A. Profile

* Detailed CV is attached as a pdf file at the end of this page

Educational Background

• Ph.D Dept. of Chemical and Biomolecular Engineering,
  College of Engineering, Yonsei University, Seoul, Korea

• • • Graduate research with Prof. Jae-Hyung Jang

    • Thesis: "The strategies for fabrication of three-dimensional electrospun scaffolds delivering stem cells and gene vectors"
      
      

• B.S. Dept. of Chemical and Biomolecular Engineering

Yonsei University, Seoul, Korea  

• Gyeonggi Science High School for the Gifted (Science Academy), Korea

Work Experiences

• 2023 ~            : Manager,  Research  Strategy Team
    Inventage Lab Inc, Seongnam-si, Korea

• 2021 ~  2023 : Research Professor, Nano Science Technology Institute
    Yonsei University, Seoul, Korea

• 2019 ~ 2021 : Technology Analyst, Manager, New Business Development
    SK Bioscience, Korea

• 2017 ~ 2019 : Post-doctoral Fellow, Simpson Querrey Institute
      Northwestern University, Chicago, IL (Advisor: Prof. Samuel I. Stupp)

• 2016 ~ 2017 : Post-doctoral researcher, Engineering Research Institute
    Yonsei University, Seoul, Korea (Advisor: Prof. Jae-Hyung Jang)

• 2016    : Visiting Researcher, Department of Chemical Engineering
    University of California, Berkeley, CA, United States (Prof. David V. Schaffer)

Involved Research Projects

• Center for Bio-inspired Energy Science (CBES), Northwestern University

• Center for Regenerative Nanomedicine (CRN), Northwestern University

• Funds from National Research Foundation (NRF) of Korea

  1. Development of adeno-associated virus-based gene delivery systems for specifically targeting human immune cells

  2. Development of 3D complex patterns from conducting polymer nanofibers 

  3. Development of elastic, injectable and self-assembling multi-layered smart nanofibrous scaffolds for spinal cord regeneration 

  4. Development of spatiotemporal tissue control system by spatial and temporal delivery of sticky gene vectors

• Funds from Ministry of Health and Welfare of Korea

  1. Protocol development of human neural stem cell specific adeno-associated virus based cell-gene therapy for spinal cord injury treatment

  2. Establishment of clinical trial protocol for gene-cell therapies using a human neural stem cell specific “brand-new” adeno-associated viral vector (AAV r3.45) 

Research Skills

• Intensive experience in polymeric engineering to produce nanofibrous matrices with a variety of micro- and macroscopic properties

• Extensive research experience for developing cell and gene delivery systems:

• material science, genomic cloning, in vitro experiments and animal studies

• Material Science / Polymer Engineering

  1. Electrospinning / post-electrospinning modification

  2. Hydrogel fabrication

  3. Polymer composites

  4. Polymer modification / synthesis / purification

  5. Peptide amphiphile (PA) synthesis / purification (HPLC, MassSpec) / engineering

  6. Characterization of mechanical (tensile, compressive and adhesive strength), rheological and chemical (NMR, IR) properties of polymeric structures

  7. Imaging including SEM, fluorescent microscopy, confocal laser scanning microscopy, etc.

• Cloning, In Vitro and In Vivo Studies

  1. AAV production / purification / transduction

  2. Cloning, transformation, and plasmid prep

  3. Cell line, and human neural stem cell culture

  4. Characterization of in vitro cell viability, and transduction efficiency (FACS analysis)

  5. Implantation surgery and characterization (immunostaining and IVIS analysis)

Awards and Honors

• National Science & Technology Scholarship awards

• Undergraduate Research Project (URP) from Korea Foundation

for the Advancement of Science and Creativity (KOFAC)

• Global Ph.D Fellowship, National Research Foundation (NRF) of Korea

• The article published in ACS Appl. Mater. Interfaces was highlighted

at Global Medical Discovery, Key Nanotechnology Article

• Selected as People who has brought great honor to Korea

(한국을 빛내는 사람들), Biological Research Information Center (BRIC) (2016.02.)

• Selected as People who has brought great honor to Korea 

(한국을 빛내는 사람들), Biological Research Information Center (BRIC) (2017.08.)