Publications

(Selected Publications)

Liu CSC, Ganguly D. Mechanical Cues for T Cell Activation: Role of Piezo1 Mechanosensors. Critical Reviews in Immunology. 2019. (In press)

Rahaman O, Bhattacharya R, Liu CSC, Raychaudhuri D, Ghosh AR, Bandopadhyay P, Pal S, Goswami RP, Sircar G, Ghosh P, Ganguly D. Cutting Edge: Dysregulated Endocannabinoid-Rheostat for Plasmacytoid Dendritic Cell Activation in a Systemic Lupus Endophenotype. Journal of Immunology. 2019 Mar 15;202(6):1674-1679. doi: 10.4049/jimmunol.1801521.

Paul B, Rahaman O, Roy S, Pal S, Satish S, Mukherjee A, Ghosh AR, Raychaudhuri D, Bhattacharya R, Goon S, Ganguly D#, Talukdar A# (#Corresponding authors). Activity-guided development of potent and selective toll-like receptor 9 antagonists. European Journal of Medicinal Chemistry. 2018 Nov 5;159:187-205. doi: 10.1016/j.ejmech.2018.09.058.

Liu CSC, Raychaudhuri D, Paul B, Chakrabarty Y, Ghosh AR, Rahaman O, Talukdar A, Ganguly D. Cutting Edge: Piezo1 Mechanosensors Optimize Human T Cell Activation. Journal of Immunology. 2018 Feb 15;200(4):1255-1260. doi: 10.4049/jimmunol.1701118.

Nargis T, Kumar K, Ghosh AR, Sharma A, Rudra D, Sen D, Chakrabarti S, Mukhopadhyay S, Ganguly D#, Chakrabarti P# (#Corresponding authors). KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetes. Molecular Metabolism. 2017 Nov;6(11):1529-1539.

Ganguly D#. Do type I interferons link systemic autoimmunities and metabolic syndrome in a pathogenetic continuum? Trends in Immunology. 2018 Jan;39(1):28-43.

Roy S, Mukherjee A, Paul B, Rahaman O, Roy S, Maithri G, Ramya B, Pal S, Ganguly D#, Talukdar A#. Design and development of benzoxazole derivatives with toll-like receptor 9 antagonism. European Journal of Medicinal Chemistry. 2017 Jul 7;134:334-347.

Ghosh AR, Bhattacharya R, Bhattacharya S, Nargis T, Rahaman O, Duttagupta P, Raychaudhuri D, Liu CSC, Roy S, Ghosh P, Khanna S, Chaudhuri T, Tantia O, Haak S, Bandyopadhyay S, Mukhopadhyay S, Chakrabarti P, Ganguly D#. Adipose recruitment and activation of plasmacytoid dendritic cells fuel metaflammation. Diabetes. 2016 Nov;65(11):3440-3452.

Meller S, Di Domizio J, Voo KS, Friedrich HC, Chamilos G, Ganguly D, Conrad C, Gregorio J, Le Roy D, Roger T, Ladbury JE, Homey B, Watowich S, Modlin RL, Kontoyiannis DP, Liu YJ, Arold ST, Gilliet M. T helper 17 cells promote microbial killing and innate immune sensing of DNA via interleukin-26. Nature Immunology. 2015 Sep;16(9):970-9.

Lande R*, Chamilos G*, Ganguly D*, Demaria O, Frasca L, Durr S, Conrad C, Schröder J, Gilliet M (*Equal Contribution). Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self-DNA. European Journal of Immunology. 2015 Jan;45(1):203-13.

Sisirak V*, Ganguly D*, Lewis KL, Couillault C, Tanaka L, Bolland S, D'Agati V, Elkon KB, Reizis B (*Equal Contribution). Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus. Journal of Experimental Medicine. 2014 Sep 22;211(10):1969-76. [Epub ahead of print]

Highlighted in Nature Reviews Rheumatology, Onuora S, September 2014.

Ganguly D, Haak S, Sisirak V, Reizis B. Role of dendritic cells in autoimmunity. Nature Reviews Immunology. 2013 Aug;13(8):566-77.

Di Domizio J, Dorta-Estremera S, Gagea M, Ganguly D, Meller S, Li P, Zhao B, Tan FK, Bi L, Gilliet M, Cao W. Nucleic acid-containing amyloid fibrils potently induce type I interferon and stimulate systemic autoimmunity. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14550-5.

Lande R, Ganguly D*, Facchinetti V*, Frasca L, Conrad C, Gregorio J, Meller S, Chamilos G, Sebasigari R, Riccieri V, Bassett R, Amuro H, Fukuhara S, Ito T, Liu YJ, Gilliet M. (*Equal Contribution) Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Science Translational Medicine. 2011 Mar 9;3(73):73ra19.

Commentary in New England Journal of Medicine, 2011, 365(8):758-60.

Highlighted in Nature Reviews Rheumatology, Warde N, May 2011.

Featured in Nature Reviews Key Advances in Medicine, 2012.

Featured in Nature Reviews Rheumatology Year in Review 2011, Dorner T, February 2012.

Ganguly D, Chamilos G, Lande R, Gregorio J, Meller S, Facchinetti V, Homey B, Barrat FJ, Zal T, Gilliet M. Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. Journal of Experimental Medicine. 2009 Aug 31;206(9):1983-94.

Recommended by Faculty1000 with FFa factor of 12.

Chamilos G, Ganguly D, Lande R, Gregorio J, Meller S, Goldman WE, Gilliet M, Kontoyiannis DP. Generation of IL-23 producing dendritic cells (DCs) by airborne fungi regulates fungal pathogenicity via the induction of T(H)-17 responses. PLoS One. 2010 Sep 23;5(9):e12955.

Ganguly D, Paul K, Bagchi J, Rakshit S, Mandal L, Bandyopadhyay G, Bandyopadhyay S. Granulocyte-macrophage colony-stimulating factor drives monocytes to CD14low CD83+ DCSIGN- interleukin-10-producing myeloid cells with differential effects on T-cell subsets. Immunology. 2007 Aug;121(4):499-507.

Citations