Agostino Guarino

PhD student

Short bio

Agostino Guarino is a PhD student in Information Technologies and Electrical Engineering at the University of Naples Federico II, under the supervision of prof. Mario di Bernardo.

His research deals with the field of Synthetic Biology; in particular,  the two main topics are the external control of microbial populations and the developement of a novel type of bioreactor for multicellular in vivo control experiments.

He got his Master Degree in Automation Engineering cum laude in 2017, after an internship in the section of Control of Cryogenic Facilities at CERN (Geneva). He also worked at the University of Bristol under the supervision of prof. N. Savery, prof. C. Grierson, prof. M. di Bernardo and Dr. L. Marucci. 

About His Research

Publications

1. D. Fiore, F. Della Rossa, A. Guarino, M. di Bernardo, "Feedback ratiometric control of two microbial populations in a single chemostat", IEEE Control Systems Letters, 2021. (biorxiv)

2. F. Della Rossa, D. Salzano, A. Di Meglio, F. De Lellis, M. Coraggio, C. Calabrese, A. Guarino, R. Cardona-Rivera, P. De Lellis, D. Liuzza, F. Lo Iudice, G. Russo, M. di Bernardo, "A network model of Italy shows that intermittent regional strategies can alleviate the COVID-19 epidemic" Nature Communications vol. 11 no. 5106, 2020.

3. A. Guarino, D. Fiore, D. Salzano, M. di Bernardo, "Balancing cell populations endowed with a synthetic toggle switch via adaptive pulsatile feedback control", ACS Synthetic Biology 9 (4), 793-803, 2019.

4. A. Guarino, D. Fiore, M. di Bernardo, "In-silico Feedback Control of a MIMO Synthetic Toggle Switch via Pulse-Width Modulation", European Control Conference (ECC), pp. 680-685, Naples, Italy, 2019. 

5. D. Fiore,A. Guarino A., M. di Bernardo, “Analysis and Control of Genetic Toggle Switches Subject to Periodic Multi-Input Stimulation”, IEEE Control Systems Letters, Special Issue on "Control and Network Theory for Biological Systems", 3(2), pp. 278–283, 2018. 

6. A. Guarino, B. Shannon, L. Marucci, C. Grierson, N. Savery, M. di Bernardo, "A low cost, open source Turbidostat design for in-vivo control experiments in Synthetic Biology", 8th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), pp. 277 - 281, Valencia, Spain, 2019.

7. P. Arpaia, H. Coppier, D. De Paola, M. di Bernardo, A. Guarino, B. Luz Pedemonte, M. Pezzetti, "Comparison of different cryogenic control strategies via simulation applied to a superconducting magnet test bench at CERN", IOP Conference Series: Material Science and Engineering, 278(1), p. e012080, Madison, 2017.