Materials Integrated Nanobio Laboratory (MIN Lab.)
Materials Integrated Nanobio Laboratory (MIN Lab.)
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Research Topics
Research Topics
The research topics of MIN Lab. of Hallym University, Major in Materials Science & Engineering are as follows:
The research topics of MIN Lab. of Hallym University, Major in Materials Science & Engineering are as follows:
1. Autodisplay technology
1. Autodisplay technology
Engineering of affinity proteins and active enzymes for autodisplay
Application of autodisplaying bacteria cells or membrane to immunoassays & biosensors
2. Medical diagnosis
2. Medical diagnosis
Orientation control of antibodies for the sensitive medical diagnosis
Wash-free & non-labeling assays
3. Biosensors
3. Biosensors
Effective molecular recognition layer for the sensitivity improvement
Highly sensitive electrochemical enzyme-based biosensors
Autodisplay Technology
Autodisplay Technology
Expression system for the display of recombinant proteins on the outer membrane of Gram-negative bacteria
Developed for translocation studies, biocatalysis, bioremediation, inhibitor screening including drug discovery, enzyme folding, vaccine development, immunoassays, and biosensors
Display of 100 % oriented target proteins with high density (more than 100,000 molecules per cell)
Can provide a membrane environment sufficient for functional enzyme display
Medical Diagnosis
Medical Diagnosis
Orientation control of antibodies for the improvement of immunoassay by autodisplay of affinity proteins
Medical diagnosis of real samples (human serum, urine, peritoneal dialysate, and other physiological fluids)
Biosensors
Biosensors
Immunoaffinity layer based on the autodisplay of affinity proteins
Enzymatic electochemical biosensors
Fluidic biosensors for the real-time monitoring
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