Publications

30. Uddin, N., Warriner, L.W., Pack D.W.*, DeRouchey, J.E.* Enhanced Gene Delivery and CRISPR/Cas9 Homology-Directed Repair in Serum by Minimally Succinylated Polyethylenimine. Molecular Pharmaceutics (2021), in press. (link)

29. Lichtenberg S.S., Nuti, K., DeRouchey, J.E., Tsyusko, O.V., Unrine, J.M.* Efficacy of chitosan/double-stranded RNA polyplex nanoparticles for gene silencing under variable environmental conditions. Environ. Sci.: Nano, 2020, Advance Article. (link)

28. Powell, C.D., Kirchoff, D.C., DeRouchey, J.E., Moseley, H.N.B.* Entropy based analysis of vertebrate sperm protamines sequences: evidence of potential dityrosine and cysteine-tyrosine cross-linking in sperm protamines. BMC Genomics (2020), 21, 277. (link)

27. Fu, X., Song, Y., Masud, A. Nuti, K., DeRouchey, J.E., Richards, C.I.* High-throughput fluorescence correlation spectroscopy enables analysis of surface components of cell-derived vesicles. Anal Bioanal Chem 2020, 412, 2589–2597. (link)

26. Warriner L. W.; Duke, III, J. R.; Pack, D. W.*; DeRouchey, J. E.*, Succinylated Polyethylenimine Derivatives Greatly Enhance Polyplex Serum Stability and Gene Delivery In Vitro. Biomacromolecules 2018, 19 (11), 4348-4357. (link)

25. Hansing, J.; Duke, III, J. R.; Fryman, E. B.; DeRouchey, J. E.*; Netz, R. R.*, Particle Diffusion in Polymeric Hydrogels with Mixed Attractive and Repulsive Interactions. Nano Letters 2018, 18 (8), 5248-5256. (link)

24. An, M.; Tonga, G. Y.; Parkin, S. R.; Rotello, V. M.; DeRouchey, J. E.*, Tuning DNA Condensation with Zwitterionic Polyamidoamine (zPAMAM) Dendrimers. Macromolecules 2017, 50 (20), 8202-8211. (link)

23. Hutchison, J.M.; Rau, D.C.; DeRouchey J.E.* Role of Disulfide Bonds on DNA Packaging Forces in Bull Sperm Chromatin. Biophys J. 2017, 113 (9), 1925-1933. (link)

22. Stocke, N. A.; Zhang, X.; Hilt, J. Z.; DeRouchey, J. E.*, Transport in PEG-Based Hydrogels: Role of Water Content at Synthesis and Crosslinker Molecular Weight. Macromolecular Chemistry and Physics 2017, 218 (3), 1600340. (link)

21.Hansing, J.; Ciemer, C.; Kim, W. K.; Zhang, X.; DeRouchey, J. E.; Netz, R. R., Nanoparticle Filtering in Charged Hydrogels: Effects of Particle Size, Charge Asymmetry and Salt Concentration. European Physics Journal E Soft Matter 2016, 39 (5), 53. (link)

20. Zhang, X.; Hansing, J.; Netz, Roland R.; DeRouchey, J. E.*, Particle Transport through Hydrogels Is Charge Asymmetric. Biophysical Journal 2015, 108 (3), 530-539. (link)

19. Moonschi, F. H.; Effinger, A. K.; Zhang, X.; Martin, W. E.; Fox, A. M.; Heidary, D. K.; DeRouchey, J. E.; Richards, C. I., Cell-Derived Vesicles for Single-Molecule Imaging of Membrane Proteins. Angewandte Chemie 2015, 127 (2), 491-494. (link)

18. An, M.; Parkin, S. R.; DeRouchey, J. E.*, Intermolecular Forces Between Low Generation PAMAM Dendrimer Condensed DNA Helices: Role of Cation Architecture. Soft Matter 2014, 10 (4), 590-599. (link)

17.An, M.; Hutchison, J. M.; Parkin, S. R.; DeRouchey, J. E.*, Role of pH on the Compaction Energies and Phase Behavior of Low Generation PAMAM-DNA Complexes. Macromolecules 2014, 47 (24), 8768–8776. (link)

16. DeRouchey, J.; Hoover, B.; Rau, D. C., A Comparison of DNA compaction by Arginine and Lysine Peptides: A Physical Basis for Arginine Rich Protamines. Biochemistry 2013, 52 (17), 3000-3009. (link)

15. DeRouchey, J. E.*; Rau, D. C., Salt Effects on Condensed Protamine-DNA Assemblies: Anion Binding and Weakening of Attraction. Journal of Physical Chemistry B 2011, 115 (41), 11888-11894. (link)

14. DeRouchey, J. E.*; Rau, D. C., Role of Amino Acid Insertions on Intermolecular Forces Between Arginine Peptide Condensed DNA Helices: Implications for Protamine-DNA Packaging in Sperm. Journal of Biological Chemistry 2011, 286 (49), 41985-41992. (link)

13. Hoenig, D.; DeRouchey, J.*; Jungmann, R.; Koch, C.; Plank, C.; Rädler, J. O., Biophysical Characterization of Copolymer-Protected Gene Vectors. Biomacromolecules 2010, 11 (7), 1802-1809. (link)

12. DeRouchey, J.*; Parsegian, V. A.; Rau, D. C., Cation Charge Dependence of the Forces Driving DNA Assembly. Biophysical Journal 2010, 99 (8), 2608-2615. (link)

11. DeRouchey, J.*; Schmidt, C.; Walker, G. F.; Koch, C.; Plank, C.; Wagner, E.; Rädler, J. O., Monomolecular Assembly of siRNA and Poly(ethylene glycol)-Peptide Copolymers. Biomacromolecules2008, 9 (2), 724-732. (link)

10. Pelisek, J.; Gaedtke, L.; DeRouchey, J.; Walker, G. F.; Niko, S.; Wagner, E., Optimized Lipopolyplex Formulations for Gene Transfer to Human Colon Carcinoma Cells Under In Vitro Conditions. Journal of Gene Medicine 2006, 8 (2), 186-197. (link)

09. DeRouchey, J.*; Walker, G. F.; Wagner, E.; Rädler, J. O., Decorated Rods: A "Bottom-up" Self-Assembly of Monomolecular DNA Complexes. Journal of Physical Chemistry B 2006, 110 (10), 4548-4554. (link)

08. DeRouchey, J.*; Netz, R. R.; Rädler, J. O., Structural investigations of DNA-Polycation Complexes. European Physical Journal E 2005, 16 (1), 17-28. (link)

07. DeRouchey, J.; Thurn-Albrecht, T.; Russell, T. P.; Kolb, R., Block Copolymer Domain Reorientation in an Electric Field: An in-situ Small-Angle X-ray Scattering Study. Macromolecules 2004, 37 (7), 2538-2543. (link)

06. Thurn-Albrecht, T.; DeRouchey, J.; Russell, T. P.; Kolb, R., Pathways Toward Electric Field Induced Alignment of Block Copolymers. Macromolecules 2002, 35 (21), 8106-8110. (link)

05. Xu, T.; Kim, H. C.; DeRouchey, J.; Seney, C.; Levesque, C.; Martin, P.; Stafford, C. M.; Russell, T. P., The Influence of Molecular Weight on Nanoporous Polymer Films. Polymer 2001, 42 (21), 9091-9095. (link)

04. Thurn-Albrecht, T.; Steiner, R.; DeRouchey, J.; Stafford, C. M.; Huang, E.; Bal, M.; Tuominen, M.; Hawker, C. J.; Russell, T., Nanoscopic Templates From Oriented Block Copolymer Films. Advanced Materials 2000, 12 (11), 787-791. (link)

03. Thurn-Albrecht, T.; DeRouchey, J.; Russell, T. P.; Jaeger, H. M., Overcoming Interfacial Interactions with Electric Fields. Macromolecules 2000, 33 (9), 3250-3253. (link)

02. Boal, A. K.; Ilhan, F.; DeRouchey, J. E.; Thurn-Albrecht, T.; Russell, T. P.; Rotello, V. M., Self-Assembly of Nanoparticles into Structured Spherical and Network Aggregates. Nature 2000, 404 (6779), 746-748. (link)

01. Mansky, P.; DeRouchey, J.; Russell, T. P.; Mays, J.; Pitsikalis, M.; Morkved, T.; Jaeger, H., Large-Area Domain Alignment in Block Copolymer Thin Films Using Electric Fields. Macromolecules1998, 31 (13), 4399-4401. (link)