Kwon lab

Microglia, Brain aging, Rejuvenation, Metabolic Reprogramming

Welcome to the Kwon Lab in the Department of Pharmacology at CHA University School of Medicine.

Led by Dr. Min-Soo Kwon, our laboratory focuses on uncovering the complex roles of microglia in brain aging and neurodegenerative diseases. Through advanced pharmacological approaches, we aim to discover novel therapeutic targets for brain disorders via microglial rejuvenation. To translate our groundbreaking bench-side discoveries into clinical realities, we have founded Brainimmunex (www.brainimmunex.com), a faculty-led biotech startup dedicated to developing next-generation therapeutics that restore aged brain immunity.

Kwon Lab of Pharmacology & Microglia | CHA University

Senescent microglia: a universal target in neurodegenerative diseases

Our hypothesis

We hypothesize that metabolic reprogramming, achieved by recycling the lipid droplets accumulated in aged microglia, can drive cellular rejuvenation and, ultimately, brain rejuvenation.

Phagocytosis

Assessment of microglial uptake and clearance functions.

3D Image Analysis

Quantitative visualization and analysis of cellular morphology and interactions using Imaris.

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