Publications
Selected Publications:
Xingzhi He1, Yang Wang1, Guangjun Zhou, Jing Yang, Jiarui Li, Tao Li, Hailan Hu, Huan Ma. A Critical Role for gCaMKII in Decoding NMDA Signaling to Regulate AMPA Receptors in Putative Inhibitory Interneurons. Neurosci Bull. 2022.
Kwan Tung Li1, Xingzhi He1, Guangjun Zhou, Jing Yang, Tao Li, Hailan Hu, Daoyun Ji, Changsong Zhou*, Huan Ma*. Rational designing of oscillatory rhythmicity for memory rescue in plasticity-impaired learning networks. Cell Reports. 2022.
Yue Pan1 , Guangjun Zhou1, Wenwen Li1, Xingzhi He, Cuicui Li, Yanjun Li, Tao Li, Hailan Hu, Huan Ma*. Excitation-transcription coupling via synapto-nuclear signaling triggers autophagy for synaptic turnover and long-lasting synaptic depression. Autophagy, 30 August, 2021.
Yue Pan1, Xingzhi He1, Cuicui Li1, Yanjun Li1, Wenwen Li, Hanbin Zhang, Yang Wang, Guangjun Zhou, Jing Yang, Jiarui Li, Jing Qu, Hao Wang, Zhihua Gao, Ying Shen, Tao Li, Hailan Hu, Huan Ma*.Neuronal activity recruits the CRTC1/CREB axis to drive transcription-dependent autophagy for maintaining late-phase LTD. Cell Reports, 20 July, 2021.
Xingzhi He1, Jiarui Li1, Guangjun Zhou1, Jing Yang1, Sam McKenzie, Yanjun Li, Wenwen Li, Jun Yu, Yang Wang, Jing Qu, Zhiying Wu, Hailan Hu, Shumin Duan, Huan Ma*. Gating of hippocampal rhythms and memory by synaptic plasticity in inhibitory interneurons.Neuron, 5 Feb 2021
Samuel M. Cohen1, Benjamin Suutari1, Xingzhi He1, Yang Wang, Sandrine Sanchez, Natasha N. Tirko, Nataniel J. Mandelberg, Caitlin Mullins, Guangjun Zhou, Shuqi Wang, Ilona Kats, Alejandro Salah, Richard W. Tsien*, Huan Ma*. Calmodulin shuttling mediates cytonuclear signaling to trigger experience-dependent transcription and memory. Nature Communications. 9(1):2451 Jun 2018
Huan Ma*, Rachel D. Groth, Samuel Cohen, John Emery, Boxing Li, Esthelle Hoedt, Guoan Zhang, Thomas A. Neubert, Richard W. Tsien*. gCaMKII shuttles CaM to the nucleus to trigger CREB phosphorylation and gene expression. Cell, Volume 159, Issue 2, 9 Oct 2014, Pages 281–294
Damian G. Wheeler1, Rachel D. Groth1, Huan Ma1*, Curtis F. Barrett, Scott F. Owen, Parsa Safa, Richard W. Tsien*. Specific calcium channel types engage different modes of Ca2+ signaling to control CREB phosphorylation and gene expression.Cell, Volume 149, Issue 5, 25 May 2012, Pages 1112–1124
Samuel Cohen, Boxing Li, Richard W. Tsien, Huan Ma*. Evolutionary and Functional Perspectives on Signaling from Neuronal Surface to Nucleus. Biochemical and Biophysical Research Communications, Volume 460, Issue 1, 24 April 2015, Pages 88–99
Samuel Cohen, Huan Ma, Kishore Kuchibhotla, Robert C. Froemke, Richard W. Tsien. Excitation-transcription coupling in parvalbumin+ interneurons employs a CaM Kinase-dependent pathway different from that in pyramidal neurons. Neuron 90, 292–307, April 20, 2016
Huan Ma, Qian Cai, Wen-Bo Lu, Zu-Hang Sheng, Sumiko Mochida. KIF5B Motor Adaptor Syntabulin Maintains Synaptic Transmission in Sympathetic Neurons. The Journal of Neuroscience, October 14, 2009, 29(41):13019-13029
Publications:
Samuel Cohen, Huan Ma, Kishore Kuchibhotla, Robert C. Froemke, Richard W. Tsien. Excitation-transcription coupling in parvalbumin+ interneurons employs a CaM Kinase-dependent pathway different from that in pyramidal neurons. Neuron 90, 292–307, April 20, 2016
Samuel Cohen, Boxing Li, Richard W. Tsien, Huan Ma*. Evolutionary and Functional Perspectives on Signaling from Neuronal Surface to Nucleus. Biochemical and Biophysical Research Communications, Volume 460, Issue 1, 24 April 2015, Pages 88–99
Huan Ma*, Boxing Li, Richard Tsien*. Distinct roles of multiple isoforms of CaMKII in signaling to the nucleus. Biochim Biophys Acta (BBA) - Molecular Cell Research, 2015, Feb 17
Michikata Hayashida, Shota Tanifuji, Huan Ma, Noriko Murakami, Sumiko Mochida. Neural activity selects myosin IIB and VI with specific time window in distinct dynamin isoforms-mediated synaptic vesicle reuse pathways. The Journal of Neuroscience, 10 June 2015, 35(23): 8901-8913
Huan Ma*, Rachel D. Groth, Samuel Cohen, John Emery, Boxing Li, Esthelle Hoedt, Guoan Zhang, Thomas A. Neubert, Richard W. Tsien*. gCaMKII shuttles CaM to the nucleus to trigger CREB phosphorylation and gene expression. Cell, Volume 159, Issue 2, 9 Oct 2014, Pages 281–294
Damian G. Wheeler1, Rachel D. Groth1, Huan Ma1*, Curtis F. Barrett, Scott F. Owen, Parsa Safa, Richard W. Tsien*. Specific calcium channel types engage different modes of Ca2+ signaling to control CREB phosphorylation and gene expression.Cell, Volume 149, Issue 5, 25 May 2012, Pages 1112–1124
Huan Ma*, Samuel Cohen, Boxing Li, Richard W. Tsien*. Exploring the dominant role of Cav1 channels in signaling to the nucleus. Biosci Rep. 2012 Oct 23:97-101.
Huan Ma, Rachel D. Groth, Damian G. Wheeler, Curtis F. Barrett, Richard W. Tsien. Excitation-transcription coupling in SCG neurons and the molecular mechanism of its initiation. Neuroscience Research 2011 May;70(1):2-8
Wen-Bo Lu1, Huan Ma1, Zu-Hang Sheng, Sumiko Mochida.Dynamin and activity regulate synaptic vesicle recycling in sympathetic neurons.Journal of Biological Chemistry 2009 Jan 16;284(3):1930-7
Huan Ma, Qian Cai, Wen-Bo Lu, Zu-Hang Sheng, Sumiko Mochida. KIF5B Motor Adaptor Syntabulin Maintains Synaptic Transmission in Sympathetic Neurons. The Journal of Neuroscience, October 14, 2009, 29(41):13019-13029
Huan Ma and Sumiko Mochida. A cholinergic model synapse to elucidate protein function at presynaptic terminals.Neuroscience Research2007 Apr; 57(4):491-8