◎ 學歷
Department of Biomedical Engineering & Medical Device Innovation Center, National Cheng Kung University, TAIWAN (2016)
Orthopedic Biomechanics Laboratory, Department of Orthopedic Surgery, Mayo Clinic, Rochester MN, USA (2011-2016)
Ph. D. of Biomedical Engineering, National Cheng Kung University, Taiwan (2008~2015)
M.S. program of Biomedical Engineering, National Cheng Kung University, Taiwan (2007~2008)
M.D. School of Chinese Medicine, China Medical University, Taiwan (1990~1997)
◎ 經歷
Assistant Professor Department of Biomedical Engineering & Medical Device Innovation Center, National Cheng Kung University, TAIWAN, 2016 ~ 2021
Research Fellow, Orthopedic Biomechanics Laboratory, Department of Orthopedic Surgery, Mayo Clinic, Rochester MN, USA, 2011-2016
Attending Physician, Department of Orthopedics, China Medical University Hospital, Taichung, TAIWAN, 2006-2016
Director, Medical Division and Department of Orthopedics, Caotun Branch (草屯分院), China Medical University Hospital, Taichung, TAIWAN, 2007-2009
Director, Medical Division and Department of Orthopedics, Fengyuan Branch (豐原分院), China Medical University Hospital, Taichung, TAIWAN, 2007-2009
Attending Physician, Department of Orthopedics, Medical Treatment Special Quarter, Taichung Prison Administration, TAIWAN, 2006-2007
Tutor, Problem-based learning (PBL) Group, China Medical University, TAIWAN, 2005-2011
Instructor, Clinical Skills Group, China Medical University, TAIWAN, 2005-2011
Executive Secretary, Rating Teacher and Standardized Patient, Objective Structured Clinical Examination (OSCE) Organization, China Medical University, TAIWAN, 2005-2011
PGY/UGY core curriculum teacher, Department of General Surgery, China Medical University Hospital, TAIWAN, 2005-2011
Member, Medical Records Management Committee, China Medical University Hospital, TAIWAN, 2005-2011
Member, Medical Education Committee, China Medical University Hospital, TAIWAN, 2005-2011
Member, Medical Ethics Committee, China Medical University Hospital, TAIWAN, 2005-2011
Clinical Fellow, Department of Orthopedics, China Medical University Hospital, TAIWAN, 2005-2006
Chief Resident, Department of Orthopedics, China Medical University Hospital, TAIWAN, 2004-2005
Resident, Department of Orthopedics, China Medical University Hospital, TAIWAN, 1999-2004
◎ 研究主題與內容
Research Specialties:
Orthopedic Biomechanics
Medical Image
Molecular Biology
Clinical Specialties:
Hand Surgery & Microsurgery
Orthopedic Traumatology
Arthroplasty
學術成大 https://researchoutput.ncku.edu.tw/en/persons/tai-hua-yang
◎ 論文發表及獲獎
Selected Peer-Reviewed Publications
1. Yang TH, Lin YH, Chuang BI, Chen HC, Lin WJ, Yang DS, Wang SH, Sun YN, Jou IM, Kuo LC, Su FC. Identification of the Position and Thickness of the First Annular Pulley in Sonographic Images. Ultrasound Med Biol. 2016 Jan 28. pii: S0301-5629(15)00731-0. doi: 10.1016/j.ultrasmedbio.2015.12.007. [Epub ahead of print]
2. Yang TH, Thoreson AR, An KN, Zhao C, Conover CA, Amadio PC. PAPP-A affects tendon structure and mechanical properties. J Struct Biol. 2015 Oct;192(1):59-66. doi: 10.1016/j.jsb.2015.08.012. Epub 2015 Aug 22. PMID: 26306763
3. Wang Z, Perez-Terzic CM, Smith J, Mauck WD, Shelerud RA, Maus TP, Yang TH, Murad MH, Gou S, Terry MJ, Dauffenbach JP, Pingree MJ, Eldrige JS, Mohammed K, Benkhadra K, van Wijnen AJ, Qu W. Efficacy of intervertebral disc regeneration with stem cells - a systematic review and meta-analysis of animal controlled trials. Gene. 2015 Jun 10;564(1):1-8. doi: 10.1016/j.gene.2015.03.022. Epub 2015 Mar 19. Review. PMID: 25796605
4. Rappaport PO, Thoreson AR, Yang TH, Reisdorf RL, Rappaport SM, An KN, Amadio PC. Effect of wrist and interphalangeal thumb movement on zone T2 flexor pollicis longus tendon tension in a human cadaver model. J Hand Ther. 2015 Oct-Dec;28(4):347-54; quiz 355. doi: 10.1016/j.jht.2015.04.002. Epub 2015 Apr 14. PMID: 26209161
5. Lu SC, Yang TH, Kuo LC, Jou IM, Sun YN, Su FC. Effects of different extents of pulley release on tendon excursion efficiency and tendon moment arms. J Orthop Res. 2015 Feb;33(2):224-8. doi: 10.1002/jor.22747. Epub 2014 Oct 8. PMID: 25297915
6. Yang TH, Thoreson AR, Gingery A, Larson DR, Passe SM, An KN, Zhao C, Amadio PC. Collagen gel contraction as a measure of fibroblast function in an animal model of subsynovial connective tissue fibrosis. J Orthop Res. 2015 May;33(5):668-74. doi: 10.1002/jor.22835. Epub 2015 Mar 18. PMID: 25626430
7. Gingery A, Yang TH, Passe SM, An KN, Zhao C, Amadio PC. TGF-β signaling regulates fibrotic expression and activity in carpal tunnel syndrome. J Orthop Res. 2014 Nov;32(11):1444-50. doi: 10.1002/jor.22694. Epub 2014 Jul 30. PMID: 25073432
8. Yang TH, Thoreson AR, Gingery A, An KN, Larson DR, Zhao C, Amadio PC. Collagen gel contraction as a measure of fibroblast function in carpal tunnel syndrome. J Biomed Mater Res A. 2015 Feb;103(2):574-80. doi: 10.1002/jbm.a.35200. Epub 2014 May 7. PMID: 24753289
9. Yang TH, Chen HC, Liu YC, Shih HH, Kuo LC, Cha S, Yang HB, Yang DS, Jou IM, Sun YN, Su FC. Clinical and pathological correlates of severity classifications in trigger fingers based on computer-aided image analysis. Biomed Eng Online. 2014 Jul 23;13:100. doi: 10.1186/1475-925X-13-100. PMID: 25055721
10. Filius A, Thoreson AR, Yang TH, Vanhees M, An KN, Zhao C, Amadio PC. The effect of low- and high-velocity tendon excursion on the mechanical properties of human cadaver subsynovial connective tissue. J Orthop Res. 2014 Jan;32(1):123-8. doi: 10.1002/jor.22489. Epub 2013 Sep 13. PMID: 24038298
11. Liu YC, Chen HC, Shih HH, Yang TH, Yang HB, Yang DS, Su FC, Sun YN. Computer aided quantification of pathological features for flexor tendon pulleys on microscopic images. Comput Math Methods Med. 2013;2013:914124. doi: 10.1155/2013/914124. Epub 2013 Jun 6. PMID: 23840282
12. Chen HC, Yang TH, Thoreson AR, Zhao C, Amadio PC, Sun YN, Su FC, An KN. Automatic and Quantitative Measurement of Collagen Gel Contraction Using Model-Guided Segmentation. Meas Sci Technol. 2013 Aug;24(8):85702. PMID: 24092954
13. Kuo LC, Yang TH, Hsu YY, Wu PT, Lin CL, Hsu HY, Jou IM. Is progressive early digit mobilization intervention beneficial for patients with external fixation of distal radius fracture? A pilot randomized controlled trial. Clin Rehabil. 2013 Nov;27(11):983-93. doi: 10.1177/0269215513487391. Epub 2013 Jun 20. PMID: 23787939
14. Liu YC, Shih HH, Yang TH, Yang HB, Yang DS, Sun YN. Quantitative Measurement for Pathological Change of Pulley Tissue from Microscopic Images via Color-Based Segmentation. (2012) Lecture Notes in Computer Science 2012 (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 7198 LNAI (PART 3) PP. 476 - 485 doi: 10.1007/978-3-642-28493-9_50
15. Lai KY, Hsu HM, Yang TH, Jou IM, Lai SY, Kuo LC. Investigation of the Injured Mechanism of the Hand During Piano Playing Based on Ergonomic and Kinematic Perspectives. 以人因觀點及運動學表現探究鋼琴彈奏之手部傷害. JTOTA 2012職能治療協會雜.2012; 30卷第1期頁7-33
16. Chen HC, Chen CK, Yang TH, Kuo LC, Jou IM, Su FC, Sun YN. Model-based segmentation of flexor tendons from magnetic resonance images of finger joints. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:8009-12. doi: 10.1109/IEMBS.2011.6091975. PMID: 22256199
17. Yang TH, Fong YC, Hsu HC, Jim YF, Chiang IP, Lin MJ. Re: ossifying lipoma of the hand. J Hand Surg Eur Vol. 2008 Feb;33(1):82-3. doi: 10.1177/1753193407087863. PMID:18332028
Manuscript at Journal Reviewing
1. Yang TH, Lu SC, Lin WJ, Zhao K, Zhao C, An KN, Jou IM, Kuo LC, Su FC. Assessing Finger Joint Biomechanics by Applying Equal Force to Flexor Tendons in Vitro Using a Novel Closed-System Model (2015) PLOS ONE (manuscript at journal)
2. Yang TH, Gingery A, Thoreson AR, Larson DR, Zhao C, Amadio PC. Triamcinolone Acetonide Affects TGF-β Signaling Regulation of Fibrosis in Idiopathic Carpal Tunnel Syndrome (2016) Journal of Hand Surgery: American Volume (manuscript at journal)
Manuscript in Preparation
1. Chuang BI, Kuo LC, Yang TH, Su FC, Jou IM, Lin WJ, Sun YN. Medical Imaging Analysis System for Trigger Finger Using Adaptive Texture-Based Active Shape Model (ATASM) In Ultrasound Images (2015) Ultrasound in medicine and biology (manuscript in preparation)
2. Yang TH, Riester SM, Gingery A, Zhao C, van Wijnen AJ, Amadio PC. RNA Sequencing Analyzes Transcriptomic Differences Between Intrasynovial and Extrasynovial Areas of The Flexor Digitorum Profundus (2016) The Journal of Bone & Joint Surgery (manuscript in preparation)
Conferences
1. Yang TH, Thoreson AR, Gingery A, Larson DR, Passe SM, An KN, Zhao C, Amadio PC. Cell-Seeded Contraction Gel Model to Assess TGF-β and Fibroblast Biomechanics in an Established Rabbit Model of Carpal Tunnel Syndrome. ORS 2015 Annual Meeting, Las Vegas, NV, USA
2. Gingery A, Yang TH, Passe SM, An KN, Zhao C, Amadio PC. Unique Genetic Signature and Therapeutic Targets for Diabetic Carpal Tunnel Patients. ORS 2015 Annual Meeting, Las Vegas, NV, USA
3. Yang TH, Gingery A, Thoreson AR, An KN, Zhao C, Amadio PC. The Effect of Triamcinolone Acetonide on Idiopathic Carpal Tunnel Syndrome fibroblasts – a Biomechanical Study. 69th annual meeting of the ASSH, Boston, MA, USA, 2014
4. Gingery A, Yang TH, An KN, Zhao C, Amadio PC. Fibrotic Gene Expression in Diabetic Patients with Carpal Tunnel Syndrome. 69th annual meeting of the ASSH, Boston, MA, USA, 2014
5. Yang TH, Gingery A, Thoreson AR, An KN, Zhao C, Amadio PC. Cell-Seeded Contraction Gel Model to Assess Fibroblast Function in Carpal Tunnel Syndrome. ORS 2014 Annual Meeting, New Orleans, LA, USA
6. Gingery A, Yang TH, An KN, Zhao C, Amadio PC. Targeted Blocking of TGF-β Receptor I Signaling in Subsynovial Connective Tissue in Carpal Tunnel Syndrome Reduces Fibrotic Gene Expression. ORS 2014 Annual Meeting, New Orleans, LA, USA
7. Chuang BI, Sun YN, Yang TH, Su FC, Kuo LC, Jou IM. Model-based tendon segmentation from ultrasound images. Bioengineering Conference (NEBEC), 2014 40th Annual Northeast, Pages: 1 - 2, DOI: 10.1109/NEBEC.2014.6972757
8. Chen HC, Yang TH, Chen CK, Chu MT, Jou IM, Su FC, Sun YN. Virtual Hand Modeling for Ultrasound-Guided Percutaneous Surgical Simulator. (2014) 2014 IEEE Healthcare Innovation Conference, HIC Pages: 263 - 266, doi: 10.1109/HIC.2014.7038925
9. Lin YH, Yang TH, Wang SH, Su FC. Effect of Scanning Direction on The Statistical Parameters of Ultrasonic Signals Backscattered from the Annular Pulley and Tendon. 2013 IEEE International Ultrasonics Symposium (IUS), Prague, Pages: 409 - 412, DOI: 10.1109/ULTSYM.2013.0106.
10. Chen HC, Yang TH, Thoreson AR, Zhao C, Amadio PC, Su FC, Jia W, Sun YN, An KN, Sun M. Multiresolution Image Analysis for Automatic Quantification of Collagen Gel Contraction. Bioengineering Conference (NEBEC), PP. 64 – 65; 2013 39th Annual Northeast , Syracuse, NY, USA, 2013 (doi: 10.1109/NEBEC.2013.115)
11. Sun YL, Zhao C, Yang TH, Jay G, Schmid T, Amadio PC, An KN. Sliding Motion and Shear Stress in Human Achilles Tendon. ORS 2013 Annual Meeting, SAT, TX, USA
12. Gingery A, Yang TH, Zhao C, An KN, Amadio PC. Transforming Growth Factor β Signaling and Fibrotic Gene Expression is Upregulated in Carpal Tunnel Syndrome. ORS 2013 Annual Meeting, SAT, TX, USA
13. Yang TH, Lu SC, Lin WJ, Zhao K, Zhao C, Kuo LC, Jou IM, An KN, Su FC. A Novel Model to Assess the Contributions of Flexor Tendons in Finger Joint Motion. ORS 2013 Annual Meeting, SAT, TX, USA
14. Yang TH, Conover CA, Vanhees M, Thoreson AR, Zhao C, An KN, Amadio PC. PAPP-A Affects Tendon Development and Material Properties. ORS 2013 Annual Meeting, SAT, TX, USA
15. Yang TH, Lu SC, Lin WJ, Zhao K, Zhao C, Kuo LC, Jou IM, An KN, Su FC. Preliminary Assessment of Flexor Tendons Contribution in Required Finger Joint Motion: A Novel Research Method. The 8th International Hand and Wrist Biomechanics Symposium, Yokohama, Japan, 2012
16. Yang TH, Lin YH, Lin WJ, Kuo LC, Jou IM, Wang SH, Su FC. High Frequency Sonography Characterizing Individual Tissue in Pulley System. The 8th International Hand and Wrist Biomechanics Symposium, Yokohama, Japan, 2012
17. Yang TH, Liu YC, Shih HH, Yang HB, Yang DS, Kuo LC, Sun YN, Su FC. Quantitative Measurement for Pathological Microscopic Image of A1 Pulley by Digital Image Process. The 8th International Hand and Wrist Biomechanics Symposium, Yokohama, Japan, 2012
18. Liu YC, Shih HH, Yang TH, Yang HB, Yang DS, Sun YN. Quantitative Measurement for Pathological Change of Pulley Tissue from Microscopic Images via Color-Based Segmentation. The 4th Asian Conference on Intelligent Information and Database Systems, Taiwan, 2012
19. Lin YH, Yang TH, Wang SH, Su FC. Characterization of Tissue in the Pulley System Using High-Frequency Ultrasonic Backscatter Signals. IEEE International Ultrasonics Symposium, IUS PP. 1345 - 1348 doi: 10.1109/ULTSYM.2011.0332. Orlando, FL, USA, 2011
20. Chen HC, Chen CK, Yang TH, Kuo LC, Jou IM, Su FC, Sun YN. Model-Based Segmentation of Flexor Tendons from Magnetic Resonance Images of Finger Joints. The 33rd Annual International IEEE EMBS Conference, Boston, USA, 2011
21. Yang TH, Chen ZY, Hsu YY, Kuo LC, Lin MJ, Jou IM. A Novel Concept of a 3D Kinematic Model to Assess Ranges of Wrist Joint Motion: Establishment of Young Adult Model. Annual meeting of Orthopedic Association ROC, Taiwan, 2010
22. Yang TH, Lu SC, Su FC, Kuo LC, Chiu HY, Jou IM, Sun YN. Introduction of Hand Biomechanics Laboratory in NCKU. Annual meeting of Society for Surgery of the hand, Taiwan, 2010
23. Yang TH, Huang PY, Lee IJ, Lee YY, Lin CF, Lin MJ, Hsu HC. The Lower Extremities Biomechanical Analysis in the Diagonal Step of Badminton Players: a Pilot Study. Annual meeting of Orthopedic Association ROC, Taiwan, 2009
24. Hsieh MH, Kuo CC, Yang TH, Hsu CJ, Hsu HC. Fracture of Humeral Shaft Treated With Intramedullary K Wires: Compared With Traditional Method. Annual meeting of Orthopedic Association ROC, Taiwan, 2007
25. Huang PH, Lin WC, Kuo CC, Yang TH, Hsu HC. Revascularization Versus Reconstruction of Degloving Injuries of the Heel. Annual meeting of Orthopedic Association ROC, Taiwan, 2007
26. Yang TH, Fong YC, Hsu HC, Jim YF, Chiang IP, Lin MJ. Ossifying Lipoma of The Hand: Rare Case Report and Literature Review. Annual meeting of Orthopedic Association ROC, Taiwan, 2007
27. Yeh YC, Yang TH, Fong YC, Hsu HC. Glomus Tumor (Glomangioma) of The Elbow: A Rare Case Presentation. Annual meeting of Orthopedic Association ROC, Taiwan, 2006
28. Yang TH, Lin WC, Tu YK, Hsu HC. Traumatic Traction Avulsion Amputation of The Major Limb: a Minimum Follow-Up of One Year. Annual meeting of Orthopedic Association ROC, Taiwan, 2006
29. Yang TH, Lin WC, Hsu HC. Traumatic Traction Avulsion Amputation of The Major Limb: Preliminary Result of 4 cases. Annual meeting of Orthopedic Association ROC, Taiwan, 2004
30. Yang TH, Lin MJ, Hsu HC. Recurrent Dissociation of a Morse-Taper Stemmed Femoral Component Following Modular Custom Made Total Knee Arthroplasty: a Case Report. Annual meeting of Orthopedic Association ROC, Taiwan, 2003
31. Yang TH, Fong YC, Hsu HC, Jim YF, Chiang IP, Lin MJ. Fibroma of Tendon Sheath in The Proximal Forearm With Associated PION Neuropathy: a Case report. Annual meeting of Orthopedic Association ROC, Taiwan, 2002