In these pages, we intend to give an overview on the research activity about the Superconducting QUantum Interference Devices (SQUIDs) held at the institute of Applied Sciences and Intelligent Systems (ex institute of cybernetics) "E. Caianiello" of National Research Council (Italy). The group is involved in this field since the middle 90s, developing SQUID based devices for many applications such as the biomagnetism, the magnetic microscopy, the nanomagnetism, the macroscopic quantum effects, the current sensing and others. The performance of these devices are at the top of the international level as demonstrated by numerous publications in prestigious scientific international journals. Furthermore, we can design and realize SQUID device on the basis of the specific requirement and we have ongoing various partnership with other research group and industries worldwide.