Publications
Seckinger KM, Rao VP, Snell NE, Mancini AE, Markwardt ML, Rizzo MA. Nitric Oxide Activates β-Cell Glucokinase by Promoting Formation of the “Glucose-Activated” State. Biochemistry. 2018; 57(34) 5136-5144. doi:10.1021/acs.biochem.8b00333. PubMed PMID: 30053375.
Markwardt ML, Snell NE, Guo M, Wu Y, Christensen R, Liu H, Shroff H, Rizzo MA. A Genetically Encoded Biosensor Strategy for Quantifying Non-muscle Myosin II Phosphorylation Dynamics in Living Cells and Organisms. Cell Rep. 2018; 24(4) 1060-1070.e4. doi:10.1016/j.celrep.2018.06.088. PubMed PMID: 30044973. PMCID: PMC6117825.
Ross BL, Tenner B, Markwardt ML, Zviman A, Shi G, Kerr JP, Snell NE, Mcfarland JJ, Mauban JR, Ward CW, Rizzo MA, Zhang J. Single-color, ratiometric biosensors for detecting signaling activities in live cells. Elife. 2018; 7 1569-1583. doi:10.7554/eLife.35458. PubMed PMID: 29968564. PMCID: PMC6037473.
Markwardt ML, Seckinger KM, Rizzo MA. Regulation of Glucokinase by Intracellular Calcium Levels in Pancreatic Beta Cells. J Biol Chem. 291: 3000-3009 2016. PMID: 26698632
Desmond PF, Muriel J, Markwardt ML, Rizzo MA, Bloch RJ. Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle. J Biol Chem 290(46):27854-67 2015 PMID: 26405035
Costantini LM, Baloban M, Markwardt ML, Rizzo M, Guo F, Verkhusha VV, Snapp EL. A palette of fluorescent proteins optimized for diverse cellular environments. Nat Commun. 6:7670 2015 PMID: 26158227
Fairfax ST, Mauban JR, Hao S, Rizzo MA, Zhang J, Wier WG. Ca(2+) signaling in arterioles and small arteries of conscious, restrained, optical biosensor mice. Front Physiol. 5:387 2014. PMID: 25339912
Mauban JR, Fairfax ST, Rizzo MA, Zhang J, Wier WG. A method for noninvasive longitudinal measurements of [Ca2+] in arterioles of hypertensive optical biosensor mice. Am J Physiol Heart Circ Physiol. 307:H173-81 2014. PMID: 24858846
Merrins MJ, Van Dyke AR, Mapp AK, Rizzo MA, Satin LS. Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity. J Biol Chem. 288:33312-22. 2013. PMID: 24100037
Watkins JL, Kim H, Markwardt ML, Chen L, Fromme R, Rizzo MA, & Wachter RM. The 1.6 Å resolution structure of a FRET-optimized Cerulean fluorescent protein. Acta Crystallogr D Biol Crystallogr. 69:767-73. 2013. PMID: 23633585
Haataja L, Snapp E, Wright J, Liu M, Hardy AB, Wheeler MB, Markwardt ML, Rizzo M, & Arvan P. Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cells. J Biol Chem. 288:1896-906. 2013 PMID: 23223446
Markwardt ML, Nkobena A, Ding SY, & Rizzo MA. Association with nitric oxide synthase on insulin secretory granules regulates glucokinase protein levels. Mol Endocinol. 26:1617-29. 2012. PMID: 22771492
Geraedts MC, Takahashi T, Vigues S, Markwardt ML, Nkobena A, Cockerham RE, Hajnal A, Dotson CD, Rizzo MA & Munger SD. Transformation of post-ingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery. Am J Physiol Endocrinol Metab. 303:E464-72. 2012. PMCID: PMC3423100
Gade P, Ramachandran G, Maachani UB, Rizzo MA, Okada T, Prywes R, Cross AS, Mori K & Kalvakolanu DV. A novel IFN-γ-stimulated ATF6/C/EBP-β signaling pathway critical for the expression of DAPK 1 and induction of autophagy. Proc. Natl. Acad. Sci. USA 109:10316-21. 2012. PMCID: PMC3387052
Ding SY, Nkobena A, Kraft CA, Markwardt ML & Rizzo MA. Glucagon-like peptide 1 stimulates post-translational activation of glucokinase in pancreatic beta cells J. Biol. Chem. 286:16768-42. 2011. PMCID: PMC3089519
Markwardt ML, Kremers GK, Kraft CA, Ray K, Cranfill PJC, Wilson KA, Day RN, Wachter RM, Davidson MW & Rizzo MA. An improved Cerulean Fluorescent protein with enhanced brightness and reduced reversible photoswitching PLoS ONE 6:e17896. 2011. PMCID: PMC3066204
Ding SY, Tribble ND, Kraft CA, Markwardt M, Gloyn AL & Rizzo MA. Naturally occurring glucokinase mutations are associated with defects in post-translational S-nitrosylation. Mol Endocrinol. 24:171-7. 2010. PMCID: PMC2802892
Rizzo MA. & Piston D.W. FRET by Fluorescence Polarization Microscopy Sullivan K.F. (ed). Methods in Cell Biology. 85:415-30. 2008.
Malo GD, Pouwels LJ, Wang M, Rizzo MA, Piston DW & Wachter RM. Structural basis of a reduced excited state heterogeneity in Cerulean GFP: A tryptophan-based chromophore with optimized hydrogen bonding interactions. Biochemistry 46:9865-73. 2007.
Rizzo MA, Springer G, Segawa K, Zipfel W & Piston DW. Optimization of pairings and detection conditions for measurement of FRET between cyan and yellow fluorescent proteins. Microscopy & Microanalysis 12:238-54. 2006.
Rizzo MA & Piston DW. A High Contrast Method for Imaging FRET between Fluorescent Proteins. Biophys J. 88:L14-16. 2005 PMCID:PMC1305173
Rizzo MA. Springer GH, Granada B & Piston D. W. An improved cyan fluorescent protein variant useful for FRET. Nat. Biotechnol. 22:445-49. 2004. PMID:14990965
Rizzo MA & Piston DW. Regulation of β-cell glucokinase by S-nitrosylation and association with nitric oxide synthase. J. Cell Biol. 161:243-48. 2003. PMID:12707306
Rizzo MA, Shome K, Vasudevan C, Stolz DB, Sung TC, Frohman MA, Watkins SC & Romero G. Phospholipase D and its product phosphatidic acid mediate agonist-dependent Raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway. J. Biol. Chem. 274:1131-39. 1999. PMID: 9873061
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