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Major research themes
Major research themes
- Development of novel genome editing tools in bacteria, yeast, microalgae, and plants.
- CRISPR/Cas-based targeted random mutagenesis for mimicking crop evolution in a fast-forward manner.
Protocol for assessment of CRISPR base editors and their components in Escherichia coli.
STAR protocols 6 (3):103973, September 2025. DOI: https://doi.org/10.1016/j.xpro.2025.103973 [PDF]
Improved dual base editing systems (iACBEs)
Improved dual base editor systems (iACBEs) for simultaneous conversion of adenine and cytosine in the bacterium Escherichia coli. mBio (ASM, American Society for Microbiology) 14 (1): e02296-22, January 2023. DOI: https://doi.org/10.1128/mbio.02296-22 [PDF]
CRISPR/Cas-mediated generation of biotic stress (pathogen)-resistant tomatoes
CRISPR/Cas9-mediated generation of pathogen-resistant tomato against Tomato yellow leaf curl virus and powdery mildew. International Journal of Molecular Sciences 22:1878, February 2021. DOI: https://doi.org/10.3390/ijms22041878 [PDF]
Engineering drought and salinity tolerance traits in crops through CRISPR (Literature Review)
Engineering drought and salinity tolerance traits in crops through CRISPR-mediated genome editing: Targets, tools, challenges, and perspectives. Plant Communications 3 (6):100417. November 2022. DOI: https://doi.org/10.1016/j.xplc.2022.100417 [PDF]
Platform established for novel GE tool assessment in bacteria and plant
IRI-CCE: In vivo Rapid Investigation of CRISPR Components in Escherichia coli
In vivo rapid investigation of CRISPR-based base editing components in Escherichia coli (IRI-CCE): a platform for evaluating base editing tools and their components. International Journal of Molecular Sciences 23 (3):1145, January 2022. DOI: https://doi.org/10.3390/ijms23031145 [PDF])
CRISPR-mediated engineering across the central dogma (Literature Review)
CRISPR-mediated engineering across the central dogma in plant biology for basic research and crop improvement. Molecular Plant 14:1-24, January 2021. DOI: https://doi.org/10.1016/j.molp.2020.11.002 [PDF]
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