Selected Publications

for a full publication list, please see my CV or: Google Scholar Page

2018

Sinnott JA, Brumberg K, Wilson KM, Ebot EM, Giovannucci EL, Mucci LA, Rider JR. Differential gene expression in prostate tissue according to ejaculation frequency. Eur Urol. 2018 Nov; 74(5): 545-548. doi: 10.1016/j.eururo.2018.05.006. Epub 2018 May 18. [PDF] [Appendix]

Sinnott JA, Cai F, Yu S, Hejblum BP, Hong C, Kohane IS, Liao KP. PheProb: probabilistic phenotyping using diagnosis codes to improve power for genetic association studies. J Am Med Inform Assoc. 2018 Oct; 25(10): 1359-1365. doi: 10.1093/jamia/ocy056. Epub 2018 May 17. [PDF] [Appendix] [software]

Sinnott JA, Cai T. Pathway aggregation for survival prediction via multiple kernel learning. Stat Med. 2018 Jul; 37(16): 2501-2515. doi: 0.1002/sim.7681. Epub 2018 Apr 17. [PDF] [Appendix] [software]

Neykov M, Hejblum BP, Sinnott JA. Kernel machine score test for pathway analysis in the presence of semi-competing risks. Stat Methods Med Res. 2018 Apr;27(4):1099-1114. doi: 10.1177/0962280216653427. Epub 2016 Jun 2. [PDF] [software]

2017

Sinnott JA, Peisch SF, Tyekucheva S, Gerke T, Lis R, Rider JR, Fiorentino M, Stampfer MJ, Mucci LA, Loda M, Penney KL. Prognostic Utility of a New mRNA Expression Signature of Gleason Score. Clin Cancer Res. 2017 Jan 1;23(1):81-87. doi: 10.1158/1078-0432.CCR-16-1245. Epub 2016 Sep 23. [link]

2016

Sinnott JA, Cai T. Inference for survival prediction under the regularized Cox model. Biostatistics. 2016 Oct;17(4):692-707. doi: 10.1093/biostatistics/kxw016. Epub 2016 Apr 22. [link] [contact for software]

Lu D*, Sinnott JA*, Valdimarsdóttir U, Fang F, Gerke T, Tyekucheva S, Fiorentino M, Lambe M, Sesso HD, Sweeney CJ, Wilson KM, Giovannucci EL, Loda M, Mucci LA, Fall K. Stress-Related Signaling Pathways in Lethal and Nonlethal Prostate Cancer. Clin Cancer Res. 2016 Feb 1;22(3):765-72. doi: 10.1158/1078-0432.CCR-15-0101. Epub 2015 Oct 21. (*co-first-authors) [link]

2015

Sinnott JA*, Rider JR*, Carlsson J, Gerke T, Tyekucheva S, Penney KL, Sesso HD, Loda M, Fall K, Stampfer MJ, Mucci LA, Pawitan Y, Andersson SO, Andrén O. Molecular differences in transition zone and peripheral zone prostate tumors. Carcinogenesis. 2015 Jun;36(6):632-8. doi: 10.1093/carcin/bgv051. Epub 2015 Apr 13. (*co-first-authors) [link]

Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T. Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Hum Genet. 2014 Nov;133(11):1369-82. doi: 10.1007/s00439-014-1466-9. Epub 2014 Jul 26. [link] [contact for software]

2013

Sinnott JA, Cai T. Omnibus risk assessment via accelerated failure time kernel machine modeling. Biometrics. 2013 Dec;69(4):861-73. doi: 10.1111/biom.12098. Epub 2013 Nov 6. [link] [software]

2012

Sinnott JA and Kraft P. Artifact due to differential error when cases and controls are imputed from different platforms. Human Genetics, 131(1):111–119, 2012. [link]

2011

Penney KL*, Sinnott JA*, Fall K, Pawitan Y, Hoshida Y, Kraft P, Stark JR, Fiorentino M, Perner S, Finn S, Calza S, Flavin R, Freedman ML, Setlur S, Sesso HD, Andersson SO, Martin N, Kantoff PW, Johansson JE, Adami HO, Rubin MA, Loda M, Golub TR, Andrén O, Stampfer MJ, and Mucci LA. mRNA expression signature of Gleason grade predicts lethal prostate cancer. Journal of Clinical Oncology, 29(17):2391–2396, 2011. (*co-first-authors) [link]