一、期刊論文:
Chong KY, Tseng CP and Tsai WC. The susceptibility pattern of fifteen common clinical bacteria against different Cephalosporins. J Biomed Lab Sci (Taiwan) 2: 12-23, 1989.
Choo KB, Chong KY, Chou HF, Liew LN, Liou CC. Analysis of the structure and expression of the c-myc oncogene in cervical tumor and in cervical tumor-derived cell lines. Biochem Biophys Res Commun. 158: 334-40, 1989.
Choo KB, Lee HH, Liew LN, Chong KY, Chou HF. Analysis of the unoccupied site of an integrated human papillomavirus 16 sequence in a cervical carcinoma. Virology. 178: 621-5, 1990.
Choo KB, Liew LN, Chong KY, Lu RH, Cheng WT. Transgenome transcription and replication in the liver and extrahepatic tissues of a human hepatitis B virus transgenic mouse. Virology. 182: 785-92, 1991.
Choo KB, Chong KY, Liew LN , Hsu HC, Cheng WT. Unregulated and basal transcriptional activities of the regulatory sequence of the type 18 human papillomavirus genome in transgenic mice. Virology. 188: 378-83, 1992.
Choo KB, Chong KY. Absence of mutation in the p53 and the retinoblastoma susceptibility genes in primary cervical carcinomas. Virology. 193: 1042-6, 1993.
Chong K, Chen CM, Choo KB. Post-hybridization recovery of membrane filter-bound DNA for enzymatic DNA amplification. Biotechniques .14: 575-8, 1993.
Su C-Y, Chong KY, Owen OE, Dillmann WH, Chang C, Lai C-C. Constitutive and inducible HSP70s are involved in oxidative resistance evoked by heat shock or ethanol. J Mol Cell Cardiol. 30: 587-98, 1998.
Chong KY, Lai C-C, Lille S, Chang C and Su C-Y. Stable Overexpression of the Constitutive Form of Heat Shock Protein 70 Confers Oxidative Protection. J Mol Cell Cardiol. 30: 599-608, 1998.
Su C-Y, Chong KY, Chen JX, Ryter S, Lai C-C. A Physiologically Relevant Hyperthermia Selectively Avtivates Constitutive hsp 70 in H 9c 2 Cardiac Myoblasts and Confers Oxidative Protection. J Mol Cell Cardiol. 31: 845-55, 1999.
Su C-Y, Chong KY, Edelstein KM, Lille S, Khardori R, Lai C-C. Costitutive hsp70 Attenuates Hydrogen Peroxide-induced Mmembrane Lipid Peroxidation. Biochem Biophys Res Commun. 265; 279-84, 1999.
Chan AWS, Chong KY, Martinovich C, Simerly C, Schatten G. Transgenic monkeys produced by retroviral gene transfer into mature oocytes. Science. 291, 309-12, 2001.
Cabot RA, Kuhholzer B, Chan AWS, Lai L, Park KW, Chong KY, Schatten G, Murphy CN, Abeydeera L, Day BN and Prather RS. Transgenic Pigs produced using In Vitro matured Oocytes infected with a Retroviral Vector. Animal Biotechnology. 12: 205-14, 2001.
Chan AW, Chong KY, Schatten G. Transgenic bovine embryo selection using green fluorescent protein. Methods in molecular biology. 183: 201-14, 2002
Calvin Simerly, Tanja Dominko, Christopher Navara, Christopher Payne, Saverio Capuano, Gabriella Gosman, Chong KY, Diana Takahashi, Crista Chace, Duane Compton, Laura Hewitson, Gerald Schatten. Molecular correlates of primate nuclear transfer failures. Science. 300: 297, 2003.
Simerly C, Dominko T, Navara C,Payne C, Capuano S, Gosman G, Chong KY, Khorram O, Jones J, Mountain V, Compton D, Hewitson L and Schatten G. Primate Nuclear Transfer Failures: Defective Centrosomes Organize Faulty Mitotic Spindles Producing Aneuploid Embryos. Science. 300: 297, 2003.
Simerly C, Navara C, Hyun SH, Lee BC, Kang SK, Capuano S, Gosman G, Dominko T, Chong KY, Compton D, Hwang WS, & Schatten G. Embryogenesis And Blastocyst Development After Somatic Cell Nuclear Transfer In Non-Human Primates (Nhp-Scnt): Overcoming Defects Caused By Meiotic Spindle Extraction . Dev Biol. 276: 237-52, 2004.
Tseng CP, Huang CL, Chong KY, Hung IJ, Chiu DTY. Rapid detection of glucose-6-phosphate dehydrogenase gene mutations by denaturing high-performance liquid chromatography. Clin Biochem. 38: 973-80, 2005.
Choo KB, Hsu MC, Chong KY, Huang CJ. Testis-specific expression and genomic multiplicity of the rat Rtdpoz genes that encode bipartite TRAF- and POZ/BTB-domain proteins. Gene. 387: 141-9, 2007.
Liu FC, Chen HL, Chong KY, Hsu AL, Chen CM. Production of recombinant porcine colipase secreted by Pichia Patoris and its application to improve dietary fat digestion and growth of postweaning Piglets. Biotechnol Prog. 24, 1333-41, 2008.
Yen CC*, Lin CY*, Chong KY*, Tsai TC, Shen CJ, Lin MF, Su CY, Chen HL and Chen CM. Lactoferrin as a natural regimen of selective decontamination of the digestive tract: recombinant porcine Lactoferrin expression in the milk of transgenic mice protects neonates from pathogen challenges in the gastrointestinal tract. J Inf Dis. 199: 590-8, 2009. hese authors make equal contribution to this paper.
Tseng WL, Huang CL, Chong KY, Liao CH, Stern A, Cheng JC, Tseng CP. Reelin is a platelet protein and functions as a positive regulator of platelet spreading on fibrinogen. Cell Mol Life Sci. 67: 641-53, 2010.
Huang CL, Cheng JC, Kitajima K, Nakano T, Yeh CF, Chong KY* , Tseng CP*. Disabled-2 is required for mesoderm differentiation of murine embryonic stem cells. J Cell Physiol . 225: 92-105, 2010.
Tsai TC, Lin W, Yang SH, Cheng WT, Cheng EH, Lee MS, Chong KY, Chen CM. Granzyme G is expressed in the two-cell stage mouse embryo and is required for the maternal-zygotic transition. BMC Dev Biol. 2011: 238208, 2011.
Hung CM, Chen, HL, Chong KY, Chia-Chou Yeh CC, Kao ST, Yeh HM Lin MS, and Chen CM. Gingyo-San Enhances Immunity and Assists Infectious Bursal Disease Vaccination. Evidence-based Compl and Alt Medicine. 2011: 238208, 2011.
Chong KY, Lai CC, Su CY. Inducible and Constitutive HSP70s confer a synergistic resistance against oxidative insults. Biochem Biophys Res Commun. 430: 774-9, 2013.
Huang TT, Chong KY, Ojcius DM, Wu YH, Ko YF, Wu CY, Martel J, Lu CC, Lai HC, Young JD. Hirsutella sinensis mycelium suppresses interleukin-1β and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes. Sci Rep. 3: 1374, 2013.
Chen W, Chen JY, Tung YT, Chen HL, Kuo CW, Chuang CH, Chong KY, Mao FC, Chen CM. High-frequency ultrasound imaging to evaluate liver fibrosis progression in rats and yi guan jian herbal therapeutic effects. Evid Based Complement Alternat Med. 2013: 302325, 2013.
Huang TT, Lai HC, Chen YB, Chen LG, Wu YH, Ko YF, Lu CC, Chang CJ, Wu CY, Martel J, Ojcius DM, Chong KY, Young JD. Cis-Resveratrol produces anti-inflammatory effects by inhibiting canonical and non-canonical inflammasomes in macrophages. Innate Immun. 20: 735-50, 2014.
Tung YT, Tang TY, Chen HL, Yang SH, Chong KY, and Chen CM. Lactoferrin protects against chemical-induced rat liver fibrosis through inhibiting stellate cells activation. J Dairy Sci. 97: 3281-91, 2014.
Hung TH, Chen CM, Tseng CP, Shen CJ, Wang HL, Choo KB, Chong KY#. FZD1 activates protein kinase C delta-mediated drug-resistance in multidrug-resistant MES-SA/Dx5 cancer cells. Int J Biochem Cell Biol. 53: 55-65, 2014.
Lai CW, Chen HL, Lin KY, Liu FC, Chong KY, Cheng WT, Chen CM. FTSJ2, a heat shock-inducible mitochondrial protein, suppresses cell invasion and migration. PLoS One. 9: e90818, 2014.
Hung TH, Hsu SC, Cheng CY, Choo KB, Tseng CP, Chen TC, Lan YW, Huang TT, Lai HC, Chen CM, Chong KY#. Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway. Oncotarget. 5: 12273-90, 2014.
Huang TT, Wu SP, Chong KY, Ojcius DM, Ko YF, Wu YH, Wu CY, Lu CC, Martel J, Young JD, Lai HC. The medicinal fungus Antrodia cinnamomea suppresses inflammation by inhibiting the NLRP3 inflammasome. J Ethnopharmacol.155: 154-64, 2014.
Tsai TC, Tung YT, Kuo YH, Liao JW, Tsai HC, Chong KY, Chen HL, Chen CM. Anti-inflammatory effects of Antrodia camphorata, a herbal medicine, in a mouse skin ischemia model. J Ethnopharmacol. 159: 113-21, 2015.
Chong KY#, Hsu CJ, Hung TH, Hu HS, Huang TT, Wang TH, Wang C, Chen CM, Choo KB, Tseng CP. Wnt pathway activation and ABCB1 expression account for attenuation of Proteasome Inhibitor-mediated apoptosis in multidrug-resistant cancer cells. Cancer Biol Ther. 16: 149-59, 2015.
Tung YT, Huang PW, Chou YC, lai CW, Wang HP, Ho HC, Yen CC, Tu CY, Tsai TC, Yeh DC, Wang JL, Chong KY, Chen CM. Lung tumorigenesis induced by human vascular endothelial growth factor (hVEGF)-A165 overexpression in transgenic mice and amelioration of tumor. Oncotarget. 6: 10222-38, 2015.
Lin MH, Shu JC, Lin LP, Chong KY, Cheng YW, Du JF, Liu ST. Elucidating the Crucial Role of Poly N-Acetylglucosamine from Staphylococcus aureus in Cellular Adhesion and Pathogenesis. PLoS One. 10: e0124216, 2015.
Lan YW, Choo KB, Chen CM, Hung TH, Chen YB, Hsieh CH, Kuo HP, Chong KY#. Hypoxia-Preconditioned Mesenchymal Stem Cells Attenuates Bleomycin-Induced Pulmonary Fibrosis. Stem Cell Res Ther. 6: 97, 2015.
Hung TH, Li YH, Tseng CP. Lan YW, Hsu SC, Chen YH, Huang TT, Lai HC, Chen CM, Choo KB, Chong KY#. Knockdown of c-MET induced apoptosis in ABCB1-overexpressed multidrug-resistance cancer cell lines. Cancer Gene Ther. 22: 262-70, 2015.
Chen YB, Lan YW, Hung TH, Chen LG, Choo KB, Cheng WT, Lee HS, Chong KY#. Mesenchymal stem cell-based HSP70 promoter-driven VEGFA induction by resveratrol promotes angiogenesis in a mouse model. Cell Stress Chaperones. 20: 643-52, 2015.
Chen YB, Lan YW, Chen LG, Huang TT, Choo KB, Cheng WTK, Lee HS, Chong KY#. Mesenchymal stem cell-based HSP70 promoter-driven VEGFA induction by resveratrol alleviates elastase-induced emphysema in a mouse model. Cell Stress Chaperones. 20: 979-89, 2015.
Hsu CY, Shu JC, Lin MH, Chong KY, Chen CC, Wen SM, Hsieh YT, Liao WT. High Glucose Concentration Promotes Vancomycin-Enhanced Biofilm Formation of Vancomycin-Non-Susceptible Staphylococcus aureus in Diabetic Mice. PLoS One. 10: e0134852, 2015.
Huang TT, Lai HC, Ko YF, Ojcius DM, Lan YW, Martel J, Young JD, Chong KY#. Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo. Sci Rep. 5: 15282, 2015.
Chang YW, Hsieh PW, Chang YT, Lu MH, Huang TF, Chong KY, Liao HR, Cheng JC, Tseng CP. Identification of a novel platelet antagonist that binds to CLEC-2 and suppresses podoplanin-induced platelet aggregation and cancer metastasis. Oncotarget. 6: 42733-48, 2015.
Shih CL, Chong KY, Hsu SC, Chien HJ, Ma CT, Chang JW, Yu CJ, Chiou CC. Development of a magnetic bead-based method for the collection of circulating extracellular vesicles. N Biotechnol. 33: 116-22, 2016.
Lai CW, Chen HL, Tsai TC, Chu TW, Yang SH, Chong KY, Chen CM. Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling. Sci Rep. 6: 24023, 2016.
Chen YL, Hwang TL, Yu HP, Fang JY, Chong KY, Chang YW, Chen CY, Yang HW, Chang WY, Hsieh PW. Ilex kaushue and Its Bioactive Component 3, 5-Dicaffeoylquinic Acid Protected Mice from Lipopolysaccharide-Induced Acute Lung Injury. Sci Rep. 6: 34243, 2016.
Chang PY, Huang Y, Hung TY, Chong KY, Chang YS, Chao CC, Chow KN. Spontaneous metastases in immunocompetent mice harboring a primary tumor driven by oncogene latent membrane protein 1 from Epstein-Barr virus. Biomed J. 39: 261-71, 2016.
Lan YW, Theng SM, Huang TT, Choo KB, Chen CM, Kuo HP, Chong KY*. Oncostatin M-Preconditioned Mesenchymal Stem Cells Alleviate Bleomycin-Induced Pulmonary Fibrosis Through Paracrine Effects of the Hepatocyte Growth Factor. Stem Cells Transl Med. 6: 1006-17, 2017.
Lai CW, Chen HL, Tu MY, Lin WY, Röhrig T, Yang SH, Lan YW, Chong KY, Chen CM#. A novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice. Oncotarget. 8: 7357-69, 2017. #co-corresponding author
Chen YL, Hwang TL, Fang YF, Lan YH, Chong KY, Hsieh PW. Polysaccharides from Kochia scoparia fruits protect mice from lipopolysaccharide-mediated acute lung injury by inhibiting neutrophil elastase. J Funct Foods. 38: 582-90, 2017.
Tung YT, Chen HL, Wu HS, Ho MH, Chong KY, Chen CM. Kefir Peptides Prevent Hyperlipidemia and Obesity in High-Fat-Diet-Induced Obese Rats via Lipid Metabolism Modulation. Mol Nutr Food Res. 62(3). doi: 10.1002/mnfr.201700505, 2018
Chang YW, Tseng CP, Lee CH, Hwang TL, Chen YL, Su MT, Chong KY , Lan YW, Wu CC, Chen KJ, Lu FH, Liao HR, Hsueh C, Hsieh PW. β-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release. Am J Physiol Lung Cell Mol Physiol. 314: L654-69, 2018.
Huang TT, Lan YW, Ko YF, Chen CM, Lai HC, Ojcius DM, Martel J, Young JD, Chong KY. Antrodia cinnamomea produces anti-angiogenic effects by inhibiting the VEGFR2 signaling pathway. J Ethnopharmacol. 220: 239-49, 2018.
Hiew MSY, Cheng HP, Huang CJ, Chong KY, Cheong SK, Choo KB, Kamarul T. Incomplete cellular reprogramming of colorectal cancer cells elicits an epithelial/ mesenchymal hybrid phenotype. J Biomed Sci. 25: 57, 2018.
Lee IT, Lin CF, Huang YL, Chong KY, Hsieh MF, Huang TH, Cheng CY. Protective mechanisms of resveratrol derivatives against TNF-α-induced inflammatory responses in rat mesangial cells. Cytokine. 113: 380-92, 2018.
Huang TT, Lan YW, Chen CM, Ko YF, Ojcius DM, Martel J, Young JD, Chong KY*. Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells. Sci Rep. 9: 5145, 2019.
Lan YW, Yang JC, Yen CC, Huang TT, Chen YC, Chen HL, Chong KY*, Chen CM*. Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema. Stem Cell Res Ther. 10: 163, 2019.
Chen HL, Hung KF, Yen CC, Laio CH, Wang JL, Lan YW, Chong KY, Fan HC, Chen, CM. Kefir peptides alleviate particulate matter <4 μm (PM4.0)-induced pulmonary inflammation by inhibiting the NF-κB pathway using luciferase transgenic mice. Scientific Reports. 9: 11529, 2019.
Yen CC, Chang WH, Tung MC, Chen HL, Liu HC, Liao CH, Lan YW, Chong KY, Yang SH, Chen CM. Lactoferrin Protects Hyperoxia-Induced Lung and Kidney Systemic Inflammation in an In Vivo Imaging Model of NF-κB/Luciferase Transgenic Mice. Mol Imaging Biol. 22: 526-38, 2020.
Ou-Yang H, Wu SC, Sung LY, Yang SH, Yang SH, Chong KY, Chen CM. Article stat3 is an upstream regulator of granzyme g in the maternal-to-zygotic transition of mouse embryos. Int J Mol Sci. 22: 460, 2021
Lin SS, Niu CC, Yuan LJ, Tsai TT, Lai PL, Chong KY, Wei KC, Huang CY, Lu ML, Yang CY, Ueng SWN. Mir-573 regulates cell proliferation and apoptosis by targeting Bax in human degenerative disc cells following hyperbaric oxygen treatment. J Orthop Surg Res. 16: 16, 2021.
Tu MY, Han KY, Lan YW, Chang KY , Lai CW, Staniczek T, Lai CY, Chong KY*, Chen CM. Association of TGF-β1 and IL-10 Gene Polymorphisms with Osteoporosis in a Study of Taiwanese Osteoporotic Patients. Genes (Basel). 12(6): 930, 2021.
Huang CH# , Chong KY# , Lei KF. Analysis of the Internal Hypoxic Environment in Solid Tumor Tissue Using a Folding Paper System. ACS Appl Mater Interfaces. 13(29):33885-93, 2021
Wang JL, Tsai YT, Lin CH, Cidem A, Staniczek T, Chang GRL, Yen CC, Chen W, Chong KY*, Chen CM. Benefits of metformin combined with pemetrexed-based platinum doublets as a first-line therapy for advanced lung adenocarcinoma patients with diabetes. Biomolecules. 11(8): 1252, 2021.
Chen CF, Li HP, Chao YH, Tu MY, Yen CC, Lan YW, Yang SH, Chong KY*, Lin CC*, Chen CM*. Suppression of Dendritic Cell Maturation by Kefir Peptides Alleviates Collagen-Induced Arthritis in Mice. Frontiers in Pharmacology. 12: 721594, 2021.
Chen YC, Lan YW, Huang SM, Yen CC, Chen W, Wu WJ, Theresa Staniczek, Chong KY, Chen CM. Human amniotic fluid mesenchymal stem cells attenuate pancreatic cancer cell proliferation and tumor growth in an orthotopic xenograft mouse model. Stem Cell Res Ther. 13:235, 2022.
Liu YH, Chen YH, Ko CH, Kuo CW, Yen CC, Chen Wei, Chong KY*, and Chen CM*. SOD3 and IL-18 Predict the First Kidney Disease-Related Hospitalization or Death during the One-Year Follow-Up Period in Patients with End-Stage Renal Disease. Antioxidants. 11, 1198. 2022.
Wen YH, Lee CF, Chen YJ, Chang GJ* and Chong KY*. Risks in Induction of Platelet Aggregation and Enhanced Blood Clot Formation in Platelet Lysate Therapy: A Pilot Study. J Clin Med. 11: 3972, 2022.
Huang TT, Chen CM, Chen LG, Lan YW, Huang TH, Choo KB and Chong KY*. 2,3,5,4'-tetrahydroxystilbene -2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways. Frontiers in Pharmacology. 13: 997100, 2022.
Huang TT, Chen CM, Lan YW, Lin SS, Choo KB, Chong KY*. Blockade of c-Met-Mediated Signaling Pathways by E7050 Suppresses Growth and Promotes Apoptosis in Multidrug-Resistant Human Uterine Sarcoma Cells. Int J Mol Sci. 23: 14884, 2022.
Huang TT, Chen CM, Lin SS, Lan YW, Cheng HC, Choo KB, Wang CC, Huang TH, Chong KY*. E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways. Int J Mol Sci. 24(11): 9606, 2023.
Lin SS, Ueng SWN, Chong KY, Chan YS, Tsai TT, Yuan LJ, Liu SJ, Yang CY, Hsiao HY, Hsueh YJ, Chen CA, Niu CC. Effects of Hyperbaric Oxygen Intervention on the Degenerated Intervertebral Disc: From Molecular Mechanisms to Animal Models. Cells. 12(16): 2111, 2023.
Yen CC, Wu PY, Yang HO, Chen HL, Chong KY, Chang RL, Chen CM. Production of Bioactive Porcine Lactoferrin through a Novel Glucose-Inducible Expression System in Pichia pastoris: Unveiling Antimicrobial and Anticancer Functionalities. Int J Mol Sci. 25(3): 1818, 2024
Lana YW, Chen CE, Huang TT, Huang TH, Chene CM, Chong KY*. Antrodia Cinnamomea Extract Alleviates Bleomycin-induced Pulmonary Fibrosis in Mice by Inhibiting the mTOR Pathway. Biomedical Journal. 47(6): 100720, 2024
二、專書 :
Chan AWS, Chong KY and Schatten GP. Transgenic bovine embryo selection using green fluorescent protein. In: Hicks BW (ed) Green Fluorescent Protein: Method in Molecular biology 183. Humana Press, New Jersey, 2002, pp 201-214
Chan AWS, Chong KY and Schatten GP. Production of Transgenic Nonhuman Primates. In Pinkert CA (ed) Transgenic Animal Technology, 2nd edn. Academic Press, San Diego, 2002. pp 359-394.4.
Chan AWS, Chong KY and Schatten G. Transgenic Cattle: Bovine Embryo Selection Using GFP. Green Fluorescent Protein-Applications and Protocols (B W Hicks Ed.), Humana Press, Totowa , NJ , 2002.
Lan YW, Chen CM, Chong KY. In Vitro Methods to Evaluate the Effects of Mesenchymal Stem Cells on TGF-β1-Induced Pulmonary Fibrosis. In Vitro Models for Stem Cell Therapy. 2021, pp 83-92.