PLGA

(Poly Lactide co Glycolide)

Manufacturer & Supplier of Polymers PLGA

(Poly Lactide co Glycolide) PLA (Poly Lactide) for Medical & Complex Drug Delivery Application


Table of Contents :

Bioresorbable polymers

Our Bioresorbable Polymers are utilized in Medical Applications throughout a numerous platform of controlled release Parenteral Drug Delivery and Medical Devices majorly in the following sectors:

→ Cardiovascular

→ Orthopedic

→ Dental

→ Ophthalmic

→ Neurologic regeneration

→ Wound care management

→ Advanced tissue engineering

Bioresorbable Polymers give a better platform to the formulation scientists, the possibility to design better drug delivery systems, which could lead to advanced efficacy, fewer side effects, and better compliance, leading to get improved outcome in patients.

Processing bioresorbable polymers Our bioresorbable polymers are compatible with melt and solvent based processing technologies. Through the knowledge,d skills and assistance of Nomisma’s scientists, in various fields like extrusion, injection molding, 3D printing, emulsion formulation, spray coating and laser cutting , may help to smoothen/speed up your development process.

Manufacturing facility Our bioresorbable polymers are produced in ISO 9001 certified facility to meet medical device standards and to comply with USP/NF General Chapter <1078> Good Manufacturing Practices for Bulk Pharmaceutical Excipients and The Joint IPEC-PQG Good Manufacturing Practices Guide for Pharmaceutical Excipients, 2017 as published under the auspices of the International Pharmaceutical Excipients Council for controlled-release drug delivery applications.

Packaging, storage and stability Our bioresorbable polymers are supplied in the form of powder in a packing of 50g, 100g, 250g, 500g & 1 kilogram consisting of an HDPE bottle & a secondary packing of aluminum bag containing silica gel. When stored in its prescribed packaging conditions, our bioresorbable polymers will meet the defined stability for the respective polymer.

Applications

Controlled Release Drug Delivery Formulation

Formulation developers are using self-absorbable polymers to create drug delivery systems that improve the patient’s health. Flexibility, convenience and better compliance to meet patient needs can all be incorporated into the system design process involving use of Proteins, vaccines, and other biological molecules. Scientists can use our polymer to develop & manufacture strategies of controlled release injectable depots, micro/nanoparticles and solid implants. API together with polymer and solvent is mixed to form a gel which is injected to the patient so that the drug can release as per the necessity. Prefabricated implants containing drugs can made by melt extrusion of drugs and polymers and implanted into the body by surgery or if small enough, they can be inserted through a well-known techniques

Medical Devices Bioresorbable Polymers are valuable additives with inside the design and manufacture of Medical Devices such as:

→ Screws

→ Plates and Bone regeneration scaffolds

→ Staples and Sutures

→ Neural conduits

→ Hernia meshes

→ Stents

→ Device coatings

→ Dental and Ophthalmic treatments Utilized for their structural characteristics,

bioresorbable polymers are resorbed through the body, doing away with the need for surgical elimination once the healing process is complete.

Product range

Poly (D, L-lactide-co-glycolide) (PLGA) Identification Polymer Ratio End Group Inherent Viscosity dl/g DLG 50-2A PLGA 50/50 COOH 0.15-0.25 DLG 50-3A PLGA 50/50 COOH 0.25-0.40 DLG 50-5A PLGA 50/50 COOH 0.40-0.55 DLG 50-6A PLGA 50/50 COOH 0.55-0.65 DLG 50-8A PLGA 50/50 COOH 0.75-0.85 DLG 50-2E PLGA 50/50 ESTER 0.15-0.25 DLG 50-6E PLGA 50/50 ESTER 0.55-0.65 DLG 50-7E PLGA 50/50 ESTER 0.60-0.70 DLG 50-6P PLGA-PEG 50/50 PEG 0.45-0.65 DLG 50-7P PLGA-PEG 50/50 PEG 0.65-0.80 LG 50-7E PLGA 50/50 ESTER 0.60-0.70 LG 50-2E PLGA 50/50 ESTER 0.15-0.25 LG 50-7A PLGA 50/50 COOH 0.60-0.70 LG 50-2A PLGA 50/50 COOH 0.15-0.25 DLG 75-2A PLGA 75/25 COOH 0.08-0.21 DLG 75-5A PLGA 75/25 COOH 0.38-0.64 DLG 75-7A PLGA 75/25 COOH 0.60-0.70 DLG 75-8A PLGA 75/25 COOH 0.70-0.90 DLG 75-10A PLGA 75/25 COOH 0.80-1.10 DLG 75-2E PLGA 75/25 ESTER 0.15-0.30 DLG 75-4E PLGA 75/25 ESTER 0.30-0.50 DLG 75-7E PLGA 75/25 ESTER 0.66-0.80 DLG 75-9E PLGA 75/25 ESTER 0.75-1.00 DLG 75-4A PLGA 75/25 COOH 0.30-0.50

Product range

LG 75-2E PLGA 75/25 ESTER 0.15-0.30 LG 75-9E PLGA 75/25 ESTER 0.75-1.00 LG 75-2A PLGA 75/25 COOH 0.15-0.30 LG 75-9A PLGA 75/25 COOH 0.75-1.00 DLG 85-2A PLGA 85/15 COOH 0.15-0.25 DLG 85-7A PLGA 85/15 COOH 0.55-0.75 DLG 85-7E PLGA 85/15 ESTER 0.55-0.75 DLG 85-12E PLGA 85/15 ESTER 1.00-1.30 DLG 45-2A PLGA 45/55 COOH 0.15-0.30 DLG 55-5A PLGA 55/45 COOH 0.40-0.50 DLG 65-3A PLGA 65/35 COOH 0.25-0.35 DLG 65-6A PLGA 65/35 COOH 0.50-0.65 DLG 90-5A PLGA 90/10 COOH 0.35-0.55 DLG 90-7A PLGA 90/10 COOH 0.60-0.75 DLG 95-2A PLGA 95/5 COOH 0.15-0.25 DLG 95-4A PLGA 95/5 COOH 0.25-0.50 DLG 65-6E PLGA 65/35 ESTER 0.50-0.65 DLL 10-15E P(L/DL) LA 10/90 Ester 1.30-1.70

Poly Lactide (PLA)

Identification Polymer Ratio End Group Inherent Viscosity DL 100-1A PDLLA 0/100 COOH 0.05-0.20 DL 100-2A PDLLA 0/100 COOH 0.15-0.30 DL 100-5A PDLLA 0/100 COOH 0.40-0.60 DL 100-7A PDLLA 0/100 COOH 0.60-0.80 DLL 10-15A P(L/DL)LA 90/10 COOH 1.30-1.70

Product range

L 100-1A PLLLA 0/100 COOH 0.05-0.20 L 100-2A PLLLA 0/100 COOH 0.15-0.30 L 100-5A PLLLA 0/100 COOH 0.40-0.60 L 100-7A PLLLA 0/100 COOH 0.60-0.80 L100-12A PLLA 0/100 COOH 0.9-1.2 DLL 10-15A P(L/DL)LA 10/90 COOH 1.30-1.70 DL 100-1E PDLLA 0/100 Ester 0.05-0.20 DL 100-2E PDLLA 0/100 Ester 0.15-0.30 DL 100-5E PDLLA 0/100 Ester 0.40-0.60 DL 100-7E PDLLA 0/100 Ester 0.60-0.80 DLL 10-15E P(L/DL)LA 90/10 Ester 1.30-1.70 L 100-1E PLLLA 0/100 Ester 0.05-0.20 L 100-2E PLLLA 0/100 Ester 0.15-0.30 L 100-5E PLLLA 0/100 Ester 0.40-0.60 L 100-7E PLLLA 0/100 Ester 0.60-0.80 L100-12E PLLA 0/100 Ester 0.9-1.2 DLL 10-15E P(L/DL)LA 10/90 Ester 1.30-1.70

L= L Lactide, D= D lactide, DL= DL-Lactide, G= Glycolide, A= Acid End group, E= Ester End group

Remarks: Elemental Impurities - conforms to the ICH Q3D requirements (Not measured for each lot). The Product conforms to the requirements of Global Green Creations, including ISO 9001:2015. The customer is not released from the obligation to conduct careful inspection and testing of incoming products. Products are available in non-GMP sample form; contact us for a quote on GMP manufacturing.

How to Place Order?

Step -01 Communicate with the below details to globalgreencreations@gmail.com→ Contact Detail → Delivery Address / Billing Address → Types of the Polymer to be purchased (As per catalog) → Quantity → GST No. if available.

Step-02 → Confirm your order by paying advance payment and send a payment receipt by mail Or send an approved purchase order by mail.

Step-03 → We will be dispatching the consignment within 2 to 4 weeks after the order is confirmed.

Appreciate technical Questions by mail to support the fulfilment for the choice of polymer.

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