Конечно-систолическое отношение объема и давления

End systolic pressure-volume relationship (ESPVR)

ESPVR describes the maximal pressure that can be developed by the ventricle at any given LV volume. This implies that the PV loop cannot cross over the line defining ESPVR for any given contractile state.

The slope of ESPVR (Ees) represents the end-systolic elastance, which provides an index of myocardial contractility. The ESPVR is relatively insensitive to changes in preload, afterload, and heart rate. This makes it an improved index of systolic function over other hemodynamic parameters like ejection fraction, cardiac output, and stroke volume.

• The ESPVR becomes steeper and shifts to the left as inotropy (contractility) increases.

• The ESPVR becomes flatter and shifts to the right as inotropy decreases.