Invest Clin 65 (2) 2024

Surgical complications in children with IgA vasculitis: clinical analysis of 28 cases.  (Complicaciones quirúrgicas en niños con vasculitis IgA: análisis clínico de 28 casos. ) Jing Mu, Jing Hao, Xiaofang Zhen, Xin Mo, Yan Sheng.  E-mail: bchhaojing@163.com.    Department of Traditional Chinese Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing,China.  Invest Clin 65(2): 134 - 142, 2024 https://doi.org/10.54817/IC.v65n2a01 

Beneficial effects of gentiopicrin inhibiting experimental epilepsy in young rats through the P2X7R/NLRP3/Caspase-1 inflammatory pathway.  (Efectos inhibitorios de la gentiopicrina sobre la epilepsia experimental en ratas jóvenes mediante la vía inflamatoria P2X7R/NLRP3/Caspasa-1. ) Jia Lin Li1 , Lin Huang2 ,Xing Jun Wu3 , Min Ye3 and Chuan Yong Yu2. . E-mail: yuchuanyongsub@yeah.net    1.- Department of Medicine, Tongling Polytechnic. Tongling, China. 2.- Department of Neurology, Nanjing Brian Hospital affiliated to Nanjing Medical University, Nanjing, China. 3.- Department of Neurology, the Affiliated Ben Q Hospital of Nanjing Medical University, Nanjing, China.   Invest Clin 65(2): 143 - 154, 2024 https://doi.org/10.54817/IC.v65n2a02 

Benefits of a modified local precision liver resection using intraoperative laparoscopic ultrasound in the treatment and prognosis of patients with liver cancer.  (Beneficios de la resección hepática de precisión local modificada, utilizando ecografía intraoperatoria laparoscópica en el tratamiento y pronóstico de pacientes con cáncer de hígado. )  Yansong Xu1 and Lin Shen2  E-mail: tonggubu9822@163.com   1.- Department of Hepatobiliary Surgery, Affiliated Hospital of Beihua University, Jilin, China. 2.-  Department of Anesthesiology, Affiliated Hospital of Beihua University, Jilin, China.  Invest Clin 65(2): 155 - 168, 2024 https://doi.org/10.54817/IC.v65n2a03 

Genetic association study of the rs10774671 variant of the OAS1 gene with the severity of COVID-19 in an Ecuadorian population.  (Estudio de asociación genética de la variante rs10774671 del gen OAS1 con la severidad de COVID-19 en una población ecuatoriana. )  Kathya Pilataxi1 , Thalía Balarezo1 , Erik Chávez, Camila Acosta1 , Ivonne Z. Peña2 , Katherin Narváez2 and Francisco Álvarez-Nava1. E-mail: fjalvarez@uce.edu.ec  1.-  Facultad de Ciencias Biológicas, Universidad Central del Ecuador, Quito, Ecuador. 2.-  Hospital Quito Sur del Instituto Ecuatoriano de Seguridad Social, Quito, Ecuador.  Invest Clin 65(2): 169 - 178, 2024 https://doi.org/10.54817/IC.v65n2a04 

Insulin-like growth factor-1 promotes the proliferation and odontogenic differentiation of human dental pulp cells in vitro and in vivo.  (El factor de crecimiento similar a la insulina-1 promueve la proliferación y diferenciación odontogénica de células de pulpa dental humana in vitro e in vivo )  Yan Wang, Nan Du, Cong-na Liu and Wen-jing Li.  . E-mail: 27801072@hebmu.edu.cn   Department of Oral Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, China.   Invest Clin 65(2): 179 - 191, 2024 https://doi.org/10.54817/IC.v65n2a05 

Gender-based comparative analysis of knee injury risk during cutting maneuvers in non-professional athletes: a kinetic and kinematic perspective.  (Análisis comparativo, basado en el género, del riesgo de lesión de rodilla durante cambios de dirección en atletas no profesionales: una perspectiva cinética y cinemática. )  Adrián Feria-Madueño1 , Timothy E. Hewett2,3 and Borja Sañudo1. E-mail: aferia1@us.es    1.- Department of Physical Education and Sport, University of Seville. Pirotecnia Street, Seville, Spain. 2.- Department of Orthopedics, Marshall University Biomechanics Laboratories and Sports Medicine Research, Marshall University, Huntington, West Virginia, USA. 3.- Hewett Global Consulting, Newport, KY.   Invest Clin 65(2): 192 - 205, 2024 https://doi.org/10.54817/IC.v65n2a06 

The effectiveness of personalized medication based on drug-related genes, for schizophrenia patients with resistance to traditional drugs.  (La eficacia de la medicación personalizada basada en genes relacionados con fármacos, para pacientes con esquizofrenia resistente a los fármacos tradicionales. )   Shujun Zhou1, Guangqin Zhang2, Zhe Wang3 , Long Wei1 , Min Zhu4 , Jinquan He5. E-mail: zhumin2023@sina.com   1.- Department of Pharmacy，Nanjing Gaochun People’s Hospital，Nanjing, Jiangsu, China. 2.- Department of Pharmacy, Ezhou Central Hospital, Ezhou, Hubei, China. 3.- Department of Pharmacy，Medical Supplies Center of PLA General Hospital，Beijing, China. 4.- Department of Pharmacy，The Affiliated Taizhou People’s Hospital of Nanjing Medical University，Taizhou Jiangsu，China. 5.- Department of Psychosomatic Medicine, Chenzhou First People’s Hospital, Chenzhou, Hunan, China.  They contributed equally to this work.  Invest Clin 65(2): 206 - 219, 2024 https://doi.org/10.54817/IC.v65n2a07 

Effect of thiamine pyrophosphate on oxidative damage in the brain and heart of rats with experimentally induced occlusion of the common carotid artery.  (Efecto del pirofosfato de tiamina sobre el daño oxidativo en el cerebro y el corazón de ratas con oclusión inducida experimentalmente de la arteria carótida común. )  Izzet Emir1 , Zeynep Suleyman2 and Halis Suleyman3.  E-mail: halis.suleyman@gmail.com   1.- Department of Cardiovascular Surgery, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan/Türkiye. 2.- Department of Nursing, Faculty of Health Sciences, Erzincan Binali Yildirim University, Erzincan/Türkiye. 3.- Department of Pharmacology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan/Türkiye.   Invest Clin 65(2): 220 - 229, 2024 https://doi.org/10.54817/IC.v65n2a08 

Mechanisms of programmed cell death: structural and functional pathways. A narrative review.  (Mecanismos de muerte celular programada: vías estructurales y funcionales. Una revisión narrativa. )  Diego Fernández-Lázaro1,2,3,Begoña Sanz4,5 and Jesús Seco-Calvo3,4,6.  E-mail: diego.fernadez.lazaro@uva.es   1.- Department of Cellular Biology, Genetics, Histology and Pharmacology, Faculty of Health Sciences, University of Valladolid, Campus of Soria, Soria, Spain. 2.- Neurobiology Research Group, Faculty of Medicine, University of Valladolid, Valladolid, Spain. 3.- SARCELLOMICS® Research Group, León, Spain. 4.- Department of Physiology, University of the Basque Country, Leioa, Spain. 5.- Biocruces Bizkaia Health Research Institute, Barakaldo Spain. 6.- Institute of Biomedicine, University of León, León, Spain.   Invest Clin 65(2): 230 - 252, 2024 https://doi.org/10.54817/IC.v65n2a09 

Valor de la 18F-FDG-PET/CT en la estadificación inicial de pacientes con cáncer de tiroides de moderado/alto riesgo con subtipos histológicos agresivos.  (Value of the 18F-FDG-PET/CT in the initial staging of patients with high-risk thyroid cancer with aggressive histological subtypes. )  Luis Felipe Colmenter1,2,3, Sunil Daryanani4 , Sergio Zúñiga5 y Javier Vilar6.  Correo electrónico: luiscolmenter@hotmail.com  1.- Universidad del Zulia. Maracaibo. Venezuela. 2.- Universidad de Sao Paulo, Sao Paulo, Brasil. 3.- Pontificia Universidad Javeriana de Cali. Cali, Colombia. 4.- Universidad Central de Venezuela. Caracas, Venezuela. 5.- Hospital de la Universidad Nacional de Colombia. Bogotá, Colombia. 6.- Universidad de Montevideo. Montevideo. Uruguay