Publications

Valencia J, M Fernández-Sevilla L, Fraile-Ramos A, Sacedón R, Jiménez E, Vicente A, Varas A.

Acute Lymphoblastic Leukaemia Cells Impair Dendritic Cell and Macrophage Differentiation: Role of BMP4.

Cells. 2019 Jul 14;8(7). pii: E722. doi: 10.3390/cells8070722.

Herranz G, Aguilera P, Dávila S, Sánchez A, Stancu B, Gómez J, Fernández-Moreno D, de Martín R, Quintanilla M, Fernández T, Rodríguez-Silvestre P, Márquez-Expósito L, Bello-Gamboa A, Fraile-Ramos A, Calvo V, Izquierdo M.

Protein Kinase C δ Regulates the Depletion of Actin at the Immunological Synapse Required for Polarized Exosome Secretion by T Cells

Front Immunol. 2019 Apr 26;10:851. doi: 10.3389/fimmu.2019.00851. eCollection 2019.

Giovannone A.J., Reales E., Bhattaram P., Fraile-Ramos A., Weimbs T.

Tracking Endocytosis and Intracellular Trafficking of Epitope- tagged Syntaxin 3 by Antibody Feeding in Live, Polarized MDCK Cells

Bio Protoc. Feb 5; 8(3): e2453 (2018). DOI: 10.21769/BioProtoc.2453

Giovannone A.J., Reales E., Bhattaram P., Fraile-Ramos A.*, Weimbs T.*

Mono-ubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes

Mol Biol Cell, vol 28(21): 2843 (2017). DOI: 10.1091/mbc.E17-07-0461

*co-corresponding authors

de Wit R.H., Mujić-Delić A., van Senten J.R., Fraile-Ramos A., Siderius M., Smit M.J.

Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells

Oncotarget. doi: 10.18632/oncotarget.11817 (2016)

Raquel Bello-Morales, Antonio Jesús Crespillo, Alberto Fraile-Ramos, Enrique Tabarés, Antonio Alcina, José Antonio López-Guerrero

Role of the small GTPase Rab27a during the Herpes simplex virus infection of oligodendrocytic cells

BMC Microbiology, vol 12(1): 265 (2012) DOI:10.1186/1471-2180-12-265

Cepeda V., Fraile-Ramos A.

A role for the SNARE protein Syntaxin 3 in human cytomegalovirus morphogenesis.

Cell Microbiol, vol 13: 846-58 (2011)

Alonso R., Mazzeo C., Rodríguez M.C., Marsh M., Fraile-Ramos A., Calvo V., Avila-Flores A., Mérida I., Izquierdo M.

Diacylglycerol kinase alpha regulates the formation/maturation of multivesicular bodies containing lethal exosomes in living T lymphocytes.

Cell Death Differ, vol 18:1161-73 (2011)

Fraile-Ramos A.*, Cepeda V., Elstak E., van der Sluijs P.

Rab27a is required for human cytomegalovirus assembly

PLoS One, vol 5: doi:10.1371/journal.pone.0015318 (2010) * corresponding author

Bongers G., Maussang D., Muniz L., Noriega V., Fraile-Ramos A., Barker N., Marchesi F., Thirunarayanan N., Vischer H., Quin L., Mayer L., Harpaz N., Leurs R., Furtado G., Clevers H., Tortorella D., Smit M., Lira S. The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia.J Clin Invest, vol 120: 3969-78 (2010)

Slinger E., Maussang D., Siderius M., Rahbar A., Fraile-Ramos A., Lira S., Söderberg-Nauclér C., Leurs R., Smit M.

HCMV-encoded chemokine receptor US28 mediates proliferative signaling by establishing a positive feedback loop via activation of the IL-6/STAT3 axis.

Sci Signal vol 3: ra58 (2010)

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Chichon J., Rodriguez M.J., Fernández J.J., Fraile-Ramos A., Esteban M., Risco C., Carrascosa J.L.

Membrane remodeling during vaccinia virus morphogenesis.

Biol Cell vol 101: 401-414 (2009)

Fraile-Ramos A.*, Pelchen-Mathews A., Risco C., Rejas M.T., Emery V.C., Hassan-Walker A.F., Esteban M., Marsh M.

The ESCRT machinery is not required for human cytomegalovirus assembly.

Cell Microbiol, vol 9: 2955-2967 (2007) * corresponding author

Fontana J., Tzeng W.-P., Calderita G., Fraile-Ramos A., Frey T.K. and Risco C.

Novel replication complex architecture in rubella replicon-transfected cells.

Cell Microbiol, vol 9: 875-890 (2007)

Martini L., Hastrup H., Holst B., Fraile-Ramos A., Marsh M., Schwartz, T.W.

NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype

Mol Pharmacol, vol 62: 30-37 (2002)

Fraile-Ramos A., Pelchen-Matthews A., Kledal T. N., Browne H., Schwartz T. W., Marsh M.

Localization of Human Cytomegalovirus US27 and UL33 Proteins in Endocytic Compartments and Viral Membranes

Traffic, vol 3: 218-232 (2002)

Fraile-Ramos A., Kledal T. N., Pelchen-Matthews A., Bowers K., Schwartz T. W., Marsh M.

The Human Cytomegalovirus US28 Protein Is Located in Endocytic Vesicles and Undergoes Constitutive Endocytosis and Recycling

Mol Biol Cell, vol. 12: 1737-1749 (2001)

Pelchen-Matthews A., Signoret N., Klasse P.J., Fraile-Ramos A., Marsh M.

Chemokine-receptor trafficking and viral replication

Immunol Rev, vol. 168: 33-49 (1999)

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