Submitted for publication
J. D. Challenger, J. Biggs, J. E. Skarp, J. Cook, T. S. Churcher: Combining statistical and dynamical modelling to guide the design of cluster randomised trials for malaria.
N. Chandradeva, E. Pretorius, E. Teixeira da Silva, H. Hutchins, F. Barri, I. Stopard, H. Soubrier, C. Martins, A. Rodrigues, J. E. Nante, P. Djata, J.D. Challenger, T.S. Churcher, E. Sherrard-Smith, A. Last: Simplifying mosquito sampling to estimate community biting exposure and malaria indoor vector control impact.
Publications
30) K. McCain, H. M. Topazian, J. D. Challenger, L.C. Okell, P. Winskill, A. C. Ghani: Public health impact of catch-up vaccination or additional booster doses with pre-erythrocytic malaria vaccine R21/Matrix-M: a modelling study. BMC Medicine (2026)
Journal (Open Access)
29) M. Tapsoba, W. M. Guelbeogo, A. Sanou, S. Zongo, C. Gogue, S. Debe, K. Arnett, K. Davis, J. Shannon, P. Digre, J. Mwesigwa, K. Tynuv, C. Fornadel, S. N’Falé, M. Robertson, J. D. Challenger, G. Tougri, A. Gansané, H. Ranson, G. Olivier, J, Wagman: Differential effects of dual and synergist-based insecticide-treated bed nets on pyrethroid resistance and L995F/S knockdown resistance mutation dynamics in Anopheles gambiae s.l. populations in south-western Burkina Faso. Parasites & Vectors (2025)
Journal (Open Access)
28) M. Tapsoba, W. M. Guelbeogo, A. Sanou, S. Zongo, C. Gogue, S. Debe, K. Arnett, K. Davis, J. Shannon, P. Digre, J. Mwesigwa, K. Tynuv, C. Fornadel, S. N’Falé, M. Robertson, J. D. Challenger, G. Tougri, A. Gansané, H. Ranson, G. Olivier, J Wagman: Three-year trends in malaria transmission parameters under deployment of Interceptor®G1, Interceptor®G2 and PermaNet®3.0 insecticide-treated bed nets in South-Western Burkina Faso. Malaria Journal (2025)
Journal (Open Access)
27) J. Biggs, J.D. Challenger, D. Dee, E. Elobolobo, C. Chaccour, F. Saute, S. Staedke, S. Vilakati, J. Benjamin-Chung, M. Hsiang, E. Dabira, A. Erhart, U. D’Alessandro, R. Tripura, T. Peto, L. von Seidlein, M. Mukaka, J. Mosha, N. Protopopoff, M. Accrombessi, R. Hayes, T. Churcher, J. Cook: Characterisation of between-cluster heterogeneity in malaria cluster randomised trials to inform future sample size calculations. Nature Communications (2025)
Journal (Open Access)
26) T. S. Churcher, I. J. Stopard, A. Hamlet, D. P. Dee, A. Sanou, M. Rowland, M. W. Guelbeogo, B. Emidi, J. F. Mosha, J. D. Challenger, A. Denz, A. Glover, G. D. Charles, E. L. Russell, R. Fitzjohn, P. Winskill, C. Fornadel, T. Mclean, P. Digre, J. Wagman, E. Sherrard-Smith: The epidemiological benefit of pyrethroid–pyrrole insecticide treated nets against malaria: an individual-based malaria transmission dynamics modelling study. The Lancet Global Health (2024)
Journal (Open Access)
25) J. Biggs, J. D. Challenger, J. Hellewell, T. S. Churcher, J. Cook: A systematic review of sample size estimation accuracy on power in malaria cluster randomised trials measuring epidemiological outcomes. BMC Medical Research Methodology (2024)
Journal (Open Access)
24) N. D. C. Djègbè, D. F. Da, B. M. Somé, L. I. G. Paré, F. Cissé, W. Mamai, K. Mouline, S. P. Sawadogo, J. D. Challenger, T. S. Churcher R. K. Dabiré: Anopheles aquatic development kinetic and adults’ longevity through different seasons in laboratory and semi-field conditions in Burkina Faso. Parasites & Vectors (2024)
Journal (Open Access)
23) M. M. Marjaneh, J. D. Challenger, A. Salas, A. Gómez-Carballa, A. Sivananthan, I. Rivero-Calle, G. Barbeito-Castiñeiras, C. Y. Foo, Y. Wu, F. Liew, H. R. Jackson, D. Habgood-Coote, G. D’Souza, S. J. Nichols, V. J. Wright, M. Levin, M. Kaforou, R. S. Thwaites, L. C. Okell, F. Martinón-Torres, A. J. Cunnington: Analysis of blood and nasal epithelial transcriptomes to identify mechanisms associated with control of SARS-CoV-2 viral load in the upper respiratory tract. Journal of Infection (2023)
Journal (Open Access)
22) W. Huang, J. Rodrigues, E. Bilgo, J. R. Tormo, J. D. Challenger, C. De Cozar-Gallardo, I. Pérez-Victoria, F. Reyes, P. Castañeda-Casado, E. J. Gnambani, D. F. de Sales Hien, M. Konkobo, B. Urones, I. Coppens, A. Mendoza-Losana, L. Ballell, A. Diabate, T. S. Churcher, M. Jacobs-Lorena: Delftia tsuruhatensis TC1 symbiont suppresses malaria transmission by anopheline mosquitoes. Science (2023)
21) J. D. Challenger, S. W. van Beek, R. ter Heine, S. C. van der Boor, G. D. Charles, M. J. Smit, C. Ockenhouse, J. J. Aponte, M. B. B. McCall, M. M. Jore, T. S. Churcher, T. Bousema: Modelling the impact of a highly potent Plasmodium falciparum transmission-blocking monoclonal antibody in areas of seasonal malaria transmission. Journal of Infectious Diseases (2023)
Journal (Open Access)
20) J. D. Challenger, R. K. Nash, C. Ngufor, A. Sanou, K. H. Toé, S. Moore, P. K. Tungu, M. Rowland, G. M. Foster, R. N’Guessan, E. Sherrard-Smith, T. S. Churcher: Assessing the variability in experimental hut trials evaluating insecticide-treated nets against malaria vectors. Current Research in Parasitology & Vector-Borne Diseases (2023)
Journal (Open Access)
19) L. C. Okell, T. K. Kwambai, A. Dhabangi, C. Khairallah, T. Nkosi-Gondwe, P. Winskill, R. Opoka, A. Mousa, M. Kühl, T. C. D. Lucas, J. D. Challenger, R. Idro, D. J. Weiss, M. Cairns, F. O. ter Kuile, K. Phiri, B. Robberstad, A. T. Mori: Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa. Nature Communications (2023)
Journal (Open Access)
18) J. D. Challenger, C. Y. Foo, Y. Wu, Ada W. C. Yan, M. Moradi Marjaneh, F. Liew, R. S. Thwaites, L. C. Okell, A. J. Cunnington: Modelling upper respiratory viral load dynamics of SARS-CoV-2. BMC Medicine (2022)
Journal (Open Access) Preprint link
17) C. Ngufor, J. Fagbohoun, A. Agbevo, H. Ismail, J. D. Challenger, T. S. Churcher and M. Rowland: Comparative efficacy of two pyrethroid-piperonyl butoxide nets (Olyset Plus and PermaNet 3.0) against pyrethroid resistant malaria vectors: a non-inferiority assessment. Malaria Journal (2022)
Journal (Open Access)
16) R. M. de Jong, L. Meerstein-Kessel, D. F. Da, S. Nsango, J. D. Challenger, M. van de Vegte-Bolmer, G. van Gemert, E. Duarte, N. Teyssier, R. W. Sauerwein, T. S. Churcher, R. K. Dabire, I. Morlais, E. Locke, M. A. Huynen, T. Bousema and M. M. Jore: Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoes. NPJ Vaccines (2021)
Journal (Open Access)
15) J. D. Challenger, D. Olivera Mesa, D. F. Da, R. S. Yerbanga, T. Lefèvre, A. Cohuet and T. S. Churcher: Predicting the public health impact of a malaria transmission-blocking vaccine. Nature Communications (2021)
Journal (Open Access)
14) R. Mumtaz, L. C. Okell and J. D. Challenger: Asymptomatic recrudescence after artemether–lumefantrine treatment for uncomplicated falciparum malaria: a systematic review and meta-analysis. Malaria Journal (2020)
Journal (Open Access) Preprint link
13) A. Mousa, A. Al-Taiar, N. M. Anstey, C. Badaut, B. E. Barber, Q. Bassat, J. D. Challenger, A. J. Cunnington, D. Datta, C. Drakeley, A. C. Ghani, V.R. Gordeuk, M. J. Grigg, P. Hugo, C. C. John, A. Mayor, F. Migot-Nabias, R. O. Opoka, G. Pasvol, C. Rees, H. Reyburn, E. M. Riley, B. N. Shah, A. Sitoe, C. J. Sutherland, P. E. Thuma, S. A. Unger, F. Viwami, M. Walther, C. J. M. Whitty, T. William, and L. C. Okell: The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis. Plos Medicine (2020)
Journal (Open Access)
12) E. Sherrard-Smith, A. B. Hogan, A. Hamlet, O. J. Watson, C. Whittaker, P. Winskill, F. Ali, A. B. Mohammad, P. Uhomoibhi, I. Maikore, N. Ogbulafor, J. Nikau, M. D. Kont, J. D. Challenger, R. Verity, B. Lambert, M. Cairns, B. Rao, M. Baguelin, L. K. Whittles, J. A. Lees, S. Bhatia, E. S. Knock, L. C. Okell, H. C. Slater, A. C. Ghani, P. G. T. Walker, O. O. Okoko, T. S. Churcher: The potential public health consequences of COVID-19 on malaria in Africa. Nature Medicine (2020)
Journal (Open Access)
11). J. D. Challenger, B. P. Goncalves, J. Bradley, K. Bruxvoort, A. B. Tiono, C. Drakeley, T. Bousema, A. C. Ghani and L. C. Okell: How delayed treatment and non-adherent treatment contribute to onward transmission of malaria: a modelling study. BMJ Global Health 4, e001856 (2019).
Journal (Open Access)
10) J. D. Challenger, K. Bruxvoort, A. C. Ghani and L. C. Okell: Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling. Nature Communications 8, 1373 (2017).
Journal (Open Access)
9) C. Parra-Rojas, J. D. Challenger, D. Fanelli and A. J. McKane: Suppressing escape events in maps of the unit interval with demographic noise. Physical Review E 94 052133 (2016).
8) J. D. Challenger, R. Burioni and D. Fanelli: Turing-like instabilities from a limit cycle. Physical Review E 92, 022818 (2015).
7) C. Parra-Rojas, J. D. Challenger, D. Fanelli and A. J. McKane: Intrinsic noise and two-dimensional maps: quasicycles, quasiperiodicity and chaos. Physical Review E 90, 032035 (2014).
6) M. Asllani, J. D. Challenger, F. S. Pavone, L. Sacconi and D. Fanelli: The theory of pattern formation on directed networks. Nature Communications 5, 4517 (2014).
Read the university press release for this article here (in italian)
5) J. D. Challenger, D Fanelli and A. J. McKane: The theory of individual based discrete-time processes. Journal of Statistical Physics 156, 131-155 (2014).
4) J. D. Challenger, D Fanelli and A. J. McKane: Intrinsic noise and discrete-time processes. Physical Review E Rapid Communication 88 040102(R) (2013).
3) J. D. Challenger and A. J. McKane: Synchronization of stochastic oscillators in biochemical systems. Physical Review E 88 012107 (2013).
2) J. D. Challenger, J. Pahle and A. J. McKane: Multi-Compartment linear noise approximation. Journal of Statistical Mechanics: Theory and Experiment P11010 (2012).
1) J. Pahle, J. D. Challenger, P. Mendes and A. J. McKane: Biochemical fluctuations, optimisation and the linear noise approximation. BMC Systems Biology 6:86 (2012).
Journal (Open Access)