Publications

LAB PUBLICATIONS

Sharma, S., Bose, A., Biswas, S., Sen, S., & Roy, I. (2025). Cyperus rotundus mediated green synthesis of silver nanoparticles for antibacterial wound dressing applications. Scientific Reports, 15(1), 1-15.

Jain, S., Das, D., Mukherjee, A., & Roy, I. (2025). Inhibition of PolyGA Dipeptide Repeat Protein Aggregation by Nucleic Acid Aptamers in C9 Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Models. Molecular Neurobiology, 1-16.

Kaur, J., & Roy, I. (2025). Pharmacological Regulation of Heat Shock Response via Aptamer–Antidote Couple. ACS Chemical Neuroscience.

Vaidya, B., Biswas, S., Roy, I., & Sharma, S. S. (2025). HC070, a Transient Receptor Potential Canonical 5 (TRPC5) Channels Inhibitor Ameliorated α‐synuclein Preformed Fibrils‐Induced Parkinson's Disease: A Neurobehavioural and Mechanistic Study. Journal of Biochemical and Molecular Toxicology, 39(3), e70207.

Mukherjee, A., Biswas, S., & Roy, I. (2025). Exploring immunotherapeutic strategies for neurodegenerative diseases: a focus on Huntington’s disease and Prion diseases. Acta Pharmacologica Sinica, 1-28.

Mohan, A., & Roy, I. (2025). Exploring the Diagnostic Landscape: Portable Aptasensors in Point-of-care Testing. Analytical Biochemistry, 115788.

Kaur, J., Jain, R., Roychowdhury, S., Roy, R., Chattopadhyay, K., & Roy, I. (2025). Influence of Magnesium Ions and Crowding Agents on Structure and Stability of RNA Aptamers. Biochemistry.

Mohan, A., Puppala, V., & Roy, I. (2024). Protein Folding Pathways in the Presence of Osmolytes. In Cellular Osmolytes: From Chaperoning Protein Folding to Clinical Perspectives (pp. 1-16). Singapore: Springer Nature Singapore.

Quamar, M. F., Thakur, B., Sharma, A., Kumar, K., Tiwari, P., Tiwari, A., ... & Trivedi, A. (2024). Multiproxy studies on the spatially distinct surface samples to reconstruct palaeoecology and palaeoclimate from the Core Monsoon Zone of India. Journal of the Palaeontological Society of India, 69(1), 21-36.

Vaidya, B., Gupta, P., Biswas, S., Laha, J. K., Roy, I., & Sharma, S. S. (2024). Effect of clemizole on alpha-synuclein-preformed fibrils-Induced Parkinson’s disease pathology: a pharmacological investigation. NeuroMolecular Medicine, 26(1), 19.

Mukherjee, A., Biswas, S., & Roy, I. (2024). Immunotherapy: An emerging treatment option for neurodegenerative diseases. Drug Discovery Today, 103974.

BEHERA, R., ROY, I., RAHMAN, M., & MANDAL, A. (2024). Climate Resilience Livestock Production in Coastal Ecosystem of India. Journal of the Indian Society of Coastal Agricultural Research, 42(2).

Vaidya, B., Gupta, P., Laha, J. K., Roy, I., & Sharma, S. S. (2023). Amelioration of Parkinson's disease by pharmacological inhibition and knockdown of redox-sensitive TRPC5 channels: focus on mitochondrial health.LifeSciences,328,121871.

Das, E., & Roy, I. (2023). Tweaking Ire1 to Unlock Autophagy in Yeast. Autophagy Reports, 2(1). 

Thapa, A., Roy, I. D., Jayan, B., Ray, S., Kumar, A. N., & Antil, A. (2023). Volumetric analysis of pharyngeal airway dimensions and hyoid bone position following orthognathic surgery in skeletal class III patients: a cross sectional cephalometric study. International Journal of Otorhinolaryngology and Head and Neck Surgery, 9(12), 921.

Prasad, S., & Roy, I. (2023). Innovation in stabilization of biopharmaceuticals. In Recent Advances in Pharmaceutical Innovation and Research (pp. 3-40). Singapore: Springer Nature Singapore.

Puppala, V., Prasad, S., & Roy, I. (2023). Combinatorial Chemistry and High Throughput Screening Methods. In Some Key Topics in Chemistry and Biochemistry for Biotechnologists (pp. 44-63). CRC Press.

Puppala, V., Prasad, S., & Roy, I. (2023). 3 Chapter Combinatorial Chemistry and High. Some Key Topics in Chemistry and Biochemistry for Biotechnologists, 44.

Datana, S., Agarwal, S. S., & Roy, I. D. (2023). Bond failures of orthodontic attachments during orthognathic surgery: A retrospective study.

Jain, S., & Roy, I. (2023). Aptamer reduces aggregation of mutant huntingtin and rescues proteostasis network in non-neuronal and neuronal cells. ACS Chemical Neuroscience, 14(12), 2385-2395.

Das, E., Sahu, K. K., & Roy, I. (2023). The functional role of Ire1 in regulating autophagy and proteasomal degradation under prolonged proteotoxic stress. The FEBS Journal, 290(12), 3270-3289.

Parui, A., Biswas, S., & Roy, I. (2023). Meclofenoxate Inhibits Aggregation of Alpha-synuclein in vitro. Protein and peptide letters, 30(5), 361-366.

Dass, B., Rao, M. S., Roy, I., Kumar, S., & Sen, S. (2023). Integrated Water Security Planning and Springshed Management using High-Frequency Hydro-Meteorological Observations, Stable Isotopes, and Water Chemistry-Pilot Application in the Lesser Indian Himalayas. Authorea Preprints.

ROY, I., RAHMAN, M., BEHERA, R., KARUNAKARAN, M., & MANDAL, A. (2023). Garole-A Promising Sheep Breed in Coastal West Bengal. Journal of the Indian Society of Coastal Agricultural Research, 41(1), 64-70.

Banari, A. S., Datana, S., Agarwal, S. S., Chopra, S. S., & Roy, I. D. (2023). Comparison of upper airway post oral appliance therapy in patients with obstructive sleep apnea using 3 different modalities (lateral cephalogram, acoustic pharyngometry and CBCT)-A prospective clinical study. Journal of Contemporary Orthodontics [Internet], 7(3), 219-26.

Roy, I., & Gupta, M. N. (2023). White & grey biotechnologies for shaping a sustainable future. RSC Sustainability, 1(7), 1722-1736.

Tomar, A., Uysal-Onganer, P., Basnett, P., Pati, U., & Roy, I. (2022). 3D disease modelling of hard and soft cancer using PHA-based scaffolds. Cancers, 14(14), 3549.

Panuganti, V., & Roy, I. (2022). Oligomers, fibrils and aggregates formed by alpha-synuclein: role of solution conditions. Journal of Biomolecular Structure and Dynamics, 40(10), 4389-4398.

Vaidya, B., Roy, I., & Sharma, S. S. (2022). Neuroprotective potential of HC070, a potent TRPC5 channel inhibitor in Parkinson′ s disease models: a behavioral and mechanistic study. ACS chemical neuroscience, 13(18), 2728-2742.

Pallapati, A. R., Prasad, S., & Roy, I. (2022). Glycerol 3-phosphate dehydrogenase regulates heat shock response in Saccharomyces cerevisiae. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1869(5), 119238.

Singh, K., Sethi, R., Das, E., & Roy, I. (2022). The role of the glycerol transporter channel Fps1p in cellular proteostasis during enhanced proteotoxic stress. Applied Microbiology and Biotechnology, 106(18), 6169-6180.

Agarwal, S. S., Datana, S., Roy, I. D., & Andhare, P. (2022). Effectiveness of titratable oral appliance in management of moderate to severe obstructive sleep apnea—a prospective clinical study with acoustic pharyngometry. Indian Journal of Otolaryngology and Head & Neck Surgery, 1-7.

Andhare, P., Datana, S., Agarwal, S. S., Chopra, S. S., & Roy, I. D. (2022). Upper Airway Post-planned Positioning of Maxillary Anterior Teeth: An Acoustic Pharyngometric Study. Indian Journal of Sleep Medicine, 17(1), 5-9.

Luong, A. D., Roy, I., Malhotra, B. D., & Luong, J. H. (2021). Analytical and biosensing platforms for insulin: A review. Sensors and Actuators Reports, 3, 100028.

Jain, S., Kaur, J., Prasad, S., & Roy, I. (2021). Nucleic acid therapeutics: a focus on the development of aptamers. Expert Opinion on Drug Discovery, 16(3), 255-274.

Biswas, S., Bhadra, A., Lakhera, S., Soni, M., Panuganti, V., Jain, S., & Roy, I. (2021). Molecular crowding accelerates aggregation of α-synuclein by altering its folding pathway. European Biophysics Journal, 50(1), 59-67.

Gupta, M. N., & Roy, I. (2021). Drugs, host proteins and viral proteins: How their promiscuities shape antiviral design. Biological Reviews, 96(1), 205-222.

Gupta, M. N., & Roy, I. (Eds.). (2021). Three phase partitioning: applications in separation and purification of biological molecules and natural products. Elsevier.

Das, E., Prasad, S., & Roy, I. (2021). Saccharomyces cerevisiae Fpr1 functions as a chaperone to inhibit protein aggregation. International Journal of Biological Macromolecules, 191, 40-50.

Pallapati, A. R., Sirigiri, S. D., Jain, S., Ratnala, V., & Roy, I. (2021). Lysine245 plays a crucial role in stability and function of glycerol 3‐phosphate dehydrogenase (Gpd1) in Saccharomyces cerevisiae. Journal of Cellular Biochemistry, 122(11), 1726-1736.

Chauhan, D., Roy, I. D., Viswamnara, M., Thakur, A., & Athwale, R. (2021). Rehabilitation of Auricular Defect with Implant-Retained Auricular Prosthesis-A Case Report. Annals of Maxillofacial Surgery, 11(1), 164-168.

Datana, S., Agarwal, S. S., & Roy, I. D. (2021). Broken orthodontic appliance during orthognathic surgery: Preventable adverse outcome. Medical Journal, Armed Forces India, 79(Suppl 1), S387.

Roy, I., & Gupta, M. N. (2021). Macro-(affinity ligand) facilitated three phase partitioning Converting TPP into an affinity based process. In Three Phase Partitioning (pp. 175-196). Elsevier.

Prasad, S., & Roy, I. (2021). What does Our Experience of COVID-19 Teach Us?. Vantage: Journal of Thematic Analysis, 2(1), 22-41.

Gupta, M. N., & Roy, I. (2021). Applications of three phase partitioning and macro-(affinity ligand) facilitated three phase partitioning in protein refolding. In Three Phase Partitioning (pp. 197-222). Elsevier.

Jain, S., Panuganti, V., Jha, S., and Roy, I. (2020) Harmine Acts as an Indirect Inhibitor of Intracellular Protein Aggregation. ACS Omega. 5, 5620–5628. 

Jain, S., Kaur, J., Prasad, S., and Roy, I. (2020) Nucleic acid therapeutics: A focus on the development of aptamers. Expert Opin. Drug Discov.  DOI: 10.1080/17460441.2021.1829587 

Panuganti, V., and Roy, I. (2020) Oligomers, fibrils and aggregates formed by alpha-synuclein: role 

of solution conditions.  J. Biomol. Struct. Dyn. DOI: 10.1080/07391102.2020.1856721.

Gupta, M.N. and Roy, I. (2020), Drugs, host proteins and viral proteins: how their promiscuities shape antiviral design. Biol Rev. https://doi.org/10.1111/brv.12652 

Sethi, R., and Roy, I. (2020) Stabilization of elongated polyglutamine tracts by a helical peptide 

derived from N‐terminal huntingtin.  IUBMB Life. 72, 1528– 1536. 

Gupta, M. N. and Roy, I. (2020) How corona formation impacts nano-materials as drug carriers? Mol. Pharm. DOI: 10.1021/acs.molpharmaceut.9b01111. 

Singh, V., Patel, K. A., Sharma, R. K., Patil, P. R., Joshi, A. S., Parihar, R., Athilingam, T., Sinha, N., Ganesh, S., Sinha, P., Roy, I., and Thakur, A. K. (2019) Discovery of Arginine Ethyl Ester as Polyglutamine Aggregation Inhibitor: Conformational Transitioning of Huntingtin N-Terminus Augments Aggregation Suppression. ACS Chem. Neurosci. 10, 3969-3985.

Singh, K., and Roy, I. (2019) Nucleic Acid Therapeutics in Huntington’s Disease. Recent Patents on Biotechnology 13, 187-206.

Patel, K. A., Chaudhary, R. K., and Roy, I. (2018) RNA Aptamers Rescue Mitochondrial Dysfunction in a Yeast Model of Huntington’s Disease. Mol. Ther. Nucleic. Acids 12, 45-56.

Patel, K. A., Kolluri, T., Jain, S., and Roy, I. (2018) Designing aptamers which respond to intracellular oxidative stress and inhibit aggregation of mutant huntingtin. Free Radic. Biol. Med. 120, 311-316.

Sethi, R., Iyer, S. S., Das, E., and Roy, I. (2018) Discrete roles of trehalose and Hsp104 in inhibition of protein aggregation in yeast cells. FEMS Yeast Research 18.

Sethi, R., Tripathi, N., Pallapati, A. R., Gaikar, A., Bharatam, P. V., and Roy, I. (2018) Does N‐terminal huntingtin function as a ‘holdase’ for inhibiting cellular protein aggregation? The FEBS Journal 285, 1791-1811.

Prasad, S., and Roy, I. (2017) Converting Enzymes into Tools of Industrial Importance. Recent Patents on Biotechnology 12.

Prasad, S. and Roy, I. (2017) Obtaining a high activity subtilisin preparation by controlled thermal stress in n-octane. Anal. Biochem. 534, 86-90.

Prasad, S. and Roy, I. (2017) A sensitive, rapid and specific technique for the detection of collagenase using zymography. In: Methods in Molecular Biology    (Eds. Wilkesman, J. and Kurz, L.), Vol. 1626, Humana Press, New York, pp. 115-121.

Pallapati, A.R.*, Das, E.* and Roy, I. (2017) Crosstalk between osmolytes and cellular chaperones: examples in Saccharomyces cerevisiae. In: Cellular osmolytes (Eds. Singh, L.R. and Dar, T.A.), Springer Nature Singapore Pte Ltd., Singapore, pp. 55-75. * equal contribution

Kardani, J., Sethi, R. and Roy, I. (2017) Nicotine slows down oligomerisation of alpha-synuclein and ameliorates cytotoxicity in a yeast model of Parkinson's  disease. Biochim. Biophys. Acta – Mol. Basis Dis. 1863, 1454-1463

Roy, I., Mukherjee, J. and Gupta, M. N. (2017) Cross-linked enzyme aggregates for applications in aqueous and nonaqueous media. In: Methods in Molecular Biology (Ed. Minteer, S. D.), 2nd edition, Vol. 1504, Springer Sciences, New York, pp. 109-123.

Patel, K. P., Sethi, R., Dhara, A. R. and Roy, I. (2017) Challenges with osmolytes as inhibitors of protein aggregation: Can nucleic acid aptamers provide an answer? Int. J. Biol. Macromol. 100, 75-88.

Prasad, S., Negi, V. S., Laha, J. K. and Roy, I. (2016) Differential effect of a chemical denaturant on activity and stability of a serine protease in nonaqueous media. J. Mol. Catal. B Enzym. 134, 32-36.

Modh HB,  Bhadra AK, Patel KA, Chaudhary RK , Jain NK , Roy I. (2016) Specific detection of tetanus toxoid using an aptamer-based matrix. J Biotechnol. 238:15-21.

Prasad S, Negi VS, Laha JK, Roy I. (2016) Differential effect of a chemical denaturant on activity and stability of a serine protease in nonaqueous media. J Mol Cat B: Enzymatic. 134:32-36.

Bhadra AK, Das E, Roy I. (2016) Protein aggregation activates erratic stress response in dietary restricted yeast cells. Sci Rep. 6:33433. doi: 10.1038/srep33433.

Sethi R, Patel V, Saleh AA, Roy I. (2016) Cellular toxicity of yeast prion protein Rnq 1 can be modulated by N-terminal wild type huntingtin. Arch Biochem Biophys. 590:82-89.

Patel KA, Sethi R, Dhara AR, Roy I. (2016) Challenges with osmolytes as inhibitors of protein aggregation: Can nucleic acid aptamers provide an answer? Int J Biol Macromol.doi: 10.1016/j.ijbiomac.2016.05.014.

Chaudhary RK, Patel KA, Patel MK, Joshi RH, Roy I. (2015) Inhibition of aggregation of mutant huntingtin by nucleic acid aptamers in vitro and in a yeast model of Huntington's disease. Mol Ther. 23(12):1912-26

Kardani J, Roy I. (2015) Understanding Caffeine's Role in Attenuating the Toxicity of α-Synuclein Aggregates: Implications for Risk of Parkinson's Disease. ACS Chem Neurosci. 6(9):1613-25.

Bhadra AK, Roy I. (2015) Gpd1 Regulates the Activity of Tcp-1 and Heat Shock Response in Yeast Cells: Effect on Aggregation of Mutant Huntingtin. Mol Neurobiol. 53(6):3900-13

Gade VR, Kardani J, Roy I. (2014) Effect of endogenous Hsp104 chaperone in yeast models of sporadic and familial Parkinson's disease. Int J Biochem Cell Biol. 55:87-92.

Saleh AA, Bhadra AK, Roy I. (2014) Activation of salt shock response leads to solubilisation of mutant huntingtin in Saccharomyces cerevisiae. Cell Stress Chaperones. 19(5):667-73.

Saleh AA, Gune US, Chaudhary RK, Turakhiya AP, Roy I. (2014) Roles of Hsp104 and trehalose in solubilisation of mutant huntingtin in heat shocked Saccharomyces cerevisiae cells. Biochim Biophys Acta. 1843(4):746-57.

Saleh AA, Bhadra AK, Roy I. (2014) Cytotoxicity of mutant huntingtin fragment in yeast can be modulated by the expression level of wild type huntingtin fragment. ACS Chem Neurosci. 5(3):205-15.

Jetani HC, Bhadra AK, Jain NK, Roy I. (2014) Nucleic acid aptamers stabilize proteins against different types of stress conditions. J Pharm Sci. 103(1):100-6.

Prasad SC and Roy I. (2013) Environmental factors and neurodegenerative diseases (CRIPS) ISSN 0972-589X. 9(3): 49-55

Chaudhary RK, Kardani J, Singh K, Banerjee R, Roy I. (2014) Deciphering the roles of trehalose and Hsp104 in the inhibition of aggregation of mutant huntingtin in a yeast model of Huntington's disease. Neuromolecular Med. 16(2):280-91.

Bhavsar RD, Prasad S, Roy I. (2013) Effect of osmolytes on the fibrillation of HypF-N. Biochimie. 95(11):2190-3.

Sutariya NM, Prasad S, Athavale DA, Bhavsar RD, Roy I. (2013) Correlation between Al(3+) -induced thermal stability and inhibition of fibrillation of N-terminal domain of the hydrogenase maturation factor. Biofactors. 39(6):597-607.

Singh K, Saleh AA, Bhadra AK, Roy I. (2013) Hsp104 as a key modulator of prion-mediated oxidative stress in Saccharomyces cerevisiae. Biochem J. 454(2):217-25.

Malik R, Roy I. (2013) Stabilization of bovine insulin against agitation-induced aggregation using RNA aptamers. Int J Pharm. 452(1-2):257-65.

Jain NK, Jetani HC, Roy I. (2013) Nucleic acid aptamers as stabilizers of proteins: the stability of tetanus toxoid. Pharm Res. 30(7):1871-82.

Vachharajani SN, Chaudhary RK, Prasad S, Roy I. (2012) Length of polyglutamine tract affects secondary and tertiary structures of huntingtin protein. Int J Biol Macromol. 51(5):920-5.

Malik R, Roy I. (2011) Making sense of therapeutics using antisense technology. Expert Opin Drug Discov. 6(5):507-26.

Deshmukh RS, Chaudhary RK, Roy I. (2012) Effect of pesticides on the aggregation of mutant huntingtin protein. Mol Neurobiol. 45(3):405-14.

Solanki VA, Jain NK, Roy I. (2012) Stabilization of tetanus toxoid formulation containing aluminium hydroxide adjuvant against agitation. Int J Pharm. 423(2):297-302.

Solanki VA, Jain NK, Roy I. (2011) Stabilization of tetanus toxoid formulation containing aluminium hydroxide adjuvant against freeze-thawing. Int J Pharm. 414(1-2):140-7.

Prasad S, Khadatare PB, Roy I. (2011) Effect of chemical chaperones in improving the solubility of recombinant proteins in Escherichia coli. Appl Environ Microbiol. 77(13):4603-9.

Malik R, Roy I. (2011) Probing the mechanism of insulin aggregation during agitation. Int J Pharm. 413(1-2):73-80.  

Makwana PK, Jethva PN, Roy I. (2011) Coumarin 6 and 1,6-diphenyl-1,3,5-hexatriene (DPH) as fluorescent probes to monitor protein aggregation. Analyst. 136(10):2161-7.

Jethva PN, Kardani JR, Roy I. (2011) Modulation of α-synuclein aggregation by dopamine in the presence of MPTP and its metabolite. FEBS J. 278(10):1688-98.

Jain NK, Roy I. (2011) Accelerated stability studies for moisture-induced aggregation of tetanus toxoid. Pharm Res. 28(3):626-39.

Jain NK, Roy I. Trehalose and protein stability. Curr Protoc Protein Sci. 2010; Chapter 4:Unit 4.9.

Prasad S, Roy I. (2010) Effect of disaccharides on the stabilization of bovine trypsin against detergent and autolysis. Biotechnol Prog. 26(3):627-35.

Jain NK, Roy I. (2009) Effect of trehalose on protein structure. Protein Sci. 18(1):24-36.

Prasad SC, Roy I. (2008) Nucleic acid based therapeutic molecules. Current Research and Information on Pharmaceutical Sciences (CRIPS) ISSN 0972-589X, 9(3): 49-55.

Malik R, Roy I. (2008) Design and development of antisense drugs. Expert Opin Drug Discov. 3(10):1189-207.

Jain NK, Roy I. (2008) Role of trehalose in moisture-induced aggregation of bovine serum albumin. Eur J Pharm Biopharm. 69(3):824-34.

Thanzami K, Roy I. (2008) A sensitive, rapid and specific technique for the detection of collagenase using zymography. Electrophoresis. 29(7):1585-8.

Kaur G, Roy I. (2008) Therapeutic applications of aptamers. Expert Opin Investig Drugs. 17(1):43-60.

OTHER PUBLICATIONS

Roy I, Mondal K, Gupta MN. (2014) Simultaneous purification and refolding of proteins by affinity precipitation and macro (affinity ligand)-facilitated three phase partitioning (MLFTPP). Methods Mol Biol.1129:111-123. 

Roy I, Mukherjee J, Gupta MN. (2013) High activity preparations of lipases and proteases for catalysis in low water containing organic solvents and ionic liquids. Methods Mol Biol. 1051:275-284. 

Gautam S, Mukherjee J, Roy I, Gupta MN. (2013) Emerging trends in designing short and efficient protein purification  protocols. Am. J. Biochem. Biotechnol. 8, 230-254.

Goyal MK, Roy I, Amin A, Banerjee UC, Bansal AK. (2010) Stabilization of lysozyme by benzyl alcohol: surface tension and thermodynamic parameters. J Pharm Sci. 99(10):4149-4161. 

Goyal MK, Roy I, Banerjee UC, Sharma VK, Bansal AK. (2009) Role of benzyl alcohol in the prevention of heat-induced aggregation and inactivation of hen egg white lysozyme. Eur J Pharm Biopharm. 71(2):367-76. 

Roy I, Mondal K, Gupta MN. (2007) Leveraging protein purification strategies in proteomics. J Chromatogr B Analyt Technol Biomed Life Sci. 849(1-2):32-42.

Roy I. Fighting protein misfolding diseases. (2007) Pharm. Technol. Eur. 19, 35-43.

Mondal K, Ramesh NG, Roy I, Gupta MN. (2006) Enhancing the synthetic utility of aldolase antibody 38C2. Bioorg. Med. Chem. Lett. 16, 807-810.

Roy I, Gupta MN. (2006) Immobilization of enzymes on smart polymers. In: Immobilization of enzymes and cells (ed. Guisan JM), 2nd edition, Humana Press, Totowa, USA, 87-96.

Roy  I, Gupta MN. (2006) Bioaffinity immobilization. In: Immobilization of enzymes and cells (ed. Guisan JM), 2nd edition, Humana Press, Totowa, USA, 107-116.

Roy  I,  Gupta MN. (2006) Use of immobilized biocatalysts in fluidized bed format. In: Immobilization of enzymes and cells (ed. Guisan JM), 2nd edition, Humana Press, Totowa, USA, 311-320.

Roy I, Mondal K, Sharma A, Gupta MN. (2005) Simultaneous refolding/purification of xylanase with a microwave treated smart polymer. Biochim. Biophys. Acta 1747, 179-187.

Roy I, Sardar M, Gupta MN. (2005) Crosslinked alginate-guar gum beads as fluidized bed affinity media for purification of jacalin.  Biochem. Eng. J. 23, 193-198.

Singh N, Jabeen T, Sharma S, Roy I, Gupta MN, Bilgrami S, Baxla AP, Dey S, Perbandt M, Betzel C, Singh TP. (2005) Detection of native peptides as potent inhibitors of enzymes: Crystal structure of the complex formed between   the treated bovine a-chymotrypsin and an autocatalytically produced octapeptide: Ala-Val-Pre-Gly-Ser-Trp-Pro-Trp at 2.2 Å resolution. FEBS J. 272, 562-572.

Gupta A, Roy I, Patel RK, Singh SP, Khare SK, Gupta MN. (2005) One-step purification and characterization of an alkaline protease from haloalkaliphilic Bacillus sp. J. Chromatogr. A 1075, 103-108.

Roy I, Sharma A, Gupta MN. (2005) Recovery of biological activity in reversibly inactivated proteins by three phase partitioning. Enzyme Microb. Technol. 37, 113-120.

Gupta A, Roy I, Khare SK, Gupta MN. (2005) Purification and characterization of a solvent stable protease from Pseudomonas aeruginosa PseA. J. Chromatogr. A 1069, 155-161.

Roy I, Gupta MN. (2005) Enhancing reaction rate for transesterification reaction catalyzed by Chromobacterium lipase. Enzyme Microb. Technol. 36, 896-899.

Gupta MN, Roy I. (2004) Enzymes in organic media: Forms, functions and applications. Eur. J. Biochem. 271, 2575-2583.

Roy I, Sharma A, Gupta MN. (2004) Obtaining higher transesterification rates with subtilisin Carlsberg in nonaqueous media. Bioorg. Med. Chem. Lett. 14, 887-889.

Roy I, Gupta, M. N. (2004) Preparation of highly active a-chymotrypsin for catalysis in organic media. Bioorg. Med. Chem. Lett. 14, 2191-2193.

Roy I, Sharma A, Gupta, M. N. (2004) Three phase partitioning for simultaneous renaturation and partial purification of Aspergillus niger xylanase. Biochim. Biophys. Acta 1698, 107-110.

Roy I, Gupta MN. (2004) Hydrolysis of starch by a mixture of glucoamylase and pullulanase entrapped individually in calcium alginate beads Enzyme Microb. Technol. 34, 26-32.

Sharma A, Roy I, Gupta MN. (2004) Affinity precipitation and macroligand facilitated three phase partitioning for refolding of urea-denatured pectinase. Biotechnol. Prog. 20, 1255-1258.

Roy I, Gupta MN. (2004) Freeze-drying of proteins: Some emerging concerns. Biotechnol. Appl. Biochem. 39, 165-177.

Roy I, Jain S, Teotia S, Gupta MN. (2004) Evaluation of microbeads of calcium-alginate as a fluidised bed medium for affinity chromatography of Aspergillus niger pectinase. Biotechnol. Prog. 20, 1490-1495.

Roy I, Gupta M N. (2004) Three phase partitioned a-chymotrypsin shows higher activity in water as well as organic solvents Biocatal. Biotransf. 22, 261-268.

Jain S, Roy I, Gupta MN. (2004) A smart bioconjugate of trypsin with alginate Artificial Cells Blood Subst. Biotechnol. 32, 343-355.

Roy I, Sharma S, Gupta MN. (2003) Smart biocatalysts: Design and application. Adv. Biochem. Eng. Biotechnol. 86, 159-189.

Roy I, Gupta A, Khare SK, Bisaria VS, Gupta MN. (2003) Immobilization of xylan-degrading enzymes from Melanocarpus albomyces IIS 68 on the smart polymer Eudragit L-100 Appl. Microb. Biotechnol.  61, 309-313.

Roy I, Gupta MN. (2003) Selectivity in affinity chromatography. In: Isolation and purification of proteins (eds. Mattiasson B, Kaul-Hatti R.) Marcel Dekker Inc., New York, 57-94.

Roy I, Rao MVS, Gupta MN. (2003) An integrated process for the purification of lysozyme, ovalbumin and ovomucoid from hen egg white Appl. Biochem. Biotechnol. 111, 56-64.

Sardar M, Roy I, Gupta MN. (2003) A smart bioconjugate of alginate and pectinase with unusual biological activity towards chitosan. Biotechnol. Prog.  19, 1654-1658.

Roy I, Gupta MN. (2003) Lactose hydrolysis by LactozymTM immobilized on cellulose beads in batch and fluidized bed modes Process Biochem. 39, 325-332.

Roy I, Sardar M, Gupta MN. (2003) Hydrolysis of chitin by PectinexTM. Enzyme Microb. Technol. 32, 582-588.

Roy I, Sardar M, Gupta MN. (2003) Evaluation of a smart bioconjugate of pectinase for chitin hydrolysis. Biochem. Eng. J. 16, 329-335.

Roy I, Gupta MN. (2003) k-Carrageenan as a new smart macroaffinity ligand for purification of pullulanase. J. Chromatogr. A 998, 103-108.

Roy I, Gupta MN. (2003) Use of pectinase immobilized on k-carrageenan for hydrolysis of polygalacturonic acid, chitosan and chitin Biocatal. Biotrans. 21, 297-304.

Roy I, Gupta MN. (2003) Non-thermal effects of microwave on protease-catalyzed esterification and transesterification. Tetrahedron 59, 5431-5436.

Safarikova M, Roy I, Gupta MN, Safarik I. (2003) Magnetic alginate microparticles for purification of a-amylases. J. Biotechnol. 105, 255-260.

Roy I, Mondal K, Gupta MN. (2003) Accelerating enzymatic hydrolysis of chitin by microwave pre-treatment Biotechnol. Prog. 19, 1648-1653.

Roy I, Gupta MN. (2003) Smart materials: emerging biochemical applications. Chem. Biol. 10, 1161-1171.

Mondal K, Roy I, Gupta MN. (2003) Enhancement of catalytic efficiencies of xylanase, pectinase and cellulase by microwave pretreatment of their substrates Biocatal. Biotrans. 22, 9-16.

Mondal K, Roy I, Gupta MN. (2003) k-Carrageenan as a Carrier in affinity precipitation of yeast alcohol dehydrogenase Protein Expr. Purif. 32, 151-160.

Roy I, Gupta MN. (2003) Applications of microwaves in biological sciences. Curr. Sci. 85, 1685-1693.

Roy I, Gupta MN. (2003) pH responsive polymer-assisted refolding of urea-denatured a-chymotrypsin. Protein Eng. 16, 1153-1157.

Roy I, Rao MVS, Gupta MN. (2003) Purification of lysozyme from other hen egg white proteins using metal affinity precipitation. Biotechnol. Appl. Biochem. 37, 9-14.

Roy I, Gupta MN. (2002) Three phase affinity partitioning of proteins. Anal. Biochem. 300, 11-14.

Gupta MN, Roy I. (2002) Affinity-based separation: An overview. In: Methods for affinity-based separation of proteins/enzymes (ed. Gupta, M. N.) Birkhauser Verlag, Basel, 1-15.

Roy I, Gupta MN. (2002) Macroaffinity ligands in bioseparation In: Methods for affinity-based separation of proteins/enzymes (ed. Gupta, M. N.) Birkhauser Verlag, Basel, 130-147.

Roy I, Gupta MN. (2002) Unexpected affinity of polysaccharides and its application in separation of enzymes on fluidized beds. Sep. Sci. Technol. 37, 1591-1610.

Roy I, Sharma S, Gupta MN. (2002) Separation of an isoenzyme of polyphenol oxidase from Duranta plumieri by expanded bed chromatography. Protein Expr. Purif.  24, 181-187.

Gupta MN, Jain S, Roy I. (2002) Immobilized metal affinity chromatography without chelating ligands - Purification of soybean trypsin inhibitor on zinc alginate beads Biotechnol. Prog. 18, 78-81.

Roy I, Gupta MN. (2002) Purification of a bacterial pullulanase on a fluidized bed of calcium alginate beads J. Chromatogr.  A 950, 131-137.

Roy I, Gupta MN. (2002) Applied Biocatalysis: An Overview. Ind. J. Biochem. Biophys. 39, 220-228.

Roy I, Gupta MN. (2002) Downstream processing of enzymes/proteins.  Proc. Ind. Natl. Sci. Acad. (B) B68, 175-204.

Gupta A, Roy I, Khare SK, Bisaria VS. Gupta MN. (2002) One-step purification of xylanase from Melanocarpus albomyces and ethylene glycol as a novel soluble additive for enhancing its thermal stability Biotechnol. Lett. 24, 2005-2009.

Singh RK, Gourinath S, Sharma S, Roy I, Gupta MN, Betzel C, Srinivasan A, Singh TP. (2001) Enhancement of enzyme activity through three phase partitioning: Crystal structure of a modified serine protease at 1.5 Å resolution. Protein Eng. 14, 307-313.

Sharma S, Roy I, Gupta MN. (2001) Separation of phospholipase D from peanut on a fluidized bed of crosslinked alginate beads. Biochem. Eng. J. 8, 235-239.

Roy I, Gupta MN. (2000) Current trends in affinity-based separation of proteins/enzymes. Curr. Sci. 78, 587-591.

Roy I, Sardar M, Gupta MN. (2000) Exploiting unusual affinity of usual polysaccharides for bioseparation of enzymes on fluidized beds Enzyme Microb. Technol. 27, 53-65.

Roy I, Gupta MN. (2000) Purification of alkaline phosphatase from chicken intestine by expanded bed affinity chromatography on dye-linked cellulose. Biotechnol. Appl. Biochem. 32, 81-87.

Sardar M, Roy I, Gupta MN. (2000) Simultaneous purification and immobilization of Aspergillus niger xylanase on the reversibly soluble polymer Eudragit L-100. Enzyme Microb. Technol. 27, 672-679.

Roy I, Sastry MSR, Johri BN, Gupta MN. (2000) Purification of an alpha amylase from Scytalidium thermophilum on a fluidized bed of alginate beads. Protein Expr. Purif. 20, 162-168.

Roy I, Gupta MN. (2000) Purification of a ‘double-headed’ inhibitor of alpha-amylase / Proteinase K from wheat germ by expanded bed chromatography. Bioseparation 9, 239-245.

Roy I, Pai A, Lali A, Gupta MN. (1999) Comparison of batch, packed bed and expanded bed purification of A. niger cellulase using cellulose beads Bioseparation 8, 317-326.

Tyagi R, Roy I, Agarwal R, Gupta MN. (1998) Carbodiimide coupling of enzymes to the reversibly soluble-insoluble polymer Eudragit S-100. Biotechnol. Appl. Biochem. 28, 201-206.

Roy I. (2007) Purification of monoclonal antibodies. Current Research and Information on Pharmaceutical Sciences (CRIPS) ISSN 0972-589X, 8(2), 22-26.

PATENT

Process for the isolation and purification of a glycoprotein avidin. USPTO 7,205,393 B2 dt. April 17, 2007. A23J1/08; C07K14/465; A23J1/00; C07K14/435; (IPC17): C07K14/47 (International) dt. April 1, 2004 A23J1/08; C07K14/465 (European).

BOOK EDITED

Bio-Nano-Geo Sciences. The Future Challenge (2009). Editors: Srivastava A, Roy I. Ane Books Pvt. Ltd., New Delhi, India. ISBN (13) 978-81-8052-180-5.