Panday, U., Madhugiri, I., Gadgil, C. and Gadgil, M. (2024) Leveraging machine learning to dissect role of combinations of amino acids in modulating the effect of zinc on mammalian cell growth. Biotech Prog. 40(3):e3436
Rawat, J., Bhambri, A., Pandey, U., Banerjee, S., Pillai, B. and Gadgil, M. (2023) Amino acid abundance and composition in cell culture medium affects trace metal tolerance and cholesterol synthesis. Biotech Prog.39(1): e3298
Prabhu, A., Shanmugam, D. and Gadgil, M. (2022) Engineering nucleotide sugar synthesis pathways for independent and simultaneous modulation of N-glycan galactosylation and fucosylation in CHO cells. Metab Eng. 74: 61-71
Sreejan, A., Gadgil, M. and Gadgil, C. (2022) Mathematical model of the multi-amino acid multi-transporter system predicts uptake flux in CHO cells. J. Biotechnol. 344:40-49
Prabhu, A. and Gadgil, M. (2021) Trace metals in cellular metabolism and their impact on recombinant protein production. Process Biochem. 110: 251-262
Rawat, J. and Gadgil, M. (2020) Towards in situ continuous feeding via controlled release of complete nutrients for fed-batch culture of animal cells. Biochem. Eng. J. 154: 104736
Maralingannavar, V., Parmar, D., Panchagnula, V. and Gadgil, M. (2019) Superfluous glutamine synthetase (GS) activity in CHO cells selected under glutamine limitation is growth limiting in glutamine replete conditions and can be inhibited by serine. Biotech. Prog. 35(5):e2856
Prabhu, A., Gadre, R.V. and Gadgil, M. (2018) Zinc supplementation decreases galactosylation of recombinant IgG in CHO cells. Appl Microbiol & Biotech 1-11
Maralingannavar, V., Shenoy, B.R., Hazarika, J., Unnikrishnan, D., Prabhu, A., Maity, S.*, Gadgil, M.* (2018) In situ base release for pH maintenance can allow shake flasks to better mimic bioreactor performance for CHO cell culture. J Chem Tech & Biotech 93: 2842–2850
Maralingannavar, V., Parmar, D., Pant, T., Gadgil, C., Panchagnula, V. and Gadgil, M. (2017) CHO cells adapted to inorganic phosphate limitation show higher growth and higher pyruvate carboxylase flux in phosphate replete conditions. Biotech. Prog 33(3):749-758
Gadgil, M. (2017) Cell culture processes for biopharmaceutical manufacturing. Current Science 112(7): 1478-88
Rawat, J. and Gadgil, M. (2016) Shear increases cytotoxicity and reduces transfection efficiency of liposomal gene delivery to CHO-S cells. Cytotechnology 68(6): 2529-2538
Surve, T. and Gadgil, M. (2015) Manganese increases high mannose glycoform on monoclonal antibody expressed in CHO when glucose is absent or limiting: Implications for use of alternate sugars. Biotech Prog 31(2):460-7
Le, H., Vishwanathan, N., Jacob, N., Gadgil, M., and Hu, W.-S.* (2015) Cell Line Development for Biomanufacturing Processes: Recent Advances and An Outlook. Biotech Lett. 37(8):1553-64
Gadgil, M. (2015) Development of a mathematical model for animal cell culture without pH control and its application for evaluation of clone screening outcomes in shake flask culture, J Chem Tech Biotech90(1):166-175
Sanil, R., Maralingannavar, V. and Gadgil, M. (2014) In situ pH management for microbial culture in shake flasks and its application to increase plasmid yield. J Ind Microbiol Biotech 41 (4): 647-655
Nisal, A., Trivedy, K., Mohammad, H., Panneri, S., Sen Gupta, S.*, Lele, A. K.*, Manchala, R., Kumar, N., Gadgil, M., and Khandelwal, H.,(2014) The uptake of azo dyes into silk glands for production of colored silk cocoons using the green feeding approach, ACS Sustainable Chem Eng 2 (2): 312–317
Vijayan, V., Deshpande, P., Gadgil, C.J. and Gadgil, M. (2013) Comparison of methods for identifying periodically varying genes. Intl J of Bioinf Res Appl. 9(1):53-70
Pant, T., Pradhan, K., and Gadgil,M.(2012) In situ pH maintenance for mammalian cell cultures in shake flasks and tissue culture flasks. Biotech Prog 28(6):1605-10
Hegde, S., Pant, T., Pradhan, K., Badiger, M., Gadgil,M.* (2012) Controlled release of nutrients to mammalian cells cultured in shake flasks. Biotech Prog. 28(1):188-95
Agrawal, M. and Gadgil, M. (2012) Meta analysis of gene expression changes upon treatment of A549 cells with anti-cancer drugs to identify universal responses. Comput Biol Med. 42(11):1141-9
Pradhan, K. and Gadgil, M. (2012) Effect of addition of ‘carrier’ DNA during transient protein expression in suspension CHO culture. Cytotechnology 64(6):613-22
Roshan, R., Ghosh, T., Gadgil, M. and Pillai, B. (2012) Regulation of BACE1 by miR-29a/b in a cellular model of Spinocerebellar ataxia 17. RNA Biol. 9(6):891-9
Thombre, S. and Gadgil, M. (2011) Increase in efficiency of media utilization for recombinant protein production in CHO culture through dilution. Biotechnol Appl Biochem. 58(1):25-31
Vijayan, V., Bulsara, B., Gadgil, C.J., Gadgil, M. (2009) Comparison of feature selection and classification combinations for cancer classification using microarray data. Intl J of Bioinf Res Appl. 5(4): 417-431
Gadgil, M., (2008) A Population Proportion approach for ranking differentially expressed genes. BMC Bioinformatics 9(1):380
Gadgil, M., Mehra, S., Kapur, V. and Hu, W.-S. (2006) TimeView: For comparative gene expression analysis. Applied Bioinformatics 5(1):41-4 Download TimeView
Gadgil, M., Kapur, V, and Hu, W.-S. (2005) Transcriptional response of E. coli to temperature shift. Biotechnol Prog. 21(3):689-699
Gadgil, M., Lian, W., Gadgil, C., Kapur, V. and Hu, W.-S. (2005) An analysis of the use of genomic DNA as a universal reference in two channel DNA microarrays. BMC Genomics. 6(1):66
Kulkarni, A., Gadgil (née Deshpande), M. and Pandit, A. B. (2000) Techniques of wastewater treatment. Resonance 5(11): 56-68
Kulkarni, A., Gadgil (née Deshpande), M., Pandit, A. B. (2000) Techniques of wastewater treatment 2. Future technologies. Resonance 5(12): 64-74
Mugdha Gadgil and Wei-Shou Hu (2017) Cell line development for biomanufacturing processes in Biochemical Engineering and Process Technologies. In production. New Series of Biotechnology. Editors Stephanapoulus, G., Nielsen, J., Lee, S.Y. John Wiley and Sons.
Trent Carrier and Mugdha Gadgil. Increasing Performance of Mammalian Expression Platforms in Advances in Large-Scale Biopharmaceutical Manufacturing and Scale-Up Production, 2nd edition, October 2007, Editor Eric Langer, ASM Press
Gadgil, M. (2016) Recombinant biopharmaceuticals: evolution and screening for mammalian cell clones. Indo-US Workshop on Cell Factories at IIT-Bombay, Mumbai
Gadgil, M. (2010) Drug target identification: Statistical methods for transcriptomic data analysis. Invited lecture in Workshop‐Symposium on Mathematics in Drug Discovery, Pune
Gadgil, M. and Feldman, S. (2005) Transient expression and stable cell line development. PD Direct Seminar Series, Boston, MA; San Fransisco, CA; San Diego, CA.
A method for sustaining a cell culture system using a hydrogel composition. Rawat, J., Gadgil, M. 2019. Provisional application in India 201911023888
In situ pH management using hydrogel and applications thereof. Gadgil, M. 2017. US Patent 9,677,046; Pending application EP2885401A1; India 307912
Zinc supplementation to decrease galactosylation. Gadgil, M., Prabhu, A., Gadre, R. 2017 Provisional application in India 201711036685
Iron Transport and Metabolism proteins. Kapur, V., Gadgil, M. and Hu, W.-S. 2003 International Patent Application #PCT/US03/26488. (Licensed by Epitopix Inc. through the University of Minnesota)