Publications

• Kim, S.; Lee, K.; Lim, S.; Lee, Y.* "Cu/Pd-Catalyzed Ligand-Controlled Regiodivergent Hydroarylation of Allenes Using Diisobutylaluminum Hydride" Org. Lett. 2025, 27, 12945-12950 (DOI: 10.1021/acs.orglett.5c04396)

• Park, C. H.; Lim, S.; Jung, B.*; Lee, Y.* "Regioselective Formal Hydroamidation of Alkynes: Synthesis of α-Substituted Acrylamides" Eur. J. Org. Chem. 2025, 28, e202401484 (DOI: 10.1002/ejoc.202401484)

• Lim, S.; Kim, T.; Lee, Y.* "Regioselective formal hydrocyanation of allenes: synthesis of  β,γ-unsaturated nitriles with α-all-carbon quaternary centers" Beilstein J. Org. Chem. 2025, 21, 800–806  (DOI:10.3762/bjoc.21.63) 

• Kim, M.; Kim, S.; Lee, Y.; Lee, Y.*; Seo, S.*; Jung, B.* "Synthesis of (Z)-Allylsilanes by Cu-Catalyzed Regioselective Protosilylation of Allenes via Single-Electron Process" ACS catalysis 2025, 15, 2380-2388 (DOI: 10.1021/acscatal.4c07488 )

• Yoon, S.; Lim, S.; Cho, S.; Lee, Y.* "Cu-Catalyzed Hydrodechlorination of Unactivated Alkyl Chlorides Using Diisobutylaluminum Hydride" Org. Lett. 2024, 26, 9943-9948 (DOI: 10.1021/acs.orglett.4c03774 )

• Lee, K.; Cho, S.; Lim, S.; Lee, Y.* "Access to α-all-carbon quaternary amides through the hydroamidation of allenes using DIBAL-H and isocyanates" Org. Chem. Front. 2024, 11, 1366-1371 (DOI: 10.1039/d3qo01855e)

• Lee, H.; Lee, Y.; Lee, Y.; Kamranifard, T.; Lee, Y.*; Jung, B.* "Cu-Catalyzed Synthesis of 2‑Silyl-1,3-butadienes from Allenols and Applications to One-Pot Synthesis of Tetrasubstituted Arylsilanes" Org. Lett. 2023, 25, 8932-8936 (DOI: 10.1021/acs.orglett.3c03794)

• Lee, S.; Lee, Y.* "Synthesis of α-Quaternary Carboxylic Acids through Cu-Catalyzed Hydrocarboxylation of Allenes with Diisobutylaluminum Hydride and Carbon Dioxide" Adv. Synth. Catal. 2023, 365, 4641-4646 (DOI: 10.1002/adsc.202300825)

• Lee, Y.; Lee, H.; Lee, Y.; Cho, S.; Lee, J.; Kang, J.; Jung, B.*; Lee, Y.* "Synthesis of α-Borylmethyl-(E)-allylborons via Cu-Catalyzed Diboration of 1-Substituted Allenols and Their Application in Stereoselective Aldehyde Allylation"  ACS Catalysis 2023, 13, 2351-2358 (DOI: 10.1021/acscatal.2c06061)

• Yoon, S.; Lee, K.; Kamranifard, T.; Lee, Y* "Synthesis of β,γ-unsaturated ketones with quaternary centersthrough regioselective hydroacylation of allenes with acylchlorides" Bull. Kor. Chem. Soc. 2022, 43, 1307-1311 (DOI: 10.1002/bkcs.12629).

• Yoon, S.; Lee, S.; Nam, S. H.; Lee, H.; Lee, Y.* "Synthesis of N-substituted quaternary carbon centers through KOt-Bu-catalyzed aza-Michael addition of pyrazoles to cyclic enones" Org. Biomol. Chem. 2022, 20, 8313-8322 (DOI: 10.1039/d2ob01634f).

• Kim, K.; Lee, Y.* "Copper-Catalyzed Hydroamination of Oxa- and Azabenzonorbornadienes with Pyrazoles" J. Org. Chem. 2022, 87, 569-578.

• Cho, S.; Lee, Y.; Lee, K.; Lee, H.; Lee, Y.*; Jung, B.* "Synthesis of alkynamides through reaction of alkyl- or aryl-substituted alkynylaluminums with isocyanates" Org. Biomol. Chem. 2022, 20, 139-151.

• Kim, K.; Cho, S.; Park, S.; Lee, Y.* "Copper-catalyzed Regioselective Hydroaminations of Allylic Sulfones With Aromatic Amines" Bull. Kor. Chem. Soc. 2021, 42, 699-708.

• Kim, K.; Park, S.; Lee, Y.*  "KOt‐Bu‐Catalyzed Chemo‐ and Regioselective Hydroamination of Allylic Sulfones with Indoles" Eur. J. Org. Chem. 2021, 1, 125-137.

• Cho, H. J.; Kim, S. W.; Kim, S.; Lee, S.; Lee, J.; Cho, Y.; Lee, Y.; Lee, T.-W.; Shin, H.-J.; Song, C.* "Suppressing π–π stacking interactions for enhanced solid-state emission of flat aromatic molecules via edge functionalization with picket-fence-type groups" J. Mater. Chem. C 2020, 8, 17289-17296.

• Yang, W. S.; Kim, H. G.; Lee, Y.; Yoon, K.; Kim, S.; Kim, J. H.; Cho, J. Y.*  "Isoprenylcysteine carboxyl methyltransferase inhibitors exerts antiinflammatory activity" Biochem. Pharmacol. 2020, 182, 114219.

• Jeong, S.; Lee, S.; Kim, K.; Lee, Y.; Lee, J.; Oh, S.; Choi, J.-W.; Kim, S. W.; Hwang, K.-C.; Lim, S.* " Isoliquiritigenin Derivatives Inhibit RANKL-Induced Osteoclastogenesis by Regulating p38 and NF- B Activation in RAW264.7 Cells" Molecules 2020, 25, 3908.

• Lee, H.; Cho, S.; Lee, Y.*; Jung, B.* "Stereoselective Formal Hydroamidation of Si-Substituted Arylacetylenes with DIBAL‑H and Isocyanates: Synthesis of (E)- and (Z)‑α-Silyl-α,β-unsaturated Amides" J. Org. Chem. 2020, 85, 12024-12035.

• Lee, S.; Lee, S.; Lee, Y.* "Copper-Catalyzed Hydroalumination of Allenes with Diisobutylaluminum Hydride: Synthesis of Allylic Ketones with α-Quaternary Centers via Tandem Allylation/Oppenauer Oxidation" Org. Lett. 2020, 22, 5806-5810.

• Yang, W. S.; Kim, H. G.; Kim, E.; Han, S. Y.; Aziz, N.; Yi, Y.; Kim, S.; Lee, Y.; Yoo, B. C.;  Han, J.-W.; Parameswaran, N.; Kim, J. H.; Cho, J. Y.* "Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses" Cells 2020, 9, 1216-1244.

• Park, S.; Lee, H.; Lee, Y.* "Copper-Catalyzed Regio- and Stereoselective 1,6-Conjugate Addition of Aza-Heterocycles to 1-Sulfonyl-1,3-dienes" Adv. Synth. Catal. 2020, 362, 572-584.

• Kim, H. B.; Lee, S.; Shen, Y.; Ryu, P.-D.; Lee, Y.; Chung, J. H.; Sung, C. K.; Baik, K. Y.* "Physicochemical factors that Affect Electroporation of Lung Cancer and Normal Cell Lines" Biochemical and Biophysical Research Communications 2019, 517, 703-708.

• Lee, S.; Lee, Y* "Copper-Catalyzed Electrophilic Amination of Benzoxazoles via Magnesation" Eur. J. Org. Chem. 2019, 3045-3050.

• Park, S.; Kang, S.; Lee, Y* "Copper-Catalyzed Intermolecular Hydroamination of Arylamines or Aza-Heterocycles with Nitrostyrene Derivatives" Adv. Synth. Catal. 2019, 361, 1071-1083 

• Kim, Y.; Lee, H.; Park, S.; Lee, Y* " Copper-Catalyzed Propargylic Reduction with Diisobutylaluminum Hydride" Org. Lett.2018, 20, 5478-5481.

• Kang, S.; Park, S.; Kim, K.-s.; Song, C.; Lee, Y* "Copper-Catalyzed Aza-Michael Addition of 2-Aminobenzoate to β-Substituted α,β-Unsaturated Ketones: One-Pot Synthesis of 3-Carbonyl-2-Substituted Quinolin-4(1H)-ones" J. Org. Chem.2018, 83, 2694-2705.

• Mun, B.; Kim, S.; Yoon, H.; Kim, K. H.; Lee, Y.* "Total Synthesis of Isohericerin, Isohericenone, Erinacerin A: Development of a Copper-Catalyzed Methylboronation of Terminal Alkynes" J. Org. Chem. 2017, 82, 6349‒6357.

• Yoon, H.; Kim, Y.; Lee, Y.* "Cu-catalyzed electrophilic amination of internal alkynes via hydroalumination" Org. Biomol. Chem. 2017, 15, 790‒795.

     (*Highlighted in Synfacts 2017, 294. "Amination of Internal Alkynes")

• Kang, S.; Yoon, H.; Lee, Y.* "One-pot Synthesis of Highly Functionalizable 3-(Phenylsulfonyl)-2,3-dihydro-4(1H)-quinolinones via a Cu-catalyzed Aza-Michael Addition/Cyclization Reaction" Chem. Lett. 2016, 45, 1356‒1358.

• Mun, B.; Park, Y. J.; Sung, G. H.; Lee, Y.*; Kim, K. H.* " Synthesis and antitumor activity of (-)-bassianolide in MDA-MB 231breast cancer cells through cell cycle arrest" Bioorg. Chem. 2016, 69, 64‒70.

•  Jeong, D.-C.; Mun, B.; Lee, H.; Hwang, S. J.; Yoo, S. J.; Cho, E.; Lee, Y.*; Song, C.* “Binaphthyl-based molecular barrier materials for phosphoric acid poisoning in high-temperature proton exchange membrane fuel cells” RSC Advances 2016, 6, 60749‒60755.

• Kim, S.; Kang, S.; Kim, G.; Lee, Y.* “Copper-Catalyzed Aza-Michael Addition of Aromatic Amines or Aromatic Aza-Heterocycles to α,β-Unsaturated Olefins” J. Org. Chem. 2016, 81, 4048‒4057.

• Kim, J. H.; Lee, Y.; Kim, M.-Y.; Cho, J. Y. “4-(Tert-butyl)-2,6-bis(1-phenylethyl)phenol induces pro-apoptotic activity” Korean J. Physiol. Pharmacol. 2016, 20, 253‒259.

• Sung, N. Y.; Kim, S. C.; Kim, Y. H.; Kim, G.; Lee, Y.; Sung, G.-H.; Kim, J. H.; Yang, W. S.; Kim, M. S.; Baek, K.-S.; Kim, J.-H.; Cho, J. Y. “Anti-Proliferative and Pro-Apoptotic Activities of 4-Methyl-2,6-bis(1-phenylethyl)phenol in Cancer Cells”  Biomol. Ther. 2016, 24, 402‒409.

• Kim, K-s.; Cha, I.; Cho, D.; Ahn, J.; Satheeshkumar, C.; Lee, J. Y.; Lee, Y.; Song, C. "Torsionally Responsive Tropone-Fused Conjugated Polymers" Macromolecules 2015, 48, 7015−7023.

• Yang, W. S.; Ratan, Z. A.; Kim, G.; Lee. Y.; Kim, M-Y.; Kim, J-H.; Cho, J. Y. "4-Isopropyl-2,6-bis(1-phenylethyl)aniline 1, an Analogue of KTH-13 Isolated from Cordyceps Bassiana, Inhibits the NF-kappaB-mediated Inflammatory Response" Mediat. Inflamm. 2015, Article ID 143025.

• Yoon, H.; Lee, Y. “Copper-Catalyzed Electrophilic Amination of Heteroarenes via C−H Alumination” J. Org. Chem. 2015, 80, 10244−10251.

• Jeong, D-C.; Song, S. G.; Satheeshkumar , C.; Lee, Y.; Kim, K-s.; Song, C. “Enhanced photoinduced electron transfer by multiwalled carbon nanotubes in self-assembled terpyridine polymer networks” Polymer 2015, 69, 39‒44.

• Kim, M. S.; Lee, Y.; Sung, G-H.; Kim, J. H.; Park, J. G.; Kim, H. G.; Baek, K. S.; Cho, J. H.; Han, J.; Lee, K-H.; Hong, S.; Kim, J-H.; Cho, J. Y. “Pro-Apoptotic Activity of 4-Isopropyl-2-(1-Phenylethyl)Aniline Isolated from Cordyceps bassiana” Biomol. Ther. 2015, 23, 367‒373.

• Jeong, D-C.; Lee, J.; Lee, Y.; Satheeshkumar, C.; Song, C. “Enhancement of Photoinduced Electron Transfer in Self-Assembled Polymer Films Using Mixed Metal–Terpyridine Complexes” Macromolecules 2015, 48, 1621‒1626.

• Kim, J. H.; Lee, Y.; Sung, G-H.; Kim, H. G.; Jeong, D.; Park, J. G.; Baek, K-S.; Sung, N. Y.; Yang, S.; Yoon, D. H.; Lee, S. Y.; Kang, H.; Song, C.; Cho, J. H.; Lee, K-H.; Kim, T. W.; Cho, J. Y. “Antiproliferative and Apoptosis-Inducing Activities of 4-Isopropyl-2,6-bis(1-phenylethyl)phenol Isolated from Butanol Fraction of Cordyceps bassiana” Evidence-Based Complementary and Alternative Medicine 2015, 1‒10.

• Song, S. G.; Satheeshkumar, C.; Park, J.; Ahn, J.: Premkumar, T.; Lee, Y.; Song, C. “N-Heterocyclic Carbene-Based Conducting Polymer-Gold Nanoparticle Hybrids and Their Catalytic Application” Macromolecules 2014, 47, 6566‒6571.

• Lee, H.; Cha, I.; Lee, E. J.; Lee, Y.; Kim, Y. H.; Song, C. “Annulated Borepin-1ol: Coordinative Control of Aromaticity and Photophysical Properties” Chem. Lett. 2014, 43, 1432‒1434.

• Jeong, D.; Yi, Y-S.; Sung, G-H.; Yang, W. S.’ Park, J. G.; Yoon, K.; Yoon, D. H.; Song, C.; Lee, Y.; Rhee, M. H.; Kim, T. W.; Kim, J-H.; Cho, J. Y. “Anti-inflammatory activities and mechanisms of Artemisia asiatica ethanol extract” J. Ethnopharmacol. 2014, 152, 487‒496.

• Dung, T. T.; Kim, S. C.; Yoo, B. C.; Sung, G-H.;  Yang, W. S.;  Kim, H. G.; Park, J. G.; Rhee, M. H.; Park, K.; Yoon, K.; Lee, Y.; Hong, S.; Kim, J-H.; Cho, J. Y. “(5-Hydroxy-4-oxo-4H-pyran-2-yl)methyl 6-hydroxynaphthalene-2-carboxylate, a kojic acid derivative, inhibits inflammatory mediator production via the suppressionof Syk/Src and NF-κB activation” Int. Immunopharmacol. 2014, 20, 37‒45.

• Lee, Y.; Umeano, A.; Balskus, E. P. "Rescuing Auxotrophic Microorganisms with Nonenzymatic Chemistry" Angew. Chem. Int. Ed. 2013, 52, 11800‒11803.

2012 and earlier

• • Lee, Y.; Klausen, R. S.; Jacobsen, E. N. "Thiourea-Catalyzed Enantioselective Iso-Pictet-Spengler Reactions" Org. Lett. 2011, 13, 5564-5567.

• • Jang, H.; Zhugralin, A. R.; Lee, Y.; Hoveyda, A. H. "Highly Selective Methods for Synthesis of Internal (a-) Vinylboronates through Efficient NHC-Cu-Catalyzed Hydroboration of Terminal Alkynes. Utility in Chemical Synthesis and Mechanistic Basis for Selectivity" J. Am. Chem. Soc. 2011, 133, 7859-7871.

• • Gao, F.; Lee, Y.; Mandai, K.; Hoveyda, A. H. "Quaternary Carbon Stereogenic Centers through Copper-Catalyzed Enantioselective Allylic Substitutions with Readily Accessible Aryl- or Heteroaryllithium Reagents and Aluminum Chlorides" Angew. Chem. Int. Ed. 2010, 49, 8370-8374.

    • (*Highlighted in Synfacts 2011, 186. "Copper-Catalyzed Asymmetric Allylic Substitution with Arylaluminum Reagents")

• • Gao, F.; McGrath, K. P.; Lee, Y.; Hoveyda, A. H. "Synthesis of Quaternary Carbon Stereogenic Centers through Enantioselective Cu-Catalyzed Allylic Substitutions with Vinylaluminum Reagents" J. Am. Chem. Soc. 2010, 132, 14315-14320.

• • Lee, Y.; Jang, H.; Hoveyda, A. H. "Vicinal Diboronates in High Enantiomeric Purity through Tandem Site-Selective NHC-Cu-Catalyzed Boron-Copper Additions to Terminal Alkynes" J. Am. Chem. Soc. 2009, 131, 18234-18235.

    • (*Highlighted in Synfacts 2010, 331. "Synthesis of Vicinal Diboronates by Cu(I)-Catalyzed B-Cu Addition to Alkynes")

• • Lee, Y.; Li, B.; Hoveyda, A. H. "Stereogenic-at-Metal Zn- and Al-Based N-Heterocyclic Carbene (NHC) Complexes as Bifunctional Catalysts in Cu-Free Enantioselective Allylic Alkylations" J. Am. Chem. Soc. 2009, 131, 11625-11633.

• • Lee, Y.; Hoveyda, A. H. "Efficient Boron-Copper Additions to Aryl-Substituted Alkenes Promoted by NHC-Based Catalysts. Enantioselective Cu-Catalyzed Hydroboration Reactions" J. Am. Chem. Soc. 2009, 131, 3160-3161.

    • (*Highlighted in ChemCatChem 2009, 1, 233-235, Guiry, P. J. "Expanding the Substrate Scope for Metal-Catalyzed Asymmetric Carbon-Boron Bond Formation"; Synfacts 2009, 625. "Copper-NHC Catalysts for Hydroboration"; JACS Select #6)

• • Lee, Y.; Akiyama, K.; Gillingham, D. G.; Brown, M. K.; Hoveyda, A. H. "Highly Site- and Enantioselective Cu-Catalyzed Allylic Alkylation Reactions with Easily Accessible Vinylaluminum Reagents" J. Am. Chem. Soc. 2008, 130, 446-447.

    • (*Highlighted in Synfacts 2008, 267. "Catalytic Asymmetric Allylic Alkylation with Vinylaluminum Reagents")

• • Lee, Y.;Hoveyda, A. H. "Lewis Base Activation of Grignard Reagents with N-Heterocyclic Carbenes. Cu-Free Catalytic Enantioselective Additions to γ-Chloro-α,β-Unsaturated Esters" J. Am. Chem. Soc. 2006, 128, 15604-15605.

• • Kang, S. H.; Lee, Y. "A Formal Total Synthesis of (-)-Dysiherbaine" Synlett 2003, 993-994.