Publications

2019

[18]Neuroprotective effects of microglial P2Y1 receptors against ischemic neuronal injury

J Cereb Blood Flow Metab. 2019 Nov;39(11):2144-2156. doi: 10.1177/0271678X18805317.

Fukumoto Y, Tanaka KF, Parajuli B, Shibata K, Yoshioka H, Kanemaru K, Gachet C, Ikenaka K, Koizumi S, Kinouchi H.

2018

[17] Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes.

EBioMedicine. 2018 Jun;32:72-83. doi: 10.1016/j.ebiom.2018.05.036. Epub 2018 Jun 8.

Kinoshita M, Hirayama Y, Fujishita K, Shibata K, Shinozaki Y, Shigetomi E, Takeda A, Le HPN, Hayashi H, Hiasa M, Moriyama Y, Ikenaka K, Tanaka KF, Koizumi S.

2017

[16]Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation.

Cell Rep. 2017 May 9;19(6):1151-1164. doi: 10.1016/j.celrep.2017.04.047.

Shinozaki Y, Shibata K, Yoshida K, Shigetomi E, Gachet C, Ikenaka K, Tanaka KF, Koizumi S.

[15] P2Y6-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice.

Sci Rep. 2017 Apr 10;7(1):771. doi: 10.1038/s41598-017-00824-2.

Kira S, Yoshiyama M, Tsuchiya S, Shigetomi E, Miyamoto T, Nakagomi H, Shibata K, Mochizuki T, Takeda M, Koizumi S.

[14] Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa.

PLoS One. 2017 Jan 6;12(1):e0168234. doi: 10.1371/journal.pone.0168234.

Ihara T, Mitsui T, Nakamura Y, Kira S, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Andersson KE, Nakao A, Takeda M, Koizumi S.

2016

[13] Microglia contact induces synapse formation in developing somatosensory cortex.

Nat Commun. 2016 Aug 25;7:12540. doi: 10.1038/ncomms12540.

Miyamoto A, Wake H, Ishikawa AW, Eto K, Shibata K, Murakoshi H, Koizumi S, Moorhouse AJ, Yoshimura Y, Nabekura J.

[12] Urothelial ATP exocytosis: regulation of bladder compliance in the urine storage phase.

Sci Rep. 2016 Jul 14;6:29761. doi: 10.1038/srep29761.

Nakagomi H, Yoshiyama M, Mochizuki T, Miyamoto T, Komatsu R, Imura Y, Morizawa Y, Hiasa M, Miyaji T, Kira S, Araki I, Fujishita K, Shibata K, Shigetomi E, Shinozaki Y, Ichikawa R, Uneyama H, Iwatsuki K, Nomura M, de Groat WC, Moriyama Y, Takeda M, Koizumi S.

[11] An effective therapeutic approach for oxaliplatin-induced peripheral neuropathy using a combination therapy with goshajinkigan and sushi.

Cancer Biol Ther. 2016 Jul 14:0.

Mizuno K, Shibata K, Komatsu R, Omiya Y, Kase Y, Koizumi S.

[10]The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria.

Neurourol Urodyn. 2016 Jun 27. doi: 10.1002/nau.23062.

Ihara T, Mitsui T, Nakamura Y, Kira S, Miyamoto T, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Andersson KE, Nakao A, Takeda M, Koizumi S.

[Epub ahead of print]

PMID: 27348079

[9] Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain

J Clin. Invest. 2016 May 2;126(5):1983-97. doi: 10.1172/JCI82859. Epub 2016 Apr 11.

Kim SK, Hayashi H, Ishikawa T, Shibata K, Shigetomi E, Shinozaki Y, Inada H, Roh SE, Kim SJ, Lee G, Bae H, Moorhouse A, Fukazawa Y, Mikoshiba K, Koizumi S, Nabekura J.

2015

nothing

2014

[8] Mechanism Underlying ATP Release in Human Epidermal Keratinocytes.

J Invest Dermatol. 2013 Nov 29. doi: 10.1038/jid.2013.516.

Inoue K, Komatsu R, Imura Y, Fujishita K, Shibata K, Moriyama Y, Koizumi S.

2013

[7] Microglia release ATP by exocytosis.

Glia. 2013 Aug;61(8):1320-30. doi: 10.1002/glia.22517. Epub 2013 Jul 5.

Imura Y, Morizawa Y, Komatsu R, Shibata K, Shinozaki Y, Kasai H, Moriishi K, Moriyama Y, Koizumi S.

[6] Astrocytes Protect Neurons against Methylmercury via ATP/P2Y1 Receptor-Mediated Pathways in Astrocytes.

PLoS One. 2013;8(2):e57898. doi: 10.1371/journal.pone.0057898. Epub 2013 Feb 28.

Noguchi Y, Shinozaki Y, Fujishita K, Shibata K, Imura Y, Morizawa Y, Gachet C, Koizumi S.

[5] In vitro blood-brain barrier models using brain capillary endothelial cells isolated from neonatal and adult rats retain age-related barrier properties.

PLoS One. 2013;8(1):e55166. doi: 10.1371/journal.pone.0055166. Epub 2013 Jan 31.

Takata F, Dohgu S, Yamauchi A, Matsumoto J, Machida T, Fujishita K, Shibata K, Shinozaki Y, Sato K, Kataoka Y, Koizumi S.

2012

[4] Cell-Autonomous Enhancement of Glutamate-Uptake by Female Astrocytes.

Cell Mol Neurobiol. 2012 Mar 27. [Epub ahead of print]

Morizawa Y, Sato K, Takaki J, Kawasaki A, Shibata K, Suzuki T, Ohta S, Koizumi S.

2011