- 1969 - Marsha W. Timmerman graduates with B.S. in Zoology from Michigan State University
- 1971
- Marsha W. Timmerman graduates with M.S. in Zoology from Rutgers University
- Marsha W. Timmerman becomes a Researcher at Air Products and Chemicals, Inc.
- 1978 - Nancy L. Jones graduates with B.S. in Chemistry from University of Rochester
- 1982 - Nancy L. Jones acquires Postdoctoral position at University of California, Los Angeles
- 1983 - Nancy L. Jones graduates with Ph.D. in Inorganic Chemistry from Northwestern University
- 1984 - Nancy L. Jones acquires Postdoctoral position at University of Pennsylvania
- 1985
- Nancy L. Jones becomes Lecturer in Department of Chemistry at Bryn Mawr College
- Marsha W. Timmerman becomes Founding Scientist and Research Director of Enzymatics, Inc.
- 1986 - Nancy L. Jones joins Department of Chemistry and Biochemistry faculty at La Salle University
- 1988 - William L. Weaver graduates with B.S. in Chemistry and Physics from Slippery Rock University of Pennsylvania
- 1991
- Marsha W. Timmerman is awarded U.S. Patent 5,032,506
- Marsha W. Timmerman is awarded U.S. Patent 5,036,000
- 1992
- Marsha W. Timmerman is awarded U.S. Patent 5,112,741
- Marsha W. Timmerman is awarded U.S. Patent 5,126,247
- William L. Weaver graduates with Ph.D. in Analytical Chemistry from The Ohio State University
- William L. Weaver acquires Postdoctoral position at The Ohio State University
- 1993 - William L. Weaver becomes a Research Chemist at Systems Research Laboratories, Inc.
- 1994 - Marsha W. Timmerman becomes Director of Histochemistry at ImmunaCare, Corporation
- 1995
- Nancy L. Jones becomes Chair of Department of Chemistry and Biochemistry at La Salle University
- Marsha W. Timmerman becomes Co-founder and President of JWT, Inc.
- 1996 - William L. Weaver becomes an Analytical Chemist at Innovative Scientific Solutions, Inc.
- 1999
- Nancy L. Jones becomes ISBT Program Director at La Salle University
- Marsha W. Timmerman joins ISBT Program faculty at La Salle University
- William L. Weaver is awarded U.S. Patent 5,919,710
- William L. Weaver joins ISBT Program faculty at La Salle University
- August 2000
- ISBT Program accepts first incoming class of students
- ISBT Program establishes Electronics/Materials Laboratory in Holroyd 129
- ISBT101 is offered for the first time
- ISBT111 is offered for the first time
- January 2001
- ISBT102 is offered for the first time
- ISBT112 is offered for the first time
- March 2001 - ISBT Program receives $60,000 Agilent 1100 Series HPLC System as a grant from Agilent Technologies
- August 2001
- ISBT201 is offered for the first time
- ISBT211 is offered for the first time
- ISBT370 is offered
- January 2002
- ISBT202 is offered for the first time
- ISBT212 is offered for the first time
- ISBT Program receives $111,537 grant from the National Science Foundation
Incorporation of Problem-Based Learning into Two Courses - Technology Foundations II - Materials and Bioprocessing - in the Integrated Science, Business and Technology Program
- August 2002
- ISBT Program establishes Tissue Culture Laboratory in Holroyd Science Center
- Marsha W. Timmerman becomes faculty advisor for La Salle SIFE team
- ISBT374 is offered for the first time
- January 2003
- ISBT375 is offered for the first time
- March 2003 - SIFE Regional Championship won by La Salle SIFE team
- May 2003 - First Graduating B.S. in ISBT Class
- June 2003 - ISBT Program receives $66,417 grant from the National Science Foundation
Implementation of a Virtual Control Room in the Integrated Science, Business and Technology Program
- August 2003
- ISBT374 is offered for the second time
- ISBT474 is offered for the first time
- ISBT Program assumes stewardship of Holroyd 101 Computer Laboratory
- October 2003 - ISBT IKM Intelligent Systems students win National Instruments LabVIEW Checkers Coding Challenge
- January 2004
- ISBT375 is offered for the second time
- ISBT477 is offered for the first time
- March 2004 - SIFE Regional Championship won by La Salle SIFE team
- May 2004 - Second Graduating B.S. in ISBT Class
- June 2004
- ISBT Program converts Holroyd 16 into the Virtual Control Room
- ISBT Program renovates Holroyd 218 laboratory
- August 2004
- ISBT374 is offered for the third time
- ISBT474 is offered for the second time
- January 2005
- ISBT375 is offered for the third time
- ISBT477 is offered for the second time
- March 2005 - SIFE Regional Championship won by La Salle SIFE team
- May 2005 - Third Graduating B.S. in ISBT Class
- August 2005
- ISBT311 is established from ISBT374
- ISBT411 is established from ISBT474
- January 2006
- ISBT312 is established from ISBT375
- ISBT412 is established from ISBT477
- March 2006
- ISBTwiki is placed on internal servers
- SIFE Regional Championship won by La Salle SIFE team
- April 2006
- ISBTwiki is placed on external La Salle test server
- May 2006
- June 2006
- ISBT Page on Wikipedia is deleted by consensus of Wikipedians
- August 2006
- LEGO Mindstorms NXT robots are incorporated into ISBT411 curriculum.
- September 2006
- Deputy Commerce Secretary, Dr. David A. Sampson, addresses faculty and students on the importance of interdisciplinary programs such as ISBT to America's future and global competitiveness
- March 2007
- SIFE Regional Championship won by La Salle SIFE team
- April 2007
- United Devices completed its distributed computing project: Grid.org. Since joining the project in 2001, ISBT computers donated a total of 76 years, 323 days, 13h, 8 min, and 51 seconds of computational time to the project that included the phases:
- (2001) Cancer Research Project, with Intel
- (2002) Anthrax Project, with Intel and Microsoft
- (2004) Smallpox Research Grid Project, with IBM
- (2005) Human Proteome Folding Project, with IBM
- May 2007
- May 2008
- May 2009
- August 2009
- ISBT Department relocates into renovated Holroyd Hall
- ISBT IKM Concentration moves into new Virtual Control Room Laboratory in H-163
- May 2010
- Summer 2010
- ISBT Department evolves curriculum into "ISBT2.0"
- ISBTwiki moves from external La Salle test server to Google Sites
- ISBT Online - Massive Multiplayer Online Community (MMOC) virtual meeting and collaboration space for ISBT program
- ISBT Marketplace - internal economy among ISBT concentrations of BIO, IKM and ENR for collaborative projects and services