About the Center

The Johns Hopkins Biomolecular NMR Center is a 3,600 square foot facility located on the Homewood Campus. Our aim is to provide resources for research, education and training for structural, mechanistic and functional studies of biological systems using state of the art Nuclear Magnetic Resonance (NMR) spectroscopic techniques. Research areas include, but are not restricted to, three-dimensional structure determination of proteins and nucleic acids, biomolecular interaction and dynamics, and the development of NMR methodology to advance the scope of applications.

The Center became operational in 2003, one of its primary objectives being to foster collaborative efforts among multiple departments and disciplines and create a vibrant Hopkins-wide NMR community. Emphasis was laid on facilitating the use of NMR spectroscopy by non-specialist laboratories in addressing relevant aspects of their research. This was achieved by providing active consultation and assistance – spanning both the Homewood, School of Medicine and Public Health campuses – and initiating extensive educational programs for researchers from these groups.

The NMR Center has a dual mission of research and training. It provides a variety of hands-on programs for students and researchers. Students also play an active role in the day-to-day maintenance and operation of the Center. Education and training activities are provided at various levels, ranging from one on one, hands on interaction, to structured courses for credit, available to undergraduate (since 2015) and graduate students (since 2017).

In an effort to expand our horizons, we are actively encouraging research groups outside of Hopkins to avail of our resources. Currently, we provide consultation and services to two external user groups, and this number is likely to increase in the future.

In 2019, the Krieger School of Arts and Sciences approved and fully financed a large scale upgrade to the facility resources, in the form of brand new, state of the art 600 MHz and 800 MHz instruments to completely replace two of the oldest spectrometers, which had outlived their utility. These systems were delivered in December 2019, and installation began in mid January, 2020. After a Covid-19 induced hiatus, installation was resumed, and completed in mid June, 2020. These instruments are now "open for business" to serve the entire Hopkins community.