24, 2006