About us

PI: Jakub Famulski, PhD

I was trained as a molecular cell biologist during my PhD, with a major focus on live cell imaging during cellular division. My postdoctoral training involved analysis of granule neuron progenitor differentiation and migration during cerebellar development. Currently, I am applying the zebrafish model system to study and model human ocular disease as well as analyze retinal morphogenesis. In particular I focus on colobomata, anterior segment dysgenesis and cone-rod dystrophy. In the lab we apply cutting edge confocal microscopy, transcriptomics and genome editing techniques to better understand these disorders.

Laboratory

The lab is located in the TH Morgan Building in the heart of the UK campus. It is equipped with a  Nikon C2+ confocal system adapted specifically for long term zebrafish embryo imaging. We also have access to the Z.1 light sheet microscope for high resolution 3D live imaging. The main lab is equipped with all standard molecular biology equipment including a Epoch nano spec, HRM rtPCR system, PCR machines, gel doc system and Nikon stereo microscopes. Our fish facility is located across the street and houses numerous mutant, transgenic and model zebrafish lines. With plenty of space and natural light, the laboratory  is inviting, efficient and professional.