Research Interests

Chiral Separation, Chromatography, Molecular Simulations, Molecular Spectroscopy, Colloid Science

Our research centered around exploring molecular recognition mechanisms in chromatographic processes. A combination of experimental and theoretical approaches were employed to develop thermodynamic and kinetic models for chromatographic retention processes. By gaining a deeper understanding of retention and adsorption mechanisms, we have been able to optimize and investigate analytical methods based on these models.

Biography

Hung-Wei Tsui is an Associate Professor of Chemical Engineering at National Taiwan University. Born in Taipei, Taiwan, Dr. Tsui completed his BS in Chemical Engineering at National Taiwan University in 2005, followed by an MS in the same field from the same university in 2007, conducting research under Prof. Li-Jen Chen. He earned his PhD in Chemical Engineering from Purdue University in 2013, where his dissertation, under the guidance of Prof. Elias I. Franses and Prof. Nien-Hwa Linda Wang, focused on the chiral recognition mechanism of polysaccharide-type sorbents. Afterward, he undertook postdoctoral research at National Taiwan University with Prof. Li-Jen Chen in 2014, studying the effects of polyelectrolytes on surfactant micellization. He joined the National Taipei University of Technology as a faculty member in the spring of 2015 and was promoted to Associate Professor in 2020. In February 2024, he began serving as an Associate Professor in the Department of Chemical Engineering at National Taiwan University.

Selected Publications

Hung-Wei Tsui*, Si-Xian Huang, Ting-Hsien Tseng, "Heterogenous adsorption mechanisms for describing enantioselective retention in normal-phase liquid chromatography,"  J. Chromatogr. A, 1704, 464140 (2023).

Hung-Wei Tsui*, Song-Zhu Lin, Yu-Chia Hsu, Feng-Ji Dai, "Retention modeling and adsorption mechanisms in reversed-phase liquid chromatography," J. Chromatogr. A, 1662, 462736 (2022).

Hung-Wei Tsui*, Pei-Wen Ye, Si-Xian Huang, "Effect of solvents on the chiral recognition mechanisms of immobilized cellulose-based chiral stationary phase," J. Chromatogr. A, 1637, 461796 (2021). 

Ang-Yeh Lin, Kai-Tse Cheng, Sin-Chang Chen, Hung-Wei Tsui*, “Effect of solvent composition on the van’t Hoff enthalpic curve using amylose 3,5-dichlorophenylcarbamate–based sorbent,” J. Chromatogr. A, 1515, 179-186 (2017). 

Hung-Wei Tsui, Elias I. Franses, Nien-Hwa Linda Wang*, “Effect of alcohol aggregation on the retention factors of chiral solutes with an amylose-based sorbent: modeling and implications for the adsorption mechanism,” J. Chromatogr. A, 1328, 52-65 (2014). 

Hung-Wei Tsui, Nien-Hwa Linda Wang, Elias I. Franses*, “Chiral recognition mechanism of acyloin-containing chiral solutes by amylose tris[(S)-α-methylbenzylcarbamate],” J Phys. Chem. B 117, 9203–9216 (2013). 

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