Mayola Senior established the first Xinos Chapter in Toledo, Ohio. In that city the group was called TOPS instead of Xinos because the high school there prohibited Greek letter organizations. The aims of the group were to inspire girls to achieve high scholastic records, to furnish guidance, and to enhance their cultural backgrounds. Sorority members worked diligently to achieve these aims.

In 1948, after the annual Conclave held in Newark, New Jersey, Julia A. Barnes, a Founder, aided by Alpha Chapter member Esther Cooke, invited ten high school girls to meet at the home of Founder Barnes to form a Xinos group. Thus, the first chapter east of the Mississippi River was established for Alpha Chapter in Jersey City, New Jersey.

The group grew, and they engaged in many worthwhile activities, including tutoring, discussions on careers, philanthropy, and gifts to the needy at Christmas time, trips to cultural events as well as social gatherings chaperoned by their parents and sorority members.

Today, nearly all of the chapters of the National Sorority of Phi Delta Kappa, Inc. have Xinos Chapters. Sorority members work diligently to keep the Xinos alive, by providing an active, viable group so young ladies will aspire to become members. Each of the five regions holds its Xinos Regional Conference annually.