3. Publications

26. Xue W, Lee D, Kong Y, Kuss M, Huang Y, Kim T, Chung S, Dudley A, Ro SH*, Duan B*. (2023) A Facile Strategy for the Fabrication of Cell-laden Porous Alginate Hydrogels Based on Two-phase Aqueous Emulsions. Advan Funct Mater., doi.org/10.1002/adfm.202214129, *Corresponding authors [pdf]

25. Ro SH*, Bae J, Jang Y, Myers JF, Chung S, Yu J, Natarajan SK, Franco R, Song HS. (2022) Arsenic Toxicity on Metabolism and Autophagy in Adipose and Muscle Tissues. Antioxidants (Basel), 11(4) : 689, *Corresponding author [Pubmed]

24. Liu B, LiZ, Yu H, Shi X, Zhou Y, Alvarez S, Naldrett MJ, Kachman SD, Ro SH, Sun x, Chung S, Jing L, Yu J. (2021) Therapeutic potential of garlic chive-derived vesicle-like nanoparticles in NLRP3 inflammasome-mediated inflammatory diseases. Theranostics, 11 : 9311-9330 [Pubmed]

23. Ro SH*, Fay J, Cyuzuzo CI, Jang Y, Lee N, Song HS, Harris EN. (2020) SESTRINs: Emerging Dynamic Stress-Sensors in Metabolic and Environmental Health. Front Cell Dev Biol., 8 : 603421, *Corresponding author [Pubmed]

22. Kim H, Jeon BT, Kim IM, Bennett SJ, Lorch CM, Viana MP, Myers JF, Trupp CJ, Whipps ZT, Kundu M, Chung S, Sun X, Khalimonchuk O, Lee J, Ro SH*. (2020) Sestrin2 phosphorylation by ULK1 induces autophagic degradation of mitochondria damaged by copper-induced oxidative stress. Int J Mol Sci., 21 : E6130, *Corresponding author [Pubmed]

21. Kim M*, Sujkowski A*, Namkoong S, Gu B, Cobb T, Kim B, Kowalski AH, Cho CS, Semple I, Ro SH, Davis C, Brooks S, Karin M, Wessells RJ, Lee JH. (2020) Sestrins are evolutionarily conserved mediators of exercise benefits. Nature Commun., 11:190, *Co-first authors [Pubmed]

20. Bae J, Jang Y, Kim H, Mahato K, Schaecher C, Kim IM, Kim E, Ro SH*. (2019) Arsenite exposure suppresses adipogenesis, mitochondrial biogenesis and thermogenesis via autophagy inhibition in brown adipose tissue. Sci. Rep., 9 : 14464, *Corresponding author [Pubmed]

19. Ro SH*, Jang Y, Bae J, Kim IM, Schaecher C, Shomo ZD. (2019) Autophagy in adipocyte browning: Emerging drug target for the intervention of obesity. Front Physiol., 10 : 22, *Corresponding author [PubMed]

18. Fan R, Toney A, Jang Y, Ro SH, Chung S. (2018) Maternal n-3 PUFA supplementation promotes fetal brown adipose tissue development through epigenetic modifications in C57BL/6 mice. Biochim Biophys Acta Mol Cell Biol Lipids, 1863 : 1488-1497 [PubMed]

17. Ro SH*, Xue X*, Ramakrishnan SK, Cho CS, Namkoong S, Jang I, Semple IA, Ho A, Park HW, Shah YM, Lee JH. (2016) Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis. Elife, 5 : e12204, *Co-first authors [PubMed]

16. Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, Schulman BA, Xu J, Semple I, Ro SH, Kim B, Mavioglu RN, Tolun A, Jipa A, Takats S, Karpati M, Li JZ, Yapici Z, Juhasz G, Lee JH, Klionsky DJ, Burmeister M. (2016) Mutations in ATG5 reduces autophagy and leads to ataxia with developmental delay. Elife, 5 : e12245 [PubMed]

15. Kim H*, An S*, Ro SH*, Teixeira FP, Park GJ, Kim C, Cho CS, Kim JS, Jakob U, Lee JH and Cho US. (2015) Janus-faced Sestrin2 controls ROS and mTOR signaling through two separate functional domains. Nature Commun., 6 : 10025, *Co-first authors [PubMed]

14. Ro SH, Semple I, Ho A, Park HW, Lee JH. (2015) Sestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose Tissue. Front Endocrinol. (Lausanne), 6 : 114 [PubMed]

13. Kim M, Semple I, Kim B, Kiers A, Nam S, Park HW, Park H, Ro SH, Kim JS, Juhasz G, and Lee JH. (2015) Drosophila Gyf/GRB10 interaction GYF protein is an autophagy regulator that controls neuron and muscle homeostasis. Autophagy, 11 : 1358-1372 [PubMed]

12. Kim JS*, Ro SH*, Kim M, Park HW, Semple IA, Park H, Cho US, Wang W, Guan KL, Karin M, Lee JH. (2015) Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Sci Rep., 5 : 9502, *Co-first authors [PubMed]

11. Park HW, Park H, Semple IA, Jang I, Ro SH, Kim M, Cazares VA, Stuenkel EL,Kim JJ, Kim JS, Lee JH. (2014) Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers. Nature Commun., 5 : 4834 [PubMed]

10. Ro SH, Semple IA, Park H, Park HL, Park HW, Kim M, Kim JS, Lee JH. (2014) Sestrin2 Promotes Unc-51-like Kinase 1 Mediated Phosphorylation of p62/sequestosome-1. FEBS J., 281 : 3816-3827 [PubMed]

9. Park HW, Park HL, Ro SH, Jang I, Semple IA, Kim DN, Kim M, Nam M, Zhang D, Yin L, Lee JH. (2014) Hepatoprotective role of Sestrin2 against chronic ER stress. Nature Commun., 5 : 4233 [PubMed]

8. Ro SH, Nam M, Jang I, Park HW, Park HL, Semple IA, Kim M, Kim JS, Park H, Einat P, Damari G, Golikov M, Feinstein E, Lee JH. (2014) Sestrin2 inhibits uncoupling protein 1 expression through suppressing reactive oxygen species. Proc Natl Acad Sci USA., 111 : 7849-7854 [PubMed]

7. Ro SH*, Jung CH*, Hahn WS, Xu X, Kim YM, Yun YS, Park JM, KH Kim, Seo M, TY Ha, Arriaga EA, Bernlohr DA, Kim DH. (2013) Distinct functions of ULK1 and ULK2 in the regulation of lipid metabolism in adipocytes. Autophagy, 9 : 2103-2114, *Co-first authors [PubMed]

6. Kim M, Park HL, Park HW, Ro SH, Nam SG, Reed JM, Guan JL, Lee JH. (2013) Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging. Autophagy, 9 : 1201-1213 [PubMed]

5. Ro SH, Liu D, Yeo H, Paik JH. (2013) FoxOs in neural stem cell fate decision. Arch Biochem Biophys., 534 : 55-63 [PubMed]

4. Jung CH, Ro SH, Cao J, Otto NM, Kim DH. (2010) mTOR regulation of autophagy. FEBS Lett., 584 :1287-1295 [PubMed]

3. Bandhakavi S*, Kim YM*, Ro SH*, Xie H, Onsongo G, Jun CB, Kim DH, Griffin TJ. (2010) Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response. Mol Cell Proteomics, 9 : 403-414 , *Co-first authors [PubMed]

2. Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, Kundu M, Kim DH. (2009) ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell., 20 : 1992-2003 [PubMed]

1. Ro SH, Ha NC. (2007) High-level production and initial crystallization of a Fe65 domain. J of Life Sci., 17 : 18-23 [pdf]