Davide salzano

POSTDOC

Short Bio

Davide Salzano is a postdoc working at the Scuola Superiore Meridionale under the supervision of prof. Mario di Bernardo.

His research deals with the application of dynamical systems and control theory for the development of synthetic microbial consortia in biomedical application (i.e. development of personalized therapies).

He got a dual award PhD title in Information and Communication Thechnology for Health (University of Naples Federico II) and Engineering Mathematics (University of Bristol). Previously, he worked at the University of Bristol under the supervision of prof. N. Savery, prof. C. Grierson, prof. M. di Bernardo and prof. L. Marucci. In March 2019 he obtained his master degree in Automation Engineering at the University of Naples Federico II, with the highest marks in all courses. His master thesis focused on the control of stochastic multiagent systems for applications in Synthetic Biology, in collaboration with the University of Bristol.

Publications

Under revision

2025

1. Martinelli, Vittoria, et al. "Multicellular PID control for robust regulation of biological processes." Journal of the Royal Society Interface 22.222 (2025): 20240583. 

2. M. Coraggio, D. Salzano, M. di Bernardo, "Controlling Complex Systems", Encyclopedia of Systems and Control Engineering, Elsevier, 2025.

3. D. Salzano, B. Shannon, C. Grierson, L. Marucci, N. J. Savery, M. di Bernardo, "In-vivo multicellular control of gene expression in microbial consortia", ACS Synthetic Biology (accepted for publication), 2025.

2024

1. S. M. Brancato, D. Salzano, D. Fiore, G. Russo, M. di Bernardo, "Ratiometric control of two microbial populations in a dual chamber bioreactor", IEEE Control Systems Letters, 2024, Early Access .

2. S. M. Brancato, D. Salzano, F. De Lellis, D. Fiore, G. Russo, M. di Bernardo, "In vivo learning-based control of microbial populations density in bioreactors", accepted for oral presentation at Learning 4 Dynamics and Control, 2024, arXiv:2312.09773.

2023

1. V. Martinelli, D. Salzano, D. Fiore, M. di Bernardo, "Multicellular PD control in microbial consortia", IEEE Control Systems Letters, 2023. The contents of this paper were also selected by CDC 2023 Program Committee for presentation at the Conference.

2. S. Brancato, F. De Lellis, D. Salzano, G. Russo, M. di Bernardo, "External control of a genetic Toggle Switch via Reinforcement Learning", 2023 European Control Conference (ECC) , 2023 .

3. N. Karagiannis-Axypolitidis, D. Salzano, D. Fiore, F. Cartenì, S. Mazzoleni, M. di Bernardo, F. Giannino, “A periodic open-loop strategy to mitigate plant-soil negative feedback”, 2023 European Control Conference (ECC) , 2023.

2022

1. I. de Cesare, I.,D. Salzano, M. di Bernardo, L. Renson, L. Marucci, "Control-based continuation: a new approach to prototype synthetic gene networks". ACS Synthetic Biology 2022 11 (7), 2300-2313. 

2. V. Martinelli*, D. Salzano*, D. Fiore, M. di Bernardo, "Multicellular PI control for gene regulation in microbial consortia", IEEE Control Systems Letters, 2022, vol. 6, pp. 3373-3378,

3. D. Salzano, D. Fiore, M. di Bernardo, "Ratiometric control of cell phenotypes in monostrain microbial consortia", Journal of the Royal Society Interface, 2022, 19.192: 20220335.

2021

1. V. Fusco*, D. Salzano*, D. Fiore, M. di Bernardo, "Embedded control of cell growth using tunable genetic systems", International Journal of Robust and Nonlinear Control (2021) .

2. I. Ruolo, S. Napolitano, D. Salzano, M. di Bernardo, D. di Bernardo, " Control engineering meets synthetic biology: foundations and applications ", Current Opinion in Systems Biology,  2021.

2020

1. D. Fiore, D. Salzano, E. Cristòbal-Cóppulo, J.M. Olm, M. di Bernardo, "Multicellular feedback control of a genetic toggle-switch in microbial consortia", IEEE Control Systems Letters, 5(1), pp. 151-156, 2021.

2. A. Guarino, D. Fiore, D. Salzano, M. di Bernardo, "Balancing cell populations endowed with a synthetic toggle switch via adaptive pulsatile feedback control", ACS Synthetic Biology, 2020. 

3. F. Della Rossa*, D. Salzano*, A. Di Meglio*, F. De Lellis*, M. Coraggio, C. Calabrese, A. Guarino, R. Cardona, P. De Lellis, D. Liuzza, F. Lo Iudice, G. Russo, M. di Bernardo , "Intermittent yet coordinated regional strategies can alleviate the COVID-19 epidemic: a network model of the Italian case", 2020.

4. B. Shannon, C.G. Zamora-Chimal, L. Postiglione, D. Salzano, C. Grierson, L. Marucci, N.J. Savery, M. di Bernardo, "In vivo Feedback Control of an Antithetic Molecular-Titration Motif in Escherichia coli using Microfluidics", 2020.

2019

1. D. Salzano, D. Fiore, M. di Bernardo, "Ratiometric control for differentiation of cell populations endowed with synthetic toggle switches", IEEE Conference on Decision and Control (CDC), pp. 927-932, Nice, France 2019. 

* Authors contributed equally to the work.