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Microbial diversity : Polyphasic approach
Microbial diversity : Polyphasic approach
Development of biotechnologies and their industrial applications depend heavily on systematics. Identification of microorganisms and their application in Biotechnology process, depending on the place within the phylogenetic framework. and taxonomically unassigned strains needs to be characterized by a wide range of approaches to obtain a broad range of informative data from the genetic and epigenetic level, including morphology, physiology, chemistry, DNA patterns, gene sequences and whole genome hybridization. My lab is very much focused on identifying the new organisms from different niches.
Development of biotechnologies and their industrial applications depend heavily on systematics. Identification of microorganisms and their application in Biotechnology process, depending on the place within the phylogenetic framework. and taxonomically unassigned strains needs to be characterized by a wide range of approaches to obtain a broad range of informative data from the genetic and epigenetic level, including morphology, physiology, chemistry, DNA patterns, gene sequences and whole genome hybridization. My lab is very much focused on identifying the new organisms from different niches.
Plant-Microbe interaction (PGPR)
Plant-Microbe interaction (PGPR)
The population growth in the world is outstripping food supply and agricultural productivity. While agricultural production is growing at slower rate of about annually. The “green revolution” increased wheat production 10-fold in India, thereby feeding three times as many people. However this revolution has already been exploited to its limits and alternative solutions are required to be embarked upon through integration of classical breeding and advanced techniques in crop production and biotechnology to create “evergreen revolution” on sustainable basis. My lab is studying Plant growth-promoting rhizobacteria (PGPR) having beneficial root-association that improves plant health and/or growth by diverse mechanisms.
The population growth in the world is outstripping food supply and agricultural productivity. While agricultural production is growing at slower rate of about annually. The “green revolution” increased wheat production 10-fold in India, thereby feeding three times as many people. However this revolution has already been exploited to its limits and alternative solutions are required to be embarked upon through integration of classical breeding and advanced techniques in crop production and biotechnology to create “evergreen revolution” on sustainable basis. My lab is studying Plant growth-promoting rhizobacteria (PGPR) having beneficial root-association that improves plant health and/or growth by diverse mechanisms.
Microbial metabolites
Microbial metabolites
What should we screen” in the actinomycetes for novel antibiotics. Till date 10–103 Actinomycetes were screened for the isolation of actinomycin, 104 for chloramphenicol, 105for vancomycin, 106 for erythromycin, 107for daptomycin, we stopped here. To isolate novel antibiotics the number of screened strains has to be enlarged to 108 or more, or novel and unusual isolates, which have never been screened have to be used. Another important theme of my lab to screen new/rare actinomycetes for new candidate molecule to combat the drug resistance, by employing gene-genome approach.
What should we screen” in the actinomycetes for novel antibiotics. Till date 10–103 Actinomycetes were screened for the isolation of actinomycin, 104 for chloramphenicol, 105for vancomycin, 106 for erythromycin, 107for daptomycin, we stopped here. To isolate novel antibiotics the number of screened strains has to be enlarged to 108 or more, or novel and unusual isolates, which have never been screened have to be used. Another important theme of my lab to screen new/rare actinomycetes for new candidate molecule to combat the drug resistance, by employing gene-genome approach.
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