Professor

Education

D.D.S.            Feb. 1998  Yonsei University College of Dentistry

M.S.                Feb. 2000  Department of Oral Biology, Yonsei University College of Dentistry

Ph.D.              Mar. 2008  Department of Biological Chemistry The Johns Hopkins University School of Medicine   

Appointments

2019- present   Professor, Department of Oral Biology, Yonsei University College of Dentistry

2018                  Visiting Scholar at UCSD

2014 – 2018      Associate professor, Department of Oral Biology, Yonsei University College of Dentistry

2009 – 2013      Assistant professor, Department of Oral Biology, Yonsei University College of Dentistry

2008                  Research instructor, Department of Oral Biology, Yonsei University College of Dentistry

2008                  Postdoctoral Fellow, Department of Biological Chemistry The Johns Hopkins University School of Medicine

1998 –1999       Research Assistant, Department of Oral Biology, Yonsei University College of Dentistry

Publications

Han SY, Cho SH, Kim SY, Seo JT, Moon SJ, Jhon GJ (1999) Monoacetyldiglycerides as new Ca2+ mobilizing agents in rat pancreatic acinar cells. Bioorg. Med. Chem. Lett. 9(1), 59-64

Kim YJ, Elliott AC, Moon SJ, Lee SI, Seo JT (1999) Octanol blocks fluid secretion by inhibition of capacitative calcium entry in rat mandibular salivary acinar cells. Cell Calcium 25(1):77-84

Kim CH, Kim JH, Moon SJ, Chung KC, Hsu CY, Seo JT, Ahn YS (1999) Pyrithione, a zinc ionophore, inhibits NF-kappaB activation. Biochem Biophys Res Commun. 259(3):505-9

Moon SJ, Ahn W, Lee MG, Kim H, Lee SI, Seo JT, Case RM, Kim KH (2000) A novel effect of rebamipide: generation of [Ca(2+)](i) oscillations through activation of CCK(1) receptors in rat pancreatic acinar cells. Eur J Pharmacol. 388(1):17-20

Kim CH, Kim JH, Moon SJ, Hsu CY, Seo JT, Ahn YS (2000) Biphasic effects of dithiocarbamates on the activity of nuclear factor-kappaB. Eur J Pharmacol. 392(3):133-6

Seo SR, Kim YJ, Moon SJ, Sugiya H, Shin DM, Lee SI, Seo JT (2003) Staurosporine-inhibitable protein kinase activity associated with secretory granule membranes isolated from rat submandibular gland cells. Arch Oral Biol. 48(8):553-8

Chong SA, Hong SY, Moon SJ, Park JW, Hong JH, An JM, Lee SI, Shin DM, Seo JT (2003) Partial inhibition of SERCA is responsible for extracellular Ca2+ dependence of AlF-4-induced [Ca2+]i oscillations in rat pancreatic. Am J Physiol Cell Physiol. 285(5):C1142-9

Moon SJ, An JM, Kim J, Lee SI, Ahn W, Kim KH, Seo JT (2004) Pharmacological characterization of rebamipide: its cholecystokinin CCK1 receptor binding profile and effects on Ca2+ mobilization and amylase release in rat pancreatic acinar cells. Eur J Pharmacol. 505(1-3):61-6

Hong JH, Moon SJ, Byun HM, Kim MS, Jo H, Bae YS, Lee SI, Bootman MD, Roderick HL, Shin DM, Seo JT (2006) Critical role of phospholipase Cgamma1 in the generation of H2O2-evoked [Ca2+]i oscillations in cultured rat cortical astrocytes. J Biol Chem. 281(19):13057-67

Moon SJ, Köttgen M, Jiao Y, Xu H, Montell C (2006) A taste receptor required for the caffeine response in vivo. Curr Biol. 16(18):1812-7

Jiao Y, Moon SJ, Montell C (2007) A Drosophila gustatory receptor required for the responses to sucrose, glucose, and maltose identified by mRNA tagging. Proc Natl Acad Sci U S A. 104(35):14110-5

Jiao Y, Moon SJ, Wang X, Ren Q, Montell C (2008) Gr64f is required in combination with other gustatory receptors for sugar detection in Drosophila. Curr Biol. 18(22):1797-801

Lee Y, Moon SJ, Montell C (2009) Multiple gustatory receptors required for the caffeine response in Drosophila. Proc Natl Acad Sci U S A. 106(11):4495-500.

Moon SJ, Lee YS, Jiao Y, Montell C. (2009) A Drosophila gustatory receptor essential for aversive taste and inhibiting male-to-male courtship. Curr. Biol. 19(19):1623-1627

Lee Y, Kang MJ, Shim J, Cheong CU, Moon SJ*, Montell C* (2012) Gustatory Receptors Required for Avoiding the Insecticide L-Canavanine. J Neuroscience. 32(4):1429-1435 (*corresponding author).

An JM, Wu HW, Kim HJ, Kim CH, Moon SJ (2012) Expression of Bitter Taste Receptors in Human Nasal Respiratory Epithelium. Int J Oral Biol. 37(2):57-62.

Jin HJ, An JM, Park J, Moon SJ*, Hong S* (2013) "Chemical-pain sensor" based on  nanovesicle-carbon nanotube hybrid structures. Biosens Bioelectron. 49:86-91 (*corresponding author).

Jeong YT, Shim J, Oh SR, Yoon HI, Kim CH, Moon SJ*, Montell C* (2013) An Odorant-Binding Protein Required for Suppression of Sweet Taste by Bitter Chemicals. Neuron 79(4):725-737 (*corresponding author).

Park J, Lee J, Shim J, Han W, Lee J, Bae YC, Chung YD, Kim CH, Moon SJ (2013) dTULP, the Drosophila melanogaster homolog of Tubby, regulates transient receptor potential channel localization in cilia. PLOS Genetics 9(9) (*corresponding author).

Mah YJ, Song JS, Kim SO, Lee JH, Jeon M, Jung UW, Moon SJ, Kim JH, Choi HJ (2014) The effect of epigallocatechin-3-gallate (EGCG) on human alveolar bone cells both in vitro and in vivo. Arch Oral Biol. 59(5):539-49. 

Kim JH, Jeon M, Song JS, Lee JH, Choi BJ, Jung HS, Moon SJ, DenBesten PK, Kim SO (2014). Distinctive genetic activity pattern of the human dental pulp between deciduous and permanent teeth. PLoS One. e102893. doi:10.1371/journal.pone.0102893

Lee Y*, Moon SJ*, Wang Y, Montell C (2015) A Drosophila gustatory receptor required for strychnine sensation. Chemical Senses 40(7);525-533 (*co-first author)

Shim J, Lee Y, Jeong YT, Kim Y, Lee MG, Montell C, Moon SJ (2015) The full repertoire of Drosophila gustatory receptors for detecting an aversive compound. Nature Communications 6,8867 doi: 10.1038/ncomms9867

Park J, Lee N, Kavoussi A, Seo JT, Kim CH, Moon SJ (2015) Ciliary phophoinositide regulates ciliary protein trafficking in Drosophila Cell Reports 13(12);2808-2816

Min S, Chae HS, Jang YH, Choi S, Lee S, Jeong YT, Jones WD, Moon SJ, Kim YJ, Chung J. (2016) Identification of peptidergic Pathway Critical to Satiety Responses in Drosophila. Curr Biol. 26(6):814-20.

Kang CM, Kim H, Song JS, Choi BJ, Kim SO, Jung HS, Moon SJ, Choi HJ (2016). Genetic Comparison of Stemness of Human Umbilical Cord and Dental Pulp. Stem Cells Int. 3453890. doi: 10.1155/2016/3453890.

Kim K, Jeon M, Lee HS, Park JC, Moon SJ, Kim SO, Cho SW, Song JS. (2016) Comparative analysis of secretory factors from permanent- and deciduous-teeth periodontal ligament cells. Arch Oral Biol. 71:65-79.

Jeong YT, Oh SM, Shim J, Seo JT, Kwon JY, Moon SJ (2016) Mechanosensory neurons control sweet sensing in Drosophila. Nat Commun. 7:12872.

Yoon EJ, Jeong YT, Lee JE, Moon SJ*, Kim CH. (2017) Tubby domain superfamily protein is required for the formation of the 7S SNARE complex in Drosophila. Biochem Biophys Res Commun. 482(4):814-820. (*corresponding author)

Kim H, Jeong YT, Choi MS, Choi J, Moon SJ*, Kwon JY* (2017) Involvement of a Gr2a-Expressing Drosophila Pharyngeal Gustatory Receptor Neuron in Regulation of Aversion to High-Salt Foods. Mol Cells. doi: 10.14348/molcells.2017.0028. (*corresponding author)

Sung HY, Jeong YT, Lim JY, Kim H, Oh SM, Hwang SW, Kwon JY, Moon SJ. (2017) Heterogeneity in the Drosophila gustatory receptor complexes that detect aversive compounds. Nat Commun. 8(1):1484.

Kim H, Kim H, Kwon JY, Seo JT, Shin DM, Moon SJ (2018) Drosophila Gr64e mediates fatty acid sensing via the phospholipase C pathway. PLoS Genet. 8;14(2)

Lee N, Park J, Bae YC, Lee JH, Kim CH, Moon SJ (2018). Time-Lapse Live-Cell Imaging Reveals Dual Function of Oseg4, Drosophila WDR35, in Ciliary Protein Trafficking. Mol Cells 41(7):676-683

Kim J, Kim H, Noh SH, Jang DG, Park SY, Min D, Kim H, Kweon HS, Kim H, Aum S, Seo S, Choi CS, Kim H, Kim JW, Moon SJ, Gee HY, Lee MG. (2020) Grasp55-/- mice display impaired fat absorption and resistance to high-fat diet-induced obesity. Nat Commun. 11(1):1418

Han W, Shin JO, Ma JH, Min H, Jung J, Lee J, Kim UK, Choi JY, Moon SJ, Moon DW, Bok J, Kim CH. (2020) Distinct roles of stereociliary links in the nonlinear sound processing and noise resistance of cochlear outer hair cells. Proc Natl Acad Sci 19;117(20):11109-11117. 

Kim SJ, Jeong YT, Jeong SR, Park M, Go HS, Kim MY, Seong JK, Kim KW, Seo JT, Kim CH, Lee JH, Moon SJ. (2020) Neural regulation of energy and bone homeostasis by the synaptic adhesion molecule Calsyntenin-3. Exp Mol Med. 52(5):793-803.

Kim SJ, Piao Y, Lee MG, Han AR, Kim K, Hwang CJ, Seo JT, Moon SJ. (2020) Loss of Sirtuin 6 in osteoblast lineage cells activates osteoclasts, resulting in osteopenia. Bone. 138:115497. 

Chae D, Lee J, Lee N, Park K, Moon SJ*, Kim HH. (2020) Chemical Controllable Gene Drive in Drosophila. ACS Synth Biol. 18;9(9):2362-2377. (*corresponding author)

Cho B, Yoon SH, Lee D, Koranteng F, Tattikota SG, Cha N, Shin M, Do H, Hu Y, Oh SY, Lee D, Vipin Menon A, Moon SJ, Perrimon N, Nam JW, Shim J. (2020) Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila. Nat Commun. 11(1):4483.

Oh SM, Jeong K, Seo JT, Moon SJ (2021) Multisensory interactions regulate feeding behavior in Drosophila. Proc Natl Acad Sci U S A. 118(7):e2004523118.