Publications
• SCI journal papers published
[2023]
Tsaokoic Acid: A New Bicyclic Nonene from the Fruits of Amomum tsao-ko with Acetylcholinesterase Inhibitory Activity. Hyunyoung Kim, Hwaryeong Lee, Hee jin Jung, Sang Gyun Noh, Isoo Youn, Hyunkyung Kwak, Yeju Lee, Sang-Jip Nam, Soosung Kang, Hae Young Chung, Eun Kyoung Seo* Molecules. 2023, 28(6), 2602. doi: 10.3390/molecules28062602.
Cornus officinalis Seed Extract Inhibits AIM2-Inflammasome Activation and Attenuates Imiquimod-Induced Psoriasis-like Skin Inflammation. Se-Bin Lee, Ju-Hui Kang, Eun-Jung Sim, ye-Rin Jung, Jeong-Hyeon Kim, Prima F Hillman, Sang-Jip Nam, Tae-Bong Kang* Int. J. Mol. Sci. 2023, 24(6), 5653. doi: 10.3390/ijms24065653.
Marinobazzanan, a Bazzanane-Type Sesquiterpenoid, Suppresses the Cell Motility and Tumorigenesis in Cancer Cells. Sultan Pulat, Prima F Hillman, Sojeong Kim, Ratnakar N Asolkar, Haerin Kim, Rui Zhou, İsa Taş, Chathurika D B Gamage, Mücahit Varlı, So-Yeon Park, Sung Chul Park, Inho Yang, Jongheon Shin, Dong-Chan Oh, Hangun Kim*, Sang-Jip Nam*, William Fenical* Mar. Drugs. 2023, 21(3), 153. doi: 10.3390/md21030153.
Sadopeptins A and B, Sulfoxide- and Piperidone-Containing Cyclic Heptapeptides with Proteasome Inhibitory Activity from a Streptomyces sp. Jiyoon Park, Jiseong Kim, Sunghoon Hwang 1 Daehyun Oh, Young Eun Du, Sang-Jip Nam, Hyeung-Geun Par, Min Jae Lee*, Dong-Chan Oh* J. Nat. Prod. 2023, 86, 3, 612-620. doi: 10.1021/acs.jnatprod.2c00978.
Glycosylated and Succinylated Macrocyclic Lactones with Amyloid-β-Aggregation-Regulating Activity from a Marine Bacillus sp. Jinsheng Cui, Suhyun Ye, Daniel Shin, Illhwan Cho, Hye Yun Kim, Yun Kwon, Keunwan Park, Sang-Jip Nam, YoungSoo Kim*, Dong-Chan Oh* Mar. Drugs 2023, 21(2), 67. Doi: 10.3390/md21020067.
1'-O-methyl-averantin isolated from the endolichenic fungus Jackrogersella sp. EL001672 suppresses colorectal cancer stemness via sonic Hedgehog and Notch signaling. Mücahit Varlı, Eun-Young Lee, Yi Yang, Rui Zhou, İsa Taş, Sultan Pulat, Chathurika D B Gamage, So-Yeon Park, Jae-Seoun Hur, Sang-Jip Nam*, Hangun Kim* Sci Rep. doi: 10.1038/s41598-023-28773-z.
Lodopyridones D - G from a marine-derived bacterium Saccharomonospora sp. Prima F Hillman, Ji Young Lee, Juri Lee, Jihye Lee, Dong-Chan Oh*, William Fenical, Sang-Jip Nam* Nat. Prod. Res. 2023, Jan 30;1-6. doi: 10.1080/14786419.2023.2173192.
Libertellenone T, a Novel Compound Isolated from Endolichenic Fungus, Induces G2/M Phase Arrest, Apoptosis, and Autophagy by Activating the ROS/JNK Pathway in Colorectal Cancer Cells. Chathurika D B Gamage, Jeong-Hyeon Kim, Yi Yang, İsa Taş, So-Yeon Park, Rui Zhou, Sultan Pulat, Mücahit Varlı, Jae-Seoun Hur, Sang-Jip Nam*, Hangun Kim* Cancers 2023, 15(2), 489. doi: 10.3390/cancers15020489.
Genomic and Spectroscopic Signature-Based Discovery of Natural Macrolactams. Yern-Hyerk Shin, Ji Hyeon Im, Ilnam Kang, Eunji Kim, Sung Chul Jang, Eunji Cho, Daniel Shin, Sunghoon Hwang, Young Eun Du, Thanh-Hau Huynh, Keebeom Ko, Yoon-Joo Ko, Sang-Jip Nam, Takayoshi Awakawa, Jeeyeon Lee, Suckchang Hong, Ikuro Abe, Bradley S Moore, William Fenical, Yeo Joon Yoon, Jang-Cheon Cho, Sang Kook Lee, Ki-Bong Oh, Dong-Chan Oh* J. Am. Chem. Soc. 2023, 145, 3, 1886-1896. doi: 10.1021/jacs.2c11527.
[2022]
SNA077, an Extract of Marine Streptomyces sp., Inhibits Melanogenesis by Downregulating Melanogenic Proteins via Inactivation of cAMP/PKA/CREB Signaling. Su-Jin Lim, Da-Won Jung, Prima F Hillman, Sang-Jip Nam*, Chang-Seok Lee* Int. J. Mol. Sci. 2022, 23(23), 14922. doi: 10.3390/ijms232314922.
Targeted Discovery of an Enediyne-Derived Cycloaromatized Compound, Jejucarboside A, from a Marine Actinomycete. Ji Hyeon Im, Daniel Shin, Yeon Hee Ban, Woong Sub Byun, Eun Seo Bae, Donghoon Lee, Young Eun Du, Jinsheng Cui, Yun Kwon, Sang-Jip Nam, Sangwon Cha, Sang Kook Lee, Yeo Joon Yoon, Dong-Chan Oh* ORG. Lett. 2022. 24. 39. 7188-7193. doi: 10.1021/acs.orglett.2c02934.
Actinopolymorphols E and F, pyrazine alkaloids from a marine sediment-derived bacterium Streptomyces sp. Sohee Kim, Prima F Hillman, Ji Young Lee, Juri Lee, Jihye Lee, Sun-Shin Cha, Dong-Chan Oh, Sang-Jip Nam*, William Fenical* J. Antibiot. 2022 Nov;75(11);619-625. doi: 10.1038/s41429-022-00562-2.
Epoxinnamide: An Epoxy Cinnamoyl-Containing Nonribosomal Peptide from an Intertidal Mudflat-Derived Streptomyces sp. Sangwook Kang, Jaeho Han, Sung Chul Jang, Joon Soo An, Ilnam Kang, Yun Kwon, Sang-Jip Nam, Sang Hee Shim, Jang-Cheon Cho, Sang Kook Lee, and Dong-Chan Oh* Mar Drugs.2022 Jul 12;20(7):455. doi: 10.3390/md20070455.
Discovery and Photoisomerization of New Pyrrolosesquiterpenoids Glaciapyrroles D and E, from Deep-Sea Sediment Streptomyces sp. Keebeom Ko, Seong-Hwan Kim, Subin Park, Hwa Seung Han, Jae Kyun Lee, Jin Wook Cha, Sunghoon Hwang, Ki Young Choi, Yoon-Jae Song, Sang-Jip Nam, Jongheon Shin, Seung-Il Nam, Hak Cheol Kwon, Jin-Soo Park*, and Dong-Chan Oh Mar Drugs. 2022, 20, 281. doi: 10.3390/md20050281.
Hamuramicin C, a Cytotoxic Bicyclic Macrolide Isolated from a Wasp Gut Bacterium. Joon Soo An, Hyun-Ju Lim, Ji Yun Lee, Yong-Joon Jang, Sang-Jip Nam, Sang Kook Lee, and Dong-Chan Oh* J. Nat. Prod, 2022, 85, 936-942. doi: 10.1021/acs.jnatprod.1c01075
Nyuzenamide C, an Antiangiogenic Epoxy Cinnamic Acid-Containing Bicyclic Peptide from a Riverine Streptomyces sp. Joon Soo An, Myoun-Su Kim, Jaeho Han, Sung Chul Jang, Ji Hyeon Im, Jinsheng Chui, Sang-Jip Nam, Jeongheon Shin, Sang Kook Lee, Yeo Joon Yeon, and Dong-Chan Oh* J. Nat. Prod, 2022, 85, 804-814. doi: 10.1021/acs.jnatprod.1c00837.
A coumarin-based reversible two-photon fluorescence probe for imaging glutathione near N-methyl-D-aspartate (NMDA) receptors. Nahyun Kwon, Chang Su Lim, Dayoung Lee, Gyeongju Ko, Jeongsun Ha, Moonyeon Cho, K. M. K. Swamy, Eun-Young Lee, Dong Joon Lee, Sang-Jip Nam, Xin Zhou*, Hwan Myung Kim*, and Juyoung Yoon* Chem Commun (Camb), 2022, 58, 3633-3636. doi: 10.1039/d1cc05512g.
Deoxyvasicinone with Anti-Melanogenic Activity from Marine-Derived Streptomyces sp. CNQ-617. Se-Eun Lee, Min-ju Kim, Prima F. Hillman, Dong-Chan Oh, William Fenical, Sang-Jip Nam*, and Kyung-Min Lim* Mar Drugs, 2022, 20, 155. doi: 10.3390/md20020155.
Ligiamycin A and B, Decalin-Amino-Maleimides from the Co-Culture of Streptomyces sp. and Achromobacter sp. Isolated from the Marine Wharf Roach, Ligia exotica. Hyung-Ju Lim, Joon Soo An, Eun Seo Bae, Eunji Cho, Sunghoon Hwang, Sang-Jip Nam, Ki-Bong Oh, Sang Kook Lee, and Dong-Chan Oh* Mar Drugs, 2022, 20(2), 83. doi: 10.3390/md20020083.
Marine Depsipeptide Nobilamide I Inhibits Cancer Cell Motility and Tumorigenicity via Suppressing Epithelial-Mesenchymal Transition and MMP2/9 Expression. Tu Cam Le, Sultan Pulat, Jihye Lee, Geum Jin Kim, Haerin Kim, Eun-Young Lee, Prima F. Hillman, Hyukjae Choi, Inho Yang, Dong-Chan Oh, Hangun Kim*, Sang-Jip Nam*, and William Fenical* ACS Omega, 2022, 7, 1722-1732. doi: 10.1021/acsomega.1c04520.
Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp. Sohee Kim, Tu Cam Le, Sang-Ah Han, Prima F. Hillman, Ahreum Hong, Sunghoon Hwang, Young Eun Du, Hiyoung Kim, Dong-Chan Oh, Sun-Shin Cha, Jihye Lee*, Sang-Jip Nam*, and William Fenical* Mar Drugs, 2022, 20, 35. doi: 10.3390/md20010035.
Erythrobacter rubeus sp. nov., a carotenoid-producing alphaproteobacterium isolated from coastal seawater. Jaewoo Yoon*, Eun-Young Lee, and Sang-Jip Nam* Arch Microbiol, 2022, 204, 125. doi: 10.1007/s00203-021-02736-2.
Gwanakosides A and B, 6-Deoxy-α-L-talopyranose-Bearing Aromatic Metabolites from a Streptomyces sp. and Coculture with Pandoraea sp. Thanh-Hau Huynh, Jayho Lee, Dong Hyun Moon, Thanh Quang Nguyen, Sangkeun Son, Sunghoon Hwang, Young Eun Du, Jinsheng Cui, Jae-Hyuk Jang, Sang-Jip Nam, Jongheon Shin, Jichan Jang, Sang Kook Lee, Ki-Bong Oh, and Dong-Chan Oh* J. Nat. Prod, 2022, 85, 83-90. doi: 10.1021/acs.jnatprod.1c00703.
[2021]
Antibacterial Meroterpenoids, Merochlorins G-J from the Marine Bacterium Streptomyces sp. Min-Ji Ryu, Prima F Hillman, Jihye Lee, Sunghoon Hwang, Eun-Young Lee, Sun-Shin Cha, Inho Yang, Dong-Chan Oh, Sang-Jip Nam*, and William Fenical* Mar Drugs, 2021, 19, 618. doi: 10.3390/md19110618.
Pseudoalteromone A, a Ubiquinone Derivative from Marine Pseudoalteromonas spp., Suppresses Melanogenesis. Su-Jin Lim, Dae-Jin Min, Sohee Kim, Jihye Lee, Eun-Soo Lee, Hyuk Kim, Sung-Yoen Cho, Heung-Soo Beak, Chang-Seok Lee*, Sang-Jip Nam*, and Jaeyoung Ko* Mar Drugs, 2021, 19, 612. doi: 10.3390/md19110612.
Potent and Selective Inhibitors of Human Monoamine Oxidase A from an Endogenous Lichen Fungus Diaporthe mahothocarpus. Geum Seok Jeong, Prima F Hillman, Myung-Gyun Kang, Sungbo Hwang, Jong-Eun Park, Sang-Jip Nam, Daeui Park, and Hoon Kim* J Fungi (Basel), 2021, 7, 876. doi: 10.3390/jof7100876.
Antibacterial Bicyclic Fatty Acids from a Korean Colonial Tunicate Didemnum sp. Hiyoung Kim, Tae Gu Lee, Inho Yang, Weihong Wang, Jungwook Chin, Jusung Lee, Boon Jo Rho, Hyukjae Choi, Sang-Jip Nam, Dongyup Hahn*, and Heonjoong Kang* Mar Drugs, 2021, 19, 521. doi: 10.3390/md19090521
Acremonamide, a Cyclic Pentadepsipeptide with Wound-Healing Properties Isolated from a Marine-Derived Fungus of the Genus Acremonium. Sojeong Kim, Chang Wook Lee, So-Yeon Park, Ratnakar N Asolkar, Haerin Kim, Geum Jin Kim, Song Jin Oh, Youngbae Kim, Eun-Young Lee, Dong-Chan Oh, Inho Yang, Man Jeong Paik, Hyukjae Choi, Hangun Kim*, Sang-Jip Nam*, and William Fenical* J. Nat. Prod, 2021, 84, 2249-2255. doi: 10.1021/acs.jnatprod.1c00305.
Chromenone Derivatives as Monoamine Oxidase Inhibitors from Marine-Derived MAR4 Clade Streptomyces sp. CNQ-031. Jong Min Oh, Chaeyoung Lee, Sang-Jip Nam, and Hoon Kim* J Microbiol Biotechnol, 2021, 31, 1022-1027. doi: 10.4014/jmb.2105.05003.
Antioxidative and anti-inflammatory activity of psiguadial B and its halogenated analogues as potential neuroprotective agents. Tara Man Kadayat, Dong Eun Kim, Sang Bong Lee, Kyungjin Jung, Sang Eun Park, Ji-Ye Hong, Jina Kim, Aarajana Shrestha, Dong-Su Kim, Hongchan An, Nayeon Kim, Su-Jeong Lee, Sugyeong Kwon, Suhui Kim, Jun Yeon Hwang, Shinae Kim, Dongyup Hahn, Hyukjae Choi, Sang-Jip Nam, Yong Hyun Jeon, Jung Jin Hwang, Sung Jin Cho, and Jungwook Chin* Bioorg Chem, 2021, 113, 105027. doi: 10.1016/j.bioorg.2021.105027.
Azetidine-Bearing Non-Ribosomal Peptides, Bonnevillamides D and E, Isolated from a Carrion Beetle-Associated Actinomycete. Yern-Hyerk Shin, Yeon Hee Ban, Jisu Shin, In Wook Park, Soljee Yoon, Keebeom Ko, Jongheon Shin, Sang-Jip Nam, Jaclyn M Winter, YoungSoo Kim, Yeo Joon Yoon, and Dong-Chan Oh* J. Org. Chem, 2021, 86, 11149-11159. doi: 10.1021/acs.joc.1c00360.
Chemical Structure and Biological Activities of Secondary Metabolites from Salicornia europaea L. Sojeong Kim, Eun-Young Lee, Prima F Hillman, Jaeyoung Ko, Inho Yang*, and Sang-Jip Nam* Molecules, 2021, 13, 2252. doi: 10.3390/molecules26082252.
Svalbamides A and B, Pyrrolidinone-Bearing Lipodipeptides from Arctic Paenibacillus sp. Young Eun Du, Eun Seo Bae, Yeonjung Lim, Jang-Cheon Cho, Sang-Jip Nam, Jongheon Shin, Sang Kook Lee, Seung-Il Nam, and Dong-Chan Oh* Mar Drugs, 2021, 17, 229. doi: 10.3390/md19040229.
Dumulmycin, an Antitubercular Bicyclic Macrolide from a Riverine Sediment-Derived Streptomyces sp. Joon Soo An, Bora Shin, Tae Ho Kim, Sunghoon Hwang, Yern-Hyerk Shin, Jinsheng Cui, Young Eun Du, Jungwoo Yi, Sang-Jip Nam, Suckchang Hong, Jongheon Shin, Jichan Jang, Yeo Joon Yoon, and Dong-Chan Oh* Org Lett, 2021, 23, 3359-3363. doi: 10.1021/acs.orglett.1c00847.
Selective Inhibition of Human Monoamine Oxidase B by 5-hydroxy-2-methyl-chroman-4-one Isolated from an Endogenous Lichen Fungus Daldinia fissa. Geum-Seok Jeong, Myung-Gyun Kang, Sang-Ah Han, Ji-In Noh, Jong-Eun Park, Sang-Jip Nam, Daeui Park, Sung-Tae Yee, and Hoon Kim* J Fungi (Basel), 2021, 7, 84. doi: 10.3390/jof7020084.
Acremonidin E produced by Penicillium sp. SNF123, a fungal endophyte of Panax ginseng, has antimelanogenic activities. Kyuri Kim, Hae-In Jeong, Inho Yang, Sang-Jip Nam*, and Kyung-Min Lim* J Ginseng Res, 2021, 45, 98-107. doi: 10.1016/j.jgr.2019.11.007.
[2020]
Discrimination of Lycium chinense and L. barbarum Based on Metabolite Analysis and Hepatoprotective Activity. Min-Ji Ryu, Minjeong Kim, Moongi Ji, Chaeyoung Lee, Inho Yang, Seong-Bin Hong, Jungwook Chin, Eun Kyoung Seo, Man-Jeong Paik*, Kyung-Min Lim*, and Sang-Jip Nam* Molecules, 2020, 25, 5835. doi: 10.3390/molecules25245835.
Bioactive natural products from the genus Salinospora: a review. Haerin Kim, Sohee Kim, Minju Kim, Chaeyoung Lee, Inho Yang*, and Sang-Jip Nam* Arch Pharm Res, 2020, 43, 1230-1258. doi: 10.1007/s12272-020-01288-1.
Colletotrichalactones A-Ca, unusual 5/6/10-fused tricyclic polyketides produced by an endophytic fungus, Colletotrichum sp. JS-0361. Sunghee Bang, Ha Eun Kwon, Ji Yun Baek, Dae Sik Jang, Soonok Kim, Sang-Jip Nam, Dongho Lee, Ki Sung Kang, and Sang Hee Shim* Bioorg Chem, 2020, 105, 104449. doi: 10.1016/j.bioorg.2020.104449.
Antaroide, a Novel Natural Nine-Membered Macrolide, Inhibits Melanin Biosynthesis in B16F10 Murine Melanoma Cells. Min-Ji Ryu, Eun-Ki Baek, Soyeon Kim, Chi Nam Seong, Inho Yang, Kyung-Min Lim, and Sang-Jip Nam* Biomol. Ther, 2021, 29, 98. doi: 10.4062/biomolther.2020.064.
Androsamide, a Cyclic Tetrapeptide from a Marine Nocardiopsis sp., Suppresses Motility of Colorectal Cancer Cells. Jihye Lee, Chathurika D B Gamage, Geum Jin Kim, Prima F Hillman, Chaeyoung Lee, Eun Young Lee, Hyukjae Choi, Hangun Kim, Sang-Jip Nam*, and William Fenical* J. Nat. Prod, 2020, 83, 3166. doi: 10.1021/acs.jnatprod.0c00815.
Sarmentosamide, an Anti-Aging Compound from a Marine-Derived Streptomyces sp. APmarine042. Eun-Soo Lee, Eun-Young Lee, Jisoo Yoon, Ahreum Hong, Sang-Jip Nam*, and Jaeyoung Ko* Mar Drugs, 2020, 18, 463. doi: 10.3390/md18090463.
Marine natural products with monoamine oxidase (MAO) inhibitory activity. Ahreum Hong, Le Cam Tu, Inho Yang, Kyung-Min Lim, and Sang-Jip Nam Pharm Biol, 2020, 58, 716-720. doi: 10.1080/13880209.2020.1790618.
Two new secondary metabolites, saccharochlorines A and B, from a marine bacterium Saccharomonospora sp. KCTC-19160. Tu Cam Le, Nikita Katila, Songhee Park, Jihye Lee, Inho Yang, Hyukjae Choi*, Dong-Young Choi*, and Sang-Jip Nam* Bioorg Med Chem Lett, 2020, 30, 127145. doi: 10.1016/j.bmcl.2020.127145.
An Activatable AIEgen Probe for High-Fidelity Monitoring of Overexpressed Tumor Enzyme Activity and Its Application to Surgical Tumor Excision. Haidong Li, Qichao Yao, Feng Xu, Yueqing Li, Dayeh Kim, Jeewon Chung, Gain Baek, Xiaofeng Wu, Prima Fitria Hillman, Eun Young Lee, Haoying Ge, Jiangli Fan, Jingyun Wang, Sang-Jip Nam, Xiaojun Peng*, and Juyoung Yoon* Angew Chem Int Ed Engl, 2020, 59, 10186-10195. doi: 10.1002/anie.202001675.
Salvianolic Acid B Inhibits Hand-Foot-Mouth Disease Enterovirus 71 Replication through Enhancement of AKT Signaling Pathway. So-Hee Kim, Jihye Lee, Ye Lin Jung, Aerum Hong, Sang-Jip Nam*, and Byung-Kwan Lim* J Microbiol Biotechnol, 2020, 30, 38-43. doi: 10.4014/jmb.1907.07079.
[2019]
Neuroprotective Glycosylated Cyclic Lipodepsipeptides, Colletotrichamides A–E, from a Halophyte-Associated Fungus, Colletotrichum gloeosporioides JS419. Sunghee Bang, Changyeol Lee, Soonok Kim, Ji Hoon Song, Ki Sung Kang, Stephen T Deyrup, Sang-Jip Nam*, Xuekui Xia*, and Sang Hee Shim* J. Org. Chem, 2019, 84, 10999-11006. doi: 10.1021/acs.joc.9b01511.
Mycousfurans A and B, Antibacterial Usnic Acid Congeners from the Fungus Mycosphaerella sp., Isolated from a Marine Sediment. Jihye Lee, Jusung Lee, Geum Jin Kim, Inho Yang, Weihong Wang, Joo-Won Nam, Hyukjae Choi, Sang-Jip Nam*, and Heonjoong Kang* Mar. Drugs, 2019, 17, 22. doi: 10.3390/md17070422.
Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity. Ji Yoon Beom, Jin A Jung, Kyung-Tae Lee, Areum Hwangbo, Myoung Chong Song, Yeonseon Lee, Soo Jung Lee, Ji Hoon Oh, Sang-Jun Ha, Sang-Jip Nam, Eunji Cheong,* Yong-Sun Bahn,* and Yeo Joon Yoon* J. Nat. Prod, 2019, 82, 2078. doi: 10.1021/acs.jnatprod.9b00144.
Meroindenon and Merochlorins E and F, Antibacterial Meroterpenoids from a Marine-Derived Sediment Bacterium of the Genus Streptomyces. Min-Ji Ryu, Sunghoon Hwang, Sojeong Kim, Inho Yang, Dong-Chan Oh, Sang-Jip Nam* and William Fenical* Org. Lett., 2019, 21, 5779-5783. doi: 10.1021/acs.orglett.9b01440.
Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivatives. Jong Min Oh, Myung-Gyun Kang, Ahreum Hong, Ji-Eun Park, Soo Hyun Kim, Jae Pil Lee, Seung Cheol Baek, Daeui Park, Sang-Jip Nam, Myoung-Lae Cho, and Hoon Kim* Int. J. Biol. Macromol., 2019, 137, 426-432. doi: 10.1016/j.ijbiomac.2019.06.167.
Gentiopicroside isolated from Gentiana scabra Bge. inhibits adipogenesis in 3T3-L1 cells and reduces body weight in diet-induced obese mice. Ra-Yeong Choi, Sang-Jip Nam, Hae-In Lee, Jihye Lee, Alain S. Leutou, Ju Ri Ham, and Mi-KyungLee* Bioorg. Med. Chem. Lett., 2019, 29, 1699-1704. doi: 10.1016/j.bmcl.2019.05.038.
Saccharoquinoline, a Cytotoxic Alkaloidal Meroterpenoid from Marine-Derived Bacterium Saccharomonospora sp. Tu Cam Le, Eun Ju Lee, Jihye Lee, Ahreum Hong, Chae-Yoon Yim, Inho Yang, Hyukjae Choi, Jungwook Chin, Sung Jin Cho, Jaeyoung Ko, Hayoung Hwang,* Sang-Jip Nam* and William Fenical* Mar. Drugs, 2019, 17, 98. doi: 10.3390/md17020098.
[2018]
Scalalactams A–D, Scalarane Sesterterpenes with a γ-Lactam Moiety from a Korean Spongia Sp. Marine Sponge. Inho Yang , Jusung Lee, Jihye Lee, Dongyup Hahn, Jungwook Chin, Dong Hwan Won, Jaeyoung Ko, Hyukjae Choi, Ahreum Hong, Sang-Jip Nam* and Heonjoong Kang* Molecules, 2018, 23, 3187. doi: 10.3390/molecules23123187.
Seongsanamides A–D: Antiallergic Bicyclic Peptides from Bacillus safensis KCTC 12796BP. Geum Jin Kim, Xian Li, Seong-Hwan Kim, Inho Yang, Dongyup Hahn, Jungwook Chin, Sang-Jip Nam, Joo-Won Nam, Doo Hyun Nam, Dong-Chan Oh, Hyeun Wook Chang,* and Hyukjae Choi* Org. Lett., 2018, 20, 7539-7543. doi: 10.1021/acs.orglett.8b03293.
Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificus. Soo-Bong Park, Da-Woon Bae, Nina Abigail B. Clavio, Lei Zhao, Chang-Sook Jeong, Bo Mee Choi, Stephani Joy Y. Macalino, Hee-Jeong Cha, Jin-Byung Park, Jun Hyuck Lee, Sang-Jip Nam, Sun Choi,* Min-Kyu Kim,* and Sun-Shin Cha* J. Agric. Food Chem., 2018, 66, 10608-10616. doi: 10.1021/acs.jafc.8b03647.
Enantioselective Synthesis of a Novel Thiazoline Core as a Potent Peroxisome Proliferator-Activated Receptor δ Agonist. Su-Jeong Lee, Mallesham Samala, Seo Yeon Woo, Dongyup Hahn, Dayoung Kim, Tara Man Kadayat, Kyungjin Jung, Jina Kim, Dong-Su Kim, Sugyeong Kwon, Shinae Kim, Kyung-Hee Kim, Sang-Jip Nam, Sung Jin Cho,* and Jungwook Chin* ACS Omega. 2018, 3, 1970-1976. doi: 10.1021/acsomega.7b01689.
Decursin and Z-Ligustilide in Angelica tenuissima Root Extract Fermented by Aspergillus oryzae Display Anti-Pigment Activity in Melanoma Cells. Yuna Park, Dayoung Kim, Inho Yang, Bomee Choi, Jin Woo Lee, Seung Namkoong, Hyun Jung Koo, Sung Ryul Lee, Myung Rye Park, Hyosun Lim, Youn Kyu Kim,* Sang Jip Nam,* Eun-Hwa Sohn* J. Microbiol. Biotechnol., 2018, 28, 1061-1067. doi: 10.4014/jmb.1812.02044.
Antartin, a Cytotoxic Zizaane-Type Sesquiterpenoid from a Streptomyces sp. Isolated from an Antarctic Marine Sediment. Dayoung Kim, Eun Ju Lee, Jihye Lee, Alain S. Leutou, Yern-Hyerk Shin, Bomi Choi, Ji Sun Hwang, Dongyup Hahn, Hyukjae Choi, Jungwook Chin, Sung Jin Cho, Yong Deog Hong, Jaeyoung Ko, Chi Nam Seong, Katherine N. Maloney, Dong-Chan Oh, Inho Yang,* Hayoung Hwang,* and Sang-Jip Nam* Mar. Drugs, 2018, 16, 130. doi: 10.3390/md16040130.
A commensal strain of Staphylococcus epidermidis protects against skin neoplasia. Jae-young Han, Tiffany H. Chen, Anna M. Butcher, Lynnie L. Trzoss, Sang-Jip Nam, Karina T. Shirakawa, Wei Zhou, Julia Oh, Michael Otto, William Fenical, and Richard L. Gallo* Sci Adv., 2018, 4, eaao4502. doi: 10.1126/sciadv.aao4502.
Cholic Acid Attenuates ER Stress-Induced Cell Death in Coxsackievirus-B3 Infection. Teruaki Nakatsuji, TiffanyJae-young Han, Hae In Jeong, Cheol-woo Park, Jisoo Yoon, Jaeyoung Ko, Sang-Jip Nam*, Byung-Kwan Lim* J Microbiol Biotechnol., 2018, 28, 109-114. doi: 10.4014/jmb.1708.08009.
Citreibacter salsisoli gen. nov., sp. nov., a bacterium isolated from marine soil. Jaewoo Yoon, Min Kyoung Choi, Sang-Jip Nam* Arch Microbiol., 2018, 200, 445-451. doi: 10.1007/s00203-017-1451-5.
Colorimetric and Fluorescent Detecting Phosgene by a Second-Generation Chemosensor. Ying Hu, Xin Zhou, Hyeseung Jung, Sang-Jip Nam, Myung Hwa Kim*, and Juyoung Yoon* Anal Chem., 2018, 90, 3382-3386. doi: 10.1021/acs.analchem.7b05011.
Acetonic extracts of the endolichenic fungus EL002332 isolated from Endocarpon pusillum exhibits anticancer activity in human gastric cancer cells. Yi Yang, Woo Kyun Baec, Sang-Jip Nam, Min-Hye Jeong, Rui Zhou, So-Yeon Park, İsa Taş, Yun-Ho Hwang, Myong-Suk Park, Ik Joo Chung, Kyung Keun Kim, Jae-Seoun Hur, Han gun Kim Phytomedicine, 2018, 40, 106-115. doi: 10.1016/j.phymed.2018.01.006.
Naphthalene-based fluorescent probes for glutathione and their applications in living cells and patients with sepsis. Jun Li, Younghee Kwon, Kyung Soo Chung, Chang Su Lim, Dayoung Lee, Yongkang Yue, Jisoo Yoon, Gyoungmi Kim, Sang-Jip Nam, Youn Wook Chung, Hwan Myung Kim, Caixia Yin, Ji-Hwan Ryu, Juyoung Yoon* Theranostics., 2018, 8, 1411-1420. doi: 10.7150/thno.22252.
A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristics. Liyan Chen, Chang Su Lim, Dayoung Kim, Sang-Jip Nam, Woolin Lee, Gyungmi Kim, Hwan Myung Kim, and Juyoung Yoon* Chem. Commun., 2017, 53, 4791-4794. doi: 10.1039/c7cc01695f.
[2017]
Saccharomonopyrones A–C, New -Pyrones from a Marine Sediment-Derived Bacterium Saccharomonospora sp. CNQ-490. Chae-Yoon Yim, Tu Cam Le, Tae Gu Lee, Inho Yang, Hansol Choi, Jusung Lee, Kyung-Yun Kang, Jin Sil Lee, Kyung-Min Lim, Sung-Tae Yee, Heonjoong Kang*, Sang-Jip Nam*, and William Fenical* Mar. Drugs., 2017, 8, 239. doi: 10.3390/md15080239.
Identification of Antiangiogenic Potential and Cellular Mechanisms of Napyradiomycin A1 Isolated from the Marine-Derived Streptomyces sp. YP127. Ji Sun Hwang, Geum Jin Kim, Hyun Gyu Choi, Min Cheol Kim, Dongyup Hahn, Joo-Won Nam, Sang-Jip Nam, Hak Choel Kwon, Jungwook Chin, Sung Jin Cho, Hayoung Hwang*, and Hyukjae Choi* J. Nat. Prod., 2017, 8, 2269-2275. doi: 10.1021/acs.jnatprod.7b00211.
Lodopyridones B and C from a marine sediment-derived bacterium Saccharomonospora sp. Tu Cam Le, Chae-Yoon Yim, Songhee Park, Nikita Katila, Inho Yang, Myoung Chong Song, Yeo Joon Yoon, Dong-Young Choi, Hyukjae Choi*, Sang-Jip Nam*, and William Fenical* Bioorg. Med. Chem. Lett., 2017, 14, 3123-3126. doi: 10.1016/j.bmcl.2017.05.035.
Anti-Pigmentary Effect of (-)-4-Hydroxysattabacin from the Marine-Derived Bacterium Bacillus sp. Kyuri Kim, Alain S. Leutou, Haein Jeong, Dayoung Kim, Chi Nam Seong, Sang-Jip Nam*, and Kyung-Min Lim* Mar. Drugs., 2017, 15, 138. doi: 10.3390/md15050138.
Enabling techniques in the search for new antibiotics: Combinatorial biosynthesis of sugar-containing antibiotics. Je Won Park, Sang-Jip Nam, and Yeo Joon Yoon* Biochem. Pharmacol., 2017, 134, 56-73. Doi: 10.1016/j.bcp.2016.10.009.
Cholic acid attenuate ER stress induced cell death in coxsackievirus-1 B3 infection Jae-young Han, Hae In Jeong, Cheol-woo Park, Jisoo Yoon, Jaeyoung Ko, Sang-Jip Nam, and Byung-Kwan Lim* J. Microbiol. Biotechnol., 2017. doi: 10.4014/jmb.1708.08009.
Biosynthetic pathways of aminoglycosides and their engineering. Je Won Park, Yeon Hee Ban, Sang-Jip Nam, Sun-Shin Cha, and Yeo Joon Yoon* Curr. Opin. Biotechnol., 2017, 48, 33-41. doi: 10.1016/j.copbio.2017.03.019.
Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis. Myoun-Su Kim, Wan-Je Cho, Myoung Chong Song, Seong-Whan Park, Kaeun Kim, Eunji Kim, Naryeong Lee, Sang-Jip Nam, Ki-Hoon Oh*, and Yeo Joon Yoon* Microb. Cell. Fact., 2017, 16, 9. doi: 10.1186/s12934-017-0626-8.
Potent Inhibition of Monoamine Oxidase B by a Piloquinone from Marine-Derived Streptomyces sp. CNQ-027. Hyun Woo Lee, Hansol Choi, Sang-Jip Nam, William Fenical, and Hoon Kim* J. Microbiol. Biotechnol., 2017, 27, 785-790. doi: 10.4014/jmb.1612.12025.
Cadiolides J–M, antibacterial polyphenyl butenolides from the Korean tunicate Pseudodistoma antinboja. Weihong Wang, Hiyoung Kim, Rahul S. Patil, Awadut G. Giri, Dong Hwan Won, Dongyup Hahn, Youjung Sung, Jusung Lee, Hyukjae Choi, Sang-Jip Nam, and Heonjoong Kang* Bioorg. Med. Chem. Lett., 2017, 27, 574-577. doi: 10.1016/j.bmcl.2016.12.016.
An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells. Nahyun Kwon, Myoung Ki Cho, Sang Jun Park, Dayoung Kim, Sang-Jip Nam, Lei Cui,* Hwan Myung Kim,* and Juyoung Yoon* Chem. Commun., 2017, 53, 525-528. doi: 10.1039/c6cc08971b.
Potent Selective Inhibition of Monoamine Oxidase A by Alternariol Monomethyl Ether Isolated from Alternaria brassicae. Hyun Woo Lee, Yeon Ji Kim, Sang-Jip Nam, and Hoon Kim* J. Microbiol. Biotechnol., 2017, 27, 316-320. doi: 10.4014/jmb.1610.10053.
[2016]
A new secoiridoid glycoside from the fruits of Cornus officinalis (Cornaceae). Ji-Yeon Park, Ah-Reum Han, Yun-Seo Kil, Unwoo Kang, Se-Hee Kim, Sang-Jip Nam*, and Eun Kyoung Seo* Nat. Prod. Res., 2016, 13, 1504-1510. doi: 10.1080/14786419.2015.1115996.
Acredinone C and the Effect of Acredinones on Osteoclastogenic and Osteoblastogenic Activity. Jeong-Tae Yeon, Hiyoung Kim, Kwang-Jin Kim, Jihye Lee, Dong Hwan Won, Sang-Jip Nam, Seong Hwan Kim, Heonjoong Kang*, and Young-Jin Son* J. Nat. Prod., 2016, 7, 1730-1736. doi: 10.1021/acs.jnatprod.6b00004.
Missassigned natural products and their revised structures. Hye-Dong Yoo, Sang-Jip Nam, Young-Won Chin, and Min-Sun Kim* Arch. Pharm. Res., 2016, 39, 143-153. doi: 10.1007/s12272-015-0649-9
Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin. Eunji Kim, Myoung Chong Song, Myoun Su Kim, Ji Yoon Beom, Eun Yeol Lee, Dong-Myung Kim, Sang-Jip Nam, and Yeo Joon Yoon* J. Nat. Prod., 2016, 8, 2014-2021. doi: 10.1021/acs.jnatprod.6b00267.
A Selective Imidazoline-2-thione-Bearing Two-Photon Fluorescent Probe for Hypochlorous Acid in Mitochondria. Qingling Xu, Cheol Ho Heo, Jin A. Kim, Hye Sue Lee, Ying Hu, Dayoung Kim, Kunemadihalli Mathada Kotraiah Swamy, Gyoungmi Kim, Sang-Jip Nam, Hwan Myung Kim*, and Juyoung Yoon* Anal. Chem., 2016, 12, 6615-6620. doi: 10.1021/acs.analchem.6b01738.
Ansalactams B–D Illustrate Further Biosynthetic Plasticity within the Ansamycin Pathway. Tu Cam Le, Inho Yang, Yeo Joon Yoon, Sang-Jip Nam*, and William Fenical* Org. Lett., 2016, 9, 2256-2259. Doi: 10.1021/acs.orglett.6b00892.
The Halicylindramides, Farnesoid X Receptor Antagonizing Depsipeptides from a Petrosia sp. Marine Sponge Collected in Korea. Dongyup Hahn, Hiyoung Kim, Inho Yang, Jungwook Chin, Hoosang Hwang, Dong Hwan Won, Byoungchan Lee, Sang-Jip Nam, Merrick Ekins, Hyukjae Choi*, and Heonjoong Kang* J. Nat. Prod., 2016, 79, 499-506. doi: 10.1021/acs.jnatprod.5b00871.
The Protective Effects of Alisol A 24-Acetate from Alisma canaliculatum on Ovariectomy Induced Bone Loss in Vivo. Yun-Ho Hwang, Kyung-Yun Kang, Sung-Ju Lee, Sang-Jip Nam, Young-Jin Son, and Sung-Tae Yee 1* Molecules., 2016, 21, 74. Doi: 10.3390/molecules21010074.
[2015]
Monanchosterols A and B, Bioactive Bicyclo[4.3.1]steroids from a Korean Sponge Monanchora sp. Weihong Wang, Tae Gu Lee, Rahul S. Patil, Bora Mun, Inho Yang, Hiyoung Kim, Dongyup Hahn, Dong Hwan Won, Jihye Lee, Yehee Lee, Hyukjae Choi, Sang-Jip Nam,* and Heonjoon Kang* J. Nat. Prod., 2015, 78, 368-373. doi: 10.1021/np500760v.
Acredinones A and B, Voltage-Dependent Potassium Channel Inhibitors from the Sponge-Derived Fungus Acremonium sp. F9A015. Hiyoung Kim, Inho Yang, Shin-Young Ryu, Dong Hwan Won, Awadut G. Giri, Weihong Wang, Hyukjae Choi, Jungwook Chin, Dongyup Hahn, Eunhee Kim, Chulkyeong Han, Jihye Lee, Sang-Jip Nam, Won-Kyung Ho, and Heonjoon Kang* J. Nat. Prod., 2015, 78, 363-367. doi: 10.1021/np5007586.
Munhyung Bae, Heegyu Kim, Kyuho Moon, Sang-Jip Nam, Jongheon Shin, Ki-Bong Oh, and Dong-Chan Oh* “Mohangamides A and B, New Dilactone-Tethered Pseudo-Dimeric Peptides Inhibiting Candida albicans Isocitrate Lyase” Org. Lett., 2015, 17, 712-715.
Visualization of Endogenous and Exogenous Hydrogen Peroxide Using A Lysosome-Targetable Fluorescent Probe. Dabin Kim, Gyoungmi Kim, Sang-Jip Nam, Jun Yin, and Juyoung Yoon* Sci. Rep, 2015, 5, 8488.
Actinobenzoquinoline and Actinophenanthrolines A–C, Unprecedented Alkaloids from a Marine Actinobacterium. Sang-Jip Nam, Christopher A. Kauffman, Paul R. Jensen, Curtis E. Moore, Arnold L. Rheingold, and William Fenical* Org. Lett., 2015, 17, 3240-3243. doi: 10.1021/acs.orglett.5b01387.
Inhibition of Monoamine Oxidase by Anithiactins from Streptomyces sp. Hyun Woo Lee, Won Kyeong Jung, Hee Jung Kim, Yu Seok Jeong, Sang-Jip Nam, Heonjoon Kang, and Hoon Kim* J. Microbiol. Biotechnol., 2015, 25, 1425-1428. doi: 10.4014/jmb.1505.05020.
Previously Uncultured Marine Bacteria Linked to Novel Alkaloid Production. Eun Ju Choi, Sang-Jip Nam, Lauren Paul, Deanna Beatty, Christopher A. Kauffman, Paul R. Jensen, William Fenical* Chem. Biol., 2015, 22, 1270-1279. doi: 10.1016/j.chembiol.2015.07.014.
The Inhibitory Effect of Alisol A 24-Acetate from Alisma canaliculatum on Osteoclastogenesis. Kwang-Jin Kim, Alain Simplice Leutou, Jeong-Tae Yoen, Sik-Won Choi, Seong Hwan Kim, Sun-Tae Yee, Kyung Hee Choi, Sang-Jip Nam,* and Young-Jin Son* Int. J. Endocrinol., 2015, 132436. doi: 10.1155/2015/132436.
Simultaneous analysis of seven 2-hydroxy fatty acids as tert-butyldimethylsilyl derivatives in plasma by gas chromatography–mass spectrometry. Chan Seo, Jaehwan Yoon, Yumie Rhee, Jong-Jin Kim, Sang-Jip Nam, Wonjae Lee, Gwang Lee, Sung-Tae Yee, and Man-Jeong Paik* Biomed. Chromatogr., 2015, 29, 156-160. Doi: 10.1002/bmc.3251.
Placotylene A, an Inhibitor of the Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclast Differentiation, from a Korean Sponge Placospongia sp. Hiyoung Kim, Kwang-Jin Kim, Jeong-Tae Yoen, Seong Hwan Kim, Dong Hwan Won, Hyukjae Choi, Sang-Jip Nam, Young-Jin Son, and Heonjoon Kang* Mar. Drugs, 2014, 12, 2054-2065. doi: 10.3390/md12042054.
[2014]
Anithiactins A–C, Modified 2-Phenylthiazoles from a Mudflat-Derived Streptomyces sp. Hiyoung Kim, Inho Yang, Rahul S. Patil, Sinwoo Kang, Jihye Lee, Hyukjae Choi, Min-Sun Kim, Sang-Jip Nam,* Heonjoon Kang* J. Nat. Prod., 2014, 77, 2716-2719. doi: 10.1021/np500558b.
Phorbaketals L–N, Cytotoxic Sesterterpenoids Isolated from the Marine Sponge of the Genus Phorbas. Yehee Lee, Weihong Wang, Hiyoung Kim, Awadut G. Giri, Dong Hwan Won, Dongyup Hahn, Kyung Ryul Baek, Jihye Lee, Inho Yang, Hyukjae Choi, Sang-Jip Nam*, and Heonjoong Kang* Bioorg. Med. Chem. Lett., 2014, 24, 4095-4098. Doi: 10.1016/j.bmcl.2014.07.066.
Microbial Biosynthesis of Medicinally Important Plant Secondary Metabolites. Myoung Chong Song, Eun Ji Kim, Eunji Kim, Kris Rathwell, Sang-Jip Nam, and Yeo Joon Yoon* Nat. Prod. Rep., 2014, 31, 1497-1509. Doi: 10.1039/c4np00057a.
Cytotoxic 5α,8α-epidioxy Sterols from the Marine Sponge Monanchora sp. Bora Mun, Weihong Wang, Hiyoung Kim, Dongyup Hahn, Inho Yang, Dong Hwan Won, Eun-hee Kim, Jihye Lee, Chulkyeong Han, Hyunji Kim, Merrick Ekins, Sang-Jip Nam, Hyukjae Choi, Heonjoong Kang* Arch. Phar. Res., 2015, 38, 18-25. doi: 10.1007/s12272-014-0480-8.
Anmindenols A and B, Inducible Nitric Oxide Synthase Inhibitors from a Marine-Derived Streptomyces sp. Jihye Lee, Hiyoung Kim, Tae Gu Lee, Inho Yang, Dong Hwan Won, Hyukjae Choi, Sang-Jip Nam*, and Heonjoong Kang* J. Nat. Prod., 2014, 77, 1528-1531. doi: 10.1021/np500285a.
An Antibacterial 9,11-Secosterol from a Marine Sponge Ircinia sp. Inho Yang, Hyukjae Choi, Dong Hwan Won, Sang-Jip Nam*, and Heonjoong Kang* Bull. Korean. Chem, Soc., 2014, 35, 3360-3362. doi: 10.5012/bkcs.2014.35.11.3360.
Sesquiterpenoids with PPARd agonistic effect from a Korean marine sponge Ircinia sp. Dongyup Hahn, Jungwook Chin, Hiyoung Kim, Inho Yang, Dong Hwan Won, Merrick Ekins, Hyukjae Choi, Sang-Jip Nam*, and Heonjoong Kang* Tetrahedron Lett., 2014, 55, 4716-4719. doi: 10.1016/j.tetlet.2014.07.019.
[2013]
Actinoranone, a Cytotoxic Meroterpenoid of Unprecedented Structure from a Marine Adapted Streptomyces sp. Sang-Jip Nam, Christopher A. Kauffman, Lauren A. Paul, Paul R. Jensen, and William Fenical* Org. Lett., 2013, 15, 5400-5403. doi: 10.1021/ol402080s.
Phosphoiodyns A and B, Unique Phosphorus-Containing Iodinated Polyacetylenes from a Korean Sponge Placospongia sp. Hiyoung Kim, Jungwook Chin, Hyukjae Choi, Kyungryul Baek, Tae-Gu Lee, Seong Eon Park, Weihong Wang, Dongyup Hahn, Inho Yang, Jihye Lee, Bora Mun, Merrick Ekins, Sang-Jip Nam*, and Heongjoong Kang* Org. Lett., 2013, 15, 100-103. doi: 10.1021/ol3031318.
Bioactive Sesterterpenoids from a Korean Sponge Monanchora sp. Weihong Wang, Bora Mun, Yehee Lee, Mallepally Venkat Reddy, Youngmin Park, Jihye Lee, Hiyoung Kim, Dongyup Hahn, Jungwook Chin, Merrick Ekins, Sang-Jip Nam*, and Heonjoong Kang* J. Nat. Prod., 2013, 76, 170-177. Doi: 10.1021/np300573m.
Structures and Comparative Characterization of Biosynthetic Gene Clusters for Cyanosporasides, Enediyne-Derived Natural Products from Marine Actinomycetes. Amy L. Lane, Sang-Jip Nam, Takashi Fukuda, Kazuya Yamanaka, Christopher A. Kauffman, Paul R. Jensen, William Fenical, and Bradley S. Moore* J. Am. Chem. Soc., 2013, 135, 4171-4174. doi: 10.1021/ja311065v.
Cytotoxic scalarane sesterterpenes from a Korean marine sponge Psammocinia sp. Dongyup Hahn, Dong Hwan Won, Bora Mun, Hiyoung Kim, Chulkyeong Han, Weihong Wang, Taeho Chun, Sunhee Park, Dajeong Yoon, Hyukjae Choi, Sang-Jip Nam, Merrick Ekins, Jungwook Chin, and Heonjoong Kang* Bioorg. Med. Chem. Lett., 2013, 23, 2336-2339. doi: 10.1016/j.bmcl.2013.02.061.
Tripartin, a Histone Demethylase Inhibitor from a Bacterium Associated with a Dung Beetle Larva. Seong-Hwan Kim, So Hee Kwon, Seon-Hui Park, Jae Kyun Lee, Hea-Son Bang, Sang-Jip Nam, Hak Cheol Kwon, Jongheon Shin, and Dong-Chan Oh* Org. Lett., 2013, 15, 1834-1837. doi: 10.1021/ol4004417.
Potential Chemopreventive Activity of a New Macrolide Antibiotic from a Marine-Derived Micromonospora sp. Skylar Carlson, Laura Marler, Sang-Jip Nam, Bernard D. Santarsiero, John M. Pezzuto, and Brian T. Murphy * Mar. Drugs., 2013, 11, 1152-1161. doi: 10.3390/md11041152.
Nocardiamides A and B, Two Cyclohexapeptides from the Marine-Derived Actinomycete Nocardiopsis sp. CNX037. Zheng-Chao Wu, Sumei Li, Sang-Jip Nam, Zhong Liu, and Changsheng Zhang * J. Nat. Prod., 2013, 76, 694-701. doi: 10.1021/np400009a.
Anthracimycin, a Potent Anthrax Antibiotic from a Marine-Derived Actinomycete. Kyoung Hwa Jang, Sang-Jip Nam, Jeffrey B. Locke, Christopher A. Kauffman, Deanna S. Beatty, Lauren A. Paul, and William Fenical* Angew.Chem. Int. Ed. Engl., 2013, 52, 7822-7824. Doi: 10.1002/anie.201302749.
[2012]
Antibacterial Butenolides from the Korean Tunicate Pseudodistoma antinboja. Weihong Wang, Hiyoung Kim, Sang-Jip Nam, Boon Jo Rho, and Heonjoong Kang* J. Nat. Prod., 2012, 75, 2049-2054. doi: 10.1021/np300544a.
Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. Nina M Haste, Wdee Thienphrapa, Dan N Tran, Sandra Loesgen, Peng Sun, Sang-Jip Nam, Paul R. Jensen, William Fenical, George Sakoulas, Victor Nizet, and Mary E. Hensler* J. Antibiot., 2012, 65, 593-598. doi: 10.1038/ja.2012.77.
Structure Assignment of Lucentamycin E and Revision of the Olefin Geometries of the Marine-Derived Lucentamycins. Jin Wook Cha, Jin-Soo Park, Taebo Sim, Sang-Jip Nam, Hak Cheol Kwon*, and William Fenical* J. Nat. Prod., 2012, 75, 1648-1651. doi: 10.1021/np3003854.
Phorone A and Isophorbasone A, Sesterterpenoids Isolated from the Marine Sponge Phorbas sp. Weihong Wang, Yehee Lee, Tae Gu Lee, Bora Mun, Awadut G. Giri, Jihye Lee, Hiyoung Kim, Dongyup Hahn, Inho Yang, Jungwook Chin, Hyukjae Choi, Sang-Jip Nam*, and Heonjoong Kang* Org. Lett., 2012, 14, 4486-4489. doi: 10.1021/ol3019874.
Suppression of nitric oxide synthase by thienodolin in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells. Eun-Jung Park, John M. Pezzuto*, Kyoung Hwa Jang, Bora, Sang-Jip Nam, Sergio A. Bucarey, and William Fenical Nat. Prod. Commun, 2012, 7, 789-794. doi: 10.1177/1934578X1200700625.
Merochlorins a-d, Cyclic Meroterpenoid Antibiotics Biosynthesized in Divergent Pathways with Vanadium-dependent Chloroperoxidases. Leonard Kaysser,§ Peter Bernhardt,§ Sang-Jip Nam,§ Sandra Koesgen, J. Graham Ruby, Peter Skewes-Cox, Paul R. Jensen, William Fenical*, and Bradley S. Moore* J. Am. Chem. Soc., 2012, 134, 8625-8632. (§: These authors contributed equally to this work). doi: 10.1021/ja305665f.
Bacterial Biosynthesis and Maturation of the Didemnin Anti-cancer Agents. Ying Xu, Roland D. Kersten, Sang-Jip Nam, Liang Lu, Abdulaziz M. Al-Suwailem, Huajun Zheng, William Fenical, Pieter C. Dorrestein, Bradley S. Moore*, and Pei-Yuan Qian* J. Am. Chem. Soc., 2012, 134, 8625-8632. doi: 10.1021/ja301735a.
Discovery, design and synthesis of Y-shaped peroxisome proliferator-activated receptor δ agonists as potent anti-obesity agents in vivo. Jungyeob Ham, Hoosang Hwang, Euno Kim, Jeong-ah Kim, Sung Jin Cho, Jaeyoung Ko, Woojin Lee, Jaehwan Lee, Harish Holla, Joydeep Banerjee, Seokho Kim, Inho Yang, Hyun Joo Lee, Kyoungjin Shin, Hyukjae Choi, Sang-Jip Nam, Jungae Tak, Dongyup Hahn, Taekyun Oh, Dong Hwan Won, Tae Gu Lee, Jihye Choi, Mi Sun Park, Chaok Seok, Jungwook Chin, Heonjoong Kang Eur. J. Med. Chem., 2012, 53, 190-202. doi: 10.1016/j.ejmech.2012.03.055.
Novel Bacterial Metabolite Merochlorin A Demonstrates in vitro Activity against Multi-Drug Resistant Methicillin-Resistant Staphylococcus Aureus. George Sakoulas, Sang-Jip Nam, Sandra Loesgen, William Fenical, Paul R. Jensen, Victor Nizet, and Mary Hensler PLoS One. 2012, 7, e29439. doi: 10.1371/journal.pone.0029439.
Sterols from a soft coral, Dendronephthya gigantea as farnesoid X-activated receptor antagonists. Kyoungjin Shin, Jungwook Chin, Dongyup Hahn, Jaehwan Lee, Hoosang Hwang, Dong Hwan Won, Jungyeob Ham, Hyukjae Choi, Eunsoo Kang, Hiyoung Kim, Moon Kyeong Ju, Sang-Jip Nam,* and Heonjoong Kang* Steroids. 2012, 77, 355-359. doi: 10.1016/j.steroids.2011.12.027.
[2011]
Structure and Biosynthesis of the Marine Streptomycete Ansamycin Ansalactam A and Its Distinctive Branched Chain Polyketide Extender Unit. Micheal C. Wilson,§ Sang-Jip Nam,§ Tobias A. M. Gulder, Christopher A. Kauffman, Paul R. Jensen, William Fenical,* and Bradley S. Moore* J. Am. Chem. Soc., 2011, 133, 1971-1977. doi: 10.1021/ja109226s.
Isolation and Characterization of Actinoramides A–C, Highly Modified Peptides from a Marine Streptomyes sp. Sang-Jip Nam, Christopher A. Kauffman, Paul R. Jensen, and William Fenical* Tetrahedron, 2011, 67, 6707-6712. doi: 10.1016/j.tet.2011.04.051.
A Mass Spectrometry–guided Genome Mining Approach for Natural Product Peptidogenomics. Roland D. Kersten, Yu-Liang Yang, Yuquan Xu, Peter Cimermancic, Sang-Jip Nam, William Fenical, Michael A. Fischbach, Bradley S. Moore,* and Pieter C. Dorrestein* Nat. Chem. Biol., 2011, 7, 794-802. Doi: 10.1038/nchembio.684.
Fijimycins A–C, Three Antibacterial Etamycin-class Depsipeptides from a Marine-derived Streptomyces sp. Peng Sun, Katherine N. Maloney, Sang-Jip Nam, Nina M. Haste, Ritesh Raju, William Aalbersberg, Paul R. Jensen, Victor Nizet, Mary E. Hensler, and William Fenical* Bioorg. Med. Chem., 2011, 19, 6557-6562. Doi: 10.1016/j.bmc.2011.06.053.
Evolution of Secondary Metabolite Genes in Three Closely Related Marine Actinomycete Species. Kelle C. Freel, Sang-Jip Nam, William Fenical and Paul Jensen* Appl. Environ. Microbiol., 2011, 77, 7261-7270. doi: 10.1128/AEM.05943-11.
The Discovery of Salinosporamide K from the Marine Bacterium Salinispora pacifica by Genome Mining Gives Insight into Pathway Evolution. Alessandra S. Eustáquio, Sang-Jip Nam, Kevin Penn, Anna Lechner, Micheal C. Wilson, William Fenical, Paul R. Jensen, and Bradley S. Moore* Chem. Bio. Chem., 2011, 12, 61-64. Doi: 10.1002/cbic.201000564.
Screening Natural Products for Inhibitors of Quinone Reductase-2 Using Ultrafiltration LC-MS. Yongsoo Choi, Katherine Jermihov, Sang-Jip Nam, Megan Sturdy, Katherine Maloney, Xi Qiu, Lucas R. Chadwick, Matthew Main, Shao-Nong Chen, Andrew D. Mesecar, Norman R. Farnsworth, Guido F. Pauli, William Fenical, John M. Pezzuto, and Richard R. van Breemen* Anal. Chem., 2011, 83, 1048-1052. doi: 10.1021/ac1028424.
Synthesis of an Urea-substituted Selenoisobutyric Acid Isostere of the Peroxisome Proliferator-activated Receptor α Selective Agonist. Hoosang Hwang, Hyukjae Choi, Sang-Jip Nam, Jaeyoung Ko, Jungyeob Ham, Jungwook Chin* and Heonjoong Kang* Bull. Korean Chem. Soc., 2011, 32, 4089-4091. Doi: 10.5012/bkcs.2011.32.11.4089.
[2006~2010]
Tuberatolides, Potent FXR Antagonists from the Korean Marine Tunicate Botryllus tuberatus. Hyukjae Choi, Hoosang Hwang, Jungwook Chin, Euno Kim, Jaehwan Lee, Sang-Jip Nam, Byoung Chan Lee, Boon Jo Rho, and Heonjoong Kang* J. Nat. Prod., 2010, 74, 90-94. doi: 10.1021/np100489u.
Selective Peroxisome Proliferator-activated Peceptor d Isosteric Selenium Agonists as Potent Anti-atherogenic Agents in vivo. Jungwook Chin, Jun Young Hong, Jaehwan Lee, Hoosang Hwang, Hyunsil Ko, Hyukjae Choi, Dongyup Hahn, Jaeyoung Ko, Sang-Jip Nam, Jungae Tak, Jungyeob Ham, Heonjoong Kang * Bioorg. Med. Chem. Lett., 2010, 20, 7239-7242. doi: 10.1016/j.bmcl.2010.10.103.
Fijiolides A and B, Inhibitors of TNF-a-Induced NFkB Activation, from a Marine-Derived Sediment Bacterium of the Genus Nocardiopsis. Sang-Jip Nam, Susana P. Gaudencio, Christopher A. Kauffman, Paul R. Jensen, Tamara P. Kondratyuk, Laura E. Marler, John M. Pezzuto, and William Fenical* J. Nat. Prod., 2010, 73, 1080-1086. doi: 10.1021/np100087c.
b-Carboline Alkaloids from a Korean Tunicate Eudistoma sp. Weihong Wang, Sang-Jip Nam, Byoung Chan Lee, and Heonjoong Kang* J. Nat. Prod., 2008, 71, 163-166. doi: 10.1021/np070064o.
Cooperation and Functional Diversification of Two Closely Related Galactolipase Genes for Jasmonate Biosynthesis. Youbonh Hyun, Sungwook Choi, Hyun-Ju Hwang, Jihyeon Yu, Sang-Jip Nam, Jaeyoung Ko, Ju-Young Park, Young Sam Seo, Eun Yu Kim, Stephen Beungtae Ryu, Woo Taek Kim, Yong-Hwan Lee, Heonjoong Kang, and Ilha Lee* Developmental Cell., 2008, 14, 183-192. doi: 10.1016/j.devcel.2007.11.010.
Scalarane Sesterterpenes from a Marine Sponge of the Genus of Spongia and Their FXR Antagonistic Activity. Sang-Jip Nam, Hyunsil Ko, Moon Kyeong Ju, Hoosang Hwang, Jungwook Chin, Jungyeob Ham, Byoung Chan Lee, Jaehwan Lee, Dong Hwan Won, Hyukjae Choi, Kyoungjin Shin, Taekyung Oh, Seokho Kim, Jung-Rae Rho and Heonjoong Kang* J. Nat. Prod., 2007, 70, 1691-1695. doi : 10.1021/np070024k.
Farnesoid X-activated receptor antagonists from a marine sponge Spongia sp. Sang-Jip Nam, Hyunsil Ko, Jungyeob Ham, Jungwook Chin, Mihee Shin, Youngshin Kim, Heeyoung Kim, Kyoungjin Shin, Hyukjae Choi, and Heonjoong Kang* Bioorg. Med. Chem. Lett.,2006, 16, 5398-5402. doi: 10.1016/j.bmcl.2006.07.079.
A Simple One-Pot Synthesis of Hydroxylated and Carboxylated Aryl Alkyl Sulfides from Various Bromobenzenes. Jaeyoung Ko, Jungyeob Ham, Inho Yang, Jungwook Chin, Sang-Jip Nam, and Heonjoong Kang* Tetrahedron Lett., 2006, 47, 7101-7106. doi: 10.1016/j.tetlet.2006.07.056.
• Patents
Jongchul Kim, Jungyeob Ham, Sang-Jip Nam, and Heonjoong Kang, “Development of Fluorescent Sensors for the PSP Toxins” KR (100753860), 2007. 08. 24.
Sang-Jip Nam, Hyunsil Ko, and Heonjoong Kang, “Pharmaceutical Composition, Health Food Composition and Farnesoid X-activated Receptor Inhibitors, Containing Scalarane-based Sesterterpenes” KR, 2006. 08. 03.
Sang-Jip Nam, Moon Kyeong Ju, and Heonjoong Kang, “Isolation and Purification Method of scalaranes and their Pharmaceutical Composition” KR, 2005. 01. 31.
Sang-Jip Nam, and Heonjoong Kang, “Isolation and Purification Method of Variabilin and its Use as a Sortase Inhibitor” KR, 2004. 07. 02.
Sang-Jip Nam, Heonjoong Kang, Hae-Jin Jeong, Jae Seong Kim, DongHwan Won, “Manufacturing Method of EPA and DHA from a Marine Dinoflagellate LingulodiniumPolyedra” KR, 2003. 06. 09.
• Symposia Presentations
Sang-Jip Nam, Christopher A. Kauffman, Paul R. Jensen, and William Fenical* “Actinoramides A–C, Highly Modified Peptides from a Marine Streptomyessp.” 52nd Annual Meeting, American Society of Pharmacognosy. San Diego, July 2011
Sang-Jip Nam, Kyoungjin Shin, Hyunsil Ko, Jaehwan Lee, Hoosang Hwang, Jingu Oh, Jungwook Chin, Jaeyoung Ko, and Heonjoong Kang, “Secondary Metabolites from a Korean Marine Sponge of the Genus Spongia and their Biological Activities” p288 the Korean Society of Oceanography, Busan, Korea, Spring, 2006.
Sang-Jip Nam, Moon Kyeong Ju, Dong Hwan Won, Mihee Shin, Jungwook Chin and Heonjoong Kang, “Discovery of scalarane sesterterpenes as FXR antagonists” Gordon Research Conference on Marine Natural Products, Venture Beach Marriott, Ventura, California, USA. February 26-March 3, 2006.
Sang-Jip Nam, Hoosang Hwang, Jaehwan Lee, Jingu Oh, Jaeyoung Ko, Jungyeob Ham, Jungwook Chin, Inho Yang, Kyoungjin Shin, Hyukjae Choi, and Heonjoong Kang, “Novel PPAR Agonists from an Unidentified Marine Sponge” 1st CMDD International Symposium on Marine Natural Products and Drug Discovery, The Shilla Seoul, Seoul, Korea. September 22-25, 2006.
Sang-Jip Nam, Moon Kyeong Ju, Dong Hwan Won, Mehee Sin, Heeyoung Kim, Youngshin Kim, and Heonjoong Kang, “FXR Antagonists from a Korean Marine Sponge” XI Symposium on Marine Natural Products, Sorrento, Italy. September 04-09, 2004.
Hyukjae Choi, Sang-Jip Nam, Heeyoung Kim, Soo-Hwan Kim, Ki-Bong Oh, and Heonjoong Kang, “Sortase Inhibitor from a Korean Marine Organism” XI Symposium on Marine Natural Products, Sorrento, Italy. September 04-09, 2004.
Dong Hwan Won, Sang-Jip Nam, Moon Kyeong Ju, and Heonjoong Kang, “Marine Natural Products, A Good Source for the Ligands of Nuclear Receptors Related with Metabolic Diseases” XI Symposium on Marine Natural Products, Sorrento, Italy, September 04-09, 2004.
Sang-Jip Nam, Heeyoung Kim, Youngshin Kim, Hyukjae Choi, Soo-Hwan Kim, Ki-Bong Oh, and Heonjoong Kang, “Antibacterial compounds from Korean marine sponges” 6th International Marine Biotechnology Conference and 5th Asia Pacific Marine Biotechnology Conference, Nippon Convention Center, Chiba, Japan. September 21-27, 2003.
Sang-Jip Nam, Heeyoung Kim, Youngshin Kim, Soo-Hwan Kim, Ki-Bong Oh, and Heonjoong Kang, “A Novel Anti-bacterial Compound of Scalarane Class Sesterterpene from a Korean Sponge” p145, the Korean Society of Oceanography, Ansan, Korea,Autumn, 2003.
Jongchul Kim, Jungyeob Ham, Sang-Jip Nam, and Heonjoong Kang, “Development of Fluorescent Sensors for the PSP Toxins” p111, the Korean Society of Oceanography, Ansan, Korea, Autumn, 2003.