Publications

2019

Drury ER, Friedman DJ, Pollak MR, Ix JH, Kuller LH, Tracy RP, Mukamal KJ. APOL1 gene variants and kidney disease in whites: the cardiovascular health study. Nephrol Dial Transplant. 2019 Dec 01; 34(12):2155-2156. PMID: 31580460.

Friedman DJ, Pollak MR. APOL1 and Kidney Disease: From Genetics to Biology. Annu Rev Physiol. 2019 Nov 11. PMID: 31710572.

Shao H, Wingert B, Weins A, Pollak MR, Camacho C, Wells A. Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations. Sci Rep. 2019 Oct 29; 9(1):15517. PMID: 31664084.

Shah SS, Lannon H, Dias L, Zhang JY, Alper SL, Pollak MR, Friedman DJ. APOL1 Kidney Risk Variants Induce Cell Death via Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore. J Am Soc Nephrol. 2019 Dec; 30(12):2355-2368. PMID: 31558683.

Drury ER, Stillman IE, Pollak MR, Denker BM. Autosomal Recessive Alport Syndrome Unveiled by Pregnancy. Nephron. 2019; 143(4):288-292. PMID: 31408864.

Lannon H, Shah SS, Dias L, Blackler D, Alper SL, Pollak MR, Friedman DJ. Apolipoprotein L1 (APOL1) risk variant toxicity depends on the haplotype background. Kidney Int. 2019 Dec; 96(6):1303-1307. PMID: 31611067.

Wang M, Chun J, Genovese G, Knob AU, Benjamin A, Wilkins MS, Friedman DJ, Appel GB, Lifton RP, Mane S, Pollak MR. Contributions of Rare Gene Variants to Familial and Sporadic FSGS. J Am Soc Nephrol. 2019 Sep; 30(9):1625-1640. PMID: 31308072.

Riella C, Siemens TA, Wang M, Campos RP, Moraes TP, Riella LV, Friedman DJ, Riella MC, Pollak MR. APOL1-Associated Kidney Disease in Brazil. Kidney Int Rep. 2019 Jul; 4(7):923-929. PMID: 31317114.

Chun J, Zhang JY, Wilkins MS, Subramanian B, Riella C, Magraner JM, Alper SL, Friedman DJ, Pollak MR. Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity. Proc Natl Acad Sci U S A. 2019 Feb 26; 116(9):3712-3721. PMID: 30733285.

Poyan Mehr A, Sadeghi-Najafabadi M, Chau K, Messmer J, Pai R, Roy N, Friedman D, Pollak MR, Schlondorff J, Naljayan M, Singh T, Lecker SH, Rodby R, Germain M, Rennke H, Stillman IE. The Glomerular Disease Study and Trial Consortium: A Grassroots Initiative to Foster Collaboration and Innovation. Kidney Int Rep. 2019 Jan; 4(1):20-29. PMID: 30596165.

2018

Franceschini N, Kopp JB, Barac A, Martin LW, Li Y, Qian H, Reiner AP, Pollak M, Wallace RB, Rosamond WD, Winkler CA. Association of APOL1 With Heart Failure With Preserved Ejection Fraction in Postmenopausal African American Women. JAMA Cardiol. 2018 Aug 01; 3(8):712-720. PMID: 29971324.

Fan Y, Liu W, Bi R, Densmore MJ, Sato T, Mannstadt M, Yuan Q, Zhou X, Olauson H, Larsson TE, Toka HR, Pollak MR, Brown EM, Lanske B. Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3749-E3758. PMID: 29618612.

Zhang JY, Wang M, Tian L, Genovese G, Yan P, Wilson JG, Thadhani R, Mottl AK, Appel GB, Bick AG, Sampson MG, Alper SL, Friedman DJ, Pollak MR. UBD modifies APOL1-induced kidney disease risk. Proc Natl Acad Sci U S A. 2018 03 27; 115(13):3446-3451. PMID: 29531077.

Skorecki KL, Lee JH, Langefeld CD, Rosset S, Tzur S, Wasser WG, Shemer R, Hawkins GA, Divers J, Parekh RS, Li M, Sampson MG, Kretzler M, Pollak MR, Shah S, Blackler D, Nichols B, Wilmot M, Alper SL, Freedman BI, Friedman DJ. A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy. Nephrol Dial Transplant. 2018 Feb 01; 33(2):323-330. PMID: 28339911.

Feng D, Notbohm J, Benjamin A, He S, Wang M, Ang LH, Bantawa M, Bouzid M, Del Gado E, Krishnan R, Pollak MR. Disease-causing mutation in a-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):1517-1522. PMID: 29378953.

Feng D, DuMontier C, Pollak MR. Mechanical challenges and cytoskeletal impairments in focal segmental glomerulosclerosis. Am J Physiol Renal Physiol. 2018 May 01; 314(5):F921-F925. PMID: 29363327.

2017

Pollak MR. Introduction: APOL1-Associated Kidney Disease. Semin Nephrol. 2017 11; 37(6):489. PMID: 29110755.

Gucalp A, Iyengar NM, Zhou XK, Giri DD, Falcone DJ, Wang H, Williams S, Krasne MD, Yaghnam I, Kunzel B, Morris PG, Jones LW, Pollak M, Laudone VP, Hudis CA, Scher HI, Scardino PT, Eastham JA, Dannenberg AJ. Periprostatic adipose inflammation is associated with high-grade prostate cancer. Prostate Cancer Prostatic Dis. 2017 12; 20(4):418-423. PMID: 28653675.

Sato T, Courbebaisse M, Ide N, Fan Y, Hanai JI, Kaludjerovic J, Densmore MJ, Yuan Q, Toka HR, Pollak MR, Hou J, Lanske B. Parathyroid hormone controls paracellular Ca2+ transport in the thick ascending limb by regulating the tight-junction protein Claudin14. Proc Natl Acad Sci U S A. 2017 04 18; 114(16):E3344-E3353. PMID: 28373577.

Wang H, Pun PH, Kwee L, Craig D, Haynes C, Chryst-Ladd M, Svetkey LP, Patel UD, Hauser ER, Pollak MR, Kraus WE, Shah SH. Apolipoprotein L1 Genetic Variants Are Associated with Chronic Kidney Disease but Not with Cardiovascular Disease in a Population Referred for Cardiac Catheterization. Cardiorenal Med. 2017 Feb; 7(2):96-103. PMID: 28611783.

2016

Feng D, Steinke JM, Krishnan R, Birrane G, Pollak MR. Functional Validation of an Alpha-Actinin-4 Mutation as a Potential Cause of an Aggressive Presentation of Adolescent Focal Segmental Glomerulosclerosis: Implications for Genetic Testing. PLoS One. 2016; 11(12):e0167467. PMID: 27977723.

Shukha K, Mueller JL, Chung RT, Curry MP, Friedman DJ, Pollak MR, Berg AH. Most ApoL1 Is Secreted by the Liver. J Am Soc Nephrol. 2017 Apr; 28(4):1079-1083. PMID: 27932478.

Pollak M. Genetics of Familial FSGS. Semin Nephrol. 2016 11; 36(6):467-472. PMID: 27987547.

Greka A, Gibson D, Mundel P, Demetri G, Hildebrandt F, Pollak M, Florez J. Personalized Comments on Challenges and Opportunities in Kidney Disease Therapeutics: The Glom-NExT Symposium. Semin Nephrol. 2016 11; 36(6):448. PMID: 27987543.

Bondzie PA, Chen HA, Cao MZ, Tomolonis JA, He F, Pollak MR, Henderson JM. Non-muscle myosin-IIA is critical for podocyte f-actin organization, contractility, and attenuation of cell motility. Cytoskeleton (Hoboken). 2016 Aug; 73(8):377-95. PMID: 27232264.

Subramanian B, Sun H, Yan P, Charoonratana VT, Higgs HN, Wang F, Lai KV, Valenzuela DM, Brown EJ, Schlöndorff JS, Pollak MR. Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury. Kidney Int. 2016 08; 90(2):363-372. PMID: 27350175.

Sharma AK, Friedman DJ, Pollak MR, Alper SL. Structural characterization of the C-terminal coiled-coil domains of wild-type and kidney disease-associated mutants of apolipoprotein L1. FEBS J. 2016 05; 283(10):1846-62. PMID: 26945671; PMCID: PMC4879057.

Friedman DJ, Pollak MR. Apolipoprotein L1 and Kidney Disease in African Americans. Trends Endocrinol Metab. 2016 Apr; 27(4):204-215. PMID: 26947522.

Olabisi O, Al-Romaih K, Henderson J, Tomar R, Drummond I, MacRae C, Pollak M. From man to fish: What can Zebrafish tell us about ApoL1 nephropathy? Clin Nephrol. 2016 Supplement 1; 86 (2016)(13):114-118. PMID: 27509583.

Olabisi OA, Zhang JY, VerPlank L, Zahler N, DiBartolo S, Heneghan JF, Schlöndorff JS, Suh JH, Yan P, Alper SL, Friedman DJ, Pollak MR. APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases. Proc Natl Acad Sci U S A. 2016 Jan 26; 113(4):830-7. PMID: 26699492; PMCID: PMC4743809.

Mukamal KJ, Tremaglio J, Friedman DJ, Ix JH, Kuller LH, Tracy RP, Pollak MR. APOL1 Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults. Arterioscler Thromb Vasc Biol. 2016 Feb; 36(2):398-403. PMID: 26634651.

Allen DB, Backeljauw P, Bidlingmaier M, Biller BM, Boguszewski M, Burman P, Butler G, Chihara K, Christiansen J, Cianfarani S, Clayton P, Clemmons D, Cohen P, Darendeliler F, Deal C, Dunger D, Erfurth EM, Fuqua JS, Grimberg A, Haymond M, Higham C, Ho K, Hoffman AR, Hokken-Koelega A, Johannsson G, Juul A, Kopchick J, Lee P, Pollak M, Radovick S, Robison L, Rosenfeld R, Ross RJ, Savendahl L, Saenger P, Toft Sorensen H, Stochholm K, Strasburger C, Swerdlow A, Thorner M. GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults. Eur J Endocrinol. 2016 Feb; 174(2):P1-9. PMID: 26563978; PMCID: PMC4674592.

2015

MacRae CA, Pollak MR. Effect Size Does Matter: The Long Road to Mechanistic Insight From Genome-Wide Association. Circulation. 2015 Nov 24; 132(21):1943-5. PMID: 26487758.

Feng D, DuMontier C, Pollak MR. The role of alpha-actinin-4 in human kidney disease. Cell Biosci. 2015; 5:44. PMID: 26301083; PMCID: PMC4545552.

Toka HR, Pollak MR, Houillier P. Calcium Sensing in the Renal Tubule. Physiology (Bethesda). 2015 Jul; 30(4):317-26. PMID: 26136545.

Heneghan JF, Vandorpe DH, Shmukler BE, Giovinazzo JA, Giovinnazo JA, Raper J, Friedman DJ, Pollak MR, Alper SL. BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins. Am J Physiol Cell Physiol. 2015 Sep 01; 309(5):C332-47. PMID: 26108665; PMCID: PMC4556898.

Pollak MR. Modifiers of Cardiac Phenotypes. Circ Cardiovasc Genet. 2015 Jun; 8(3):425-6. PMID: 26082553.

Sampson MG, Pollak MR. Opportunities and Challenges of Genotyping Patients With Nephrotic Syndrome in the Genomic Era. Semin Nephrol. 2015 May; 35(3):212-21. PMID: 26215859; PMCID: PMC4745990.

Ruchi R, Genovese G, Lee J, Charoonratana VT, Bernhardy AJ, Alper SL, Kopp JB, Thadhani R, Friedman DJ, Pollak MR. Copy Number Variation at the APOL1 Locus. PLoS One. 2015; 10(5):e0125410. PMID: 25933006; PMCID: PMC4416782.

Ehrlicher AJ, Krishnan R, Guo M, Bidan CM, Weitz DA, Pollak MR. Alpha-actinin binding kinetics modulate cellular dynamics and force generation. Proc Natl Acad Sci U S A. 2015 May 26; 112(21):6619-24. PMID: 25918384; PMCID: PMC4450414.

Pollak MR. Idiopathic pediatric chronic kidney disease: can genomic technology crack the case? J Clin Invest. 2015 May; 125(5):1799-800. PMID: 25893596; PMCID: PMC4463218.

Kopp JB, Winkler CA, Zhao X, Radeva MK, Gassman JJ, D'Agati VD, Nast CC, Wei C, Reiser J, Guay-Woodford LM, Pollak MR, Hildebrandt F, Moxey-Mims M, Gipson DS, Trachtman H, Friedman AL, Kaskel FJ. Clinical Features and Histology of Apolipoprotein L1-Associated Nephropathy in the FSGS Clinical Trial. J Am Soc Nephrol. 2015 Jun; 26(6):1443-8. PMID: 25573908; PMCID: PMC4446865.

2014

Ma L, Shelness GS, Snipes JA, Murea M, Antinozzi PA, Cheng D, Saleem MA, Satchell SC, Banas B, Mathieson PW, Kretzler M, Hemal AK, Rudel LL, Petrovic S, Weckerle A, Pollak MR, Ross MD, Parks JS, Freedman BI. Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines. J Am Soc Nephrol. 2015 Feb; 26(2):339-48. PMID: 25012173; PMCID: PMC4310650.

Rotimi C, Abayomi A, Abimiku A, Adabayeri VM, Adebamowo C, Adebiyi E, Ademola AD, Adeyemo A, Adu D, Affolabi D, Agongo G, Ajayi S, Akarolo-Anthony S, Akinyemi R, Akpalu A, Alberts M, Alonso Betancourt O, Alzohairy AM, Ameni G, Amodu O, Anabwani G, Andersen K, Arogundade F, Arulogun O, Asogun D, Bakare R, Balde N, Baniecki ML, Beiswanger C, Benkahla A, Bethke L, Boehnke M, Boima V, Brandful J, Brooks AI, Brosius FC, Brown C, Bucheton B, Burke DT, Burnett BG, Carrington-Lawrence S, Carstens N, Chisi J, Christoffels A, Cooper R, Cordell H, Crowther N, Croxton T, de Vries J, Derr L, Donkor P, Doumbia S, Duncanson A, Ekem I, El Sayed A, Engel ME, Enyaru JC, Everett D, Fadlelmola FM, Fakunle E, Fischbeck KH, Fischer A, Folarin O, Gamieldien J, Garry RF, Gaseitsiwe S, Gbadegesin R, Ghansah A, Giovanni M, Goesbeck P, Gomez-Olive FX, Grant DS, Grewal R, Guyer M, Hanchard NA, Happi CT, Hazelhurst S, Hennig BJ, Hertz- C, Hide W, Hilderbrandt F, Hugo-Hamman C, Ibrahim ME, James R, Jaufeerally-Fakim Y, Jenkins C, Jentsch U, Jiang PP, Joloba M, Jongeneel V, Joubert F, Kader M, Kahn K, Kaleebu P, Kapiga SH, Kassim SK, Kasvosve I, Kayondo J, Keavney B, Kekitiinwa A, Khan SH, Kimmel P, King MC, Kleta R, Koffi M, Kopp J, Kretzler M, Kumuthini J, Kyobe S, Kyobutungi C, Lackland DT, Lacourciere KA, Landouré G, Lawlor R, Lehner T, Lesosky M, Levitt N, Littler K, Lombard Z, Loring JF, Lyantagaye S, Macleod A, Madden EB, Mahomva CR, Makani J, Mamven M, Marape M, Mardon G, Marshall P, Martin DP, Masiga D, Mason R, Mate-Kole M, Matovu E, Mayige M, Mayosi BM, Mbanya JC, McCurdy SA, McCarthy MI, McIlleron H, Mc'Ligeyo SO, Merle C, Mocumbi AO, Mondo C, Moran JV, Motala A, Moxey-Mims M, Mpoloka WS, Msefula CL, Mthiyane T, Mulder N, Mulugeta Gh, Mumba D, Musuku J, Nagdee M, Nash O, Ndiaye D, Nguyen AQ, Nicol M, Nkomazana O, Norris S, Nsangi B, Nyarko A, Nyirenda M, Obe E, Obiakor R, Oduro A, Ofori-Acquah SF, Ogah O, Ogendo S, Ohene-Frempong K, Ojo A, Olanrewaju T, Oli J, Osafo C, Ouwe Missi Oukem-Boyer O, Ovbiagele B, Owen A, Owolabi MO, Owolabi L, Owusu-Dabo E, Pare G, Parekh R, Patterton HG, Penno MB, Peterson J, Pieper R, Plange-Rhule J, Pollak M, Puzak J, Ramesar RS, Ramsay M, Rasooly R, Reddy S, Sabeti PC, Sagoe K, Salako T, Samassékou O, Sandhu MS, Sankoh O, Sarfo FS, Sarr M, Shaboodien G, Sidibe I, Simo G, Simuunza M, Smeeth L, Sobngwi E, Soodyall H, Sorgho H, Sow Bah O, Srinivasan S, Stein DJ, Susser ES, Swanepoel C, Tangwa G, Tareila A, Tastan Bishop O, Tayo B, Tiffin N, Tinto H, Tobin E, Tollman SM, Traoré M, Treadwell MJ, Troyer J, Tsimako-Johnstone M, Tukei V, Ulasi I, Ulenga N, van Rooyen B, Wachinou AP, Waddy SP, Wade A, Wayengera M, Whitworth J, Wideroff L, Winkler CA, Winnicki S, Wonkam A, Yewondwos M, sen T, Yozwiak N, Zar H. Research capacity. Enabling the genomic revolution in Africa. Science. 2014 Jun 20; 344(6190):1346-8. PMID: 24948725.

Grgic I, Hofmeister AF, Genovese G, Bernhardy AJ, Sun H, Maarouf OH, Bijol V, Pollak MR, Humphreys BD. Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo. Kidney Int. 2014 Dec; 86(6):1116-29. PMID: 24940801.

Pollak MR, Quaggin SE, Hoenig MP, Dworkin LD. The glomerulus: the sphere of influence. Clin J Am Soc Nephrol. 2014 Aug 07; 9(8):1461-9. PMID: 24875196; PMCID: PMC4123398.

Thomson R, Genovese G, Canon C, Kovacsics D, Higgins MK, Carrington M, Winkler CA, Kopp J, Rotimi C, Adeyemo A, Doumatey A, Ayodo G, Alper SL, Pollak MR, Friedman DJ, Raper J. Evolution of the primate trypanolytic factor APOL1. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):E2130-9. PMID: 24808134.

Gbadegesin RA, Hall G, Adeyemo A, Hanke N, Tossidou I, Burchette J, Wu G, Homstad A, Sparks MA, Gomez J, Jiang R, Alonso A, Lavin P, Conlon P, Korstanje R, Stander MC, Shamsan G, Barua M, Spurney R, Singhal PC, Kopp JB, Haller H, Howell D, Pollak MR, Shaw AS, Schiffer M, Winn MP. Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS. J Am Soc Nephrol. 2014 Sep; 25(9):1991-2002. PMID: 24676636.

Barua M, Stellacci E, Stella L, Weins A, Genovese G, Muto V, Caputo V, Toka HR, Charoonratana VT, Tartaglia M, Pollak MR. Mutations in PAX2 associate with adult-onset FSGS. J Am Soc Nephrol. 2014 Sep; 25(9):1942-53. PMID: 24676634; PMCID: PMC4147972.

Brown EJ, Pollak MR, Barua M. Genetic testing for nephrotic syndrome and FSGS in the era of next-generation sequencing. Kidney Int. 2014 May; 85(5):1030-8. PMID: 24599252; PMCID: PMC4118212.

Ito K, Bick AG, Flannick J, Friedman DJ, Genovese G, Parfenov MG, Depalma SR, Gupta N, Gabriel SB, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, Hirschhorn JN, Altshuler DM, Pollak MR, Wilson JG, Seidman JG, Seidman C. Increased burden of cardiovascular disease in carriers of APOL1 genetic variants. Circ Res. 2014 Feb 28; 114(5):845-50. PMID: 24379297; PMCID: PMC3982584.

2013

Genovese G., Friedman D.J., Pollak M.R., APOL1 variants and kidney disease in people of recent African ancestry, Nature Reviews Nephrology, 2013 Feb;online.

Genovese G., Handsaker R.E., Li H., Altemose N., Lindgren A.M., Chambert K., Pasaniuc B., Price A.L., Reich D., Morton C.C., Pollak M.R., Wilson J.G., McCarroll S.A., Using population admixture to help complete maps of the human genome, Nat Genet, 2013 Feb;online.

Kirby A., Gnirke A., Jaffe D.B., Barešová V., Pochet N., Blumenstiel B., Ye C., Aird D., Stevens C., Robinson J.T., Cabili M.N., Gat-Viks I., Kelliher E., Daza R., DeFelice M., Hůlková H., Sovová J., Vylet'al P., Antignac C., Guttman M., Handsaker R.E., Perrin D., Steelman S., Sigurdsson S., Scheinman S.J., Sougnez C., Cibulskis K., Parkin M., Green T., Rossin E., Zody M.C., Xavier R.J., Pollak M.R., Alper S.L., Lindblad-Toh K., Gabriel S., Hart P.S., Regev A., Nusbaum C., Kmoch S., Bleyer A.J., Lander E.S., Daly M.J., Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing, Nature Genetics, 2013 Feb;online.

Quinn S.J., Thomsen A.R., Egbuna O.I., Pang J., Baxi K., Goltzman D., Pollak M.R., Brown E.M., CaSR-mediated Interactions Between Calcium and Magnesium Homeostasis in Mice, Am J Physiol Endocrinol Metab , 2013 Jan;online.

Yao N.Y., Broedersz C.P., Depken M., Becker D.J., Pollak M.R., Mackintosh F.C., Weitz D.A.., Stress-enhanced gelation: a dynamic nonlinearity of elasticity, Phys Rev Lett, 2013 Jan;online.

2012

Carrasquillo R., Tian D., Krishna S., Pollak M.R., Greka A., Schlöndorff J., SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity, BMC Cell Biol, 2012 Nov 21;13:33.

Barua M., Brown E.J., Charoonratana V.T., Genovese G., Sun H., Pollak M.R., Mutations in the INF2 gene account for a significant proportion of familial but not sporadic focal and segmental glomerulosclerosis, Kidney Int, 2012 Feb;83(2):316-22.

Toka H.R., Al-Romaih K., Koshy J.M., DiBartolo S. 3rd, Kos C.H., Quinn S.J., Curhan G.C., Mount D.B., Brown E.M., Pollak M.R., Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria, J Am Soc Nephrol, 2012 Nov;23(11):1879-90.

Lee B.T., Kumar V., Williams T.A., Abdi R., Bernhardy A., Dyer C., Conte S., Genovese G., Ross M.D., Friedman D.J., Gastonb R., Milforda E., Pollak M.R., Chandraker A., The APOL1 Genotype of African American Kidney Transplant Recipients Does Not Impact 5-Year Allograft Survival, Am J Transplant, 2012 Jul;12(7):1924-8.

Xue Y., Xiao Y., Liu J., Karaplis A.C., Pollak M.R., Brown E.M., Miao D., Goltzman D., The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice, Am J Physiol Endocrinol Metab, 2012 Apr 1;302(7):E841-51.

Pollak M.R., Genovese G., Friedman D.J., APOL1 and kidney disease, Curr Opin Nephrol Hypertens, 2012 Mar;21(2):179-82.

Boucher I., Yu W., Beaudry S., Negoro H., Tran M., Pollak M.R., Henderson J.M., Denker B.M., Gα12 activation in podocytes leads to cumulative changes in glomerular collagen expression, proteinuria and glomerulosclerosis, Lab Invest, 2012 May;92(5):662-75.

2011

Kopp J.B., Nelson G.W., Sampath K., Johnson R.C., Genovese G., An P., Friedman D., Briggs W., Dart R., Korbet S., Mokrzycki M.H., Kimmel P.L., Limou S., Ahuja T.S., Berns J.S., Fryc J., Simon E.E., Smith M.C., Trachtman H., Michel D.M., Schelling J.R., Vlahov D., Pollak M., Winkler C.A., APOL1 Genetic Variants in Focal Segmental Glomerulosclerosis and HIV-Associated Nephropathy, Journal of the American Society of Nephrology, 2011 Oct;22:2129-2137.

Friedman D.J., Kozlitina J., Genovese G., Jog P., Pollak M.R., Population-based Risk Assessment of APOL1 on Renal Disease, Journal of the American Society of Nephrology, 2011 Oct;22:2098-2105.

Kanji Z., Powe C.E., Wenger J.B., Huang C., Ankers E., Sullivan D.A., Collerone G., Powe N.R., Tonelli M., Bhan I., Bernhardy A.J., DiBartolo S., Friedman D., Genovese G., Pollak M.R., Thadhani R., Genetic Variation in APOL1 Associates with Younger Age at Hemodialysis Initiation, Journal of the American Society of Nephrology, 2011 Oct;22:2091-2097.

Yao N.I., Becker D., Broedersz C.P., Depken M., MacKintosh F.C., Pollak M.R., Weitz D.A., Nonlinear Viscoelasticity of Actin Transiently 2 Cross-Linked with Mutant α-Actinin-4 Journal of Molecular Biology, Journal of Molecular Biology, 2011 Sep;411(5):1062-1071.

Friedman D.J., Pollak M.R., Genetics of kidney failure and the evolving story of APOL1, J Clin Invest, 2011 Sep;121(9):3367-74.

Al-Romaih K.I., Genovese G., Al-Mojalli H., Al-Othman S., Al-Manea H., Al-Suleiman M., Al-Jondubi M., Atallah N., Al-Rodhyan M., Weins A., Pollak M.R., Adra C.N., Genetic Diagnosis in Consanguineous Families With Kidney Disease by Homozygosity Mapping Coupled With Whole-Exome Sequencing, American Journal of Kidney Diseases, 2011 Aug;58(2):186-195.

Shu L, Ji J, Zhu Q, Cao G, Karaplis A, Pollak MR, Brown E, Goltzman D, Miao D., The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates, J Bone Miner Res, 2011 May;26(5):1057-71.

Sun H., Schlöndorff J.S., Brown E.J., Higgs H.N., Pollak M.R., Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2), Proceedings of the National Academy of Sciences, 2011 Feb;108(7):2933-2938.

Shankland S.J., Pollak M.R., A suPAR circulating factor causes kidney disease, Nat Med, 2011 Aug 4;17(8):926-7.

2010

Broedersz C.P., Depken M., Yao N.Y., Pollak M.R., Weitz D.A., MacKintosh F.C., Cross-link-governed dynamics of biopolymer networks, Phys Rev Lett, 2010 Dec 3;105(23):238101.

Wyss H.M., Henderson J.M., Byfield F.J., Bruggeman L.A., Ding Y., Huang C., Suh J.H., Franke T., Mele E., Pollak M.R., Miner J.H., Janmey P.A., Weitz D.A., Miller R.T., Biophysical properties of normal and diseased renal glomeruli, Am J Physiol Cell Physiol, 2011 Mar;300(3):C397-405.

Freedman B.I., Kopp J.B., Langefeld C.D., Genovese G., Friedman D.J., Nelson G.W., Winkler C.A., Bowden D.W., Pollak M.R., The Apolipoprotein L1 (APOL1) Gene and Nondiabetic Nephropathy in African Americans, Journal of the American Society of Nephrology, 2010 Sep;21(9):1422-1426.

Genovese G., Friedman D.J., Ross M.D., Lecordier L., Uzureau P., Freedman B.I., Bowden D.W., Langefeld C.D., Oleksyk T.K., Uscinski Knob A.L., Bernhardy A.J., Hicks P.J., Nelson G.W., Vanhollebeke B., Winkler C.A., Kopp J.B., Pays E., Pollak M.R., Association of Trypanolytic ApoL1 Variants with Kidney Disease in African-Americans, Science, 2010 Aug;329(5993):841-845.

Genovese G., Tonna S.J., Knob A.U., Appel G.B., Katz A., Bernhardy A.J., Needham A.W., Lazarus R., Pollak M.R., A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9, Kidney International, 2010 Oct;78(7):698-704.

Genovese G., Leibon G., Pollak M.R., Rockmore D.N., Improved IBD detection using incomplete haplotype information, BMC Genetics, 2010 Jun;11:58.

Sun W., Sun W., Liu J., Zhou X., Xiao Y., Karaplis A., Pollak M.R., Brown E., Goltzman D., Miao D., Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice, Development, 2010 Mar;137(6):985-992.

Brown E.J., Schlöndorff J.S., Becker D.J., Tsukaguchi H., Tonna S.J., Uscinski A.L., Higgs H.N., Henderson J.M., Pollak M.R., Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis, Nature Genetics, 2010 Jan;42(1):72-76.

2009

Egbuna O.I., Quinn S.J., Kantham L., Butters R., Pang J.L., Pollak M.R., Goltzman D., Brown E.M., The Full Length Calcium-Sensing Receptor Dampens the Calcemic Response to 1a25(OH)2 Vitamin D3 In vivo Independent of Parathyroid Hormone, American Journal of Physiology-Renal Physiologyl, 2009 May;297(3):F720-F728.

Henderson J.M., Alexander M.P., Pollak M.R., Patients with ACTN4 Mutations Demonstrate Distinctive Features of Glomerular Injury, Journal of the American Society of Nephrology, 2009 May;20(5):961-968.

Schlöndorff J., Del Camino D., Carrasquillo R., Lacey V., Pollak M.R., TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription, American Journal of Physiology-Cell Physiology, 2009 Mar;296(3):C558-C569.

2008

Tonna S.J., Needham A., Polu K., Uscinski A., Appel G.B., Falk R.J., Katz A., Al-Waheeb S., Kaplan B.S., Jerums G., Savige J., Harmon J., Zhang K., Curhan G.C., Pollak M.R., NPHS2 variation in focal and segmental glomerulosclerosis, BMC Nephrology, 2008 Sep;9:13.

Volkmer Ward S.M., Weins A., Pollak M.R., Weitz D.A., Dynamic viscoelasticity of actin cross-linked with wild-type and disease-causing mutant alpha-actinin-4, Biophysical Journal, 2008 Nov;;95(10):4915-4923.

Forman J.P., Fisher N.D., Pollak M.R., Cox D.G., Tonna S.J., Curhan G.C., Renin-Angiotensin System Polymorphisms and Risk of Hypertension: Influence of Environmental Factors, Journal of Clinical Hypertension, 2008 Jun;10(6):459-466.

Tong Z., Yang Z., Patel S., Chen H., Gibbs D., Yang X., Hau V.S., Kaminoh Y., Harmon J., Pearson E., Buehler J., Chen Y., Yu B., Tinkham N.H., Zabriskie N.A., Zeng J., Luo L., Sun J.K., Prakash M., Hamam R.N., Tonna S.J, Constantine R., Ronquillo C.C., Sadda S., Avery R.L., Brand J.M., London N., Anduze A.L., King G.L., Bernstein P.S., Watkins S., Genetics of Diabetes and Diabetic Complication Study Group, Jorde L.B., Li D.Y., Aiello L.P., Pollak M.R., Zhang K., Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications, Proceedings of the National Academy of Sciences, 2008 May;105(19):6998-7003.

Leibon G., Rockmore D.N., Pollak M.R., A SNP streak model for the identification of genetic regions identical-by-descent, Statistical Applications in Genetics and Molecular Biology, 2008 7(1):16.

Tonna S.J., Dandapani S.V., Uscinski A., Appel G.A., Schlöndorff J.S., Zhang K., Denker B.M., Pollak M.R., Functional genetic variation in aminopeptidase A (ENPEP): lack of clear association with focal and segmental glomerulosclerosis (FSGS), Gene, 2008 Feb;410(1):44-52.

Lee S.H., Weins A., Hayes D.B., Pollak M.R., Dominguez R., Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis, Journal of Molecular Biology, 2008 Feb;376(2):317-324.

Henderson J.H., al-Waheeb S., Weins A., Dandapani S.V., Pollak M.R., Mice with altered expression of alpha-actinin-4 exhibit distinct morphologic patterns of glomerular disease, Kidney International, 2008 Mar;73(6):741-750.

2007

Mistry K., Ireland J.H., Ng R.C., Henderson J.M., Pollak M.R., Novel mutations in NPHP4 in a consanguineous family with histological findings of focal segmental glomerulosclerosis, American Journal of Kidney Diseases, 2007 Nov;50(5):855-864.

Weins A., Schlöndorff J.S., Nakamura F., Denker B.M., Hartwig J.H., Stossel T.P., Pollak M.R., A disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin binding affinity, Proceedings of the National Academy of Sciences, 2007 104(41):16080-16085.

Copelovitch L., Guttenberg M., Pollak M.R., Kaplan B.S., Renin-angiotensin axis blockade reduces proteinuria in presymptomatic patients with familial FSGS, Pediatric Nephrology, 2007 22(10):1779-1784.

Dandapani S.V., Sugimoto H., Matthews B.D., Kolb R.J., Sinha S., Gerszten R.E., Zhou J., Ingber D.E., Kalluri R., Pollak M.R., alpha-Actinin-4 is required for normal podocyte adhesion, Jorunal of Biological Chemistry, 2007 282(1):467-477.

2006

Chattopadhyay N., Jeong K.H., Yano S., Huang S., Pang J.L., Ren X., Terwilliger E., Kaiser U.B., Vassilev P.M., Pollak M.R., Brown E.M., Calcium receptor stimulates chemotaxis and secretion of MCP-1 in GnRH neurons in vitro: Potential impact on reduced GnRH neuron population in CaR-null mice, American Journal of Physiology-Endocrinology And Metabolism, 2006 Sep;292(2):3756-3767.

Adams G.B., Chabner K.T., Alley I.R., Olson D.P., Szczepiorkowski Z.M., Poznansky M.C., Kos C.H., Pollak M.R., Brown E.M., Scadden D.T., Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor, Nature, 2006 Feb;439(7076):599-603.

2005

Weins A., Kenlan P., Herbert S, Le T.C., Villegas I., Kaplan B., Appel G., Pollak M.R., Mutational and Biological Analysis of ACTN4 in Focal Segmental Glomerulosclerosis, Journal of the American Society of Nephrology, 2005 16(12):3694-3701.

Reiser J., Polu K.R., Moller C.C., Kenlan P., Altintas M.M., Wei C., Faul C., Herbert S., Villegas I., Avila-Casado C., McGee M., Sugimoto H., Brown D., Kalluri R., Mundel P., Smith P.L., Clapham D.E., Pollak M.R., TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function, Nature Genetics, 2005 May;37(7):739-744.

Hunt J.L., Pollak M.R., Denker B.M., Cultured Podocytes Establish a Size-Selective Barrier Regulated by Specific Signaling Pathways and Demonstrate Synchronized Barrier Assembly in a Calcium Switch Model of Junction Formation, Journal of the American Society of Nephrology, 2005 Mar;16(6):1593-1602.

Leykin I., Hao K., Cheng J., Meyer N., Pollak M.R., Smith R.J., Wong W.H., Rosenow C., Li C., Comparative linkage analysis and visualization of high-density oligonucleotide SNP array data, BMC Genetics, 2005 Feb;6(1):7.

2004

Ellinor P.T., Moore R.K., Patton K.K., Ruskin J.N., Pollak M.R., MacRae C.A., Mutations in the long QT Gene KCNQ1 are an uncommon cause of atrial fibrillation, Heart, 2004 Feb;90(12):1487-1488.

Yao J., Le T.C., Kos C.H., Henderson J.M., Allen P.G., Denker B.M., Pollak M.R., alpha-actinin-4 mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein, PLoS Biology, 2004 Jun;2(6):787-94.

Pereira A.C., Pereira A.B., Mota G.F., Cunha R.S., Herkenhoff F.L., Pollak M.R., Mill J.G., Krieger J.E., NPHS2 R229Q functional variant is associated with microalbuminuria in the general population, Kidney International, 2004 Mar;65(3):1026-30.

2003

Kos C.H., Le T.C., Sinha S., Henderson J., Kim S.H., Sugimoto H., Kalluri R., Gerszten R.E., Pollak M.R., Mice deficint in alpha-actinin-4 have severe glomerular disease, Journal of Clinical Investigation, 2003 Jun;111(11):1683-1690.

Kos C.H., Karaplis A., Peng J-B., Hediger M.A., Goltzman D., Mohammad K.S., Guise T.A., Pollak M.R., The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone, Journal of Clinical Investigation, 2003 Jan;111(7):1021-1028.

2002

Pollak M.R., Inherited podocytopathies: FSGS and nephrotic syndrome from a genetic viewpoint, Journal of the American Society of Nephrology, 2002 Dec;13:3016-3023.

Tsukaguchi H., Sudhakar A., Le T.C., Nguyen T., Yao J., Schwimmer J., Schachter A., Poch E., Abreu P.F., Appel G., Pereira A.B., Kalluri R., Pollak M.R., NPHS2 Mutations in Late-onset Focal Segmental Glomerulosclerosis: R229Q is a Common Disease-Associated Allele, Journal of Clinical Investigation, 2002 Dec;110(11):1659-1666.

2001

Kaplan J.M., Pollak M.R., Familial focal segmental glomerulosclerosis, Current Opinion in Nephrology and Hypertension, 2001 Mar;10(2):183-187.

2000

Tsukaguchi H., Yager H., Dawborn J., Jost L., Cohlmia J., Abreu P., Pereira A., Pollak M.R., A locus for adolescent and adult onset focal segmental glomerulosclerosis on chromsome 1q25-31, Journal of the American Society of Nephrology, 2000 Sep;11:1674-1680.

Olszak I.T., Poznansky M.C., Evans R.H., Kos C.H., Pollak M.R., Brown E.M., Scadden D.T., Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo, Journal of Clinical Investigation, 2000 May;105(9):1299-1305.

Kaplan J.M., Kim S.h., North K.N., Rennke H., Correia L.A., Tong H.Q., Mathis B.J., Rodriguez-Perez J.C., Allen P.G., Beggs A.H., Pollak M.R., Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis, Nature Genetics, 2000 Mar;24(3):251-256.

1999

Gherman R.B., Bowen E., Eggleston M.K., Teague K.E., Sayles T., Brown E.M., Pollak M.R., Successful pregnancy outcome in a woman with a gain-of-function mutation of the calcium-sensing receptor. A case report, Journal of Reproductive Medicine, 1999 Aug;44(8):745-747.

1998

Mathis B., Kim S.H., Calabrese K., Haas M., Seidman J.G., Seidman C.E., Pollak M.R., Rapid Communication: A locus for inherited focal segmental glomerulosclerosis maps to chromosome 19q13, Kidney International, 1998 Feb;53:282-286.

1996

Bai M., Quinn S., Trivedi S., Kifor O., Pearce S.H.S., Pollak M.R., Krapcho K., Hebert S.C., Brown E.M., Expression and characterization of inactivating and activating mutations in the human Ca2+o-sensing receptor, Journal of Biological Chemistry, 1996 Aug;271(32):19537-19545.

Karolyi L., Ziegler A., Pollak M.R., Fischbach M., van Acker K.J., Grzeschik K-H., Koch M.C., Seyberth H.W., Gitelman's syndrome is genetically distinct from Bartter's syndrome and hyperprostaglandin E syndrome, Pediatric Nephrology, 1996 Oct;10(5):551-554.

Pollak M.R., Delaney V., Graham R., Hebert S.C., Gitelman's syndrome (Bartter's variant) maps to the thiazide-sensitive cotransporter gene locus on chromosome 16q13 in a large kindred, Journal of the American Society of Nephrology, 1996 Oct;7(10):2244-2248.

1995

Hosokawa Y., Pollak M.R., Moore F., Brown E.M., Arnold A., Mutational analysis of the extracellular Ca2+-sensing receptor gene in human parathyroid tumors, Journal of Clinical Endocrinology and Metabolism, 1995 Nov;80(11):3107-3110.

Ho C., Conner D.A., Pollak M.R., Ladd D.J., Kifor O., Warren H.B., Brown E.M., Seidman J.G., Seidman C.E., A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism, Nature Genetics, 1995 Dec;11(4):389-394.

Chou Y-H.W., Pollak M.R., Brandi M.L., Toss G., Arnqvist H., Atkinson A.B., Papapoulos S.E., Marx S., Brown E.M., Seidman J.G., Seidman C.E., Mutations in the human Ca2+-sensing-receptor gene that cause familial hypocalciuric hypercalcemia, American Journal of Human Genetics, 1995 May;56(5):1075-1079.

1994

Pollak M.R., Brown E.M., Estep H.L., McLaine P.N., Kifor O., Park J., Hebert S.C., Seidman C.E., Seidman J.G., Autosomal dominant hypocalcemia caused by a Ca2+-sensing receptor gene mutation, Nature Genetics, 1994 Nov;8(3):303-307.

Pollak M.R., Chou Y-H.W., Marx S.J., Steinmann B., Cole D.E., Brandi M.L., Papapoulos S.E., Menko F.H., Hendy G.H., Brown E.M., Seidman C.E., Seidman J.G., Familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism: effects of mutant gene dosage on phenotype, Journal of Clinical Investigation, 1994 Mar;93(3):1108-1112.

1993

Pollak M.R., Brown E.M., Chou Y-H.W., Hebert S.C., Marx S.J., Steinmann B., Levi T., Seidman C.E., Seidman J.G., Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism, Cell, 1993 Dec;75(7):1297-1303.

Pollak M.R., Chou Y-H.W., Cerda J.J., Steinmann B., La Du B.N., Seidman J.G., Seidman C.E., Homozygosity mapping of the gene for alkaptonuria to chromosome 3q2, Nature Genetics, 1993 Oct;5(2):201-204.

1988

Blank R.D., Campbell G.R., Pollak M.R., D'Eustachio P., Bayesian multilocus linkage mapping, Current Topics in Microbiology and Immunology, 1988 137:25-32.

1984

Pollak M.R., Schuler R.H., Numerical treatment of the kinetics of track processes in radiation chemistry, Radiation Physics and Chemistry, 1984 23:285-291.