Research

CURRENT RESEARCH INTERESTS

  • Transcriptional regulation of energy metabolism

  • Transcriptional regulation of brown fat (BAT) development

  • Epigenetics

  • Biology on energy metabolism and brown fat development traditional Chinese medicine derived natural products

  • Phosphoproteomic analysis of traditional Chinese medicine derived natural products

  • Molecular endocrinology

  • Molecular basis of metabolic diseases: metabolic syndromes, obesity, diabetes and NAFLD

  • Biological applications of novel peptidomimetic for biomarker and antigen discovery

  • Cancer immunology

  • ROS signaling and inflammatory response

RESEARCH GRANTS

As a PI:

  • Differential functional phosphoproteomic analysis of cancer cells with triptolide or celastrol treatment. Seed funding for basic research project, HKU, 2014

  • Global phosphoproteomic examination of immunomodulatory effect of analogues of anti-cancer compound Fumagillin analogues. Seed funding for basic research project, HKU, 2015

  • Role of USF methylation and epigenetic modifications in lipogenic gene repression during starvation. GRF, RGC, 2016, HKD $1,259,110

    • As a Co-I:

  • Functional and comparative phosphoproteomic analysis of cancer cells treated with anticancer natural products triptolide and celastrol. GRF, RGC, 2015, HKD $1,007,74

EDITORIAL BOARD