OVERVIEW
The main focus of our research group is the adaptive responses induced by the restrictions in the oxygen supply to the tissues. Among these, special attention is focused on the central and peripheral physiological adjustments in response to programs of intermittent exposure to hypobaric hypoxia. This type of hypoxia exposure is a stimulus of interest in the physiology of exercise, for the aerobic performance improvement, and also as a triggering mechanism of the response of acclimatisation to high altitude. We have also studied other experimental models such as anaemia, induced hypoxemia and hypothermia.
We have also dedicated our attention to the functional study of bioactive food components. Our translational research focuses on the effect of nutraceutical products in combination with physical exercise and intermittent hypoxia and the potential favourable effect on metabolic diseases.
The research lines of the group include:
Interventions (nutrition, exercise, intermittent hypobaric hypoxia) to improve physiological markers of skeletal muscle injury recovery or general health status.
Capillarisation, morphometry and metabolic characterisation of skeletal muscle fibres.
Enteric microbiota alterations.
Oxidative stress during exercise, hypoxia and heat stress.
WORK IN PROGRESS
Between 2011-1013 we performed a coordinated research project entitled: Can intermittent hypoxia contribute to tissue repair? that has been executed through two different sub-projects: "Effect of intermittent hypobaric hypoxia on induced muscle injury repair in laboratory rats" carried out at the School of Biology (BKC Campus. PR: Ginés Viscor) and the second one "Neuropsychological repercussion of a cognitive, physical and intermittent hypobaric hypoxia program in traumatic brain injured patients" developed at the School of Medicine and Bellvitge University Hospital (HUBc Campus PR: Luisa Corral).
As a follow-up to the previous one, a new coordinated research project (2014-2017) entitled "Synergistic effect of cold and hypoxia on tissue repair" was funded in the 2013 call of Spain's Plan Nacional I+D+i. As in the previous case, this project was composed of two subprojects: Synergistic effect of cold and hypoxia in the repair of muscle damage in laboratory rats (executed at BKC Campus. PR: Ginés Viscor) and Synergistic effect of cold and hypoxia in skeletal muscle injury recovery (developed at HUBc Campus. PR: M.Isabel Miguel).
Recently, we have developed the research project "Edible microalgae to maintain energy homeostasis. Application to diet-induced metabolic syndrome, physical exercise and hypoxia", funded in the 2020 call of Spain's Plan Nacional I+D+i with PRs: Sara Ramos-Romero and Josep L Torres (IQAC-CSIC)
Most of our recent publications are derived from these projects.
Our research group is part of the Institute for Research in Nutrition and Food Safety of the University of Barcelona (INSA-UB). We are framed in the axis of Food, diet and health