Work and Publications

1. PhD Thesis : Spectral Methods for Hamiltonian Systems and Their Applications  

2. An High-precision Numerical Method for the Dissipative Dynamics of the Hamiltonian System , J. An, L. Zhao and W. Zhang, International Journal of Computer Mathematics, Published online 10 Dec 2019

3. Some New Developments of Polynomial Preserving Recovery on Hexagon and Chevron Patterns , H. Pan, Z. Zhang and L. Zhao (Corresponding author), International Journal of Numerical Analysis and Modeling, Volume 17, Number 3, Copyright transferred 02 April 2020. 

4. A Novel Energy Sequence Optimization Algorithm for Efficient Spot-Scanning Proton Arc Treatment Delivery , G. Liu, X.Li, L. Zhao, X. Ding etc, Acta Oncologica, Published online 18 May 2020.

5. Feasibility study: spot-scanning proton arc therapy (SPArc) for left-sided whole breast radiotherapy , S. Chang, G. Liu, L. Zhao and X.Ding etc, Radiation Oncology, Published 7 Oct 2020. 

6.Investigation of instability in ultrasonic welding under parametric excitation , Y. He and L. Zhao, The International Journal of Electrical Engineering & Education, Published online Jan 14 2021. 

7. Is proton beam therapy ready for single fraction spine SBRS? – a feasibility study to use spot-scanning proton arc (SPArc) therapy to improve the robustness and dosimetric plan quality , G. Liu, X. Li, A. Qin, J. Zhou, W. Zheng, L. Zhao and X.Ding ect, Acta Oncologica, Published online 27 Feb 2021. 

8. Regularity and finite element approximation for two-dimensional elliptic equations with line Dirac sources ,  H. Li, X. Wan, P. Yin and L. Zhao,  Journal of Computational and Applied Mathematics, Available online 3 March 2021.

9. Lung Stereotactic Body Radiotherapy (SBRT) Using Spot-Scanning Proton Arc (SPArc) Therapy: A Feasibility Study, G. Liu, L.Zhao and X.Ding etc, Frontiers in Oncology, Accepted 26 Mar 2021.

10. Two-parameter localization and related phase transition for a Schrodinger operator in balls and spherical shells, C.Jia, Z.Zhang and L.Zhao (Corresponding author), Journal of Mathematical Physics, Accepted on Aug 16 2021. 

11. Building a precise machine-specific time structure of the spot and energy delivery model for a cyclotron-based proton therapy system , L.Zhao et al,  Physics in Medicine & Biology, Accepted online 14 December 2021. 

12. Developing an accurate model of spot-scanning treatment delivery time and sequence for a compact superconducting synchrocyclotron proton therapy system , L.Zhao et al,  Radiation Oncology,  Published: 07 May 2022.

13. Treatment planning in arc proton therapy: Comparison of several optimization problem statements and their corresponding solvers , S.Wuycken, M.Saint-Guillainb, G.Janssens, L.Zhao et al, Computers in Biology and Medicine, Available online 13 May 2022.

14. Redefine the Role of Spot-Scanning Proton Beam Therapy for the Single Brain Metastasis Stereotactic Radiosurgery , S. Chang, G. Liu, L. Zhao et al, Frontiers in Oncology, 19 May 2022.

15. An evolutionary optimization algorithm for proton arc therapy , L.Zhao (Corresponding author) et al, Physics in Medicine & Biology, Accepted Manuscript online 25 July 2022.

16. Establish a comprehensive plan robustness evaluation platform for intensity modulated proton therapy for bilateral head and neck cancer based on the daily cone-beam computed tomography: a dose accumulation study between the PTV based IMPT (PTV-IMPT) and CTV based robust optimized IMPT (ro-IMPT) planning strategies , W. Wang, A. Qin, X. Li,  J. Zhou, D. Yan, G. Liu, L. Zhao et al, Therapeutic Radiology and Oncology, Published: 30 September 2022.

17. Bi-criteria Pareto optimization to balance irradiation time and dosimetric objectives in proton arc therapy , S. Wuycken, L. Zhao et al, Physics in Medicine & Biology, Accepted online 24 November 2022. 

18. Introduce a rotational robust optimization framework for Spot-scanning ProtonArc(SPArc) therapy , S. Chang, G. Liu, L.Zhao et al, Physics in Medicine & Biology, Accepted online 2 Dec 2022.

19. Ultra-fast, high spatial resolution single-pulse scintillation imaging of synchrocyclotron pencil beam scanning proton delivery , M. Clark, X. Ding, L. Zhao et al, Physics in Medicine & Biology, Accepted online 30 Jan 2023.

20. The first direct method of spot sparsity optimization for proton arc therapy , L.Zhao et al, Acta Oncologica, Published online 2 Feb 2023.

21.A novel ultra-high dose rate proton therapy technology: spot-scanning proton arc therapy FLASH (SPLASH) , G. Liu, L. Zhao et al, Red Journal, Published: May 15, 2023.

22. The first investigation of spot-scanning proton arc (SPArc) delivery time and accuracy with different delivery tolerance window settings , G. Liu, L. Zhao (equal contribute to first author) et al, Physics in Medicine & Biology, Accepted online 29 Sep 2023

23. Development of a standalone delivery sequence model for proton arc therapy , G. Liu, L. Zhao (equal contribute to first author) et al,  Medical Physics, published 08 Dec 2023. 

24. First direct machine-specific parameters incorporated in Spot-scanning Proton Arc (SPArc) optimization algorithm , G. Liu, Q. Fan, L. Zhao et al, Medical Physics, published 10 Feb ,2024.

25. Optimizing linear energy transfer distribution in intensity-modulated proton therapy using the alternating direction method of multipliers , Q. Fan, X. Zhang, R. Dao, Y. Qian, L. Zhao et al,  Frontiers in Oncology, 27 February 2024.