Publication List Prior To 2010:
A. Peer-reviewed Papers - 38 Peer-reviewed papers already published as follows (*Chen, D. - Dequan Chen is the corresponding author):
1. *Fan, Z., Gao, Y., Jia, Z., Deng, Y., and *Chen, D. (2010). Effects of cooling cornea by Low-Temperature Saline Washing on postoperative pain in Photorefractive Keratectomy. Int. J. Functional Informatics and Personalized Medicine, 3 (3): 228-235.
2. *Chen, D. (2009). Genetic variations of ARMS2/HTRA1 locus in 10q26.13 and Age-related Macular degeneration. In: Retinal Degeneration: Causes, Diagnosis and Treatment; edited by Robert B. Catlin; Nova Science Publishers, Inc.; July 2009 (Chapter 6), pp119-130.
3. Edwards, A.O., Chen, D., Fridley B.L., James, K.M., Wu, Y., Abecasis, G., Swaroop, A., Othman, M., Branham, K., Iyenger, S.K., Sivakumaran, T.A., Klein, R., Klein, B. E., and Tosakulwong, N. (2008). Toll-like Receptor Polymorphisms and Age-Related Macular Degeneration. IOVS, 49(4): 1652-9.
4. Langford, M.P., Gosslee, J. M., Chen, D., Misra, R. P., Liang, C., Redens, T.B., and Welbourne, T.C. (2007). Apical accumulation of glutamate in GLAST-1, glutamine synthetase positive ciliary body non-pigmented epithelial cells. Clin. Ophthalmol., 1:43-53.
5. *Chen, D., Langford, M.P., Duggan, C., Madden, B.J., and Edwards, A.O. Expression of Recombinant Protein Encoded by LOC387715 inEscherichia coli. (2007). Protein Expr Purif., 54(2):275-282.
6. Zhang, C., Li, P., Rajendran, A., Deng, Y., and Chen, D. (2006). Parallelization of multicategory support vector machines (PMC-SVM) for classifying microarray data. BMC Bioinformatics, 12 (7 Suppl 4):S15 (1-10).
7. Zeng, G., Aldridge, M. E., Tian, X., Seiler, D., Zhang, X., Jin, Y., Rao, J., Li, W., Chen, D., Langford, M.P., Duggan, C., Wang, R., Belldegrun, A. S. and Dubinett, S. M. (2006). Dendritic cell surface calreticulin is a receptor for tumor-associated antigen NY-ESO-1. J. Immunology, 177(6): 3582-3589.
8. *Chen, D., Texada, D. E., Duggan, C., Deng, Y., Redens, T. B. and Langford, M. P. (2006). Caspase-3 and 7 mediates apoptosis of human conjunctival cells induced by enterovirus 70. Virology, 347: 307-322.
9. Langford, M.P., Chen, D., Gosslee, J., Misra, R. P., Redens, T. B. and Texada, D. E. (2006). Intracameral toxicity of bacterial components muramyl dipeptide and staurosporine; ciliary cysts formation, epithelial cell apoptosis and necrosis. Cutaneous and Ocular Toxicology, 25(2): 85-101.
10. *Chen, D. and Texada, D. E. (2006). Low-usage codons and rare codons of Escherichia coli. Gene Therapy and Molecular Biology, 10: 1-12.
11. *Chen, D., Duggan, C., Texada, D. E., Deng, Y., Liang, C. P. and Langford, M. P. (2005). Induction of apoptosis by enterovirus 70 in human lens epithelial cells. American Journal of Infectious Diseases, 1 (2): 90-106
12. *Chen, D., Texada, D. E., Duggan, C., Liang C., Reden, T.B., Kooragayala, L.M. and Langford, M. (2005). Surface calreticulin mediates muramyl dipeptide induced apoptosis in RK13 Cells. Journal of Biol. Chem., 280 (23): 22425-22436.
13. *Chen, D., Duggan, C., Texada, D. E., Reden, T.B., Kooragayala, L.M. and Langford, M. P. (2005). Immunogenicity of enterovirus 70 capsid protein VP1 and its non-overlapping N- and C-terminal fragments. Antiviral Research, 66 (2-3): 111-117.
14. *Chen, D., Duggan, C., Ganley, J.P., Kooragayala, L.M., Reden, T. B., Texada, D. E. and Langford, M. P. (2004). Expression of enterovirus 70 capsid protein VP1 in Escherichia coli. Protein Expr Purif. 37(2): 426-433.
15. *Chen, D., Duggan, C., Reden, T. B., Kooragayala, L.M., Texada, D. E. and Langford, M. P. (2004). Calreticulin is a binding protein for muramyl dipeptide and peptidoglycan in RK13 Cells. Biochemistry, 43(37): 11796-11801.
16. Langford, M. P., Orillac, R., Chen, D. and Texada, D. E. (2003). Systemic and ocular antibody responses to inactivated acute hemorrhagic conjunctivitis (AHC) virus; enterovirus 70 (EV70). Ocul Immunol Inflamm., 11(3): 197-209.
17. Langford, M. P., Chen, D., Welbourne, T. C., Redens, T. B., Ganley, J. P. and. (2002). Stereo-isomer specific induction of renal cell apoptosis by synthetic muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine). Mol. Cell. Biochem, 236: 63~73.
18. Deng, Y., Lin, C., Zhang, X., Chen, D., Xiao, P. and WU, M. (2000). Arsenic trioxide induced human esophageal cancer EC109 cell apoptosis with downregulation of c-myc gene expression. Acta Academiae Medicinae Sinicae (Zhongguo Yi Xue Ke Xue Yuan Xue Bao), 22(1): 67-70.
19. Zhu, H., Zhu, C., Meng, X., Wang, L., and Chen, D. (2000). Screening of epilepsy-related genes and isolation and identification of cDNAs. J. Tongji Med. Uni., 33 (1): 10-12.
20. Li, W., Wang, X., Zhang, C., Han, X., Chen, D., Zhang, W., Pan, X., Jia, Y., Mao, X., Zhang, R., Zhou, C. and Wu, M. (2000). Genetic epidemiological survey of esophageal cancer in one-tenth of the population of Yangquan city. Chinese Med J, 113(4): 309.
21. Langford, M. P., Chen, D., Neff, A. G., Redens, T. B., Berg, M. E., Ganley, J. P., Dass, P. and Welbourne, T. C. (1999). Intracameral muramyl dipeptide-induced paracellular permeability associated with decreased glutamate transporter and glutamyl-transpeptidase activities. Exp. Eye Res., 68: 591~600.
22. Deng, Y. P., Lin, C., Zhang, X. Y., Chen, D., Xiao, P. G. and Wu, M. (1999). Arsenic trioxide induces programmed cell death of human gastric adenocarcinoma SGC7901 cells and decreases c-myc gene expression. Acta Pharmaceutica Sinica, 34(5): 333~337.
23. Deng, Y. P., Lin, C., Chen, J. P., Liang, X., Chen, D., Xiao, P. G. and Wu, M. (1999). Arsenic trioxide induced human cervical cancer cell apoptosis and effect of bcl-2 overexpression on it. Chinese Journal of Pharmacology and Toxicology, 13(4): 288~293.
24. He, H., Wu, T., Pan, Q., Wu, Y., Gong, X., Nu, Y., Chen, D., and Zhang, G. (1998). Study on the role of HSPs in heat acclimatization and thermotolerance. Chinese Journal of Industrial Hygiene and Occupational Diseases, 16(2): 8-11.
25. Deng, Y. P., Feng, P., Chen, D., Xiao, P. G. (1997). The Role of Fas and FasL in the Cell Apoptosis. Adv. Immunol., 20(4): 213~216.
26. *Chen, D., Wu, T., Yuan, Y., He, H., and Zhang, G., Liu, L., Zhang, M., Yao, H., Wan, X. W. and Li, W. (1996). A study on plasma non-species specific autoantibody in employees working in a automobile engine testing workshop. Chin. J. Prev. Med. (Zhonghua Yu Fang Yi Xue Za Zhi), 30(6): 347-350.
27. *Chen, D., Wang, X., Ding, F., and Wu, M. (1996). Expression of the protein encoded by RA28----cDNA of a new tumor suppresser gene inE. Coli. In: Proceedings of the Annual Meeting of the Chinese Academy of Medical Sciences. United Press of Beijing Medical University and Peking Union Medical College, Beijing. pp 47-51.
28. *Chen, D., Chen, S., Pang, Q., Yuan, Y., He, H., and Zhang, G. (1996). Effects of different combinations of high temperature with CO on the expression of Hsp60 in the brain, heart, liver, spleen and kidney of rat. J. Hygiene Res., 325-328.
29. *Chen, D., Chen, S., Pang, Q., Yuan, Y., He, H., and Zhang, G. (1996). Combined effect of high temperature and carbon monoxide on heat stress protein levels in rat brain and viscera. Chin. J. Prev. Med. (Zhonghua Yu Fang Yi Xue Za Zhi), 30(5): 262-265.
30. Chen, D., Chen, S., Pang, Q., He, H., and Zhang, G. (1996). The gene expression kinetics of Hsps in rat viscera. Railway Occupational Safety, Health & Environmental Protection, 4: 74.
31. Chen, D., Chen, S., Pang, Q., He, H., and Zhang, G. (1996). The combination of high temperature and CO on the gene expression of Hsps.Railway Occupational Safety, Health & Environmental Protection, 4: 76.
32. *Chen, D., Chen, S., Pang, Q., Yuan, Y., He, H., and Zhang, G. (1996). Study on the kinetics of Hsp60 gene expression in brain, heart, liver, spleen, and kidney cells of rats. J. Hygiene Res. 25:257-261.
33. Fan, Z., Wei, H., Wang, Q. and Chen, D. (1995). Retinal pigment epithelial cells promoted the growth of fibroblasts in vitro. Ophthalmologic Res., 131(4): 244-246.
34. *Chen, D. and Zhang, G. (1995). New advances in the study of protein folding and assembly. Adv. Mol. Biol., 17:145-149.
35. *Chen, D. Research on the expression kinetics of Hsp60 and Hsp70 genes of rat viscera. (1995). In: Collected Works of the Century-Spanning Medically Talented Persons. Public Lectures for Beijing Postdoctoral Fellows, Chinese Postdoctoral Council [ed.], Beijing, pp. 28-29.
36. Zhang, G., He, H., Wu, Y., Lu, Y. Q., Gong, X., Wu, T., Chen, D., Gong, P., Chen, S., and Shi, W. X. (1995). Study on the heat shock proteins in occupational medicine. Basic Medical Sciences and Clinics, 15 (2):7-10.
37. *Chen, D., He, H. and Zhang, G. (1995). The role of Hsp70 in the regulation of stress responses. Foreign Medical Sciences (Hygiene Section), 3:136-140.
38. *Chen, D. (1993). The role of HSP70 and GSH on the thermotolerance of in-vitro cultured rat embryos. Journal of Medical Molecular Biology, 16 (2): 97-98
B. Peer-reviewed Academic Conference Abstracts/Papers (Presented as Posters or Oral Presentation):
1. Chen, D. (2009). Oral (paper/conference) presentation. AMD-related Genetic Variations Determine the RNA Expression of ARMS2 (LOC387715) and HTRA1 in Human Eye Tissues. Ocular Diseases & Drug Discovery Conference (Philadelphia, Pennsylvania).
2. Chen, D. and Sun, Y. (2009). Study of Three Genetic Variations in 10q26.13 with RNA Expression Levels of ARMS2 (LOC387715) andHTRA1. ARVO (Fort Lauderdale, Florida).
3. Chen, D. and Edwards, A. O. (2007). Oral (paper/conference) presentation. Genetic Association Study of Toll-Like Receptors for Age-Related Macular Degeneration (AMD). ARVO (Fort Lauderdale, Florida).
4. Chen, D. and Edwards, A. O. (2006). Oral (paper/conference) presentation. Genetic Risk of CFH, LOC387715, BF, C2, TLR4, and ELOVL4for AMD. ARVO Summer Eye Research Conference (SERC) (Fort Meyers, Florida).
5. Chen, D. (2005). Invited oral (conference) presentation. The effects of rare codon and rare codon cluster on the expression of a foreign gene in Escherichia coli. The 8th International Conference on Gene Therapy and Drug Therapy (Crete Island, Greece).
6. Langford, M. P., Chen, D. and Texada, D. E. (2004). Inhibition of bacterial cell wall peptidoglycan and muramyl dipeptide induced apoptosis by cyclooxygenase inhibitors. ARVO annual meeting, Abstract & Poster, O002.
7. Langford, M. P. and Chen, D. (2003). Poster, Nevada. Detection of the apoptotic genes expressed in muramyl dipeptide treated rabbit (RK13) kidney cells by microarray analysis. ASM Conference on Polymicrobial Diseases.
8. Chen, D., Langford, M. P., Duggan, C., Ganley, J. P. and Texada, D. E. (2002). Isolated muramyl dipeptide receptor is identified as a specific cell surface calreticulin. ARVO annual meeting, Abstract & Poster, 2409-B406.
9. Ganley, J. P., Chen, D. and Langford, M. P. (2002). Clearance of cytotoxic bacterial cell wall component (muramyl dipeptide) from rabbit aqueous and blood. ARVO annual meeting, Abstract & Poster, 2249-B246.
10. Langford, M. P., Chen, D. And Dimock, K. D. (2001). Monoclonal antibodies against enterovirus type 70 exhibit interferon-dependent (IDA) or interferon-independent activities (IIA) to protect uninfected cells. Invest. Ophthalmol. Vis. Sci., 42(4): S579.
11. Redens, T. B., Chen, D., Welbourne, T. C. and Langford, M. P. (2001). Two glutamate transporters, EAAT1 and EAAT2, in cultured human lens epithelial cells. Invest. Ophthalmol. Vis. Sci., 42(4): S876
12. Chen, D., Redens, T. B., Ganley, J. P., Texada, D. E. and Langford, M. P. (2001). Apoptosis and g-glutamyl transpeptidase associated with the disruption of blood-conjunctival barrier following topical application of muramyl dipeptide. Invest. Ophthalmol. Vis. Sci., 42(4): S256.
13. Ganley, J. P., Chen, D., Welbourne, T. C. and Langford, M. P. (2000). Intercameral-glutamyl transferase mRNA and activity decrease during muramyl dipeptide-induced acute anterior uveitis. Invest. Ophthalmol. Vis. Sci., 41(4): S380.
14. Langford, M. P., Chen, D., Texada, D. E. and Welbourne, T. C. (2000). Prostaglandin inhibits muramyl dipeptide-induced programmed cell death. Invest. Ophthalmol. Vis. Sci., 41(4): S379
15. Chen, D., Redens, T. B., Welbourne, T. C and Langford, M, P. (2000). Adjuvant muramyl dipeptide (N-acetylmuramyl-L-analyl-D-isoglutamine) induced apoptosis in rabbit kidney cells (Poster). Joint Annual Meeting of Southeastern & South Central Branches of American Society for Microbiology, Little Rock, AR.
16. Langford, M. P., Chen, D., Redens, T. B., Ganley, J. P. and Texada, D. E. (2000). Apoptotic DNA in tears during bacterial cell wall peptidoglycan induced conjunctivitis in rabbits (oral presentation). Joint Annual Meeting of Southeastern & South Central Branches of American Society for Microbiology, Little Rock, AR.
17. Langford, M. P., Chen, D., Polk, T. N., Redens, T., Ganley, J. P. and Welbourne, T. C. (2000). Acute aseptic conjunctivitis (oral presentation). OMIG Meeting, Dallas, TX.
18. Langford, M. P. and Chen, D. (1999). An immmunodominant neutralizing epitope resides in the amino-terminal end of enterovirus 70 capsid protein VP1. Invest. Ophthalmol. Vis. Sci., 40(4): S687.
19. Welbourne, T. C., Chen, D. and Langford, M. P. (1999). Glutamate transporter mRNA in rabbit and monkey ciliary body epithelium. Invest. Ophthalmol. Vis. Sci., 40(4): S498
20. Chen, D. and Langford, M. P. (1998). Immunodominance of the amino-terminus of enterovirus 70 VP1 capsid protein (oral presentation). Joint Annual Meeting of Southeastern & South Central Branches of American Society for Microbiology, Montgomery, AL.
21. Chen, D., Ganley, J. P. and Langford, M. P. (1998). Immunogenicity of recombinant enterovirus 70(EV70) capsid proteins. Invest. Ophthalmol. Vis. Sci., 39(4): S148
22. Chen, D. and Langford, M. P. (1997). Expression and purification of recombinant enterovirus 70(EV70) capsid proteins (oral presentation).Joint Annual Meeting of South Central Branch of American Society for Microbiology and South Central Branch of American Society for Biochemistry, Jackson, MS.