Publications

Méthodologie Statistique

1. E Ollier, A Samson, X Delavenne, V Viallon (2016)  A SAEM algorithm for fused lasso penalized non-linear mixed effect models: application to group comparison in pharmacokinetics. Computational Statistics & Data Analysis 95:207-221 (Preprint)

2. E Ollier, V Viallon (2017) Regression modeling on stratified data with the lasso. Biometrika 104(1):83-96 (Preprint)

3. G Fort, E Ollier, A Samson (2019) Stochastic Proximal Gradient Algorithms for Penalized Mixed Models. Statistics and Computing  (Preprint)

4. E Ollier, P Blanchard, G Le Teuff, S Michiels (2021) Penalized Poisson model for network meta-analysis of individual patient time-to-event data. Statistics in Medicine (Preprint)

5. E Ollier (2022) Fast selection of nonlinear mixed effect models using penalized likelihood. Computational Statistics & Data Analysis (Preprint)

6. C Chapelle, G Le Teuff, P Zufferey, S Laporte, E Ollier (2023) A framework to characterise the reproducibility of meta-analysis results with its application to direct oral anticoagulants in the acute treatment of venous thromboembolism. Research Synthesis Methods

Modélisation en Pharmacologie

1. X Delavenne, E Ollier, T Basset, L Bertoletti, S Accassat, A Garcin, S Laporte, P Zufferey, P Mismetti (2013) A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin. British Journal of Clinical Pharmacology 76(1):107-13

2. E Ollier, F Heritier, C Bonnet, S Hodin, B Beauchesne, S Molliex, X Delavenne (2015) Population pharmacokinetic model of free and total ropivacaine after TAP nerve block in patients undergoing liver resection. British Journal of Clinical Pharmacology 80(1):67-74

3. E Ollier, S Hodin, T Basset, S Accassat, L Bertoletti, P Mismetti, X Delavenne (2015) In vitro and in vivo evaluation of drug-drug interaction between dabigatran and proton pump inhibitors. Fundamental & Clinical Pharmacology 29(6):604-614

4. E Ollier, S Hodin, J Lanoiselée, J Escal, S Accassat, E De Magalhaes, T Basset, L Bertoletti, P Mismetti, X Delavenne (2017) Effect of activated charcoal on rivaroxaban complex absorption. Clinical Pharmacokinetics 56(7):793-801

5. E Ollier, P Mazzocco, D Ricard, G Kaloshi, A Idbaih, A Alentorn, D Psimaras, J Honnorat, JY Delattre, E Grenier, F Ducray, A Samson (2017) Analysis of temozolomide resistance in low-grade gliomas by using a mechanistic mathematical model. Fundamental & Clinical Pharmacology 31(3):347-58

6. X Delavenne, E Ollier, S Chollet, F Sandri, J Lanoiselée, A Montmartin, JF Fuselier, P Mismetti, L Gergele (2017) PK/PD model to optimize unfractionated heparin dosing regimen during cardiopulmonary bypass. British Journal of Anaesthesia 118(5):705-712

7. J Lanoiselée, P Zufferey, E Ollier, S Hodin, X Delavenne (2017) Is Tranexamic Acid ExposureRelated to Blood Loss in Hip Arthroplasty ? A Pharmacokinetic-Pharmacodynamic Study. British Journal of Clinical Pharmacology 84(2):310-319

8. P Zufferey, E Ollier, X Delavenne, S Laporte, P Mismetti, SB Duffull (2018) Incidence and risk factors of major bleeding following major orthopaedic surgery with fondaparinux thromboprophylaxis. A times-to-event analysis. British Journal of Clinical Pharmacology

9. X Delavenne, Y Dargaud, E Ollier, C Negrier (2019) Dose tailoring of human cell line-derived recombinant factor VIII (simoctocog alfa, Nuwiq®) using a limited sampling strategy in patients with severe hemophilia A. British Journal of Clinical Pharmacology

10. X Delavenne, E Ollier, A Lienhart, Y Dargaud (2020) A new paradigm for personalized prophylaxis for patients with severe haemophilia A. Haemophilia.

11. J Lanoiselée, P Zufferey, S Hodin, N Tamisier, L Gergelé, JC Palao, S Campisi, S Molliex, J Morel, X Delavenne, E Ollier (2020) Pharmacokinetic model for cefuroxime dosing during cardiac surgery under cardiopulmonary bypass. Antimicrobial Agents and Chemotherapy

12. J Lanoiselée, R Chaux, S Hodin, S Bourayou, A Gibert, R Philippot, S Moliex, PJ Zufferey, X Delavenne, E Ollier (2021) Population pharmacokinetic model of cefazolin in total hip arthroplasty. Scientific Reports, 11(1), 1-11.

13. R Chaux, J Lanoiselée, C Magand, PJ Zufferey, X Delavenne, E Ollier (2022) Robust K-PD model for activated clotting time prediction and UFH dose individualisation during cardiopulmonary bypass. Computer Methods and Programs in Biomedicine.

14. A Gibert, J Lanoiselée, I Gouin-Thibault, A Pontis, K Azarnoush, A Petrosyan, N Grand, S Molliex, J Morel, L Gergelé, S Hodin, V Bin, R Chaux, X Delavenne, Ollier, E. (2024). Factors Influencing Unfractionated Heparin Pharmacokinetics and Pharmacodynamics During a Cardiopulmonary Bypass. Clinical Pharmacokinetics.

Méta-analyse, méta-recherche

1. S Laporte, C Chapelle, L Bertoletti, E Ollier, P Zufferey, JC Lega, A Merah, H Décousus, S Schulman, G Meyer, M Cucherat, P Mismetti (2017)  Assessment of clinically relevant bleeding as a surrogate outcome for major bleeding.Validation by meta-analysis of randomized controlled trials. Journal of Thrombosis and Haemostasis. 

2. JC Trone, E Ollier,  C Chapelle,  L Bertoletti,  M. Cucherat,  P. Mismetti,  N. Magné,  S. Laporte (2018) Statistical Controversies in Clinical Research: Limitations of open-label studies assessing antiangiogenic therapies with regard to evaluation of vascular adverse drug events. A meta-analysis. Annals of Oncology

3. G Claisse, P Zufferey, JC Trone, N Maillard, X Delavenne, S Laporte, E Ollier (2019)   Predicting the dose of vancomycin in ICU patients receiving different types of RRT therapy: a model-based meta-analytic approach. British Journal of Clinical Pharmacology 85(6):1215:26

4. S Laporte, C Chapelle, JC Trone, L Bertoletti, P Girard, G Meyer,  M Safieddine, M Cucherat, E Ollier, P Mismetti (2020) Early detection of the existence or absence of treatment effect: a cumulative meta-analysis. Journal of Clinical Epidemiology.

5. JC Trone, A Vallard, S Sotton, M Ben Mrad, O Jmour, N Magné, B Pommier, S Laporte, E Ollier (2020). Survival after hypofractionation in glioblastoma: a systematic review and meta-analysis. Radiation Oncology, 15, 1-10.

6. JC Trone, E Ollier, C Chapelle, P Mismetti, M Cucherat, N Magné, PJ Zuffrey, S Laporte (2020). Assessment of non-inferiority with meta-analysis: example of hypofractionated radiation therapy in breast and prostate cancer. Scientific Reports, 10(1), 1-9.

7. M Safieddine, C Chapelle, E Ollier, C Ferdynus, L Bertoletti, P Mismetti,  M Cucherat, S Laporte. (2020). Compared to randomized studies observational studies may overestimate the effectiveness of DOACs: a meta-epidemiological approach. Journal of Clinical Epidemiology

8. PJ Zufferey, J Lanoiselee, B Graouch, B Vielle, X Delavenne, E Ollier (2021) Exposure-Response Relationship of Tranexamic Acid in Cardiac Surgery: A Model-based Meta-analysis. Anesthesiology 134 (2), 165-178.

9.  C Chapelle, E Ollier, P Girard, C Frere, P Mismetti, M Cucherat, S Laporte (2021)  An Epidemic of Redundant Meta-analyses. Journal of Thrombosis and Haemostasis

10. E Ojardias, E Ollier,L Lafaie, T Celarier, P Giraux, L Bertoletti (2022) Time course of botulinum toxin dose response   after a single injection in adult post-stroke spasticity: systematic review and model-based meta-analysis.  Annals of  Physical and Rehabilitation Medicine.

11. T Solé, L Januel, A Denneval, N Williet, C Breton, P Blanc, E Ollier (2022) Time impact on the anti-diabetic effects of key bariatric surgeries: a network meta-analysis of randomized controlled trials with meta-regression. Surgery for Obesity and Related Diseases.

12. C Chapelle, E Ollier, P Bonjean, C Locher, P Zufferey, M Cucherat, S Laporte (2023) Replication of systematic reviews: is it to the benefit or detriment of methodological quality? Journal of Clinical Epidemiology.

13. PJ Zufferey, R Chaux, PA Lachaud, X Capdevila, J Lanoiselée, E Ollier (2024) Dose–response relationships of intravenous and perineural dexamethasone as adjuvants to peripheral nerve blocks: a systematic review and model-based network meta-analysis. British Journal of Anaesthesia.

Recherche Clinique, Epidémiologie  

1. LJ Pilaz, D Patti, G Marcy, E Ollier, S Pfister, RJ Douglas, M Betizeau, E Gautier, V Cortay, N Doerflinger, H Kennedy, C Dehay (2009) Forced G1-phase reduction alters mode of division,neuron number, and laminar phenotype in the cerebral cortex. PNAS vol 106(51): 21924-21929 

2. E Ollier, X Delavenne. (2015). Données pharmacologiques utiles pour une bonne utilisationdes anticoagulants oraux directs. Thérapie, 70(3), 243-249. 

3. T Boilot,T Raia-Barjat, E Ollier, C Chapelle, S Laporte, C Chauleur (2015) Influence d’un traitement anticoagulant pendant la grossesse sur l’anesthésie per-partum et les modalités d’accouchement. Gynécologie Obstétrique & Fertilité, 43(7):502-508 

4. JB Guy, AT Falk, P Auberdiac, L Cartier, A Vallard, E Ollier, JC Trone, M Khodri, C Chargari, N Magné (2015) Dosimetric study of volumetric arc modulation with RapidArc and intensity-modulated radiotherapy in patients with cervical cancer and comparison with 3-dimensional conformal technique for definitive radiotherapy in patients with cervical cancer. Medical Dosimetry. 

5. B Méry, A Vallard, JC Trone, C Pacaut, JB Guy, S Espenel,  J Langrand-Escure, E Ollier, G Wang, P Diao, L Bigot, S Mengue Ndong, C Bosacki, M Ben Mrad, N Magné. (2015) Correlation between anthropometric parameters and acute skin toxicity in breast cancer radiotherapy patients: a pilot assessment study. The British Journal of Radiology 

6. L Bertoletti, E Ollier, C Duvillard, X Delavenne, MN Beyens, ED Magalhaes, F Bellet, T Basset, P Mismetti, S Laporte (2016) Direct oral anticoagulants: Current indications and unmet needs in the treatment of venous thromboembolism. Pharmacological Research 

7. P Jullien, B Seitz Polski, N Maillard, D Thibaudin, B Laurent, E Ollier, E Alamartine, G Lambeau, C Mariat. Anti-phospholipase A2 receptor antibody levels at diagnosis predicts spontaneous remission of idiopathic membranous nephropathy. Clin Kidney J. 2017 Apr;10(2):209-214 

8. JC Trone, S Espenel, A Rehailia, E Guillaume, N Vial, C Rancoule, C Rodriguez-Lafrasse, M Ben Mrad, A El Meddeb Hamrouni, E Ollier, C Chargari, E Deutsch, A Vallard, N Magné (2017) Navigating the highlights of phase III trials: a watchful eye on evidence-based radiotherapy. Annals of Oncology 

9. C Batailler, N Bonin, M Wettstein, A Nogier, S Martres, E Ollier, O May, S Lustig (2017) Outcomes of Cup Revision for Ilio-Psoas Impingement after Total Hip Arthroplasty: Retrospective Study of 46 Patients. Orthopaedics & Traumatology: Surgery & Research 

10. W Guicherd, N Bonin, T Gicquel, JE Gedouin, X Flecher, M Wettstein, M Thaunat, N Prevost, E Ollier, O May (2017). Endoscopic or arthroscopic iliopsoas tenotomy for iliopsoas impingement followingtotal hip replacement. A prospective multicenter 64-case series. Orthopaedics & Traumatology: Surgery & Research. 

11. JB Guy, B Méry, E Ollier, S Espenel, A Vallard, AS Wozny, S Simonet, A Lauret, P Battiston-Montagne,  D Ardail, G Alphonse, C Rancoule,  C Rodriguez-Lafrasse, N Magné (2017) Dual “mAb” HER family blockade in head and neck cancer human cell lines combined with photon therapy. Scientific Reports

12. L Chambard, N Girard, E Ollier, JC Rousseau, F Duboeuf, MC Carlier, M Brevet, P Szulc, JB Pialat, J Wegrzyn, P Clezardin, CB Confavreux (2018) Bone, muscle and metabolic parameters predict survival in patients with synchronous bone metastases from lung cancers. Bone 108:202-209.

13. A Bellesoeur, E Ollier, M Allard, L Hirsch, P Boudou-Rouquette, J Arrondeau, A Thomas-Schoemann, M Tiako, N Khoudour, J Chapron, F Giraud, M Wislez, D Damotte, A Lupo, M Vidal, J Alexandre, F Goldwasser, M Tod, B Blanchet. Is there an Exposure–Response Relationship for Nivolumab in Real-World NSCLC Patients? Cancers 2019, 11, 1784.

14. B Pommier, E Ollier, JB Pelletier, X Castel, F Vassal, MC Tetard (2020). Conservative versus surgical treatment for odontoid fracture: Is the surgical treatment harmful? Systematic review and meta-analysis. World Neurosurgery.

15. P Guedeney, S Sorrentino, G Giustino, C Chapelle, S Laporte, BE Claessen, E Ollier, A Camaj, DN Kalkman, B Vogel, S De Rosa, C Indolfi, B Lattuca, M Zeitouni, M Kerneis, J Silvain, JP Collet, R Mehran, G Montalescot. Indirect Comparison of the Efficacy and Safety of Alirocumab and Evolocumab: A Systematic Review and Network Meta-Analysis. Eur Heart J Cardiovasc Pharmacother. 2020

16. B Tardy‐Poncet, B Play, A Montmartin, P Damien, E Ollier, E Presles, A Garcin, B Tardy (2021). PHILEOS (haemoPHILia and ostEoporOSis) Study: protocol of a multicentre prospective case–control study. BMJ open, 11(1), e042283.

17. C Le Terrier, M Vinetti, P Bonjean, R Richard, B Jarrige, B Pons,..., E Ollier,..., G Thiéry (2021). Impact of a restrictive antibiotic policy on the acquisition of extended-spectrum beta-lactamase-producing Enterobacteriaceae in an endemic region: a quasi-experimental, before-and-after, propensity-matched cohort study in a Caribbean intensive care unit. Critical Care, 2021 25:261.

18. V Mismetti, X Delavenne, D Montani, S Bezzeghoud, O Delezay, S Hodin, ... & V Cottin. (2023). Proteomic biomarkers for survival in systemic sclerosis-associated pulmonary hypertension. Respiratory Research, 24(1), 273.