Publications

2024

Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease: Opportunities for therapy

Kelly, L., Brown, C., Michalik, D., ...Mazer, N., Carare, R.O.

Alzheimer's and Dementia, 2024, 20(2), pp. 1421–1435 

2023

CAA-ri and ARIA: Two Faces of the Same Coin?

Zedde, M., Pascarella, R., Piazza, F.

American Journal of Neuroradiology, 2023, 44(2), pp. E13–E14 


The Venular Side of Cerebral Amyloid Angiopathy: Proof of Concept of a Neglected Issue

Zedde, M., Grisendi, I., Assenza, F., ...Valzania, F., Pascarella, R.

Biomedicines, 2023, 11(10), 2663 


2022

Association of Microglial Activation With Spontaneous ARIA-E and CSF Levels of Anti-Aβ Autoantibodies

Fabrizio Piazza,  Silvia Paola Caminiti,  Marialuisa Zedde, Luca Presotto,  Jacopo C. DiFrancesco,  Rosario Pascarella, Alessia Giossi, Maria Sessa,  Loris Poli,  Gianpaolo Basso, Daniela Perani

Neurology, September 20, 2022; 99 (12) , DOI: https://doi.org/10.1212/WNL.0000000000200892


Author Response: Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study 

Piazza, F., Basso, G., Pascarella, R., Carare, R.O., Zedde, M.

Neurology, 2022, 99(16), pp. 729 


The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

Charidimou, A., Boulouis, G., Frosch, M.P., ...Werring, D.J., Greenberg, S.M.

The Lancet Neurology, 2022, 21(8), pp. 714–725



Large Collaborative Registries and Real-world Data to Manage Amyloid-Related Imaging Abnormalities

Piazza, F., Frölich, L., Padovani, A.

JAMA Neurology, 2022, 79(6), pp. 633–634


In silico exploration of amyloid-related imaging abnormalities in the gantenerumab open-label extension trials using a semi-mechanistic model

Aldea, R., Lott, D., Piazza, F., ...Klein, G., Lyons, M.

Alzheimer's and Dementia: Translational Research and Clinical Interventions, 2022, 8(1), e12306


2021

Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy–Related Inflammation: A Multicenter Prospective Longitudinal Cohort Study.

Laura Antolini, Jacopo C DiFrancesco, Marialuisa Zedde, Gianpaolo Basso, Andrea Arighi, Atsushi Shima, Annachiara Cagnin, Massimo Caulo, Roxana Carare, Andreas Charidimou, Mario Cirillo, Vincenzo Di Lazzaro, Carlo Ferrarese, Alessia Giossi, Domenico Inzitari, Michela Marcon, Roberto Marconi, Masafumi Ihara, Ricardo Nitrini, Berardino Orlandi, Alessandro Padovani, Rosario Pascarella, Francesco Perini, Giulia Perini, Maria Sessa, Elio Scarpini, Fabrizio Tagliavini, Raffaella Valenti, Juan Francisco Vázquez-Costa, Alberto Villarejo-Galende, Yuta Hagiwara, Nicole Ziliotto, Fabrizio Piazza.

Neurology. September 16, 2021, DOI: https://doi.org/10.1212/WNL.0000000000012778 


Hemostasis components in cerebral amyloid angiopathy and Alzheimer’s disease

Ziliotto, N., Bernardi, F., Piazza, F.

Neurological Sciences, 2021, 42(8), pp. 3177–3188


2020

Clearance of interstitial fluid (ISF) and CSF (CLIC) group—part of Vascular Professional Interest Area (PIA)

Cerebrovascular disease and the failure of elimination of Amyloid‐β from the brain and retina with age and Alzheimer's disease‐Opportunities for Therapy

Roxana O. Carare  Roxana Aldea  Nivedita Agarwal  Brian J. Bacskai  Ingo Bechman  Delphine Boche  Guojun Bu  Diederik Bulters  Alt Clemens  Scott E. Counts  Mony de Leon  Per K. Eide  Silvia Fossati  Steven M. Greenberg  Edith Hamel  Cheryl A. Hawkes  Maya Koronyo‐Hamaoui  Atticus H. Hainsworth  David Holtzman  Masafumi Ihara  Angela Jefferson  Raj N. Kalaria  Christopher M. Kipps  Katja M. Kanninen  Ville Leinonen  JoAnne McLaurin  Scott Miners  Tarja Malm  James A. R. Nicoll  Fabrizio Piazza  Gesine Paul  Steven M. Rich  Satoshi Saito  Andy Shih  Henrieta Scholtzova  Heather Snyder  Peter Snyder  Finnbogi Rutur Thormodsson  Susanne J. van Veluw  Roy O. Weller  David J. Werring  Donna Wilcock  Mark R. Wilson  Berislav V. Zlokovic  Ajay Verma.

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. Volume 12, Issue 1. 2020. 


A challenging diagnosis of reversible “vascular” dementia: Cerebral amyloid angiopathy-related inflammation

Poli, L., De Giuli, V., Piazza, F., ...Padovani, A., Pezzini, A.

Journal of Neuroimmunology, 2020, 338, 577109

2018


2015

Validation of Clinicoradiological Criteria for the Diagnosisof Cerebral Amyloid Angiopathy–Related Inflammation.

Eitan Auriel, MD, MSc; Andreas Charidimou, MD, PhD; M. Edip Gurol, MD, MSc; Jun Ni, MD; Ellis S. Van Etten, MD; Sergi Martinez-Ramirez, MD; Gregoire Boulouis, MD; Fabrizio Piazza, PhD; Jacopo C. DiFrancesco, MD, PhD; Matthew P. Frosch, MD, PhD; Octάvio M. Pontes-Neto, MD, PhD; Ashkan Shoamanesh, MD; Yael Reijmer, PhD; Anastasia Vashkevich, BA; Alison M. Ayres, BA; Kristin M. Schwab, BA; Anand Viswanathan, MD, PhD; Steven M. Greenberg, MD, PhD. 

JAMA Neurol. 2015 Dec 28:1-6. doi: 10.1001/jamaneurol.2015.4078. [Epub ahead of print]

Cerebrospinal Fluid Anti-Amyloid-β Autoantibodies and Amyloid PET in Cerebral Amyloid Angiopathy-Related Inflammation. 

Carmona-Iragui M, Fernández-Arcos A, Alcolea D, Piazza F, Morenas E, Antón-Aguirre S, Sala I, Clarimon J, Dols-Icardo O, Camacho V, Sampedro F, Munuera J, Nuñez-Marin F, Lleó A, Fortea J, Gómez-Ansón B, Blesa R.

J Alzheimers Dis. 2015 Nov 27


Recurrence of Cerebral Amyloid Angiopathy-Related Inflammation: A Report of Two Cases from the iCAβ International Network.

DiFrancesco JC, Touat M, Caulo M, Gallucci M, Garcin B, Levy R, Uncini A, Piazza F

J Alzheimers Dis. 2015 Jun 26;46(4):1071-1077


Anti-Aβ autoantibodies in amyloid related imaging abnormalities (ARIA): candidate biomarker for immunotherapy in Alzheimer’s disease and cerebral amyloid angiopathy

DiFrancesco JC, Longoni M and Piazza F (2015). 

Front. Neurol. 6:207. doi: 10.3389/fneur.2015.00207


Cerebral Amyloid Angiopathy-Related Inflammation: Report of a Case with Very Difficult Therapeutic Management

Crosta F, Orlandi B, De Santis F, Passalacqua G, DiFrancesco JC, Piazza F, Catalucci A, Desideri G and Marini C.

Case Reports in Neurological Medicine. Volume 2015 (2015), Article ID 483020, 5 pages. http://dx.doi.org/10.1155/2015/483020


Prodromal Alzheimer's disease presenting as cerebral amyloid angiopathy-related inflammation with spontaneous amyloid-related imaging abnormalities and high cerebrospinal fluid anti-Aβ autoantibodies

Boncoraglio GB, Piazza F, Savoiardo M, Farina L, DiFrancesco JC, Prioni S, Tagliavini F, Parati EA, Giaccone G.

J Alzheimers Dis. 2015;45(2):363-7

 

2014

Prodromal Alzheimer's Disease Presenting as Cerebral Amyloid Angiopathy-Related Inflammation with Spontaneous Amyloid-Related Imaging Abnormalities and High Cerebrospinal Fluid Anti-Aβ Autoantibodies

Boncoraglio GB*, Piazza F*, Savoiardo M, Farina L, DiFrancesco JC, Prioni S, Tagliavini F, Parati EA, Giaccone G.

J Alzheimers Dis. 2015;45(2):363-7  

2013

Anti-amyloid β autoantibodies in cerebral amyloid angiopathy-related inflammation: implications for amyloid-modifying therapies

Piazza F, Greenberg SM, Savoiardo M, Gardinetti M, Chiapparini L, Raicher I, Nitrini R, Sakaguchi H, Brioschi M, Billo G, Colombo A, Lanzani F, Piscosquito G, Carriero MR, Giaccone G, Tagliavini F, Ferrarese C, DiFrancesco JC.

Annals of  Neurology. 2013 Apr;73(4):449-58. doi: 10.1002/ana.23857. Epub 2013 Apr 26.